J G Kelton

Author PubWeight™ 174.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood 1996 7.31
2 Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995 6.86
3 Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group. N Engl J Med 1991 4.66
4 Temporal aspects of heparin-induced thrombocytopenia. N Engl J Med 2001 2.89
5 Impact of the patient population on the risk for heparin-induced thrombocytopenia. Blood 2000 2.78
6 Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia. Blood 1991 2.54
7 Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review. J Thromb Haemost 2015 2.46
8 A prospective study to determine the safety of omitting the antiglobulin crossmatch from pretransfusion testing. Br J Haematol 1992 2.18
9 The role of the plasma from platelet concentrates in transfusion reactions. N Engl J Med 1994 2.09
10 Fetal thrombocytopenia and its relation to maternal thrombocytopenia. N Engl J Med 1993 2.08
11 Bacterial infection-associated improvement of platelet counts in two patients with chronic and unresponsive idiopathic thrombocytopenic purpura with normal platelet survival studies. Br J Haematol 1995 2.07
12 High-dose intravenous immune globulin and the response to splenectomy in patients with idiopathic thrombocytopenic purpura. N Engl J Med 1997 2.05
13 A 14-year study of heparin-induced thrombocytopenia. Am J Med 1996 2.03
14 A prospective study to determine the frequency and clinical significance of alloimmunization post-transfusion. Br J Haematol 1995 2.01
15 The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia. Ann Intern Med 1997 2.00
16 Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays. J Thromb Haemost 2008 1.75
17 Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation 2001 1.64
18 A prospective study to identify the risk factors associated with acute reactions to platelet and red cell transfusions. Transfusion 1993 1.52
19 Activation of platelets by sera containing IgG1 heparin-dependent antibodies: an explanation for the predominance of the Fc gammaRIIa "low responder" (his131) gene in patients with heparin-induced thrombocytopenia. J Lab Clin Med 1997 1.51
20 Splenectomy done during hematologic remission to prevent relapse in patients with thrombotic thrombocytopenic purpura. Ann Intern Med 1996 1.48
21 Thrombogenic effect of high-dose aspirin in rabbits. Relationship to inhibition of vessel wall synthesis of prostaglandin I2-like activity. J Clin Invest 1978 1.43
22 Low fetal risks in pregnancies associated with idiopathic thrombocytopenic purpura. Am J Obstet Gynecol 1990 1.43
23 A novel congenital haemostatic defect: combined factor VII and factor XI deficiency. Blood Coagul Fibrinolysis 1992 1.42
24 Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia. Blood 1994 1.39
25 A Canadian hospital-based HIV/hepatitis C look-back notification program. CMAJ 1997 1.38
26 Heparin-associated thrombocytopenia. Ann Intern Med 1984 1.35
27 Delayed-onset heparin-induced thrombocytopenia and thrombosis. Ann Intern Med 2001 1.30
28 Immune-mediated thrombocytopenia of malaria. J Clin Invest 1983 1.28
29 A diagnostic test for heparin-induced thrombocytopenia. Blood 1986 1.27
30 Gestational thrombocytopenia. Clin Obstet Gynecol 1999 1.24
31 A prospective study of the usefulness of the measurement of platelet-associated IgG for the diagnosis of idiopathic thrombocytopenic purpura. Blood 1982 1.21
32 Management of idiopathic thrombocytopenic purpura in pregnancy. Semin Hematol 2000 1.19
33 Drug-induced thrombocytopenia is associated with increased binding of IgG to platelets both in vivo and in vitro. Blood 1981 1.14
34 Thrombocytopenia at delivery: a prospective survey of 6715 deliveries. Am J Obstet Gynecol 1990 1.12
35 Infection-induced thrombocytopenia. Semin Thromb Hemost 1982 1.10
36 A systematic evaluation of laboratory testing for drug-induced immune thrombocytopenia. J Thromb Haemost 2013 1.10
37 The relationship between the hemorrhagic and antithrombotic properties of low molecular weight heparin in rabbits. Blood 1982 1.10
38 Clinical impact of neonatal thrombocytopenia. J Pediatr 1987 1.09
39 Heparin-induced thrombocytopenia. Annu Rev Med 1989 1.08
40 A prospective study of protein-specific assays used to investigate idiopathic thrombocytopenic purpura. Br J Haematol 1999 1.08
41 Autoimmune platelet destruction: idiopathic thrombocytopenic purpura. Semin Thromb Hemost 1982 1.07
