A study of the physicochemical interactions between biliary lipids and chlorpromazine hydrochloride. Bile-salt precipitation as a mechanism of phenothiazine-induced bile secretory failure.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 1172618)

Published in Biochem J on March 01, 1976

Authors

M C Carey, P C Hirom, D M Small

Articles cited by this

The physicochemical basis of cholesterol gallstone formation in man. J Clin Invest (1968) 5.80

Drug-induced hepatic injury. Ann Intern Med (1959) 2.06

The enterohepatic circulation of bile salts. Arch Intern Med (1972) 1.81

Micellar properties of dihydroxy and trihydroxy bile salts: effects of counterion and temperature. J Colloid Interface Sci (1969) 1.60

The biophysics of lipidic associations. I. The ternary systems: lecithin-bile salt-water. Biochim Biophys Acta (1966) 1.60

Micelle formation by bile salts. Physical-chemical and thermodynamic considerations. Arch Intern Med (1972) 1.45

Cholestasis. Annu Rev Med (1968) 1.17

Validity and sensitivity of an intravenous bile acid tolerance test in patients with liver disease. N Engl J Med (1975) 1.16

Mechanisms and control of secretion of bile water and electrolytes. Gastroenterology (1974) 1.15

Biliary stasis produced by chlorpromazine: an experimental study. Proc Staff Meet Mayo Clin (1955) 1.03

Drug reactions characterized by cholestasis associated with intrahepatic biliary tract obstruction. Am J Med (1957) 1.02

Solubility of bile salts. Nature (1969) 0.99

The effect of chlorpromazine on some properties DNA in solution. Physiol Chem Phys (1975) 0.97

Liver cell necrosis in chlorpromazine jaundice (allergic cholangiolitis). A serial study of twenty-six needle biopsy specimens in nine patients. Am J Med (1959) 0.94

Clinical studies of an anti-emetic agent, chlorpromazine. Am J Med Sci (1954) 0.92

A comparison of the distribution, excretion and metabolism of a tertiary (promethazine) and a quaternary (Aprobit) phenothiazine compound labelled with S35. Arch Int Pharmacodyn Ther (1961) 0.91

Effect of chlorpromazine, chlordiazepoxide, diazepam and chlorprothixene on bile and intrabillary pressure in cholecystectomized dogs. Am J Gastroenterol (1963) 0.91

Surface and solution properties of steroid antibiotics: 3-acetoxylfusidic acid, cephalosporin P1 and helvolic acid. Biochemistry (1975) 0.91

Effect of chlorpromazine on the liver. Gastroenterology (1958) 0.87

Serial liver-function and blood studies in patients receiving chlorpromazine. N Engl J Med (1957) 0.86

Cholestatic drugs and bilirubin metabolism. Nature (1965) 0.85

Physiology of bile flow. Prog Liver Dis (1972) 0.85

Complex formation of chlorpromazine with flavins. Nature (1959) 0.82

Effect of chlorpromazine on the function of the perfused isolated liver. Biochem Pharmacol (1971) 0.81

Interaction of chlorpromazine with strandin. Proc Soc Exp Biol Med (1961) 0.81

Solution properties of taurine and glycine conjugates of fusidic acid and its derivatives. Biochim Biophys Acta (1973) 0.78

Spectrophotometric method for the determination of chlorpromazine and chlorpromazine sulphoxide in biological fluids. J Med Pharm Chem (1959) 0.78

Biliary and urinary excretion patterns of chlorpromazine in the dog. J Pharm Sci (1962) 0.77

The effect of chlorpromazine on hepatic function and morphology. Gastroenterology (1956) 0.77

Molecular interaction and its relation to the formation of sodium dodecylsulphate-cetyltrimethylammonium bromide complex. Nature (1951) 0.77

INTERACTIONS BETWEEN ORANGE II AND SELECTED LONG CHAIN QUATERNARY AMMONIUM SALTS. J Pharm Sci (1964) 0.77

Effects of phenothiazines on the surface pressures, potentials and viscosities of monolayers of lecithin and-or cholesterol. Agents Actions (1969) 0.77

Interaction of chlorpromazine with bile. Clin Chem (1971) 0.77

Effects of interaction with surfactants, adsorbents, and other substances on the permeation of chlorpromazine through a dimethyl polysiloxane membrane. J Pharm Sci (1971) 0.77

