Published in Gut on November 01, 1993
Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency. Nutr Cancer (2002) 1.49
Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence. Br J Cancer (2002) 0.98
Gastrin and the growth of the gastrointestinal tract. Gut (1995) 0.84
Helicobacter pylori infection and colorectal carcinoma: is there a causal association? J Gastrointest Oncol (2012) 0.79
The National Cancer Institute's PREVENT Cancer Preclinical Drug Development Program: overview, current projects, animal models, agent development strategies, and molecular targets. Semin Oncol (2015) 0.75
A Review of the Novel Application and Potential Adverse Effects of Proton Pump Inhibitors. Adv Ther (2017) 0.75
Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450. Gastroenterology (1990) 4.78
Optimal dose of oral omeprazole for maximal 24 hour decrease of intragastric acidity. Gut (1984) 3.18
Toxicological studies on omeprazole. Scand J Gastroenterol Suppl (1985) 2.19
Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract. Gastroenterology (1992) 2.10
Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy. Cancer Res (1988) 1.76
New aspects of the trophic action of gastrointestinal hormones. Gastroenterology (1977) 1.74
Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon. Carcinogenesis (1991) 1.74
Intragastric bacterial activity and nitrosation before, during, and after treatment with omeprazole. Br Med J (Clin Res Ed) (1984) 1.61
Enterochromaffin-like cell carcinoids of gastric mucosa in rats after life-long inhibition of gastric secretion. Digestion (1986) 1.56
P450/losec. Gastroenterology (1991) 1.40
Total calories, body weight, and tumor incidence in mice. Cancer Res (1987) 1.39
Colon carcinogenesis with azoxymethane and dimethylhydrazine in germ-free rats. Cancer Res (1975) 1.35
Promotion of azoxymethane-induced colonic neoplasia by resection of the proximal small bowel. Cancer Res (1978) 1.31
Pentagastrin stimulates in vitro growth of normal and malignant human colon epithelial cells. Am J Surg (1985) 1.30
Clinical significance of gastrin receptors in human colon cancers. Cancer Res (1989) 1.27
Pathological features of the colonic tumours induced in rats by the administration of 1,2-dimethylhydrazine. Virchows Arch B Cell Pathol (1978) 1.26
Trophic effects of gastrin on colorectal neoplasms in the rat. Ann Surg (1982) 1.25
Growth-promoting action of gastrin on human colonic and gastric tumour cells cultured in vitro. Br J Surg (1988) 1.24
Gastrin stimulates growth of colon cancer. Surgery (1986) 1.24
Proglumide, a gastrin receptor antagonist, inhibits growth of colon cancer and enhances survival in mice. Ann Surg (1985) 1.22
Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer. Gastroenterology (1988) 1.19
Effect of long-term treatment with omeprazole on serum gastrin and serum group A and C pepsinogens in patients with reflux esophagitis. Gastroenterology (1990) 1.19
The in vitro growth response of primary human colorectal and gastric cancer cells to gastrin. Int J Cancer (1989) 1.19
Elevated gastrin levels in patients with colon cancer or adenomatous polyps. Dig Dis Sci (1989) 1.15
Co-stimulation of gastrointestinal tumour cell growth by gastrin, transforming growth factor alpha and insulin like growth factor-I. Br J Cancer (1991) 1.09
On the protective action of certain polycyclic aromatic hydrocarbons against carcinogenesis by aminoazo dyes and 2-acetylaminofluorene. Cancer Res (1958) 1.08
Gastrin receptors in normal and malignant gastrointestinal mucosa: age-associated changes. Am J Physiol (1985) 1.08
Intracellular gastrin in human gastrointestinal tumor cells. J Natl Cancer Inst (1991) 1.08
Postprandial hypergastrinaemia in patients with colorectal cancer. Gut (1991) 1.05
Measurement of gastrin and transforming growth factor alpha messenger RNA levels in colonic carcinoma cell lines by quantitative polymerase chain reaction. Cancer Res (1992) 1.04
Compensatory postresectional hyperplasia and starvation atrophy in small bowel: dissociation from endogenous gastrin levels. Gastroenterology (1977) 1.01
Hypergastrinemia and colorectal carcinogenesis in the rat. Cancer Lett (1985) 0.99
Radioimmunoassay of GI hormones. Clin Endocrinol Metab (1979) 0.96
Inhibitory effects of the gastrin receptor antagonist (L-365,260) on gastrointestinal tumor cells. Cancer (1991) 0.94
Trophic effect of gastrin on the enterochromaffin like cells of the rat stomach: establishment of a dose response relationship. Gut (1992) 0.92
Omeprazole and the induction of human cytochrome P-450: a response to concerns about potential adverse effects. Gastroenterology (1991) 0.91
