Published in Postgrad Med J on June 01, 1994
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Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet (1994) 5.58
Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H). Proc Natl Acad Sci U S A (1990) 4.59
Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad Sci U S A (1993) 4.57
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The antiphospholipid syndrome: ten years on. Lancet (1993) 3.10
Anticoagulant protein C pathway defective in majority of thrombophilic patients. Blood (1993) 2.29
Homozygous protein C deficiency manifested by massive venous thrombosis in the newborn. N Engl J Med (1984) 2.26
Congenital protein C deficiency and venous thromboembolism. A study of three Dutch families. N Engl J Med (1983) 2.03
Measurement of fibrinopeptide A in human blood. J Clin Invest (1974) 2.01
Thromboembolic disease--critical evaluation of laboratory investigation. Thromb Haemost (1992) 1.93
Thromboembolism in patients with the 'lupus'-type circulating anticoagulant. Arch Intern Med (1984) 1.92
Familial protein S deficiency is associated with recurrent thrombosis. J Clin Invest (1984) 1.84
Plasma protein S deficiency in familial thrombotic disease. Blood (1984) 1.82
Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med (1987) 1.79
Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemost (1991) 1.55
Hereditary protein S deficiency: clinical manifestations. Ann Intern Med (1987) 1.53
Deficient t-PA release and elevated PA inhibitor levels in patients with spontaneous or recurrent deep venous thrombosis. Thromb Haemost (1987) 1.44
Lupus anticoagulants and thrombosis. A study of 25 cases and review of the literature. Haemostasis (1985) 1.34
The pathophysiology of the prethrombotic state in humans: insights gained from studies using markers of hemostatic system activation. Blood (1987) 1.31
The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis. Thromb Haemost (1988) 1.17
Inherited predisposition to thrombosis. Cell (1993) 1.05
Neonatal purpura fulminans: a genetic disorder related to the absence of protein C in blood. Blood (1985) 1.01
The relationship of antiphospholipid antibodies to thromboembolic disease in systemic lupus erythematosus: a cross-sectional study. Thromb Haemost (1991) 1.00
Protein C deficiency: a database of mutations. For the Protein C & S Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost (1993) 0.98
Hereditary deficiency of antithrombin III, protein C and protein S: prevalence in patients with a history of venous thrombosis and criteria for rational patient screening. Blood Coagul Fibrinolysis (1992) 0.94
Antithrombin III mutation database: first update. For the Thrombin and its Inhibitors Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost (1993) 0.92
Hereditary dysfibrinogenemia. Clin Chem (1985) 0.91
Different prevalence of thromboembolism in the subtypes of congenital antithrombin III deficiency: review of 404 cases. Thromb Haemost (1987) 0.87
Hypercoagulability--a new cofactor in the protein C anticoagulant pathway. N Engl J Med (1994) 0.86
Markers of procoagulant imbalance in patients with inherited thrombophilic syndromes. Thromb Haemost (1992) 0.84
Antithrombin Oslo: type Ib classification of the first reported antithrombin-deficient family, with a review of hereditary antithrombin variants. Thromb Haemost (1988) 0.82
Molecular characterization of antithrombin III (ATIII) variants using polymerase chain reaction. Identification of the ATIII Charleville as an Ala 384 Pro mutation. J Clin Invest (1989) 0.81
Thrombin generation in acute promyelocytic leukemia. Blood (1984) 0.81
Antithrombin III: a database of mutations. Thromb Haemost (1991) 0.80
Protein CVermont: symptomatic type II protein C deficiency associated with two GLA domain mutations. Blood (1992) 0.80
Investigation of a congenital abnormal plasminogen, Frankfurt I, and its relationship to thrombosis. Thromb Haemost (1986) 0.78
Congenital thrombophilia among patients with venous thromboembolism. Blood Coagul Fibrinolysis (1992) 0.78
The molecular genetics of familial venous thrombosis. Blood Rev (1991) 0.77
Congenital deficiency of plasminogen and its relationship to venous thrombosis. Thromb Haemost (1988) 0.76
The utility of plasma fibrinopeptide assays. Thromb Haemost (1989) 0.76
Protein C activity in healthy volunteers--influence of age, sex, smoking and oral contraceptives. Thromb Haemost (1993) 0.76
Congenital thrombophilia. Baillieres Clin Obstet Gynaecol (1997) 0.76
Factor V Leiden: should all women be screened prior to commencing the contraceptive pill? Blood Rev (1999) 0.76