Published in Trends Biochem Sci on January 01, 1994
Principles of protein folding--a perspective from simple exact models. Protein Sci (1995) 7.54
Understanding beta-hairpin formation. Proc Natl Acad Sci U S A (1999) 3.01
A refined solution structure of hen lysozyme determined using residual dipolar coupling data. Protein Sci (2001) 1.88
Macromolecular crowding perturbs protein refolding kinetics: implications for folding inside the cell. EMBO J (2000) 1.81
Fast folding of a prototypic polypeptide: the immunoglobulin binding domain of streptococcal protein G. Protein Sci (1994) 1.69
Protein secondary structural types are differentially coded on messenger RNA. Protein Sci (1996) 1.47
Multiple pathways on a protein-folding energy landscape: kinetic evidence. Proc Natl Acad Sci U S A (1999) 1.28
The alpha-helix folds on the millisecond time scale. Proc Natl Acad Sci U S A (1999) 1.24
A new protein folding screen: application to the ligand binding domains of a glutamate and kainate receptor and to lysozyme and carbonic anhydrase. Protein Sci (1999) 1.17
Thermally induced fibrillar aggregation of hen egg white lysozyme. Biophys J (2004) 1.12
Correct protein folding in glycerol. Proc Natl Acad Sci U S A (1997) 1.11
A unified mechanism for protein folding: predetermined pathways with optional errors. Protein Sci (2007) 1.09
Convergent chemical synthesis and high-resolution x-ray structure of human lysozyme. Proc Natl Acad Sci U S A (2007) 1.08
Kinetic evidence for an on-pathway intermediate in the folding of cytochrome c. Proc Natl Acad Sci U S A (1999) 1.06
Hsp60-independent protein folding in the matrix of yeast mitochondria. EMBO J (1996) 1.02
Comparison of the kinetics of S-S bond, secondary structure, and active site formation during refolding of reduced denatured hen egg white lysozyme. Protein Sci (1999) 1.01
Competition between folding and glycosylation in the endoplasmic reticulum. EMBO J (1996) 1.00
Dynamics of lysozyme structure network: probing the process of unfolding. Biophys J (2007) 0.97
Conformational stability of apoflavodoxin. Protein Sci (1996) 0.94
Coupling between properties of the protein shape and the rate of protein folding. PLoS One (2009) 0.93
Urea impedes the hydrophobic collapse of partially unfolded proteins. Biophys J (2009) 0.93
Neutron reflectometry studies of the adsorbed structure of the amelogenin, LRAP. J Phys Chem B (2013) 0.91
Two-phase induction of the nonnative alpha-helical form of beta-lactoglobulin in the presence of trifluoroethanol. Biophys J (1999) 0.89
Characterization of the unfolded state of bovine alpha-lactalbumin and comparison with unfolded states of homologous proteins. Protein Sci (2006) 0.89
Characterization of a partially structured state in an all-beta-sheet protein. Biochem J (1997) 0.89
Characterization of a quaternary-structured folding intermediate of an antibody Fab-fragment. Protein Sci (1995) 0.88
Kinetics of salt-dependent unfolding of [2Fe-2S] ferredoxin of Halobacterium salinarum. Extremophiles (2007) 0.87
A near-native state on the slow refolding pathway of hen lysozyme. Protein Sci (1999) 0.87
Protein folding in the endoplasmic reticulum: lessons from the human chorionic gonadotropin beta subunit. Protein Sci (1996) 0.85
The methanol-induced transition and the expanded helical conformation in hen lysozyme. Protein Sci (1998) 0.85
Synthesis, folding, and structure of the beta-turn mimic modified B1 domain of streptococcal protein G. Protein Sci (1999) 0.84
Role of individual disulfide bonds in hen lysozyme early folding steps. Protein Sci (2002) 0.82
The ribosome can prevent aggregation of partially folded protein intermediates: studies using the Escherichia coli ribosome. PLoS One (2014) 0.82
The mechanism of antiparallel β-sheet formation based on conditioned self-avoiding walk. Eur Phys J E Soft Matter (2012) 0.79
The refolding of hen egg white riboflavin-binding protein: effect of protein disulphide isomerase on the reoxidation of the reduced protein. Biochem J (1995) 0.79
Protein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitus. CNS Neurol Disord Drug Targets (2014) 0.79
The folding and assembly of the dodecameric type II dehydroquinases. Biochem J (1999) 0.78