Effect of different levels of calorie restriction on azoxymethane-induced colon carcinogenesis in male F344 rats. Cancer Res (1990) 0.90
Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1. Carcinogenesis (1991) 0.90
Inhibition of the carcinogenic action of benzo(a)pyrene by flavones. Cancer Res (1970) 0.89
Detection and characterization of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the human colon adenocarcinoma cell line LS180. Arch Biochem Biophys (1991) 0.88
Induction of cytochrome P-450IA1, IA2, IIB1, IIB2 and IIE1 by broccoli in rat liver and colon. Chem Biol Interact (1991) 0.87
Evaluation of the effects of pentagastrin, gastrin and pancreatic glucagon on cell proliferation in the rat gastrointestinal tract. Cell Tissue Kinet (1984) 0.86
Omeprazole-induced hypergastrinemia does not influence growth of colon carcinoma. Dig Dis Sci (1992) 0.86
Effect of omeprazole-induced hypergastrinaemia on the proliferation of colonic mucosal epithelial cells in the rat. Exp Clin Endocrinol (1991) 0.85
Enhancement and inhibition of the induction by 7,12-dimethylbenz(a)anthracene of mammary tumours in female Sprague-Dawley rats. Br J Cancer (1968) 0.85
Influence of caloric restriction and exercise on tumorigenesis in rats. Proc Soc Exp Biol Med (1990) 0.84
Tissue-specific induction of the carcinogen inducible cytochrome P450 isoform, P450IAI, in colonic epithelium. Arch Biochem Biophys (1991) 0.82
Serum gastrin concentrations in colorectal cancer patients. Ann R Coll Surg Engl (1992) 0.82
Expression of two cytochromes P450 involved in carcinogen activation in a human colon cell line. Mol Cell Biochem (1991) 0.82
The H+, K(+)-ATPase inhibitor pantoprazole (BY1023/SK&F96022) interacts less with cytochrome P450 than omeprazole and lansoprazole. Biochem Pharmacol (1991) 0.81
Dimethylhydrazine-induced colonic neoplasia: dissociation from endogenous gastrin levels. Surgery (1982) 0.80
Characterization of cytochrome P450-dependent dimethylhydrazine metabolism in human colon microsomes. Cancer (1991) 0.80
Gastrin has no promoting effect on chemically induced colonic tumors in Wistar rats. Eur J Cancer Clin Oncol (1985) 0.79
Modulation of the levels of cytochromes P450 in rat liver and lung by dietary lipid. Biochem Pharmacol (1992) 0.79
Influence of gastrin, gastrin receptor blockers, epidermal growth factor, and difluoromethylornithine on the growth and the activity of ornithine decarboxylase of colonic carcinoma cells. J Cancer Res Clin Oncol (1991) 0.79
Human cytochromes P450: evolution, catalytic activities and interindividual variations in expression. Prog Clin Biol Res (1991) 0.78
Protection against tumorigenesis by 3-methylcholanthrene in mice by beta-naphthoflavone as a function of inducibility of methylcholanthrene metabolism. Cancer Res (1985) 0.77
Role of gastrin/pentagastrin in regulation of intestinal cytochrome P-450. Comp Biochem Physiol C (1988) 0.76
Serum gastrin response to feeding in achlorhydric patients. Hepatogastroenterology (1980) 0.76
Effects of the food mutagens MeIQx and PhIP on the expression of cytochrome P450IA proteins in various tissues of male and female rats. Carcinogenesis (1990) 0.76
Human cytochrome P450 isoforms. Their genetic heterogeneity and induction by omeprazole. Gastroenterology (1990) 0.76
[Serum gastrin levels in colorectal cancers. Evolution after treatment]. Gastroenterol Clin Biol (1992) 0.76
Omeprazole, cytochrome P450, and chemical carcinogenesis. Gastroenterology (1992) 0.76
In vitro responsiveness of human gastric carcinoma to pentagastrin. Scand J Gastroenterol (1977) 0.76
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature (1996) 16.92
Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature (2000) 8.96
VEGF is required for growth and survival in neonatal mice. Development (1999) 6.16
Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis. Br J Cancer (2006) 4.93
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. Proc Natl Acad Sci U S A (1998) 3.73
Unbuffered highly acidic gastric juice exists at the gastroesophageal junction after a meal. Gastroenterology (2001) 3.52
Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature (2001) 3.42
Laparoscopic versus minilaparotomy cholecystectomy: a randomised trial. Lancet (1994) 3.29
Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology (1995) 3.28
High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc Natl Acad Sci U S A (1992) 3.22
Helicobacter pylori infection and chronic gastric acid hyposecretion. Gastroenterology (1997) 3.16
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer. Nature (1998) 2.98
