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Top papers

Rank Title Journal Year PubWeight™‹?›
1 N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state. J Virol 1991 3.55
2 Natural infection of Suffolk sheep with scrapie virus. J Infect Dis 1982 3.42
3 Characterization of scrapie infection in mouse neuroblastoma cells. J Gen Virol 1987 2.54
4 Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells. J Virol 1989 2.08
5 Characterization of Aleutian disease virus as a parvovirus. J Virol 1980 2.04
6 Identification of a nonvirion protein of Aleutian disease virus: mink with Aleutian disease have antibody to both virion and nonvirion proteins. J Virol 1982 2.02
7 Potent inhibition of scrapie-associated PrP accumulation by congo red. J Neurochem 1992 2.00
8 Aleutian disease of mink: the antibody response of sapphire and pastel mink to Aleutian disease virus. J Immunol 1975 1.95
9 Virologic and neurohistologic findings in dairy goats affected with natural scrapie. Vet Pathol 1980 1.88
10 Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells. J Virol 1994 1.85
11 Comparative pathogenicity of four strains of Aleutian disease virus for pastel and sapphire mink. Infect Immun 1983 1.77
12 Congo red inhibition of scrapie agent replication. J Virol 1993 1.60
13 In situ molecular hybridization for detection of Aleutian mink disease parvovirus DNA by using strand-specific probes: identification of target cells for viral replication in cell cultures and in mink kits with virus-induced interstitial pneumonia. J Virol 1987 1.56
14 Partial purification and evidence for multiple molecular forms of the scrapie agent. Biochemistry 1978 1.42
15 Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie. EMBO J 1997 1.36
16 Intracerebral transmission of scrapie to cattle. J Infect Dis 1994 1.36
17 Passive transfer of antiviral antibodies restricts replication of Aleutian mink disease parvovirus in vivo. J Virol 1989 1.32
18 Analysis of Aleutian disease of mink parvovirus infection using strand-specific hybridization probes. Intervirology 1987 1.29
19 Detection of prion protein mRNA in normal and scrapie-infected tissues and cell lines. J Gen Virol 1988 1.28
20 Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells. J Virol 1990 1.24
21 Analysis of Aleutian disease virus infection in vitro and in vivo: demonstration of Aleutian disease virus DNA in tissues of infected mink. J Virol 1985 1.21
22 Immunohistochemical detection of prion protein in sheep with scrapie. J Vet Diagn Invest 1993 1.20
23 Comparative analysis of scrapie agent inactivation methods. J Virol Methods 1993 1.18
24 Monoclonal antibodies against Aleutian disease virus distinguish virus strains and differentiate sites of virus replication from sites of viral antigen sequestration. J Virol 1986 1.18
25 Methods for studying prion protein (PrP) metabolism and the formation of protease-resistant PrP in cell culture and cell-free systems. An update. Mol Biotechnol 1999 1.10
26 Aleutian disease virus, a parvovirus, is proteolytically degraded during in vivo infection in mink. J Virol 1984 1.08
27 Temporal distribution of transmissible mink encephalopathy virus in mink inoculated subcutaneously. J Virol 1987 1.08
28 Detection of prion protein in formalin-fixed brain by hydrated autoclaving immunohistochemistry for the diagnosis of scrapie in sheep. J Vet Diagn Invest 1994 1.07
29 In vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain. Proc Natl Acad Sci U S A 1988 1.04
30 Demonstration of scrapie strain diversity in infected PC12 cells. J Gen Virol 1992 1.04
31 Royal pastel mink respond variously to inoculation with Aleutian disease virus of low virulence. J Virol 1984 1.04
32 Experimental scrapie in the mouse: electrophoretic and sedimentation properties of the partially purified agent. J Neurochem 1980 1.03
33 Protease sensitivity and nuclease resistance of the scrapie agent propagated in vitro in neuroblastoma cells. J Virol 1991 1.00
34 Sedimentation characteristics of the scrapie agent from murine spleen and brain. Biochemistry 1978 0.99
35 Sedimentation properties of the scrapie agent. Proc Natl Acad Sci U S A 1977 0.93
36 Experimental infection of sheep and goats with transmissible mink encephalopathy virus. Can J Vet Res 1987 0.92
37 Temporal replication of the Pullman strain of Aleutian disease virus in royal pastel mink. J Virol 1985 0.92
38 Brain tissue from persons dying of Creutzfeldt-Jakob disease causes scrapie-like encephalopathy in goats. Ann Neurol 1980 0.89
39 Demonstration of Aleutian disease virus-specific lymphocyte response in mink with progressive Aleutian disease: comparison of sapphire and pastel mink infected with different virus strains. J Immunol 1983 0.84
40 Impaired phagocytosis by the mononuclear phagocytic system in sapphire mink affected with Aleutian disease. Proc Soc Exp Biol Med 1990 0.84
41 Delayed hypersensitivity in normal and aleutian disease-affected mink. Z Immunitatsforsch Exp Klin Immunol 1974 0.82
42 Lymphoreticular proliferative disease in mink homozygous for the Aleutian gene. J Natl Cancer Inst 1972 0.81
43 Scrapie-associated PrP accumulation and its inhibition: revisiting the amyloid-glycosaminoglycan connection. Ann N Y Acad Sci 1994 0.79
44 Ontogeny of mink IgG, IgA, and IgM. Proc Soc Exp Biol Med 1978 0.79
45 Serological evidence for an inflammatory response in murine scrapie. J Infect Dis 2000 0.79
46 Experimental infection of fetal and newborn Suffolk sheep with scrapie virus. Am J Vet Res 1984 0.79
47 Evidence for hydrophobic domains on the surface of the scrapie agent. Trans Am Neurol Assoc 1978 0.78
48 The trouble with transmissible degenerative encephalopathy agents. Vet J 2000 0.75
49 Cerebrocortical degeneration in goats inoculated with mink-passaged scrapie virus. Vet Pathol 1986 0.75
50 Slow viruses: molecular properties of the agents causing scrapie in mice and hamsters. Prog Clin Biol Res 1980 0.75
51 Immunization of dogs with Q fever vaccines: comparison of phase I, II and phase I CMR Coxiella burnetii vaccines. Rev Elev Med Vet Pays Trop 1993 0.75
52 Common occurrence of urethral cysts in older female ranch mink. Vet Pathol 1981 0.75