42 Elevated platelet-associated IgG in the thrombocytopenia of septicemia. N Engl J Med 1979 1.06
43 Vaccination-Associated relapse of immune thrombocytopenia. JAMA 1981 1.06
44 The direct assay for platelet-associated IgG (PAIgG): lack of association between antibody level and platelet size. Blood 1979 1.05
45 Pregnancy in patients with idiopathic thrombocytopenic purpura: assessing the risks for the infant at delivery. Obstet Gynecol Surv 1993 1.04
46 Digitalis toxicity manifested by dysphagia. JAMA 1978 1.02
47 The use of in vitro technics to study drug-induced pancytopenia. N Engl J Med 1979 1.01
48 Heparin-induced thrombocytopenia. Prog Hemost Thromb 1991 1.01
49 Incidentally detected thrombocytopenia in healthy mothers and their infants. N Engl J Med 1988 1.00
50 Neonatal thrombocytopenia due to passive immunization: prenatal diagnosis and distinction between maternal platelet alloantibodies and autoantibodies. N Engl J Med 1980 1.00
51 Morphological analysis of microparticle generation in heparin-induced thrombocytopenia. Blood 2000 1.00
52 Heparin and platelets. Hematol Oncol Clin North Am 1990 0.99
53 Bleeding associated with antithrombotic therapy. Semin Hematol 1980 0.98
54 Antiplatelet agents: rationale and results. Clin Haematol 1983 0.98
55 Comparison of chemical composition of peritoneal fluid and serum: a method for monitoring dialysis patients and a tool for assessing binding to serum proteins in vivo. Ann Intern Med 1978 0.97
56 Thrombocytopenia in septicemia: the role of disseminated intravascular coagulation. Blood 1980 0.94
57 Thrombocytopenia in pregnancy: diagnosis, pathogenesis and management. Blood Rev 1996 0.94
58 Decreased von Willebrand factor protease activity associated with thrombocytopenic disorders. Blood 2001 0.94
59 An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect. Blood 1996 0.93
60 The epitope specificity of heparin-induced thrombocytopenia. Br J Haematol 1996 0.90
61 p-155, a multimeric platelet protein that is expressed on activated platelets. J Biol Chem 1991 0.90
62 Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia. J Lab Clin Med 1992 0.89
63 Comparison of two direct assays for platelet-associated IgG (PAIgG) in assessement of immune and nonimmune thrombocytopenia. Blood 1980 0.89
64 The relationship among platelet-associated IgG, platelet lifespan, and reticuloendothelial cell function. Blood 1984 0.89
65 Heparin-induced thrombocytopenia and thrombosis: clinical and laboratory studies. Br J Haematol 1993 0.88
66 A prospective study investigating the mechanism of thrombocytopenia in preeclampsia. Obstet Gynecol 1987 0.88
67 Valproic acid and thrombocytopenia. Can Med Assoc J 1981 0.87
68 111In-oxine platelet survivals in thrombocytopenic infants. Blood 1987 0.87
69 Thrombocytopenia in preeclampsia and eclampsia. Semin Thromb Hemost 1982 0.87
70 Management of the pregnant patient with idiopathic thrombocytopenic purpura. Ann Intern Med 1983 0.87
71 The cDNA sequence of human endothelial cell multimerin. A unique protein with RGDS, coiled-coil, and epidermal growth factor-like domains and a carboxyl terminus similar to the globular domain of complement C1q and collagens type VIII and X. J Biol Chem 1995 0.87
72 Studies on the frequency of heparin-associated thrombocytopenia. Thromb Res 1984 0.86
73 Thrombocytopenia caused by passive transfusion of anti-glycoprotein Ia/IIa alloantibody (anti-HPA-5b). Blood 1992 0.86
74 Calpain proteolysis of von Willebrand factor enhances its binding to platelet membrane glycoprotein IIb/IIIa: an explanation for platelet aggregation in thrombotic thrombocytopenic purpura. Br J Haematol 1990 0.86
75 Increased mortality in hemodialysis patients having specific antibodies to the platelet factor 4-heparin complex. Kidney Int 2007 0.85
76 Investigation of human platelet alloantigens and glycoproteins using non-radioactive immunoprecipitation. J Immunol Methods 1993 0.85
77 Multimerin is found in the alpha-granules of resting platelets and is synthesized by a megakaryocytic cell line. J Clin Invest 1993 0.85
78 Perinatal thrombocytopenia. Clin Perinatol 1995 0.85
79 Investigation of the mechanisms of monoclonal antibody-induced platelet activation. Blood 1991 0.85
80 Plasma glycocalicin. An aid in the classification of thrombocytopenic disorders. N Engl J Med 1987 0.85