Alosetron in irritable bowel syndrome. Lancet (2000) 2.94
Does concern about missing malignancy justify endoscopy in uncomplicated dyspepsia in patients aged less than 55? Am J Gastroenterol (1999) 2.89
Randomized clinical trial of the effect of postoperative intravenous fluid restriction on recovery after elective colorectal surgery. Br J Surg (2006) 2.66
Vascular endothelial growth factor is essential for corpus luteum angiogenesis. Nat Med (1998) 2.64
Surgical site infection after groin hernia repair. Br J Surg (2004) 2.54
Rebound hypersecretion after omeprazole and its relation to on-treatment acid suppression and Helicobacter pylori status. Gastroenterology (1999) 2.53
Outcome of patients with severe chronic pain following repair of groin hernia. Br J Surg (2002) 2.38
Expression of vascular endothelial growth factor, hypoxia inducible factor 1alpha, and carbonic anhydrase IX in human tumours. J Clin Pathol (2004) 2.36
The Helicobacter pylori breath test: a surrogate marker for peptic ulcer disease in dyspeptic patients. Gut (1997) 2.35
Comparison of manually constructed and stapled anastomoses in colorectal surgery. West of Scotland and Highland Anastomosis Study Group. Ann Surg (1995) 2.30
Five-year follow-up of a randomized trial to assess pain and numbness after laparoscopic or open repair of groin hernia. Br J Surg (2004) 2.20
The Glasgow Dyspepsia Severity Score--a tool for the global measurement of dyspepsia. Eur J Gastroenterol Hepatol (1996) 2.19
A case of a Spigelian hernia at an unusually high anatomical location. J R Coll Surg Edinb (2000) 2.18
Chronic groin sepsis following tension-free inguinal hernioplasty. Br J Surg (1999) 2.15
Phase I clinical trial design in cancer drug development. J Clin Oncol (2000) 2.14
Effect of a no-conversion policy on patient outcome following laparoscopic cholecystectomy. Br J Surg (1997) 2.13
Eradicating Helicobacter pylori infection lowers gastrin mediated acid secretion by two thirds in patients with duodenal ulcer. Gut (1993) 2.05
Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo. Prostate (1998) 2.02
Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1). Br J Cancer (2011) 1.99
Groin hernia repair in Scotland. Br J Surg (2000) 1.93
Bile duct injury and bile leakage in laparoscopic cholecystectomy. Br J Surg (1995) 1.87
Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res (1996) 1.86
Long-term follow-up of patients with a painless inguinal hernia from a randomized clinical trial. Br J Surg (2010) 1.83
Tin protoporphyrin prolongs the biochemical remission produced by heme arginate in acute hepatic porphyria. Gastroenterology (1993) 1.76
Controlled trial of haem arginate in acute hepatic porphyria. Lancet (1989) 1.75
Increased prevalence of precancerous changes in relatives of gastric cancer patients: critical role of H. pylori. Gastroenterology (2000) 1.74
The role of interleukin-1 polymorphisms in the pathogenesis of gastric cancer. Nature (2001) 1.71
Association between antibodies to heat shock protein 65 and coronary atherosclerosis. Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk. Eur Heart J (1998) 1.71
Laparoscopic colonic resection in fast-track patients does not enhance short-term recovery after elective surgery. Colorectal Dis (2007) 1.71
Lowered gastrin and gastric acidity after eradication of Campylobacter pylori in duodenal ulcer. Lancet (1989) 1.70
Preventing complications of laparoscopy. Br J Surg (1993) 1.70
Effect of closing dead space on seroma formation after mastectomy--a prospective randomized clinical trial. Eur J Surg Oncol (1993) 1.69
Paclitaxel and carboplatin in combination in the treatment of advanced non-small-cell lung cancer: a phase II toxicity, response, and survival analysis. J Clin Oncol (1995) 1.67
Effect of increasing Helicobacter pylori ammonia production by urea infusion on plasma gastrin concentrations. Gut (1991) 1.66
Acute perforated duodenal ulcer is not associated with Helicobacter pylori infection. Gut (1993) 1.64
Helicobacter pylori infection and coronary heart disease in the North Glasgow MONICA population. Eur Heart J (1997) 1.60
A randomized comparison of driver reaction time after open and endoscopic tension-free inguinal hernia repair. Surg Endosc (1999) 1.60
Plasma gastrin concentrations are normal in patients with colorectal neoplasia and unaltered following tumor resection. Gastroenterology (1994) 1.50
Helicobacter pylori infection potentiates the inhibition of gastric acid secretion by omeprazole. Gut (1999) 1.50
