Effects of low-level dietary deoxynivalenol on haematological and clinical parameters of the pig.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMID 8087437)

Published in Nat Toxins on January 01, 1994

Authors

D B Prelusky1, R G Gerdes, K L Underhill, B A Rotter, P Y Jui, H L Trenholm

Author Affiliations

1: Centre for Food and Animal Research, Agriculture and Agrifood Canada, Ottawa.

Articles citing this

Mechanisms of deoxynivalenol-induced gene expression and apoptosis. Food Addit Contam Part A Chem Anal Control Expo Risk Assess (2008) 1.19

Impact of deoxynivalenol on the intestinal microflora of pigs. Int J Mol Sci (2008) 0.98

The impact of the Fusarium mycotoxin deoxynivalenol on the health and performance of broiler chickens. Int J Mol Sci (2011) 0.89

Effects of dietary arginine and glutamine on alleviating the impairment induced by deoxynivalenol stress and immune relevant cytokines in growing pigs. PLoS One (2013) 0.88

Deoxynivalenol in the gastrointestinal tract of immature gilts under per os toxin application. Toxins (Basel) (2014) 0.80

Growth performance, serum biochemical profile, jejunal morphology, and the expression of nutrients transporter genes in deoxynivalenol (DON)- challenged growing pigs. BMC Vet Res (2015) 0.80

Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets. J Vet Sci (2010) 0.78

Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network. Toxins (Basel) (2016) 0.77

The fate and tissue disposition of deoxynivalenol in broiler chickens. J Vet Med Sci (2015) 0.77

An NMR-based metabolomic approach to investigate the effects of supplementation with glutamic acid in piglets challenged with deoxynivalenol. PLoS One (2014) 0.77

Effects of Feeding Barley Naturally Contaminated with Fusarium Mycotoxins on Growth Performance, Nutrient Digestibility, and Blood Chemistry of Gilts and Growth Recoveries by Feeding a Non-contaminated Diet. Asian-Australas J Anim Sci (2015) 0.76

Deoxynivalenol and its metabolite deepoxy-deoxynivalenol: multi-parameter analysis for the evaluation of cytotoxicity and cellular effects. Mycotoxin Res (2016) 0.75

Does Dietary Deoxynivalenol Modulate the Acute Phase Reaction in Endotoxaemic Pigs?-Lessons from Clinical Signs, White Blood Cell Counts, and TNF-Alpha. Toxins (Basel) (2015) 0.75

Haematological, clinical-chemical and immunological consequences of feeding Fusarium toxin contaminated diets to early lactating dairy cows. Mycotoxin Res (2016) 0.75

Articles by these authors

Two systems for the uptake of phosphate in Escherichia coli. J Bacteriol (1977) 3.46

The relationship between the phosphate-binding protein and a regulator gene product from Escherichia coli. Biochim Biophys Acta (1974) 2.18

Recent trends in glutathione biochemistry--glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation? Biochem Biophys Res Commun (1998) 1.81

Energy coupling to the transport of inorganic phosphate in Escherichia coli K12. Biochem J (1979) 1.48

Restoration of phosphate transport by the phosphate-binding protein in spheroplasts of Escherichia coli. J Bacteriol (1977) 1.44

Pharmacokinetic fate of 14C-labeled deoxynivalenol in swine. Fundam Appl Toxicol (1988) 1.16

Nontransmission of deoxynivalenol (vomitoxin) to eggs and meat in chickens fed deoxynivalenol-contaminated diets. J Agric Food Chem (1984) 1.09

The efficacy of various classes of anti-emetics in preventing deoxynivalenol-induced vomiting in swine. Nat Toxins (1993) 1.05

Further studies on the acute toxicity of ethanol in young and old rats: relative importance of pulmonary excretion and total body water. Toxicol Appl Pharmacol (1971) 1.03

Co-regulation of the phosphate-binding protein and alkaline phosphatase synthesis in Escherichia coli. J Bacteriol (1976) 1.02

Rumen ciliate protozoa: effects on digestion in the stomach of sheep. J Dairy Sci (1983) 0.98

Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine. Fundam Appl Toxicol (1994) 0.97

Plasma pharmacokinetics of the mycotoxin deoxynivalenol following oral and intravenous administration to sheep. J Environ Sci Health B (1985) 0.93

The gas chromatographic estimation of ethanol, acetaldehyde, and acetone in ethanol metabolism studies. Clin Toxicol (1971) 0.92