Deciphering ligand specificity of a Clostridium thermocellum family 35 carbohydrate binding module (CtCBM35) for gluco- and galacto- substituted mannans and its calcium induced stability. PLoS One (2013) 0.78
Addressing mechanism of fibrillization/aggregation and its prevention in presence of osmolytes: spectroscopic and calorimetric approach. PLoS One (2014) 0.77
Prolonged glycation of hen egg white lysozyme generates non amyloidal structures. PLoS One (2013) 0.77
Identification of the folding inhibitors of hen-egg lysozyme: gathering the right tools. Eur Biophys J (2009) 0.76
Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. BMC Struct Biol (2007) 0.76
Reinvestigation of the oxidative folding pathways of hen egg white lysozyme: switching of the major pathways by temperature control. Int J Mol Sci (2013) 0.75
Backbone 1H, 13C, and 15N resonance assignments for lysozyme from bacteriophage lambda. Biomol NMR Assign (2010) 0.75
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis. Nature (1997) 5.47
The folding of hen lysozyme involves partially structured intermediates and multiple pathways. Nature (1992) 4.32
Structural and mechanistic basis of immunity toward endonuclease colicins. Nat Struct Biol (1999) 3.37
A gamma-ray burst at a redshift of z approximately 8.2. Nature (2009) 3.29
Detection of transient protein folding populations by mass spectrometry. Science (1993) 2.85
Responsive gels formed by the spontaneous self-assembly of peptides into polymeric beta-sheet tapes. Nature (1997) 2.69
Partially unfolded states of beta(2)-microglobulin and amyloid formation in vitro. Biochemistry (2000) 2.47
The Scottish doctor--learning outcomes for the medical undergraduate in Scotland: a foundation for competent and reflective practitioners. Med Teach (2002) 2.43
Broadband observations of the naked-eye gamma-ray burst GRB 080319B. Nature (2008) 2.16
Relativistic jet activity from the tidal disruption of a star by a massive black hole. Nature (2011) 2.12
Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig alpha-lactalbumin. Biochemistry (1989) 2.11
Rapid folding with and without populated intermediates in the homologous four-helix proteins Im7 and Im9. J Mol Biol (1999) 1.97
GroEL accelerates the refolding of hen lysozyme without changing its folding mechanism. Nat Struct Biol (1999) 1.81
Hydrogen exchange in native and denatured states of hen egg-white lysozyme. Proteins (1992) 1.79
Ultrarapid mixing experiments reveal that Im7 folds via an on-pathway intermediate. Nat Struct Biol (2001) 1.72
Conformation of GroEL-bound alpha-lactalbumin probed by mass spectrometry. Nature (1994) 1.65
32P-incorporation PCR for the detection of rearrangements at the TCR-gamma locus. Diagn Mol Pathol (1996) 1.52
Structure and dynamics of the acid-denatured molten globule state of alpha-lactalbumin: a two-dimensional NMR study. Biochemistry (1993) 1.52
Ribosome-mediated folding of partially unfolded ricin A-chain. J Biol Chem (2000) 1.51
Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro. J Mol Biol (2001) 1.51
Computed tomography of the head by the accident and emergency department--why 24 hour access is vital. J Accid Emerg Med (1998) 1.46
Circulating plasma cells in multiple myeloma: characterization and correlation with disease stage. Br J Haematol (1997) 1.45
Demonstration by NMR of folding domains in lysozyme. Nature (1991) 1.44
Investigation of protein folding by mass spectrometry. FASEB J (1996) 1.42
Dissecting the structure of a partially folded protein. Circular dichroism and nuclear magnetic resonance studies of peptides from ubiquitin. J Mol Biol (1993) 1.39
Fermi observations of high-energy gamma-ray emission from GRB 080916C. Science (2009) 1.37
Proline isomerism in staphylococcal nuclease characterized by NMR and site-directed mutagenesis. Nature (1987) 1.37
Tertiary interactions in the folding pathway of hen lysozyme: kinetic studies using fluorescent probes. Biochemistry (1994) 1.33
A partially folded state of hen egg white lysozyme in trifluoroethanol: structural characterization and implications for protein folding. Biochemistry (1993) 1.32