81 Multimerin: a series of large disulfide-linked multimeric proteins within platelets. Blood 1991 0.85
82 The development and application of a serum assay for platelet-bindable IgG (S-PBIgG). J Lab Clin Med 1981 0.85
83 The use of well-characterized sera for the assessment of new diagnostic enzyme-immunoassays for the diagnosis of heparin-induced thrombocytopenia. J Thromb Haemost 2009 0.84
84 Substitution of the "group-and-screen" for the full crossmatch in elective operations. Can Anaesth Soc J 1983 0.84
85 A diagnostic test for heparin-induced thrombocytopenia: detection of platelet microparticles using flow cytometry. Br J Haematol 1996 0.84
86 The amount of platelet-bound albumin parallels the amount of IgG on washed platelets from patients with immune thrombocytopenia. Blood 1983 0.84
87 Methyldopa-induced autoantibodies against red blood cells. Blood Rev 1988 0.84
88 Idiopathic immune thrombocytopenic purpura: an update. Semin Hematol 2000 0.84
89 Quantitation of red cell-associated IgG using an immunoradiometric assay. Transfusion 1985 0.84
90 The concentration of IgG in the serum is a major determinant of Fc-dependent reticuloendothelial function. Blood 1985 0.83
91 Current concepts in the treatment of immune thrombocytopenia. Drugs 1990 0.83
92 Quantitation of red cell membrane associated immunoglobulin in children with Plasmodium falciparum parasitaemia. Br J Haematol 1983 0.83
93 Inappropriate antidiuretic hormone complicating histiocytic lymphoma. Arch Intern Med 1979 0.83
94 Platelet transfusions. Can Med Assoc J 1979 0.83
95 Laboratory abnormalities in thrombotic thrombocytopenic purpura. Canadian Apheresis Group. Br J Haematol 1998 0.83
96 FcγRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia. J Thromb Haemost 2013 0.83
97 Relationship between the antithrombotic and anticoagulant effects of low molecular weight heparin. Thromb Res 1981 0.83
98 The quantitation of platelet-associated IgG on cohorts of platelets separated from healthy individuals by buoyant density centrifugation. Blood 1982 0.82
99 Eradication of Rh hemolytic disease of the newborn. Can Med Assoc J 1980 0.82
100 Prostaglandin I2 (prostacyclin). Can Med Assoc J 1980 0.82
101 Heparin-induced thrombocytopenia. Haemostasis 1986 0.82
102 Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation. Thromb Res 1982 0.81
103 Splenic radiation for corticosteroid-resistant immune thrombocytopenia. Ann Intern Med 1992 0.81
104 Characterization and localization of the Gova/b alloantigens to the glycosylphosphatidylinositol-anchored protein CDw109 on human platelets. Blood 1995 0.81
105 Three examples of Rh haemolytic disease of the newborn with a negative direct antiglobulin test. Transfus Med 1995 0.81
106 Factor V is complexed with multimerin in resting platelet lysates and colocalizes with multimerin in platelet alpha-granules. J Biol Chem 1995 0.81
107 Measurement of platelet-associated IgG in animal models of immune and nonimmune thrombocytopenia. Blood 1987 0.81
108 The measurement of platelet-bound immunoglobulins: an overview of the methods and the biological relevance of platelet-associated IgG. Prog Hematol 1983 0.81
109 Impaired reticuloendothelial function in patients treated with methyldopa. N Engl J Med 1985 0.80
110 Serum-induced platelet procoagulant activity: an assay for the characterization of prothrombotic disorders. J Lab Clin Med 1999 0.80
111 The diagnostic value of the fibrinogen/fibrin fragment E antigen assay in clinically suspected deep vein thrombosis. Blood 1982 0.80
112 HLA-DR expression by platelets in acute idiopathic thrombocytopenic purpura. Br J Haematol 1992 0.80
113 Clinical usefulness of testing for a heparin-dependent platelet-aggregating factor in patients with suspected heparin-associated thrombocytopenia. J Lab Clin Med 1984 0.80
114 Drug-induced platelet destruction. Semin Thromb Hemost 1982 0.79
115 Spurious hyperkalaemia associated with severe thrombocytosis and leukocytosis. Can J Anaesth 1991 0.79
116 Anticonvulsant-induced marrow suppression and immune thrombocytopenia. Acta Haematol 1988 0.79
117 Calcium-dependent cysteine protease activity in the sera of patients with thrombotic thrombocytopenic purpura. Blood 1987 0.79
118 Sex-related differences in platelet aggregation: influence of the hematocrit. Blood 1980 0.79
