Published in Clin Pharmacol Ther on July 01, 1994
An updated meta-analysis of nicotine preloading for smoking cessation: investigating mediators of the effect. Psychopharmacology (Berl) (2011) 2.48
Nicotine and nonnicotine factors in cigarette addiction. Psychopharmacology (Berl) (2005) 2.27
Bupropion enhances brain reward function and reverses the affective and somatic aspects of nicotine withdrawal in the rat. Psychopharmacology (Berl) (2003) 1.49
Nicotine response genetics in the zebrafish. Proc Natl Acad Sci U S A (2009) 1.45
N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity. J Pharmacol Exp Ther (2008) 1.44
Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats. Psychopharmacology (Berl) (2005) 1.35
Nicotine as a typical drug of abuse in experimental animals and humans. Psychopharmacology (Berl) (2005) 1.35
Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras. Neuropharmacology (2008) 1.25
Nicotine dependence and its risk factors among users of veterans health services, 2008-2009. Prev Chronic Dis (2011) 1.12
Nicotinic receptor-based therapeutics and candidates for smoking cessation. Biochem Pharmacol (2009) 1.09
Neuronal nicotinic acetylcholine receptors as pharmacotherapeutic targets for the treatment of alcohol use disorders. CNS Neurol Disord Drug Targets (2010) 1.06
Mecamylamine attenuates cue-induced reinstatement of nicotine-seeking behavior in rats. Neuropsychopharmacology (2006) 1.04
Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors. J Pharmacol Exp Ther (2010) 1.03
Mecamylamine, dihydro-beta-erythroidine, and dextromethorphan block conditioned responding evoked by the conditional stimulus effects of nicotine. Pharmacol Biochem Behav (2009) 1.00
Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence. Nebr Symp Motiv (2009) 1.00
Effects of varenicline on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys. J Pharmacol Exp Ther (2011) 0.98
Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo. Br J Pharmacol (2007) 0.97
Mechanism-based medication development for the treatment of nicotine dependence. Acta Pharmacol Sin (2009) 0.91
The duration of nicotine withdrawal-associated deficits in contextual fear conditioning parallels changes in hippocampal high affinity nicotinic acetylcholine receptor upregulation. Neuropharmacology (2012) 0.90
Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release. Bioorg Med Chem Lett (2008) 0.89
Effects of the nicotinic receptor antagonist mecamylamine on ad-lib smoking behavior, topography, and nicotine levels in smokers with and without schizophrenia: a preliminary study. Schizophr Res (2009) 0.88
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Preclinical Pharmacology, Efficacy and Safety of Varenicline in Smoking Cessation and Clinical Utility in High Risk Patients. Drug Healthc Patient Saf (2010) 0.86
Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist. Pharmacol Biochem Behav (2012) 0.85
Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation. Ann N Y Acad Sci (2014) 0.84
Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity. AAPS J (2005) 0.84
Nicotinic receptor antagonists as treatments for nicotine abuse. Adv Pharmacol (2014) 0.83
Neuroadaptation in nicotine addiction: update on the sensitization-homeostasis model. Brain Sci (2012) 0.83
Potential therapeutic uses of mecamylamine and its stereoisomers. Pharmacol Biochem Behav (2013) 0.82
Structure-activity relationship studies of sulfonylpiperazine analogues as novel negative allosteric modulators of human neuronal nicotinic receptors. J Med Chem (2011) 0.81
Smoking cessation therapy with varenicline. Int J Chron Obstruct Pulmon Dis (2008) 0.81
3D-QSAR and 3D-QSSR models of negative allosteric modulators facilitate the design of a novel selective antagonist of human α4β2 neuronal nicotinic acetylcholine receptors. Bioorg Med Chem Lett (2011) 0.80
