Z S Derewenda

Author PubWeight™ 49.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A serine protease triad forms the catalytic centre of a triacylglycerol lipase. Nature 1990 3.73
2 A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex. Nature 1991 3.29
3 The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component. J Biol Chem 1995 1.93
4 Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase. Biochemistry 1992 1.86
5 Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI. Acta Crystallogr D Biol Crystallogr 2001 1.56
6 Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase. Nat Struct Biol 1999 1.49
7 Crystal structure of the Escherichia coli thioesterase II, a homolog of the human Nef binding enzyme. Nat Struct Biol 2000 1.45
8 Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer. Nature 1997 1.42
9 Crystal structure of RhoA-GDP and its functional implications. Nat Struct Biol 1997 1.42
10 A novel variant of the catalytic triad in the Streptomyces scabies esterase. Nat Struct Biol 1995 1.41
11 Crystal structure, at 2.6-A resolution, of the Streptomyces lividans xylanase A, a member of the F family of beta-1,4-D-glycanases. J Biol Chem 1994 1.41
12 Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A. Structure 2000 1.32
13 Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar. J Lipid Res 1994 1.26
14 How RhoGDI binds Rho. Acta Crystallogr D Biol Crystallogr 1999 1.17
15 Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric g protein-coupled signaling to Rho GTPases. Structure 2001 1.13
16 Structure of a myristoyl-ACP-specific thioesterase from Vibrio harveyi. Biochemistry 1994 1.13
17 An unusual buried polar cluster in a family of fungal lipases. Nat Struct Biol 1994 1.09
18 Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method. Acta Crystallogr B 1991 1.06
19 Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution. Structure 1998 1.06
20 Expression, purification, and crystallization of the RGS-like domain from the Rho nucleotide exchange factor, PDZ-RhoGEF, using the surface entropy reduction approach. Protein Expr Purif 2001 1.01
21 Substrate specificity in glycoside hydrolase family 10. Structural and kinetic analysis of the Streptomyces lividans xylanase 10A. J Biol Chem 2000 1.00
22 The name is bond--H bond. Nat Struct Biol 1999 0.98
23 Solution of the structure of Aspergillus niger acid alpha-amylase by combined molecular replacement and multiple isomorphous replacement methods. Acta Crystallogr B 1991 0.98
24 Current progress in crystallographic studies of new lipases from filamentous fungi. Protein Eng 1994 0.94
25 Conversion of serine-114 to cysteine-114 and the role of the active site nucleophile in acyl transfer by myristoyl-ACP thioesterase from Vibrio harveyi. Biochemistry 1996 0.92
26 Probing the substrate specificity of the intracellular brain platelet-activating factor acetylhydrolase. Protein Eng 1999 0.89
27 Preparation and crystal structure of the recombinant alpha(1)/alpha(2) catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib. Protein Eng 2001 0.85
28 Structure of the BH domain from graf and its implications for Rho GTPase recognition. J Biol Chem 2000 0.84
29 Domain identification of hormone-sensitive lipase by circular dichroism and fluorescence spectroscopy, limited proteolysis, and mass spectrometry. J Biol Chem 1999 0.83
30 Homologs of the alpha- and beta-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome. Proteins 2000 0.83
31 The consequences of engineering an extra disulfide bond in the Penicillium camembertii mono- and diglyceride specific lipase. Protein Eng 1996 0.82
32 Crystallization of a novel esterase which inactivates the macrolide toxin brefeldin A. Acta Crystallogr D Biol Crystallogr 1996 0.81
33 The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib). Protein Eng 2000 0.80
34 Crystallization and preliminary crystallographic studies of the precursor and mature forms of a neutral lipase from the fungus Rhizopus delemar. Proteins 1994 0.79
35 A twist in the tale of lipolytic enzymes. Nat Struct Biol 1995 0.79
36 Crystallization of the malonyl coenzyme A-acyl carrier protein transacylase from Escherichia coli. J Mol Biol 1994 0.78
37 Expression, purification and crystallization of a BH domain from the GTPase regulatory protein associated with focal adhesion kinase. Acta Crystallogr D Biol Crystallogr 1999 0.78
38 Crystallization of thioesterase II from Escherichia coli. J Mol Biol 1994 0.77
39 Crystallization and preliminary crystallographic data of a Streptomyces scabies extracellular esterase. J Mol Biol 1992 0.77
40 Crystallization of canine cardiac calsequestrin. J Mol Biol 1994 0.77
41 Structure of the gangrene alpha-toxin: the beauty in the beast. Nat Struct Biol 1998 0.76
42 Crystallization of human oxyhaemoglobin from poly(ethylene glycol) solutions. Biochem J 1978 0.75
43 Expression, purification and crystallization of the Vibrio harveyi acyltransferase. J Mol Biol 1992 0.75