Published in Blood on August 01, 1993
The molecular basis of β-thalassemia. Cold Spring Harb Perspect Med (2013) 1.08
A normal beta-globin allele as a modifier gene ameliorating the severity of alpha-thalassemia in mice. Proc Natl Acad Sci U S A (1999) 0.78
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. Proc Natl Acad Sci U S A (1997) 4.38
A major positive regulatory region located far upstream of the human alpha-globin gene locus. Genes Dev (1990) 3.31
Delta-beta-thalassemia is due to a gene deletion. Cell (1976) 2.12
F-cells in the adult: normal values and levels in individuals with hereditary and acquired elevations of Hb F. Blood (1975) 2.06
Fetal haemoglobin production and the sickle gene in the oases of Eastern Saudi Arabia. Br J Haematol (1978) 1.98
The anaemia of P. falciparum malaria. Br J Haematol (1980) 1.97
Characterization of the major regulatory element upstream of the human alpha-globin gene cluster. Mol Cell Biol (1991) 1.97
Membrane cholesterol dynamics: cholesterol domains and kinetic pools. Proc Soc Exp Biol Med (1991) 1.82
Healing of broken human chromosomes by the addition of telomeric repeats. Am J Hum Genet (1994) 1.69
A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype. Hum Mol Genet (2000) 1.58
Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster. Proc Natl Acad Sci U S A (2001) 1.57
Oral iodized oil for correcting iodine deficiency: optimal dosing and outcome indicator selection. J Clin Endocrinol Metab (1994) 1.52
De novo truncation of chromosome 16p and healing with (TTAGGG)n in the alpha-thalassemia/mental retardation syndrome (ATR-16). Am J Hum Genet (1993) 1.46
Molecular basis for dominantly inherited inclusion body beta-thalassemia. Proc Natl Acad Sci U S A (1990) 1.42
Glomerular proteinuria as an early sign of renal-transplant rejection. Clin Nephrol (1991) 1.39
[Tumor marker determination errors]. Dtsch Med Wochenschr (2002) 1.39
Defective synthesis of HbE is due to reduced levels of beta E mRNA. Nature (1980) 1.38
A congenital dyserythropoietic anaemia variant presenting as hydrops fetalis. Br J Haematol (1989) 1.38
A new form of hereditary persistence of fetal hemoglobin in blacks and its association with sickle cell trait. Blood (1975) 1.36
Effects of beta adrenergic blockade on plasma catecholamines in exercise. Nature (1974) 1.35
Pattern of maternal F-cell production during pregnancy. Lancet (1977) 1.32
Comparison of adrenergic beta-blocking drugs in angina pectoris. Br Med J (1971) 1.32
A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice. Mol Cell Biol (1992) 1.29
Beta + thalassemia--Portuguese type: clinical, haematological and molecular studies of a newly defined form of beta thalassaemia. Br J Haematol (1983) 1.29
Post-natal decline of fetal haemoglobin in homozygous sickle cell disease: relationship to parenteral Hb F levels. Br J Haematol (1982) 1.29
Plasma uptake of dopamine and 5-hydroxytryptamine and plasma-catecholamine levels in patients with Huntington's chorea. Lancet (1974) 1.27
Mitochondria and sarcoplasmic reticulum function in cardiac hypertrophy and failure. Am J Physiol (1973) 1.26
Analysis of the human alpha-globin gene cluster in transgenic mice. Proc Natl Acad Sci U S A (1993) 1.25
Control of haemoglobin switching by a developmental clock? Nature (1985) 1.25
A form of hereditary persistence of fetal haemoglobin characterized by uneven cellular distribution of haemoglobin F and the production of haemoglobins A and A2 in homozygotes. Br J Haematol (1975) 1.24
Haemoglobin synthesis during human fetal development. Br Med Bull (1976) 1.23
Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments. EMBO J (1995) 1.23
Understanding alpha globin gene expression: a step towards effective gene therapy. Semin Hematol (1998) 1.22
A model for the persistence or reactivation of fetal haemoglobin production. Lancet (1976) 1.21
Haemoglobin synthesis during human foetal development. Nature (1973) 1.20
Cholesterol domains in biological membranes. Mol Membr Biol (1995) 1.20
Transmembrane distribution of sterol in the human erythrocyte. Biochim Biophys Acta (1991) 1.20
Analysis of an inversion within the human beta globin gene cluster. Nucleic Acids Res (1985) 1.18
Genetic control of F cells in human adults. Blood (1979) 1.16
Characterization of beta-globin mRNA in the beta0 thalassemias. Cell (1978) 1.16
T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia. Blood (1986) 1.15
Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells. Hum Exp Toxicol (2009) 1.13
Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease. Behav Brain Res (2011) 1.12
Observations on the incidence and cause of macrocytosis in patients on azathioprine therapy following renal transplantation. Transplantation (1974) 1.12
Analysis of a 70 kb segment of DNA containing the human zeta and alpha-globin genes linked to their regulatory element (HS-40) in transgenic mice. Nucleic Acids Res (1994) 1.12
Recent advances in membrane cholesterol domain dynamics and intracellular cholesterol trafficking. Proc Soc Exp Biol Med (1996) 1.12
alpha-thalassemia resulting from a negative chromosomal position effect. Blood (2000) 1.11
Relapsing polychondritis with glomerulonephritis. Improvement with prednisone and cyclophosphamide. JAMA (1981) 1.10
Thalassaemia intermedia in Cyprus: the interaction of alpha and beta thalassaemia. Br J Haematol (1983) 1.10
Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice. EMBO J (1992) 1.09
Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster. Blood (1990) 1.09
Interaction of heterocellular hereditary persistence of foetal haemoglobin with beta thalassaemia and sickle cell anaemia. Nature (1976) 1.09
Intestinal vascular malformations. Surgery (1979) 1.08
Lipid binding to amyloid beta-peptide aggregates: preferential binding of cholesterol as compared with phosphatidylcholine and fatty acids. J Neurochem (1997) 1.08
The bone marrow in human cerebral malaria: parasite sequestration within sinusoids. Br J Haematol (1987) 1.08
Inheritance of F cell frequency in heterocellular hereditary persistence of fetal hemoglobin: an example of allelic exclusion. Am J Hum Genet (1977) 1.06
Linkage analysis of nondeletion hereditary persistence of fetal hemoglobin. Science (1982) 1.06
Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice. J Neurochem (1996) 1.05
Heterocellular hereditary persistence of fetal haemoglobin (heterocellular HPFH) and its interaction with beta thalassaemia. Br J Haematol (1977) 1.05
The heterogeneity of normal Hb A2-beta thalassaemia in Greece. Br J Haematol (1979) 1.05
Assessment of the value of a competitive protein binding radioassay of folic acid in the detection of folic acid deficiency. J Clin Pathol (1984) 1.05
Natural history of congenital dyserythropoietic anemia type II. Blood (2001) 1.04
The interaction of alpha thalassaemia with heterozygous beta thalassaemia. Br J Haematol (1982) 1.04
A comparison of the homozygous states for G gamma and G gamma A gamma delta beta thalassaemia. Br J Haematol (1979) 1.04
Hereditary persistence of fetal haemoglobin (HPFH) and delta beta thalassaemia. Br J Haematol (1979) 1.03
Assessment of a radioisotopic assay for vitamin B12 using an intrinsic factor preparation with R proteins blocked by vitamin B12 analogues. J Clin Pathol (1982) 1.03
A fault in the design of the deoxyuridine suppression test. Clin Lab Haematol (1979) 1.03
Distribution and fluidizing action of soluble and aggregated amyloid beta-peptide in rat synaptic plasma membranes. J Biol Chem (1999) 1.02
Beta-thalassaemia. Baillieres Clin Haematol (1998) 1.02
The patterns of fetal haemoglobin production in leukaemia. Br J Haematol (1976) 1.02
Prostaglandin E2 production in astrocytes: regulation by cytokines, extracellular ATP, and oxidative agents. Prostaglandins Leukot Essent Fatty Acids (2003) 1.01
Role of macrophages in acetaminophen (paracetamol)-induced hepatotoxicity. J Pathol (1996) 1.01
Developmental biology of human hemoglobins. Prog Hematol (1977) 1.01
Papulosis atrophicans maligna (Köhlmeier-Degos disease): a disseminated occlusive vasculopathy. Ann Neurol (1978) 1.00
Delta-beta-thalassaemia in a Chinese family. Br J Haematol (1972) 1.00
Interaction between erythroblasts and macrophages in vitro: effect of neuraminidase-treatment of erythroblasts and the role of serum factors. Br J Haematol (1983) 0.99
Sickle beta 0 thalassemia in Eastern Saudi Arabia. Am J Hum Genet (1980) 0.99
A novel form of congenital dyserythropoietic anemia associated with deficiency of erythroid CD44 and a unique blood group phenotype [In(a-b-), Co(a-b-)]. Blood (1994) 0.98
Hematologic and biosynthetic studies in homozygous hemoglobin Constant Spring. J Clin Invest (1984) 0.98
Assessment of deoxyuridine suppression test in diagnosis of vitamin B12 or folate deficiency. Br Med J (1974) 0.98
Protein synthesis in megaloblastic erythropoiesis caused by vitamin B12 deficiency. Nature (1968) 0.97
Lipid binding to sterol carrier protein-2 is inhibited by ethanol. Biochim Biophys Acta (1999) 0.97
Cytotoxic protein molecules generated as a consequence of ethanol metabolism in vitro and in vivo. Lancet (1986) 0.97
Intramedullary neurilemoma of the cervical spinal cord. Case report. J Neurosurg (1975) 0.96
Sequential analysis of urinary enzymes in early diagnosis of parenchymal damage after renal homotransplantation. Br Med J (1968) 0.96
Restriction endonuclease maps of the beta-like globin gene cluster in the British and Greek forms of HPFH, and for one example of G gamma beta + HPFH. Br J Haematol (1982) 0.96
Hb F synthesis in sickle cell anaemia: a comparison of Saudi Arab cases with those of African origin. Br J Haematol (1980) 0.96
Occurrence of G gamma Hb F in Greek HPFH: analysis of heterozygotes and compound heterozygotes with beta thalassaemia. Br J Haematol (1979) 0.96
Understanding erythroid differentiation. Curr Biol (1993) 0.96
Thiamine responsive anaemia: a study of two further cases. Br J Haematol (1982) 0.96
Results of three years' experience with the deoxyuridine suppression test. Acta Haematol (1977) 0.96
The effect of aging and dietary restriction on DNA repair. Exp Cell Res (1989) 0.96
Goitre epidemiology: thyroid volume, iodine excretion, thyroglobulin and thyrotropin in Germany and Sweden. Acta Endocrinol (Copenh) (1986) 0.95
Impaired protein synthesis in erythroblasts enhances their phagocytosis by macrophages. Br J Haematol (1983) 0.95
Intravascular haemolysis and increased prevalence of myeloma and monoclonal gammopathy in congenital dyserythropoietic anaemia, type III. Eur J Haematol (1994) 0.95
Observations on the ultrastructure of erythropoietic cells and reticulum cells in the bone marrow of patients with homozygous beta-thalassaemia. Br J Haematol (1975) 0.95
P2Y2 nucleotide receptor-mediated responses in brain cells. Mol Neurobiol (2010) 0.94