The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices. Biochem Pharmacol (2009) 0.80
QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum. Bioorg Med Chem (2009) 0.78
Defining the putative inhibitory site for a selective negative allosteric modulator of human α4β2 neuronal nicotinic receptors. ACS Chem Neurosci (2012) 0.77
Translating laboratory discovery to the clinic: from nicotine and mecamylamine to Tourette's, depression, and beyond. Physiol Behav (2012) 0.76
Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse. Prog Neuropsychopharmacol Biol Psychiatry (2015) 0.75
Supplemental nicotine preloading for smoking cessation in posttraumatic stress disorder: Results from a randomized controlled trial. Addict Behav (2016) 0.75
Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial. Trials (2014) 0.75
A randomised double-blind placebo-controlled phase II study of AGI004 for control of chemotherapy-induced diarrhoea. Br J Cancer (2013) 0.75
Partial nicotinic acetylcholine (alpha4beta2) agonists as promising new medications for smoking cessation. Indian J Pharmacol (2008) 0.75
Mecamylamine Treatment for Alcohol Dependence: A Randomized Controlled Trial. Addiction (2017) 0.75
Serious complications of topical mitomycin-C after pterygium surgery. Ophthalmology (1992) 6.62
Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science (1999) 4.70
Cognitive effects of nicotine. Biol Psychiatry (2001) 2.41
The safety of transdermal nicotine as an aid to smoking cessation in patients with cardiac disease. N Engl J Med (1996) 2.32
Differential effects of ethanol on memory in adolescent and adult rats. Alcohol Clin Exp Res (1998) 2.05
Smoking behavior on the first day of a quit attempt predicts long-term abstinence. Arch Intern Med (1997) 1.83
Dissociating nicotine and nonnicotine components of cigarette smoking. Pharmacol Biochem Behav (2000) 1.81
Nicotine skin patch treatment increases abstinence, decreases withdrawal symptoms, and attenuates rewarding effects of smoking. J Clin Psychopharmacol (1994) 1.73
Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. Neurology (2012) 1.67
Binge pattern ethanol exposure in adolescent and adult rats: differential impact on subsequent responsiveness to ethanol. Alcohol Clin Exp Res (2000) 1.59
Nicotine and attention in adult attention deficit hyperactivity disorder (ADHD). Psychopharmacol Bull (1996) 1.58
Inter-relationships between conditioned and primary reinforcement in the maintenance of cigarette smoking. Br J Addict (1991) 1.52
Smoking in Vietnam combat veterans with post-traumatic stress disorder. J Trauma Stress (1995) 1.43
Oxidative stress in toxicology: established mammalian and emerging piscine model systems. Environ Health Perspect (1998) 1.41
Prevention of muscle cramps in haemodialysis patients by quinine sulphate. Lancet (1976) 1.40
Dissociating the nicotine and airway sensory effects of smoking. Pharmacol Biochem Behav (1996) 1.39
Nicotine-mecamylamine treatment for smoking cessation: the role of pre-cessation therapy. Exp Clin Psychopharmacol (1998) 1.38
Arterial nicotine kinetics during cigarette smoking and intravenous nicotine administration: implications for addiction. Drug Alcohol Depend (1999) 1.32
Blockade of smoking satisfaction using the peripheral nicotinic antagonist trimethaphan. Pharmacol Biochem Behav (1999) 1.30
Gentamicin and renal failure. Lancet (1972) 1.27
Impairment of semantic and figural memory by acute ethanol: age-dependent effects. Alcohol Clin Exp Res (1998) 1.27
Effects of hypotonic saline loading in hydrated dog: evidence for a saline-induced limit on distal tubular sodium transport. J Clin Invest (1967) 1.26
Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia. Neuropsychopharmacology (1996) 1.26
