T Leff

Author PubWeight™ 34.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The human apolipoprotein C-II gene sequence contains a novel chromosome 19-specific minisatellite in its third intron. J Biol Chem 1987 2.85
2 Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level. Proc Natl Acad Sci U S A 1984 2.64
3 Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia. J Clin Invest 1995 2.05
4 Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products. Nucleic Acids Res 1985 2.04
5 Human apolipoprotein CIII gene expression is regulated by positive and negative cis-acting elements and tissue-specific protein factors. J Biol Chem 1988 1.64
6 Regulation of transcription by AMP-activated protein kinase: phosphorylation of p300 blocks its interaction with nuclear receptors. J Biol Chem 2001 1.61
7 c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gamma1 and negatively regulates its transcriptional activity. Endocrinology 1999 1.60
8 Transcriptional regulation of the apoC-III gene by insulin in diabetic mice: correlation with changes in plasma triglyceride levels. J Lipid Res 1994 1.40
9 Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit. Nucleic Acids Res 1983 1.40
10 Differential activation of peroxisome proliferator-activated receptor-gamma by troglitazone and rosiglitazone. Diabetes 2000 1.34
11 A novel potent antagonist of peroxisome proliferator-activated receptor gamma blocks adipocyte differentiation but does not revert the phenotype of terminally differentiated adipocytes. Endocrinology 2001 1.19
12 Expression of the human apolipoprotein E gene is regulated by multiple positive and negative elements. J Biol Chem 1988 1.18
13 Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice. J Clin Invest 1994 1.08
14 Sequence-specific activation of transcription by adenovirus EIa products is observed in HeLa cells but not in 293 cells. Mol Cell Biol 1986 1.05
15 Cell type-specific expression of the human apoB gene is controlled by two cis-acting regulatory regions. J Biol Chem 1988 1.04
16 A common Hpa I RFLP of apolipoprotein C-I increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E. J Lipid Res 1999 0.96
17 Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action. J Lipid Res 1995 0.92
18 Mitogen-activated protein kinase regulates transcription of the ApoCIII gene. Involvement of the orphan nuclear receptor HNF4. J Biol Chem 1999 0.92
19 Characterization of a dominant negative mutant form of the HNF-4 orphan receptor. Nucleic Acids Res 1996 0.92
20 Apo CIII gene transcription is regulated by a cytokine inducible NF-kappa B element. Nucleic Acids Res 1994 0.90
21 Nuclear factors AF-1 and C/EBP bind to the human ApoB gene promoter and modulate its transcriptional activity in hepatic cells. J Biol Chem 1990 0.87
22 Troglitazone, an antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome proliferator-activated receptor-gamma. Diabetes 1999 0.86
23 Three isoforms of a hepatocyte nuclear factor-4 transcription factor with tissue- and stage-specific expression in the adult mosquito. J Biol Chem 1998 0.79
24 Regulation of cytochrome P450 in cultured human colonic cells. Arch Biochem Biophys 1993 0.79
25 c-Myc does not require max for transcriptional activity in PC-12 cells. Mol Cell Neurosci 1994 0.79
26 A novel compound that elevates high density lipoprotein and activates the peroxisome proliferator activated receptor. J Lipid Res 1998 0.76
27 Studies of heterologous promoter trans-activation by the HTLV-II tax protein. Nucleic Acids Res 1989 0.75