Micellar properties of drugs: properties of micellar aggregates of phenothiazines and their aqueous solutions. J Pharm Sci (1974) 0.77

[On alteration of bromsulfophthalein excretion in the bile of rats after prolonged chlorpromazine administration]. Wien Klin Wochenschr (1960) 0.76

Surface activity of chlorpromazine and chlorpromazine sulfoxide in the presence of insoluble monomolecular films. J Pharm Sci (1965) 0.76

THE BINDING OF POLYPHOSPHATES BY PHENOTHIAZINES AND RELATED COMPOUNDS: A POSSIBLE RELATIONSHIP TO CLINICAL POTENCY AS TRANQUILISERS. Biochem Pharmacol (1964) 0.76

HEPATIC SECRETION AND URINARY EXCRETION OF THREE S35-LABELED PHENOTHIAZINES IN THE DOG. J Pharm Sci (1964) 0.76

Distribution of phenothiazines in tissue. Psychopharmacol Serv Cent Bull (1962) 0.76

Articles by these authors

Nature of the Thermal pretransition of synthetic phospholipids: dimyristolyl- and dipalmitoyllecithin. Biochemistry (1976) 7.37

The physicochemical basis of cholesterol gallstone formation in man. J Clin Invest (1968) 5.80

Phase equilibria and structure of dry and hydrated egg lecithin. J Lipid Res (1967) 5.02

Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele. Science (2008) 4.94

Temperature and compositional dependence of the structure of hydrated dimyristoyl lecithin. J Biol Chem (1979) 4.65

Critical tables for calculating the cholesterol saturation of native bile. J Lipid Res (1978) 3.45

Detergent properties of bile salts: correlation with physiological function. Annu Rev Med (1967) 3.25

The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man. J Clin Invest (1978) 2.51

Biliary lipid secretion in cholesterol gallstone disease. The effect of cholecystectomy and obesity. J Clin Invest (1977) 2.12

Effects of controlled interruption of the enterohepatic circulation of bile salts by biliary diversion and by ileal resection on bile salt secretion, synthesis, and pool size in the rhesus monkey. J Clin Invest (1970) 2.05

Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques. J Clin Invest (1976) 2.05

Source of abnormal bile in patients with cholesterol gallstones. N Engl J Med (1970) 2.01

Role of gallbladder mucus hypersecretion in the evolution of cholesterol gallstones. J Clin Invest (1981) 1.99

Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule. Biochemistry (1988) 1.94

Lipid digestion and absorption. Annu Rev Physiol (1983) 1.93

The formation of gallstones. Adv Intern Med (1970) 1.81

The enterohepatic circulation of bile salts. Arch Intern Med (1972) 1.81

Quasielastic light-scattering studies of aqueous biliary lipid systems. Mixed micelle formation in bile salt-lecithin solutions. Biochemistry (1980) 1.80

The biliary excretion of tartrazine. Sex differences in the rat and species differences in the rat, guinea-pig and rabbit. J Pharm Pharmacol (1972) 1.77

Enterohepatic cycling of bilirubin: a putative mechanism for pigment gallstone formation in ileal Crohn's disease. Gastroenterology (1999) 1.74

Thermal transitions in human plasma low density lipoproteins. Science (1975) 1.72

Food and drug cues activate similar brain regions: a meta-analysis of functional MRI studies. Physiol Behav (2012) 1.68

Bile composition at and after surgery in normal persons and patients with gallstones. Influence of cholecystectomy. N Engl J Med (1972) 1.68

The phase behavior of hydrated cholesterol. J Lipid Res (1979) 1.67

Bilirubin cycles enterohepatically after ileal resection in the rat. Gastroenterology (1996) 1.65

Physical-chemical basis of lipid deposition in atherosclerosis. Science (1974) 1.63

Micellar properties of dihydroxy and trihydroxy bile salts: effects of counterion and temperature. J Colloid Interface Sci (1969) 1.60

The biophysics of lipidic associations. I. The ternary systems: lecithin-bile salt-water. Biochim Biophys Acta (1966) 1.60

Biophysics of lipid associations. 3. The quaternary systems lecithin-bile salt-cholesterol-water. Biochim Biophys Acta (1967) 1.57