Individual differences in smoking reward from de-nicotinized cigarettes. Nicotine Tob Res (2001) 1.21
Effects of halothane on synaptogenesis and learning behavior in rats. Exp Neurol (1985) 1.19
Nicotinic system involvement in Alzheimer's and Parkinson's diseases. Implications for therapeutics. Drugs Aging (1997) 1.16
Transdermal nicotine facilitates smoking cessation. Clin Pharmacol Ther (1990) 1.15
Haloperidol increases smoking in patients with schizophrenia. Psychopharmacology (Berl) (1995) 1.14
Four-week nicotine skin patch treatment effects on cognitive performance in Alzheimer's disease. Psychopharmacology (Berl) (1999) 1.13
Parathyroid variants: US evaluation. Radiology (1987) 1.10
Sleep disturbance and PTSD. Am J Psychiatry (1989) 1.08
Nicotinic antagonist administration into the ventral hippocampus and spatial working memory in rats. Neuroscience (1997) 1.08
Role of nicotine dose and sensory cues in the regulation of smoke intake. Pharmacol Biochem Behav (1993) 1.08
Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat. Exp Neurol (1997) 1.07
Airway sensory replacement combined with nicotine replacement for smoking cessation. A randomized, placebo-controlled trial using a citric acid inhaler. Chest (1995) 1.07
Inhalation of vapor from black pepper extract reduces smoking withdrawal symptoms. Drug Alcohol Depend (1994) 1.05
Effects of halothane on the development of rat brain: a golgi study of dendritic growth. Exp Neurol (1985) 1.03
Glutamate and nicotinic receptor interactions in working memory: importance for the cognitive impairment of schizophrenia. Neuroscience (2011) 1.03
Effects of unilateral renal arterial constriction on tubular reabsorption of sodium and water during an osmotic diuresis. J Clin Invest (1965) 1.01
Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: persisting effects on locomotor activity, learning and nicotine self-administration. Neuroscience (2008) 1.01
Saliva nicotine as an index of plasma levels in nicotine skin patch users. Ther Drug Monit (1993) 1.00
Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze. Pharmacol Biochem Behav (2001) 0.99
Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions. Brain Res Dev Brain Res (1992) 0.97
Predicting response to amitriptyline in posttraumatic stress disorder. Am J Psychiatry (1993) 0.97
Ventral hippocampal dopamine D1 and D2 systems and spatial working memory in rats. Neuroscience (1999) 0.97
Prenatal cocaine and/or nicotine exposure in rats: preliminary findings on long-term cognitive outcome and genital development at birth. Neurotoxicol Teratol (1997) 0.95
Acute effects of nicotine and mecamylamine on tobacco withdrawal symptoms, cigarette reward and ad lib smoking. Pharmacol Biochem Behav (2001) 0.95
The effect of sleeved arms on oscillometric blood pressure measurement. J Gen Intern Med (1993) 0.95
The nicotine patch in smoking cessation. A randomized trial with telephone counseling. Arch Intern Med (1993) 0.93
Psychopharmacological investigations of a lead-induced long-term cognitive deficit in monkeys. Psychopharmacology (Berl) (1987) 0.93
Effects of perinatal PCB exposure on discrimination-reversal learning in monkeys. Neurotoxicol Teratol (1989) 0.93
Mecamylamine increases nicotine preference and attenuates nicotine discrimination. Pharmacol Biochem Behav (1989) 0.92
Chondroitin sulfate for corneal preservation at 4 degrees C. Evaluation by electron microscopy. Arch Ophthalmol (1986) 0.92
Ventral hippocampal alpha4beta2 nicotinic receptors and chronic nicotine effects on memory. Neuropharmacology (2000) 0.92
Latino physician supply in California: sources, locations, and projections. Acad Med (2000) 0.92
Nicotinic, muscarinic and dopaminergic actions in the ventral hippocampus and the nucleus accumbens: effects on spatial working memory in rats. Brain Res (1996) 0.91