2-Oxo acid dehydrogenase multi-enzyme complexes: in the beginning and halfway there. Biochem Soc Symp (1987) 1.29
Hospitalized incidence and case fatality for upper gastrointestinal bleeding from 1999 to 2007: a record linkage study. Aliment Pharmacol Ther (2011) 1.27
Multiple conformations of a protein demonstrated by magnetization transfer NMR spectroscopy. Nature (1986) 1.27
Fast and slow tracks in lysozyme folding: insight into the role of domains in the folding process. J Mol Biol (1997) 1.27
Systemic lupus erythematosus presenting with cardiac tamponade due to a haemorrhagic pericardial effusion. Postgrad Med J (1987) 1.25
Global analysis of the effects of temperature and denaturant on the folding and unfolding kinetics of the N-terminal domain of the protein L9. J Mol Biol (1998) 1.24
Kinetics of interaction of partially folded proteins with a hydrophobic dye: evidence that molten globule character is maximal in early folding intermediates. Protein Sci (1995) 1.23
Structure and stability of the molten globule state of guinea-pig alpha-lactalbumin: a hydrogen exchange study. Biochemistry (1993) 1.22
Amide hydrogen exchange in a highly denatured state. Hen egg-white lysozyme in urea. J Mol Biol (1994) 1.21
Protein folding mechanisms: new methods and emerging ideas. Curr Opin Struct Biol (2000) 1.19
Chronic low back pain: comparison of bone SPECT with radiography and CT. Radiology (1992) 1.18
The incidence of acute pancreatitis: impact of social deprivation, alcohol consumption, seasonal and demographic factors. Aliment Pharmacol Ther (2013) 1.15
Structural characterization of a mutant peptide derived from ubiquitin: implications for protein folding. Protein Sci (2000) 1.14
Protein folding. Solid evidence for molten globules. Curr Biol (1994) 1.12
Hen egg white lysozyme expressed in, and secreted from, Aspergillus niger is correctly processed and folded. Biotechnology (N Y) (1990) 1.09
Structure of very early protein folding intermediates: new insights through a variant of hydrogen exchange labelling. Fold Des (1996) 1.09
Acidic conditions stabilise intermediates populated during the folding of Im7 and Im9. J Mol Biol (2001) 1.06
Hydrogen exchange properties of proteins in native and denatured states monitored by mass spectrometry and NMR. Protein Sci (1997) 1.02
Significant hydrogen exchange protection in GroEL-bound DHFR is maintained during iterative rounds of substrate cycling. Protein Sci (1996) 1.01
Molecular quantitation of minimal residual disease in acute myeloid leukemia with t(8;21) can identify patients in durable remission and predict clinical relapse. Blood (2000) 1.00
Pseudospecific docking surfaces on electron transfer proteins as illustrated by pseudoazurin, cytochrome c550 and cytochrome cd1 nitrite reductase. Nat Struct Biol (1995) 1.00
Role of the single disulphide bond of beta(2)-microglobulin in amyloidosis in vitro. Protein Sci (2001) 0.99
Autonomous folding of a peptide corresponding to the N-terminal beta-hairpin from ubiquitin. Protein Sci (1999) 0.99
A partially folded intermediate species of the beta-sheet protein apo-pseudoazurin is trapped during proline-limited folding. Protein Sci (2001) 0.99
Thermodynamic consequences of the removal of a disulphide bridge from hen lysozyme. J Mol Biol (1992) 0.99
Investigation of the mechanism of active site coupling in the pyruvate dehydrogenase multienzyme complex of Escherichia coli by protein engineering. J Mol Biol (1988) 0.98
A peptide model for proline isomerism in the unfolded state of staphylococcal nuclease. J Mol Biol (1992) 0.98
Specific glycosaminoglycans promote unseeded amyloid formation from beta2-microglobulin under physiological conditions. Kidney Int (2007) 0.97
The Greek key protein apo-pseudoazurin folds through an obligate on-pathway intermediate. J Mol Biol (1999) 0.97
Kinetic studies of beta-sheet protein folding. Curr Opin Struct Biol (1998) 0.97
Conformational properties of four peptides spanning the sequence of hen lysozyme. J Mol Biol (1995) 0.96
An examination of the accident and emergency management of deliberate self harm. J Accid Emerg Med (1997) 0.96
The significance of B-cell clonality in gastric lymphoid infiltrates. J Pathol (1996) 0.95
