PubRank

M P Vitek

Author PubWeight™ 53.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice. J Cell Sci 2001 2.82
2 Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells. Proc Natl Acad Sci U S A 1989 2.48
3 Recombinant human interleukin 1 alpha: purification and biological characterization. J Immunol 1986 2.24
4 Microvascular injury and blood-brain barrier leakage in Alzheimer's disease. Neurobiol Aging 2006 2.03
5 Transthyretin sequesters amyloid beta protein and prevents amyloid formation. Proc Natl Acad Sci U S A 1994 1.94
6 Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades. FASEB J 2001 1.75
7 Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease. Neuroscience 2010 1.70
8 In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants. Biochemistry 2000 1.46
9 The isolation of ecdysterone inducible genes by hybridization subtraction chromatography. Nucleic Acids Res 1981 1.43
10 Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53. J Biol Chem 2000 1.36
11 NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 2006 1.27
12 Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy. Oncogene 2011 1.26
13 Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease. Neuroscience 2009 1.15
14 Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radic Biol Med 2001 1.14
15 Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix. Proc Natl Acad Sci U S A 1999 1.07
16 An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer's disease pathology following closed head injury: evidence of pharmacogenomic interaction. Neuroscience 2006 1.02
17 Steroid and high-temperature induction of the small heat-shock protein genes in Drosophila. J Mol Biol 1984 1.01
18 Apolipoprotein E-derived peptides reduce CNS inflammation: implications for therapy of neurological disease. Acta Neurol Scand Suppl 2006 1.00
19 Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1. J Biol Chem 2000 0.96
20 Interleukin-1 stimulates the beta-amyloid precursor protein promoter. Cell Mol Neurobiol 1990 0.96
21 Microglial contribution to oxidative stress in Alzheimer's disease. Ann N Y Acad Sci 2000 0.96
22 Interleukin-1 beta decreases acetylcholine measured by microdialysis in the hippocampus of freely moving rats. Brain Res 1991 0.95
23 The release of Alzheimer's disease beta amyloid peptide is reduced by phorbol treatment. J Biol Chem 1994 0.94
24 Mechanisms of cell death governed by the balance between nitrosative and oxidative stress. Ann N Y Acad Sci 2000 0.94
25 Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides. J Biol Chem 1999 0.91
26 Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport. Biochim Biophys Acta 2001 0.90
27 A pathway of neuronal apoptosis induced by hypoxia/reoxygenation: roles of nuclear factor-kappaB and Bcl-2. J Neurochem 2000 0.89
28 Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity. Oncogene 2009 0.89
29 Release of amino-terminal fragments from amyloid precursor protein reporter and mutated derivatives in cultured cells. J Biol Chem 1992 0.88
30 Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brain. Brain Res Mol Brain Res 2001 0.87
31 Effects of continuous diazepam administration on GABAA subunit mRNA in rat brain. J Mol Neurosci 1990 0.87
32 Apolipoprotein E4 stimulates cAMP response element-binding protein transcriptional activity through the extracellular signal-regulated kinase pathway. J Biol Chem 2000 0.87
33 APOE genotype affects outcome in a murine model of sepsis: implications for a new treatment strategy. Anaesth Intensive Care 2009 0.86
34 Quantitative measurement of alternatively spliced amyloid precursor protein mRNA expression in Alzheimer's disease and normal brain by S1 nuclease protection analysis. Neurobiol Aging 1992 0.85
35 Early AGEing and Alzheimer's. Nature 1995 0.83
36 Transcriptional regulation of the mouse presenilin-1 gene. J Biol Chem 1997 0.83
37 The role of Alzheimer's disease-related presenilin 1 in intercellular adhesion. Exp Cell Res 2001 0.83
38 Differential expression of gamma-aminobutyric acidA receptor subunits. Mol Pharmacol 1990 0.82
39 Stimulation of cytoplasmic actin gene transcription and translation in cultured Drosophila cells by ecdysterone. J Biol Chem 1984 0.80
40 Focusing on IL-1-promotion of beta-amyloid precursor protein synthesis as an early event in Alzheimer's disease. Neurobiol Aging 1989 0.80
41 Enzymatic generation of the amino terminus of the beta-amyloid peptide. J Biol Chem 1993 0.79
42 [Protein transduction domain peptide mediates delivery to the brain via the blood-brain barrier in Drosophila]. Biomed Khim 2009 0.78
43 A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs. Neurobiol Aging 1992 0.78
44 [Studying pathogenesis of Alzheimer's disease in a Drosophila melanogaster model: human APP overexpression in the brain of transgenic flies leads to deficit of the synaptic protein synaptotagmin]. Genetika 2009 0.77
45 Transcript length heterogeneity at the small heat shock protein genes of Drosophila. J Mol Biol 1985 0.77
46 Expression of the apolipoprotein E gene does not affect motor recovery after sensorimotor cortex injury in the mouse. Neuroscience 2000 0.77
47 Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death. J Neurosci 2004 0.77
48 Isolation and expression of multiple forms of beta amyloid protein precursor cDNAs. Prog Clin Biol Res 1989 0.76
49 [Potential role of presenilin 1 in regulation of synaptic function]. Tsitologiia 2011 0.75
50 [Familial Alzheimer's disease mutations in the presenilin 1 gene reduce cell-cell adhesion in transfected fibroblasts]. Biofizika 2010 0.75
51 [Expression of presenilin 1 on the cell surface in motile polarized cells]. Biofizika 2006 0.75
52 Isolation of a cDNA clone for the alpha subunit of the human GABA-A receptor. Biochem Biophys Res Commun 1988 0.75
53 [Degeneration of growth cones in a culture of embryonic neurons of mouse with presenilin 1 gene knockout]. Biofizika 2009 0.75
54 Altered genetic response to beta-adrenergic receptor activation in late passage C6 glioma cells. J Neurosci Res 1992 0.75