Published in Circulation on January 01, 1993
Atrial natriuretic peptide promotes cardiomyocyte survival by cGMP-dependent nuclear accumulation of zyxin and Akt. J Clin Invest (2005) 1.70
Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics. Pharmacol Ther (2009) 1.66
Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene. J Clin Invest (1994) 1.60
Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A (2006) 1.48
Emerging Roles of Natriuretic Peptides and their Receptors in Pathophysiology of Hypertension and Cardiovascular Regulation. J Am Soc Hypertens (2010) 1.05
A functional role for endogenous atrial natriuretic peptide in a canine model of early left ventricular dysfunction. J Clin Invest (1995) 1.02
Obesity and natriuretic peptides, BNP and NT-proBNP: mechanisms and diagnostic implications for heart failure. Int J Cardiol (2014) 0.94
Guanylyl cyclase / atrial natriuretic peptide receptor-A: role in the pathophysiology of cardiovascular regulation. Can J Physiol Pharmacol (2011) 0.90
The functional genomics of guanylyl cyclase/natriuretic peptide receptor-A: perspectives and paradigms. FEBS J (2011) 0.90
Prolonged atrial natriuretic peptide exposure stimulates guanylyl cyclase-a degradation. Endocrinology (2010) 0.88
Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo. Br J Pharmacol (2006) 0.85
Natriuretic peptides and cyclic guanosine 3',5'-monophosphate in asymptomatic and symptomatic left ventricular dysfunction. Heart (1996) 0.84
Atrial natriuretic peptide affects cardiac remodeling, function, heart failure, and survival in a mouse model of dilated cardiomyopathy. Hypertension (2013) 0.81
Abnormal vascular responses in human chronic cardiac failure are both endothelium dependent and endothelium independent. Heart (1998) 0.81
Ergometric exercise testing and sensitivity of cyclic guanosine 3',5'-monophosphate (cGMP) in diagnosing asymptomatic left ventricular dysfunction. Br Heart J (1995) 0.81
The cyclic guanosine monophosphate/B-type natriuretic peptide ratio and mortality in advanced heart failure. Eur J Heart Fail (2009) 0.78
Neuroendocrine changes in chronic cardiac failure. Basic Res Cardiol (1996) 0.76
Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte. J Mol Cell Cardiol (2011) 0.76
Activation of the neuroendocrine response in heart failure: adaptive or maladaptive process? Cardiovasc Drugs Ther (1996) 0.75
Possibility of downregulation of atrial natriuretic peptide receptor coupled to guanylate cyclase in peripheral vascular beds of patients with chronic severe heart failure. Circulation (1993) 0.75
Silent disease progression in clinically stable heart failure. Eur J Heart Fail (2016) 0.75
Vasodilator therapy with hydralazine induces angiotensin AT receptor-mediated cardiomyocyte growth in mice lacking guanylyl cyclase-A. Br J Pharmacol (2010) 0.75
New Drugs You Are Going to Read About: Serelaxin, Ularitide, TRV027. Curr Emerg Hosp Med Rep (2015) 0.75
Is neurohormonal activation a major determinant of the response to ACE inhibition in left ventricular dysfunction and heart failure? Br Heart J (1994) 0.75
Chronic heart failure as a state of reduced effectiveness of the natriuretic peptide system: implications for therapy. Eur J Heart Fail (2016) 0.75
Prostanoid receptors: structures, properties, and functions. Physiol Rev (1999) 8.60
A ras-related gene with transformation suppressor activity. Cell (1989) 5.81
X-ray diffraction evidence for the extensibility of actin and myosin filaments during muscle contraction. Biophys J (1994) 4.37
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme. Genes Dev (1994) 4.19
Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol. Proc Natl Acad Sci U S A (1984) 3.84
Prostaglandin D2 as a mediator of allergic asthma. Science (2000) 3.19
Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature (1997) 3.07
Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. Nat Med (2001) 2.98
Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity. Nature (1993) 2.91
Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3. Nature (1998) 2.88
Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction. Am Heart J (1998) 2.51
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol (1997) 2.44
alpha-Galactosidase A deficient mice: a model of Fabry disease. Proc Natl Acad Sci U S A (1997) 2.43
A detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolution. Genetics (2000) 2.19
Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2). Proc Natl Acad Sci U S A (1999) 2.15
Erythromycin reduces neutrophils and neutrophil-derived elastolytic-like activity in the lower respiratory tract of bronchiolitis patients. Am Rev Respir Dis (1992) 2.12
The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs. Endocrinology (2000) 2.08