Species variations in the threshold molecular-weight factor for the biliary excretion of organic anions. Biochem J (1972) 1.57

Structure and interactions of lipids in human plasma low density lipoproteins. J Biol Chem (1977) 1.55

Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: soluble pronucleating proteins in gallbladder and hepatic biles. J Hepatol (2001) 1.55

Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings. Biochemistry (1990) 1.54

Biophysics of lipidic associations. II. The ternary systems: cholesterol-lecithin-water. Biochim Biophys Acta (1967) 1.53

The characteristics of mixed micellar solutions with particular reference to bile. Am J Med (1970) 1.53

Recombinant lipoproteins: implications for structure and assembly of native lipoproteins. Annu Rev Biophys Biophys Chem (1986) 1.51

Physicochemical and histological changes in the arterial wall of nonhuman primates during progression and regression of atherosclerosis. J Clin Invest (1984) 1.50

Ursodeoxycholic acid and cholesterol induce enterohepatic cycling of bilirubin in rodents. Gastroenterology (1998) 1.48

Complete mapping of crystallization pathways during cholesterol precipitation from model bile: influence of physical-chemical variables of pathophysiologic relevance and identification of a stable liquid crystalline state in cold, dilute and hydrophilic bile salt-containing systems. J Lipid Res (1996) 1.47

Micelle formation by bile salts. Physical-chemical and thermodynamic considerations. Arch Intern Med (1972) 1.45

Protein-lipid interactions: recombinants of the proteolipid apoprotein of myelin with dimyristoyllecithin. Biochemistry (1977) 1.44

Plasma high-density lipoproteins. N Engl J Med (1978) 1.44

Ternary and quaternary aqueous systems containing bile salt, lecithin, and cholesterol. Nature (1966) 1.44

Gallstones. N Engl J Med (1968) 1.43

Calcium affinity for biliary lipid aggregates in model biles: complementary importance of bile salts and lecithin. Gastroenterology (1994) 1.43

Lith1, a major gene affecting cholesterol gallstone formation among inbred strains of mice. Proc Natl Acad Sci U S A (1995) 1.42

Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: physical-chemistry of gallbladder bile. J Lipid Res (1997) 1.41

The hydrophobic-hydrophilic balance of bile salts. Inverse correlation between reverse-phase high performance liquid chromatographic mobilities and micellar cholesterol-solubilizing capacities. J Lipid Res (1982) 1.41

Bile composition, bile salt metabolism and gallstones. Arch Intern Med (1972) 1.38

Bile and urine as complementary pathways for the excretion of foreign organic compounds. Xenobiotica (1976) 1.38

Mechanical properties of model atherosclerotic lesion lipid pools. Arterioscler Thromb (1994) 1.35

Aspirin prevention of cholesterol gallstone formation in prairie dogs. Science (1981) 1.34

A classification of biologic lipids based upon their interaction in aqeous systems. J Am Oil Chem Soc (1968) 1.33

Reverse-phase h.p.l.c. separation, quantification and preparation of bilirubin and its conjugates from native bile. Quantitative analysis of the intact tetrapyrroles based on h.p.l.c. of their ethyl anthranilate azo derivatives. Biochem J (1985) 1.33

Structure of human plasma low-density lipoproteins: molecular organization of the central core. Proc Natl Acad Sci U S A (1977) 1.30

Biliary lipid secretion and bile composition after acute and chronic interruption of the enterohepatic circulation in the Rhesus monkey. IV. Primate biliary physiology. J Clin Invest (1971) 1.29

Experimental model for the study of the enterohepatic circulation of bile in rhesus monkeys. J Lab Clin Med (1968) 1.29

Studies on simple and mixed bile salt micelles by nuclear magnetic resonance spectroscopy. Biochim Biophys Acta (1969) 1.29

Structure and thermodynamic properties of high density lipoprotein recombinants. J Biol Chem (1977) 1.28

Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death. Arterioscler Thromb Vasc Biol (1998) 1.26

Transbilayer movement of bile acids in model membranes. Biochemistry (1987) 1.24

Body cholesterol removal: role of plasma high-density lipoproteins. Adv Lipid Res (1980) 1.23