Erythrocytosis associated with chronic renal disease. Arch Intern Med (1974) 0.91
Hippocampal long-term potentiation and spatial learning in the rat: effects of GABAB receptor blockade. Neuroscience (1996) 0.90
A new chromogenic substrate for subtilisin. Anal Biochem (1974) 0.89
Chronic nicotine and withdrawal effects on body weight and food and water consumption in female rats. Physiol Behav (1987) 0.88
Alcohol removal of the epithelium for excimer laser ablation: outcomes analysis. J Cataract Refract Surg (1997) 0.88
Platelet monoamine oxidase, smoking cessation, and tobacco withdrawal symptoms. Nicotine Tob Res (2001) 0.88
Aorto-coronary bypass graft surgery in a patient on home hemodialysis. Clin Nephrol (1975) 0.87
Long-term lead effects on the Hamilton Search Task and delayed alternation in monkeys. Neurobehav Toxicol Teratol (1986) 0.86
Moraxella nonliquefaciens endophthalmitis after trabeculectomy. Am J Ophthalmol (1985) 0.86
Central airway obstruction due to cytomegalovirus-induced necrotizing tracheitis in a patient with AIDS. Am Rev Respir Dis (1990) 0.86
Nicotinic receptors in the habenula: importance for memory. Neuroscience (2009) 0.86
Diet therapy for narcolepsy. Neurology (2004) 0.86
Nicotinic treatment for degenerative neuropsychiatric disorders such as Alzheimer's disease and Parkinson's disease. Behav Brain Res (2000) 0.85
Behavioral evaluation of perinatal PCB exposure in rhesus monkeys: fixed-interval performance and reinforcement-omission. Neurobehav Toxicol Teratol (1986) 0.85
Contrasting effects of centromedial and basolateral amygdaloid lesions on stress-related responses in the rat. Physiol Behav (1990) 0.85
Topical mitomycin-C for pterygia: is single application appropriate? Ophthalmic Surg Lasers (1997) 0.84
The development of substance-abuse curricular content by five North Carolina schools. Acad Med (1998) 0.84
Naltrexone blockade of nicotine effects in cigarette smokers. Psychopharmacology (Berl) (1999) 0.84
Nicotine enhances stimulus detection performance of middle- and old-aged rats: a longitudinal study. Pharmacol Biochem Behav (2000) 0.84
Altered serum clearance of intravenously administered clindamycin phosphate in patients with uremia. J Clin Pharmacol (1974) 0.84
Acid-base analysis of individuals following two weight loss diets. Eur J Clin Nutr (2007) 0.84
Impairment of radial-arm maze performance in rats following lesions involving the cholinergic medial pathway: reversal by arecoline and differential effects of muscarinic and nicotinic antagonists. Neuroscience (1991) 0.83
Psychophysiological interactions between caffeine and nicotine. Pharmacol Biochem Behav (1991) 0.83
Penetrating keratoplasty for pseudophakic bullous keratopathy. Management of the intraocular lens. Ophthalmology (1988) 0.82
Startle and prepulse inhibition as a function of background noise: a computational and experimental analysis. Behav Brain Res (2006) 0.82
Evaluation of corneal topography: past, present and future trends. Can J Ophthalmol (1992) 0.81
The effect of pre- or postnatal lead exposure on Hamilton Search Task in monkeys. Neurobehav Toxicol Teratol (1983) 0.81
Attention as a target of intoxication: insights and methods from studies of drug abuse. Neurotoxicol Teratol (2000) 0.81
Corneal cooling and rehydration during photorefractive keratectomy to reduce postoperative corneal haze. J Refract Surg (1999) 0.81
Improvement of gastroesophageal reflux disease after initiation of a low-carbohydrate diet: five brief case reports. Altern Ther Health Med (2001) 0.81
Effects of chronic sodium depletion on tubular sodium and water reabsorption in the dog. Am J Physiol (1974) 0.81
Scopolamine effects on Hamilton search task performance in monkeys. Pharmacol Biochem Behav (1986) 0.81
The polyuria of paroxysmal atrial tachycardia. Circulation (1974) 0.81