Lack of suppressed renal thrombomodulin expression in a septic rat model with glomerular thrombotic microangiopathy.

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Published in Lab Invest on June 01, 1994

Authors

Z Laszik1, C W Carson, T Nadasdy, L D Johnson, M R Lerner, D J Brackett, C T Esmon, F G Silva

Author Affiliations

1: Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City.

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Action of light on frog pigment cells in culture. Pigment Cell Res (1990) 1.66

A polypeptide region of bovine prothrombin specific for binding to phospholipids. Proc Natl Acad Sci U S A (1973) 1.65

A new vitamin K-dependent protein. A phospholipid-binding zymogen of a serine esterase. J Biol Chem (1976) 1.64

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Vitamin K-dependent carboxylase. Requirements of the rat liver microsomal enzyme system. J Biol Chem (1976) 1.53

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Proliferative activity of cyst epithelium in human renal cystic diseases. J Am Soc Nephrol (1995) 1.52

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Normal murine melanocytes in culture. In Vitro Cell Dev Biol (1987) 1.47

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Smoothened activates Galphai-mediated signaling in frog melanophores. J Biol Chem (2000) 1.42

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The active site of blood coagulation factor Xa. Its distance from the phospholipid surface and its conformational sensitivity to components of the prothrombinase complex. J Biol Chem (1987) 1.36

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Identification of functional endothelial protein C receptor in human plasma. J Clin Invest (1997) 1.31

Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin. Blood (2000) 1.30

Protein C. Prog Hemost Thromb (1984) 1.30

Mechanisms by which soluble endothelial cell protein C receptor modulates protein C and activated protein C function. J Biol Chem (2000) 1.29

The endothelial cell protein C receptor. Inhibition of activated protein C anticoagulant function without modulation of reaction with proteinase inhibitors. J Biol Chem (1996) 1.28

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Reconstitution of the human endothelial cell protein C receptor with thrombomodulin in phosphatidylcholine vesicles enhances protein C activation. J Biol Chem (1999) 1.27

Association of renal injury with increased oxygen free radical activity and altered nitric oxide metabolism in chronic experimental hemosiderosis. Lab Invest (2000) 1.26

Protein S alters the active site location of activated protein C above the membrane surface. A fluorescence resonance energy transfer study of topography. J Biol Chem (1997) 1.24

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Expression cloning of a high-affinity melatonin receptor from Xenopus dermal melanophores. Proc Natl Acad Sci U S A (1994) 1.23

cDNA sequence of the rat U snRNP-associated protein N: description of a potential Sm epitope. EMBO J (1989) 1.22

The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity. J Biol Chem (1992) 1.21

Tubular atrophy in the end-stage kidney: a lectin and immunohistochemical study. Hum Pathol (1994) 1.20