Kinetic consequences of the removal of a disulfide bridge on the folding of hen lysozyme. Biochemistry (1994) 0.95
The refolding of human lysozyme: a comparison with the structurally homologous hen lysozyme. Biochemistry (1994) 0.94
A photochemically induced dynamic nuclear polarization study of denatured states of lysozyme. Biochemistry (1991) 0.94
Site-directed mutagenesis and 1H NMR spectroscopy of an interdomain segment in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. Biochemistry (1988) 0.94
Advances in ion mobility spectrometry-mass spectrometry reveal key insights into amyloid assembly. Biochim Biophys Acta (2012) 0.94
Conserved structural features on protein surfaces: small exterior hydrophobic clusters. J Mol Biol (1995) 0.93
GRB 130427A: a nearby ordinary monster. Science (2013) 0.92
The impact of attaining a minimal disease state after high-dose melphalan and autologous transplantation for multiple myeloma. Br J Haematol (2001) 0.92
Thermal unfolding of an intermediate is associated with non-Arrhenius kinetics in the folding of hen lysozyme. J Mol Biol (2000) 0.91
Antibody response of the lactating sow to oral immunization with Escherichia coli. Scand J Immunol (1980) 0.90
The use of CT scanning by accident and emergency departments in the UK: past, present and future. Injury (1995) 0.90
Far-UV circular dichroism reveals a conformational switch in a peptide fragment from the beta-sheet of hen lysozyme. Biochemistry (1994) 0.89
Protein folding: pulling back the frontiers. Curr Biol (2000) 0.89
Acceleration of the folding of hen lysozyme by trifluoroethanol. J Mol Biol (1997) 0.89
The pseudoazurin gene from Thiosphaera pantotropha: analysis of upstream putative regulatory sequences and overexpression in Escherichia coli. Biochem J (1997) 0.88
Topological and stereochemical restrictions in beta-sandwich protein structures. Protein Eng (1993) 0.88
The origin of the alpha-domain intermediate in the folding of hen lysozyme. J Mol Biol (1998) 0.88
A near-native state on the slow refolding pathway of hen lysozyme. Protein Sci (1999) 0.87
A study of cells in the mammary secretions of sows. Vet Immunol Immunopathol (1982) 0.87
Structural and mechanistic consequences of polypeptide binding by GroEL. Fold Des (1997) 0.86
Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia. Leukemia (2010) 0.86
Assessment of IgH PCR strategies in multiple myeloma. J Clin Pathol (1996) 0.86
Crystal structure of the mutant D52S hen egg white lysozyme with an oligosaccharide product. J Mol Biol (1994) 0.85
Protein folding in the absence of the solvent ordering contribution to the hydrophobic interaction. J Mol Biol (1993) 0.85
Analysis of the 1H-NMR chemical shifts of Cu(I)-, Cu(II)- and Cd-substituted pea plastocyanin. Metal-dependent differences in the hydrogen-bond network around the copper site. Eur J Biochem (1996) 0.84
Molecular mechanisms of fibrillogenesis and the protective role of amyloid P component: two possible avenues for therapy. Ciba Found Symp (1996) 0.84
Characteristics of children and adolescents presenting to accident and emergency departments with deliberate self harm. J Accid Emerg Med (2000) 0.84
Solvent isotope effects on the refolding kinetics of hen egg-white lysozyme. Protein Sci (1996) 0.84
Weighing the evidence for structure: electrospray ionization mass spectrometry of proteins. Structure (1995) 0.84
Using chimeric immunity proteins to explore the energy landscape for alpha-helical protein folding. J Mol Biol (2001) 0.84
A mutant pyruvate dehydrogenase complex of Escherichia coli deleted in the (alanine + proline)-rich region of the acetyltransferase component. Biochim Biophys Acta (1987) 0.83
Somatostatin and water excretion in man: an intrarenal action. Clin Endocrinol (Oxf) (1985) 0.83
The role of a beta-bulge in the folding of the beta-hairpin structure in ubiquitin. Protein Sci (2001) 0.82
Detection and accurate sizing of PCR product by automated scanning: improved detection of immunoglobulin gene rearrangements in ALL. Br J Haematol (1993) 0.82
Structure and properties of a dimeric N-terminal fragment of human ubiquitin. J Mol Biol (2001) 0.81