119 The association between platelet activation and FcγRIIa proteolysis. J Thromb Haemost 2011 0.79
120 Somatostatin treatment for cryptosporidial diarrhea in a patient with the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1988 0.79
121 Platelet IgG Fc receptor. Am J Hematol 1987 0.79
122 Current controversies concerning the measurement of platelet-associated IgG. Transfus Med Rev 1990 0.79
123 The amount of blood group A substance on platelets is proportional to the amount in the plasma. Blood 1982 0.79
124 A platelet function defect in preeclampsia. Obstet Gynecol 1985 0.79
125 Comparison of the measurement of surface or total platelet-associated IgG in the diagnosis of immune thrombocytopenia. Am J Hematol 1985 0.78
126 Hypergammaglobulinemia can be associated with a positive direct antiglobulin test, a nonreactive eluate, and no evidence of hemolysis. Transfusion 1988 0.78
127 Abnormal platelet function and arachidonate metabolism in chronic idiopathic thrombocytopenic purpura. Blood 1981 0.78
128 Heparin-induced thrombocytopenia. Semin Thromb Hemost 1986 0.78
129 Intravenous immunoglobulin as an adjunct to plasma exchange for the treatment of chronic thrombotic thrombocytopenic purpura. Vox Sang 2007 0.78
130 The use of electron microscopy in the investigation of the ultrastructural morphology of immune thrombocytopenic purpura platelets. Semin Hematol 2000 0.78
131 In vitro evaluation of prestorage pooled leukoreduced whole blood-derived platelets stored for up to 7 days. Transfusion 2005 0.78
132 Acute calf pain and swelling in the arthritic patient: rupture of a popliteal cyst or deep venous thrombosis? Can Med Assoc J 1981 0.78
133 A comparison of the quantitative ristocetin von Willebrand factor assay by using fresh and fixed platelets. Thromb Res 1980 0.77
134 A prospective study measuring the development of antibodies against platelet factor 4-heparin in healthy males after exposure to heparins. J Thromb Haemost 2012 0.77
135 Multimerin. Curr Opin Hematol 1995 0.77
136 Maternal immunization to Gov system alloantigens on human platelets. Transfusion 1997 0.77
137 Alloimmune thrombocytopenia after organ transplantation. N Engl J Med 1999 0.77
138 The prenatal prediction of thrombocytopenia in infants of mothers with clinically diagnosed immune thrombocytopenia. Am J Obstet Gynecol 1982 0.77
139 Advances in the diagnosis and management of ITP. Hosp Pract (Off Ed) 1985 0.77
140 Sex differences in the antithrombotic effects of aspirin. Blood 1978 0.77
141 Neonatal alloimmune thrombocytopenia: spontaneous in utero intracranial hemorrhage. Am J Hematol 1988 0.76
142 Heparin-induced thrombocytopenia: what the serologists have taught us. J Lab Clin Med 1996 0.76
143 An algorithm for resolving 'indeterminate' test results in the platelet serotonin release assay for investigation of heparin-induced thrombocytopenia. J Thromb Haemost 2008 0.76
144 Sex related differences in platelet function: the effect of aspirin. Blood 1982 0.76
145 Bleeding time in hemophilia A: potential mechanisms for prolongation. J Pediatr 1986 0.76
146 Failure of pulse high-dose dexamethasone in chronic idiopathic immune thrombocytopenia. Am J Hematol 1997 0.76
147 Granulocytes do not have surface ABO antigens. Transfusion 1985 0.76
148 The use of anti-D to improve post-transfusion platelet response: a randomized trial. Br J Haematol 1995 0.75
149 Intravenous IgG: A New Therapeutic Tool. Can Fam Physician 1988 0.75
150 Calpain activity in bone marrow transplant-associated thrombotic thrombocytopenic purpura. Bone Marrow Transplant 1999 0.75
151 Blood component therapy. Can Fam Physician 1984 0.75
152 Heparin-induced skin necrosis. Am J Med 1993 0.75
153 Laboratory investigation of immune thrombocytopenia. J Clin Pathol 1997 0.75
154 Assessing the effectiveness of whole blood-derived platelets stored as a pool: a randomized block noninferiority trial. Transfusion 2005 0.75
155 Diagnosis of heparin-induced thrombocytopenia. Still a journey, not yet a destination. Am J Clin Pathol 1995 0.75
156 Testing for heparin-induced thrombocytopenia: are we there yet? J Thromb Haemost 2007 0.75
157 The effect of aspirin on the size of the hemostatic plug. Thromb Res 1983 0.75
158 Multimerin: A Multimeric Protein Stored in Platelet Alpha-granules. Platelets 1995 0.75
159 RhD status of a fetus at risk for haemolytic disease with a discrepant maternal DNA-based RhD genotype. Prenat Diagn 1999 0.75