Binding of tellurium to hepatocellular selenoproteins during incubation with inorganic tellurite: consequences for the activity of selenium-dependent glutathione peroxidase. Int J Biochem Cell Biol (1999) 0.92

Metabolic fate and elimination in milk, urine and bile of deoxynivalenol following administration to lactating sheep. J Environ Sci Health B (1987) 0.92

Rapid, sensitive liquid chromatographic method for determination of zearalenone and alpha- and beta-zearalenol in wheat. J Assoc Off Anal Chem (1985) 0.91

Biliary excretion and enterohepatic cycling of zearalenone in immature pigs. Toxicol Appl Pharmacol (1993) 0.91

Feeding trials with vomitoxin (deoxynivalenol)-contaminated wheat: effects on swine, poultry, and dairy cattle. J Am Vet Med Assoc (1984) 0.90

Effectiveness of cholestyramine in the detoxification of zearalenone as determined in mice. Bull Environ Contam Toxicol (1995) 0.89

Injury to hepatocytes induced by a peptide toxin from the cyanobacterium Microcystis aeruginosa. Toxicon (1987) 0.89

Effect of enzyme supplementation on the nutritional value of raw, autoclaved, and dehulled lupins (Lupinus albus) in chicken diets. Poult Sci (1993) 0.87

Tissue distribution and excretion of radioactivity following administration of 14C-labeled deoxynivalenol to White Leghorn hens. Fundam Appl Toxicol (1986) 0.87

Survey of vomitoxin contamination of 1980 Ontario white winter wheat crop: results of survey and feeding trials. J Assoc Off Anal Chem (1983) 0.87

Economic losses and decontamination. Nat Toxins (1995) 0.85

Distribution of deoxynivalenol in cerebral spinal fluid following administration to swine and sheep. J Environ Sci Health B (1990) 0.83

Pharmacokinetic fate of 14C-labelled fumonisin B1 in swine. Nat Toxins (1994) 0.83

Distribution of the trichothecene mycotoxin deoxynivalenol (vomitoxin) during the milling of naturally contaminated hard red spring wheat and its fate in baked products. Food Addit Contam (1985) 0.82

Assessment of extraction procedures in the analysis of naturally contaminated grain products for deoxynivalenol (vomitoxin). J Assoc Off Anal Chem (1985) 0.82

Synthesis and degradation of aflatoxins by Aspergillus parasiticus. II. Comparative toxicity and mutagenicity of aflatoxin B1 and its autolytic breakdown products. Aust J Biol Sci (1984) 0.82

The effect of enzyme supplementation on the apparent metabolizable energy and nutrient digestibilities of wheat, barley, oats, and rye for the young broiler chick. Poult Sci (1992) 0.82

Effect of deoxynivalenol on neurotransmitters in discrete regions of swine brain. Arch Environ Contam Toxicol (1992) 0.82

Influence of level of deoxynivalenol in the diet of dairy cows on feed intake, milk production, and its composition. J Dairy Sci (1993) 0.81

Response of growing swine to dietary exposure to pure fumonisin B1 during an eight-week period: growth and clinical parameters. Nat Toxins (1996) 0.81

The uptake of the cyanobacterial hepatotoxin microcystin by isolated rat hepatocytes. Toxicon (1991) 0.81

Effect of ethanol of the fate of pentobarbital in the rat. Biochem Pharmacol (1972) 0.81

Growth, lipid metabolism and pathology of two strains of rats fed high fat diets. J Nutr (1979) 0.81

A practical guide to the prevention of Fusarium mycotoxins in grain and animal feedstuffs. Arch Environ Contam Toxicol (1989) 0.81

Investigations in the use of mice exposed to mycotoxins as a model for growing pigs. J Toxicol Environ Health (1992) 0.80

Effect of the appetite stimulant cyproheptadine on deoxynivalenol-induced reductions in feed consumption and weight gain in the mouse. J Environ Sci Health B (1997) 0.80

Increased ethanol toxicity in old rats: changes in LD50, in vivo and in vitro metabolism, and liver alcohol dehydrogenase activity. Toxicol Appl Pharmacol (1970) 0.79

Excretion profiles of the mycotoxin deoxynivalenol, following oral and intravenous administration to sheep. Fundam Appl Toxicol (1986) 0.79

The effects of acetylation upon the activity of trypsin toward ester and amide substrates. Biochemistry (1969) 0.79

The effect of acute administration of the mycotoxin zearalenone to female pigs. J Environ Sci Health B (1981) 0.78