VIPP1, a nuclear gene of Arabidopsis thaliana essential for thylakoid membrane formation. Proc Natl Acad Sci U S A (2001) 2.07
Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice. Biochem Biophys Res Commun (1998) 2.04
Activation of the beta-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations. Cancer Res (1998) 2.02
Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies. Leukemia (2010) 2.01
Quantitative measurements of cardiac phosphorus metabolites in coronary artery disease by 31P magnetic resonance spectroscopy. Circulation (1995) 1.97
Long-term nitrate use may be deleterious in ischemic heart disease: A study using the databases from two large-scale postinfarction studies. Multicenter Myocardial Ischemia Research Group. Am Heart J (1999) 1.94
Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failure. J Am Coll Cardiol (2001) 1.87
A medium-density genetic linkage map of the bovine genome. Mamm Genome (1997) 1.85
Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies. Leukemia (2013) 1.84
Small-angle synchrotron x-ray scattering reveals distinct shape changes of the myosin head during hydrolysis of ATP. Science (1992) 1.82
Real-time automated PCR for early diagnosis and monitoring of cytomegalovirus infection after bone marrow transplantation. J Clin Microbiol (2000) 1.80
Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.79
Borg proteins control septin organization and are negatively regulated by Cdc42. Nat Cell Biol (2001) 1.76
Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure. J Am Coll Cardiol (1998) 1.75
Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor. J Biol Chem (1993) 1.72
Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes. Proc Natl Acad Sci U S A (1989) 1.69
High levels of plasma brain natriuretic peptide and interleukin-6 after optimized treatment for heart failure are independent risk factors for morbidity and mortality in patients with congestive heart failure. J Am Coll Cardiol (2000) 1.64
cDNA cloning, expression analysis, and mapping of the mouse Nedd4 gene. Genomics (1997) 1.64
Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype. J Biol Chem (1993) 1.61
Molecular mechanisms of diverse actions of prostanoid receptors. Biochim Biophys Acta (1995) 1.60
Mapping of quantitative trait loci controlling trypanotolerance in a cross of tolerant West African N'Dama and susceptible East African Boran cattle. Proc Natl Acad Sci U S A (2003) 1.60
Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists. Biochem Pharmacol (2001) 1.56
The see-through medaka: a fish model that is transparent throughout life. Proc Natl Acad Sci U S A (2001) 1.54
cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla. J Biol Chem (1994) 1.53
Mechanism of reversion of Rous sarcoma virus transformation by herbimycin A: reduction of total phosphotyrosine levels due to reduced kinase activity and increased turnover of p60v-src1. Cancer Res (1989) 1.51
Impaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout mice. J Biol Chem (2000) 1.51
Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans. J Biochem (1999) 1.50
Establishment of medaka (Oryzias latipes) transgenic lines with the expression of green fluorescent protein fluorescence exclusively in germ cells: a useful model to monitor germ cells in a live vertebrate. Proc Natl Acad Sci U S A (2001) 1.48
Role of the rasGAP-associated docking protein p62(dok) in negative regulation of B cell receptor-mediated signaling. Genes Dev (2000) 1.48
Long-term beneficial effect of late reperfusion for acute anterior myocardial infarction with percutaneous transluminal coronary angioplasty. Circulation (1998) 1.47
Basic fibroblast growth factor has neuroprotective effects on axotomy-induced spinal motoneuron death and wobbler mouse motoneuron disease. Muscle Nerve (1996) 1.46
Significance of the expression of proliferation-associated nucleolar antigen p120 in human colorectal tumors. Hum Pathol (1997) 1.45
Retracted Dominant-negative effects of a novel mutation in the filamin myopathy. Neurology (2010) 1.42
Relationship between transcardiac gradient of endothelin-1 and left ventricular remodelling in patients with first anterior myocardial infarction. Eur Heart J (2003) 1.41
A novel mutation in the vasopressin V2 receptor gene in a woman with congenital nephrogenic diabetes insipidus. Intern Med (1999) 1.40
Septal perfusion and wall thickening in patients with left bundle branch block assessed by technetium-99m-sestamibi gated tomography. J Nucl Med (1997) 1.40
Vesicular prurigo pigmentosa cured by minocycline. J Eur Acad Dermatol Venereol (2001) 1.40
Clinical significance of small ventricles. Neurology (1991) 1.40
Myocardial metabolic abnormalities in hypertrophic cardiomyopathy assessed by iodine-123-labeled beta-methyl-branched fatty acid myocardial scintigraphy and its relation to exercise-induced ischemia. Jpn Circ J (1998) 1.39
Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development. Gut (2004) 1.39
Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells. J Biol Chem (1994) 1.38
Failure of L-arginine to induce hypotension in patients with a history of accelerated-malignant hypertension. J Hum Hypertens (2000) 1.38
Tyrosines 1148 and 1173 of activated human epidermal growth factor receptors are binding sites of Shc in intact cells. J Biol Chem (1994) 1.37
Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas. Biochem Biophys Res Commun (1994) 1.34
Identification of septins in neurofibrillary tangles in Alzheimer's disease. Am J Pathol (1998) 1.34
Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase. Eur J Biochem (1993) 1.33
In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs. Br J Pharmacol (1995) 1.33
Determination by PCR-RFLP of apo E genotype in a Japanese population. J Lab Clin Med (1993) 1.32
Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin. Cancer Res (1991) 1.30
Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype. J Biol Chem (1993) 1.29
A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity. Oncogene (2000) 1.26
Antitumor activity of a novel podophyllotoxin derivative (TOP-53) against lung cancer and lung metastatic cancer. Cancer Res (1996) 1.25
Differential localization of septins in the mouse brain. J Comp Neurol (2000) 1.24
Glutamine synthetase from rice plant roots. Arch Biochem Biophys (1972) 1.22
Chronic cerebral hypoperfusion induces white matter lesions and loss of oligodendroglia with DNA fragmentation in the rat. Acta Neuropathol (2003) 1.22
Phosphatidylinositol kinase activities in normal and Rous sarcoma virus-transformed cells. Mol Cell Biol (1985) 1.21
Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms. J Biol Chem (1998) 1.21
Inhibition of metastin (kisspeptin-54)-GPR54 signaling in the arcuate nucleus-median eminence region during lactation in rats. Endocrinology (2007) 1.20
Two isoforms of prostaglandin E receptor EP3 subtype. Different COOH-terminal domains determine sensitivity to agonist-induced desensitization. J Biol Chem (1993) 1.19
Mutations of p53 and K-ras genes as prognostic factors for non-small cell lung cancer. Int J Oncol (1998) 1.19
Serum concentrations of myoglobin vs human heart-type cytoplasmic fatty acid-binding protein in early detection of acute myocardial infarction. Clin Chem (1997) 1.19
Analysis of negatively charged dye-binding antibodies reactive with double-stranded DNA and heparan sulfate in serum from patients with rheumatic diseases. Clin Exp Immunol (1988) 1.19
Interaction of Shc with adaptor protein adaptins. J Biol Chem (1996) 1.18
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection. J Clin Invest (2001) 1.18
Identification of a key amino acid of the beta2-adrenergic receptor for high affinity binding of salmeterol. Mol Pharmacol (1998) 1.17
Studies on metabolic role of 5'-Methylthioadenosine in Ochromonas malhamensis and other microorganisms. Arch Microbiol (1976) 1.16
Genome-wide linkage disequilibrium in two Japanese beef cattle breeds. Anim Genet (2006) 1.16
The mouse prostaglandin E receptor EP2 subtype: cloning, expression, and northern blot analysis. FEBS Lett (1995) 1.16
Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance. Cancer Res (1990) 1.15
Familial idiopathic brain calcification with autosomal dominant inheritance. Neurology (1997) 1.15
Cellular localization of mRNAs for prostaglandin E receptor subtypes in mouse gastrointestinal tract. Am J Physiol (1997) 1.14
Prostaglandin F2alpha-induced expression of 20alpha-hydroxysteroid dehydrogenase involves the transcription factor NUR77. J Biol Chem (2000) 1.14
Intravenous atrial natriuretic peptide prevents left ventricular remodeling in patients with first anterior acute myocardial infarction. J Am Coll Cardiol (2001) 1.14
Characterization of the LPS-stimulated expression of EP2 and EP4 prostaglandin E receptors in mouse macrophage-like cell line, J774.1. Biochem Biophys Res Commun (1998) 1.14
Inhibition of cell attachment, invasion and metastasis of human carcinoma cells by anti-integrin beta 1 subunit antibody. Jpn J Cancer Res (1992) 1.13
Quantitative trait loci analysis for growth and carcass traits in a Meishan x Duroc F2 resource population. J Anim Sci (2003) 1.13
Genetic structure, isolation and characterization of a Bacillus licheniformis cell wall hydrolase. Mol Gen Genet (1992) 1.13
Detection of three genetic polymorphisms in the 5'-flanking region and intron 1 of human CYP1A2 in the Japanese population. Jpn J Cancer Res (1999) 1.13
Antibody production in vitamin A-depleted rats is impaired after immunization with bacterial polysaccharide or protein antigens. FASEB J (1990) 1.13