Phase I clinical and pharmacogenetic trial of irinotecan and raltitrexed administered every 21 days to patients with cancer. J Clin Oncol (2001) 1.50
Laparoscopic or minilaparotomy cholecystectomy? BMJ (1992) 1.50
Evaluation of the long term outcome of patients with extremity desmoids. Eur J Surg Oncol (2004) 1.48
Efficacy of tumoricidal agents in vitro and in vivo. Br J Surg (1995) 1.47
Value of biopsy in the assessment of a retroperitoneal mass. Surgeon (2006) 1.47
Randomized trial of different insufflation pressures for laparoscopic cholecystectomy. Br J Surg (1997) 1.47
Symptomatic outcome 1 year after laparoscopic and minilaparotomy cholecystectomy: a randomized trial. Br J Surg (1995) 1.44
Effect of suture material on tumour cell adherence at sites of colonic injury. Br J Surg (1993) 1.43
Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells. Br J Cancer (2005) 1.42
Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia. Mol Cell Biol (1994) 1.39
Laparoscopic and minilaparotomy cholecystectomy: a randomized trial comparing postoperative pain and pulmonary function. Surgery (1994) 1.38
Impact of video colonoscopy on stage and outcome of patients with symptomatic colorectal cancer. Surg Endosc (2004) 1.38
Randomized clinical trial comparing consultant-led or open access investigation for large bowel symptoms. Br J Surg (2003) 1.38
Comment on article by Oksüzoglu et al. Endoscopy (1998) 1.37
Hernias are the most common cause of strangulation in patients presenting with small bowel obstruction. Hernia (2006) 1.36
Comparison of gastric body and antral pH: a 24 hour ambulatory study in healthy volunteers. Gut (1989) 1.33
Omeprazole, Helicobacter pylori status, and alterations in the intragastric milieu facilitating bacterial N-nitrosation. Gastroenterology (2000) 1.33
Pain from primary inguinal hernia and the effect of repair on pain. Br J Surg (2002) 1.32
Positive lymph node retrieval ratio optimises patient staging in colorectal cancer. Br J Cancer (2009) 1.32
The role of laparoscopic adrenalectomy for adrenal tumours of 6 cm or greater. Surg Endosc (2007) 1.31
Detection of Helicobacter pylori infection of the gastric mucosa by measurement of gastric aspirate ammonium and urea concentrations. Gut (1991) 1.31
Treatment with haematin in acute hepatic porphyria. Q J Med (1981) 1.29
Low prevalence of Helicobacter pylori in inflammatory bowel disease: association with sulphasalazine. Gut (1994) 1.28
A study of the pathogenesis of Helicobacter pylori negative chronic duodenal ulceration. Gut (1993) 1.27
Helicobacter pylori utilises urea for amino acid synthesis. FEMS Immunol Med Microbiol (1996) 1.26
Etoposide (VP-16-213). Current status of an active anticancer drug. N Engl J Med (1985) 1.23
Rebound nocturnal hypersecretion after four weeks treatment with an H2 receptor antagonist. Gut (1989) 1.23
Early outcome after open versus extraperitoneal endoscopic tension-free hernioplasty: a randomized clinical trial. Surgery (1996) 1.21
Importance of VEGF for breast cancer angiogenesis in vivo: implications from intravital microscopy of combination treatments with an anti-VEGF neutralizing monoclonal antibody and doxorubicin. Anticancer Res (2000) 1.21
Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo. Cytokine (2001) 1.20
Effect of Helicobacter pylori and its eradication on gastric juice ascorbic acid. Gut (1994) 1.19
Induction of delta-aminolaevulinic acid synthase in leucocytes of patients on phenytoin therapy--comparison with changes in rat hepatic tissue. Br J Clin Pharmacol (1980) 1.19
Effects of cimetidine on carbamazepine auto- and hetero-induction in man. Br J Clin Pharmacol (1984) 1.19
Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2. J Cell Biol (1996) 1.19
The learning curve for laparoscopic hernia repair. Semin Laparosc Surg (1998) 1.18
Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia. Oncogene (2006) 1.17
The measurement of chronic pain and health-related quality of life following inguinal hernia repair: a review of the literature. Hernia (2008) 1.16
Anastomotic leaks in colorectal cancer surgery: a risk factor for recurrence? Int J Colorectal Dis (1991) 1.15
Screening for latent acute intermittent porphyria: the value of measuring both leucocyte delta-aminolaevulinic acid synthase and erythrocyte uroporphyrinogen-1-synthase activities. J Med Genet (1982) 1.15
Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif. J Immunol (1996) 1.15
Effect of Helicobacter pylori on parietal cell sensitivity to pentagastrin in duodenal ulcer subjects. Scand J Gastroenterol (1992) 1.14
Overexpression of HER2/neu in solid tumours: an immunohistochemical survey. Histopathology (2001) 1.13