Pharmacokinetic fate and pathological effects of 14C-fumonisin B1 in laying hens. Nat Toxins (1994) 0.78

Minimal transmission of zearalenone to milk of dairy cows. J Environ Sci Health B (1990) 0.78

Sensitive analysis of the mycotoxin zearalenone and its metabolites in biological fluids by high-performance liquid chromatography alpha. J Chromatogr (1989) 0.78

Disposition of 14C-derived residues in tissues of pigs fed radiolabelled fumonisin B1. Food Addit Contam (1997) 0.77

The metabolic significance of pentose cycle measurements in perfused liver. Biochem Int (1986) 0.77

Ingestion of vomitoxin (deoxynivalenol)-contaminated wheat by nonlactating dairy cows. J Dairy Sci (1985) 0.76

Features of microsomal and cytosolic glutathione conjugation of hexachlorobutadiene in rat liver. Chem Biol Interact (1988) 0.76

Pilot study on the plasma pharmacokinetics of fumonisin B1 in cows following a single dose by oral gavage or intravenous administration. Nat Toxins (1995) 0.76

Transmission of residues to eggs following long-term administration of 14C-labelled deoxynivalenol to laying hens. Poult Sci (1989) 0.76

Nontransmission of deoxynivalenol (vomitoxin) to milk following oral administration to dairy cows. J Environ Sci Health B (1984) 0.76

Reduction of myocardial necrosis in male albino rats by manipulation of dietary fatty acid levels. Lipids (1982) 0.76

Biological fate of fumonisin B1 in food-producing animals. Adv Exp Med Biol (1996) 0.75

Determination of fumonisins in milk. J Environ Sci Health B (1994) 0.75

Toxicity of ethanol-barbiturate mixtures. J Pharm Pharmacol (1969) 0.75

The effects of enzyme supplementation on the nutritive value of rye grain (Secale cereale) for the young broiler chick. Poult Sci (1991) 0.75

The development of a systematic method for toxicological research using an integrated multidisciplinary approach. Clin Toxicol (1971) 0.75

Two-way selection on pupal weight with different degrees of inbreeding in Tribolium castaneum. Can J Genet Cytol (1974) 0.75

Optimization of chick embryotoxicity bioassay for testing toxicity potential of fungal metabolites. J Assoc Off Anal Chem (1988) 0.75

The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells. Arch Biochem Biophys (1986) 0.75

Evaluation of potential interactions involving trichothecene mycotoxins using the chick embryotoxicity bioassay. Arch Environ Contam Toxicol (1991) 0.75

Deltamethrin residues in milk and tissues of lactating dairy cows. J Environ Sci Health B (1992) 0.75

High performance liquid chromatographic method using fluorescence detention for quantitative analysis of zearalenone and alpha-zearalenol in blood plasma. J Assoc Off Anal Chem (1981) 0.75

Some effects of ethanol on the toxicity and distribution of barbiturates in rats. Can J Physiol Pharmacol (1970) 0.75

Effects of feeding white Leghorn hens diets that contain deoxynivalenol (vomitoxin)-contaminated wheat. Poult Sci (1985) 0.75

Gas chromatographic detection of the mycotoxin zearalenone in blood serum. J Assoc Off Anal Chem (1980) 0.75

Biochemical aspects of the interaction of ethanol with barbiturates. Can J Biochem (1970) 0.75

The tolerance of White Leghorn and broiler chicks, and turkey poults to diets that contained deoxynivalenol (vomitoxin)-contaminated wheat. Poult Sci (1985) 0.75

The effect of ethanol on phenobarbitone and pentobarbitone absorption into rat blood and brain. J Pharm Pharmacol (1971) 0.75

Partial hepatectomy and liver regeneration in the rabbit. Cytobios (1971) 0.75

Toxicity of ethanol barbiturate mixtures. J Pharm Pharmacol (1970) 0.75

Methyl mercury: acute toxicity, tissue distribution and decay profiles in the guinea pig. Toxicol Appl Pharmacol (1973) 0.75

Liver lipid levels in White Leghorn hens fed diets that contained wheat contaminated by deoxynivalenol (vomitoxin). Poult Sci (1983) 0.75

The formation of both a mono- and a bis-substituted glutathione conjugate of hexachlorobutadiene by isolated hepatocytes and following in vivo administration to the rat. Chem Biol Interact (1985) 0.75

Accumulation and tissue distribution of mercury in the guinea pig during subacute administration of methyl mercury. Toxicol Appl Pharmacol (1974) 0.75