160 Measurement of endogenous and exogenous alpha-granular platelet proteins in patients with immune and nonimmune thrombocytopenia. Br J Haematol 1999 0.75
161 Correlation of a quinidine-induced platelet-specific antibody with development of thrombocytopenia. Am J Med 1985 0.75
162 The production of human monoclonal antiplatelet auto-antibodies derived from human lymphocytes of normal origin: reactivity to DNA, anionic phospholipids and platelet proteins. Br J Haematol 1992 0.75
163 The measurement of platelet-associated IgG using an immunoradiometric assay. J Immunoassay 1983 0.75
164 Idiosyncratic drug-induced thrombocytopenia. Curr Stud Hematol Blood Transfus 1986 0.75
165 The prenatal identification of fetal compatibility in neonatal alloimmune thrombocytopenia using amniotic fluid and variable number of tandem repeat (VNTR) analysis. Br J Haematol 1995 0.75
166 Factor V Leiden and thrombotic complications in heparin-induced thrombocytopenia. Thromb Haemost 1998 0.75
167 Platelet specific alloantigens on the platelet glycoprotein Ia/IIa complex. Br J Haematol 1989 0.75
168 The development of a bacteriophage expression vector for cloning immunoglobulin variable region genes from B-cell genomic DNA. Ann N Y Acad Sci 1995 0.75
169 Studies investigating platelet aggregation and release initiated by sera from patients with thrombotic thrombocytopenic purpura. Blood 1987 0.75
170 Alloimmune neonatal thrombocytopenia associated with incidental maternal thrombocytopenia. Am J Hematol 1990 0.75
171 The reversible binding of vinblastine to platelets: implications for therapy. Blood 1981 0.75
172 Thrombotic thrombocytopenic purpura. Blood Coagul Fibrinolysis 1992 0.75
173 Immune haemolytic anaemia and thrombocytopenia: drugs and autoantibodies. Biochem Soc Trans 1991 0.75
174 Investigation of a platelet factor 4 polymorphism on the immune response in patients with heparin-induced thrombocytopenia. Platelets 2000 0.75
175 The detection of a platelet-agglutinating factor in thrombotic thrombocytopenic purpura. Ann Intern Med 1984 0.75
176 Relationship between platelet aggregating factor and von Willebrand factor in thrombotic thrombocytopenic purpura. Br J Haematol 1987 0.75
177 Platelet autoantibodies in septicaemia. Br J Haematol 1985 0.75
178 Monoclonal antibodies against platelet glycoproteins. Transfus Med Rev 1993 0.75
179 Exceptionally high arterial oxygen tension in diabetic ketoacidosis. South Med J 1979 0.75
180 Angioimmunoblastic lymphadenopathy associated with reserpine. Lancet 1984 0.75
181 Idiosyncratic drug-induced thrombocytopenia. Curr Stud Hematol Blood Transfus 1988 0.75
182 Platelet associated IgG--an overview. Clin Res 1985 0.75
183 Proteolytic degradation of high molecular weight kininogen in acute thrombotic thrombocytopenic purpura. Br J Haematol 1997 0.75
184 Platelet-associated IgG in septicemia. N Engl J Med 1979 0.75
185 A human monoclonal autoantibody to platelet glycoprotein IIb derived from normal human lymphocytes. Blood 1992 0.75
186 Immune thrombocytopenic purpura. J Clin Rheumatol 1997 0.75
187 Rabbit Platelets do not Express Fc Receptors for IgG. Platelets 1992 0.75
188 A study of the bioavailability and platelet inhibitory effects of a new enteric-coated acetylsalicylic acid preparation. Thromb Res 1984 0.75
189 The production of platelet controls for assays quantitating platelet-associated IgG. Transfusion 1984 0.75
190 Antibody-mediated platelet activation. J Lab Clin Med 1993 0.75
191 Use of intravenous gammaglobulin as an immune replacement and an immune suppressant. Transfus Med Rev 1989 0.75
192 Platelet survival studies. An overview of the factors affecting the efficiency and reliability of platelet radiolabeling. Transfusion 1986 0.75
193 Dermatomyositis associated with platelet thrombi formation and responsive to antiplatelet therapy. J Rheumatol 1983 0.75
194 Platelet fragments do not contribute to elevated levels of platelet associated IgG. Br J Haematol 1985 0.75
195 Assessment of the optimal anticoagulant solution for storage of whole blood samples prior to measurement of platelet-associated IgG. Transfusion 1982 0.75
196 Platelet immunobiology. Transfus Med Rev 1990 0.75
197 Comparison of the haemorrhagic effects of porcine and bovine heparin in rabbits. Thromb Res 1979 0.75