Phase behavior and structural characteristics of hydrated bovine brain gangliosides. Biochim Biophys Acta (1977) 1.23

X-ray diffraction and calorimetric study of anhydrous and hydrated N-palmitoylgalactosylsphingosine (cerebroside). Biochemistry (1981) 1.23

Quantitation of the transfer of surface phospholipid of chylomicrons to the high density lipoprotein fraction during the catabolism of chylomicrons in the rat. J Clin Invest (1979) 1.22

Phenotypic characterization of lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice. Pathophysiology Of biliary lipid secretion. J Lipid Res (1999) 1.22

Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings. Biochemistry (1990) 1.22

Filamentous, helical, and tubular microstructures during cholesterol crystallization from bile. Evidence that cholesterol does not nucleate classic monohydrate plates. J Clin Invest (1992) 1.21

Lateral chain packing in lipids and membranes. J Lipid Res (1984) 1.20

Editorial: Hormone use to change normal physiology - is the risk worth it? N Engl J Med (1976) 1.19

Phase behavior and bilayer properties of fatty acids: hydrated 1:1 acid-soaps. Biochemistry (1986) 1.18

Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites. J Biol Chem (1987) 1.18

The lipid composition of drusen, Bruch's membrane, and sclera by hot stage polarizing light microscopy. Invest Ophthalmol Vis Sci (2001) 1.17

The interfacial conformation and transbilayer movement of diacylglycerols in phospholipid bilayers. J Biol Chem (1991) 1.17

Sex and species differences in the biliary excretion of tartrazine and lissamine fast yellow in the rat, guinea-pig and rabbit. The influence of sex hormones on tartrazine excretion in the rat. J Pharm Pharmacol (1972) 1.16

Primate biliary physiology. 8. The effect of phenobarbital upon bile salt synthesis and pool size, biliary lipid secretion, and bile composition. J Clin Invest (1973) 1.16

Solubilization and localization of triolein in phosphatidylcholine bilayers: a 13C NMR study. Proc Natl Acad Sci U S A (1981) 1.15

Quasi-elastic light-scattering studies of aqueous biliary lipid systems. Cholesterol solubilization and precipitation in model bile solutions. Biochemistry (1983) 1.14

Interactions of the carboxyl group of oleic acid with bovine serum albumin: a 13C NMR study. J Biol Chem (1983) 1.14

Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. II. Electrostatic interactions in individual fatty acid binding sites. J Biol Chem (1987) 1.13

The affinity of cholesterol for phosphatidylcholine and sphingomyelin. Biochim Biophys Acta (1979) 1.13

Quasielastic light scattering studies of aqueous biliary lipid systems. Size, shape, and thermodynamics of bile salt micelles. Biochemistry (1979) 1.12

Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters. J Biol Chem (1987) 1.11

Molecular weight and chemical structure as factors in the biliary excretion of sulphonamides in the rat. Xenobiotica (1972) 1.10

Phase behavior and structure of aqueous dispersions of sphingomyelin. J Lipid Res (1974) 1.10

Effects of bile and bile salts on growth and membrane lipid uptake by Giardia lamblia. Possible implications for pathogenesis of intestinal disease. J Clin Invest (1985) 1.10

Surface-to-core and interparticle equilibrium distributions of triglyceride-rich lipoprotein lipids. J Biol Chem (1983) 1.10

Physical properties of cholesteryl esters. Prog Lipid Res (1984) 1.10

Triolein-cholesteryl oleate-cholesterol-lecithin emulsions: structural models of triglyceride-rich lipoproteins. Biochemistry (1983) 1.10

Genetic factors at the enterocyte level account for variations in intestinal cholesterol absorption efficiency among inbred strains of mice. J Lipid Res (2001) 1.09

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map. Gastroenterology (2001) 1.09

Laser light scattering evidence for a common wormlike growth structure of mixed micelles in bile salt- and straight-chain detergent-phosphatidylcholine aqueous systems: relevance to the micellar structure of bile. Biochemistry (1998) 1.08

The biliary excretion of anions of molecular weight 300-800 in the rat, guinea pig and rabbit. Biochem J (1971) 1.07

Formation of cholesterol monohydrate crystals in macrophage-derived foam cells. J Lipid Res (1994) 1.07