The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy.

PubWeight™: 0.96‹?› | Rank: Top 15%

🔗 View Article (PMID 8269915)

Published in Epilepsy Res on October 01, 1993

Authors

S Sveinbjornsdottir1, J W Sander, D Upton, P J Thompson, P N Patsalos, D Hirt, M Emre, D Lowe, J S Duncan

Author Affiliations

1: National Society for Epilepsy, Institute of Neurology, Chalfont St. Peter, Bucks, UK.

Articles citing this

Removing obstacles in neuroscience drug discovery: the future path for animal models. Neuropsychopharmacology (2008) 2.16

Revisiting AMPA receptors as an antiepileptic drug target. Epilepsy Curr (2011) 1.98

Molecular targets for antiepileptic drug development. Neurotherapeutics (2007) 1.78

Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil. Br J Pharmacol (1994) 0.86

Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice. Front Cell Neurosci (2013) 0.85

Synaptic plasticity in glutamatergic and GABAergic neurotransmission following chronic memantine treatment in an in vitro model of limbic epileptogenesis. Neuropharmacology (2013) 0.83

Electrophysiological actions of felbamate on rat striatal neurones. Br J Pharmacol (1995) 0.79

Inverse relationship between seizure expression and extrasynaptic NMDAR function following chronic NMDAR inhibition. Epilepsia (2010) 0.78

In the picture: disulfide-poor conopeptides, a class of pharmacologically interesting compounds. J Venom Anim Toxins Incl Trop Dis (2016) 0.78

Synaptic and extrasynaptic plasticity in glutamatergic circuits involving dentate granule cells following chronic N-methyl-D-aspartate receptor inhibition. J Neurophysiol (2012) 0.77

A novel class of amino-alkylcyclohexanes as uncompetitive, fast, voltage-dependent, N-methyl-D-aspartate (NMDA) receptor antagonists--in vitro characterization. J Neural Transm (Vienna) (2007) 0.76

New developments in the treatment of partial-onset epilepsy. Neuropsychiatr Dis Treat (2012) 0.76

Animal Models of Seizures and Epilepsy: Past, Present, and Future Role for the Discovery of Antiseizure Drugs. Neurochem Res (2017) 0.76

Perampanel in the management of partial-onset seizures: a review of safety, efficacy, and patient acceptability. Patient Prefer Adherence (2015) 0.75

Perampanel: What is its Place in the Management of Partial Onset Epilepsy? Neurol Ther (2013) 0.75

Articles by these authors

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology (2005) 21.67

The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure. Can Med Assoc J (1985) 8.06

The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK. Brain (2000) 4.76

Effect of encouragement on walking test performance. Thorax (1984) 4.44

Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study. Lancet (2000) 4.37

Mortality from epilepsy: results from a prospective population-based study. Lancet (1994) 4.31

Patient-to-patient transmission of HIV in private surgical consulting rooms. Lancet (1994) 4.12

Mild cognitive impairment in Parkinson disease: a multicenter pooled analysis. Neurology (2010) 4.06

Effect of ultraclean air in operating rooms on deep sepsis in the joint after total hip or knee replacement: a randomised study. Br Med J (Clin Res Ed) (1982) 3.71

Vigabatrin and behaviour disturbances. Lancet (1990) 3.30

Remission of epilepsy: results from the National General Practice Study of Epilepsy. Lancet (1995) 3.17

DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers. Neurology (2007) 2.86

Segmentation and measurement of the cortex from 3-D MR images using coupled-surfaces propagation. IEEE Trans Med Imaging (1999) 2.85

Epilepsy in a population of 6000 re-examined: secular trends in first attendance rates, prevalence, and prognosis. J Neurol Neurosurg Psychiatry (1995) 2.84

Access to stroke care in England, Wales and Northern Ireland: the effect of age, gender and weekend admission. Age Ageing (2007) 2.80

Drowning in people with epilepsy: how great is the risk? Neurology (2008) 2.80

National General Practice Study of Epilepsy: recurrence after a first seizure. Lancet (1990) 2.65

Evidence for a link between mortality in acute COPD and hospital type and resources. Thorax (2003) 2.63

How should we measure function in patients with chronic heart and lung disease? J Chronic Dis (1985) 2.61

Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions. J Clin Invest (1999) 2.53

Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline. Eur J Neurol (2007) 2.47

Hydrofluoroalkane-134a beclomethasone dipropionate, 400 microg, is as effective as chlorofluorocarbon beclomethasone dipropionate, 800 microg, for the treatment of moderate asthma. Chest (1999) 2.38

Acidosis, non-invasive ventilation and mortality in hospitalised COPD exacerbations. Thorax (2010) 2.38

Comprehensive primary health care antiepileptic drug treatment programme in rural and semi-urban Kenya. ICBERG (International Community-based Epilepsy Research Group) Lancet (1991) 2.36

Augmentation of permeability in the bronchial epithelium by the house dust mite allergen Der p1. Am J Respir Cell Mol Biol (1995) 2.30

Neurocysticercosis and epilepsy in developing countries. J Neurol Neurosurg Psychiatry (2000) 2.28

Incidence and prevalence studies in epilepsy and their methodological problems: a review. J Neurol Neurosurg Psychiatry (1987) 2.25

Tissue artefacts caused by sponges. J Clin Pathol (1992) 2.23

Clinical audit indicators of outcome following admission to hospital with acute exacerbation of chronic obstructive pulmonary disease. Thorax (2002) 2.22

Airborne contamination of wounds in joint replacement operations: the relationship to sepsis rates. J Hosp Infect (1983) 2.20

Surgical outcome in patients with epilepsy and dual pathology. Brain (1999) 2.19

Case-control study of SUDEP. Neurology (2005) 2.11

The treatment gap in epilepsy: the current situation and ways forward. Epilepsia (2001) 2.10

IL-10, T lymphocyte inhibitor of human blood cell production of IL-1 and tumor necrosis factor. J Immunol (1992) 2.09

Tonsillectomy technique as a risk factor for postoperative haemorrhage. Lancet (2004) 2.08

Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI. Brain (1999) 2.08

Detection of hippocampal pathology in intractable partial epilepsy: increased sensitivity with quantitative magnetic resonance T2 relaxometry. Neurology (1993) 2.04

Tumour-associated eosinophilia: a review. J Clin Pathol (1981) 2.03

A comparison of outcomes for patients with oral squamous cell carcinoma at intermediate risk of recurrence treated by surgery alone or with post-operative radiotherapy. Oral Oncol (2006) 2.01

Outcomes of rescue therapy in acute severe ulcerative colitis: data from the United Kingdom inflammatory bowel disease audit. Aliment Pharmacol Ther (2013) 2.01

The treatment of epilepsy in developing countries: where do we go from here? Bull World Health Organ (2003) 2.00

Periventricular heterotopia: phenotypic heterogeneity and correlation with Filamin A mutations. Brain (2006) 2.00

The national sentinel audit for stroke: a tool for raising standards of care. J R Coll Physicians Lond (2000) 1.97

Validation of a screening questionnaire for the detection of epileptic seizures in epidemiological studies. Brain (1992) 1.94

Characterization of factors that direct transcription of rat ribosomal DNA. Mol Cell Biol (1990) 1.93

Audit of acute admissions of COPD: standards of care and management in the hospital setting. Eur Respir J (2001) 1.90

Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy. J Neurol Neurosurg Psychiatry (1996) 1.89

Model-based deformable surface finding for medical images. IEEE Trans Med Imaging (1996) 1.89

Diagnosis and management of Alzheimer's disease and other disorders associated with dementia. The role of neurologists in Europe. European Federation of Neurological Societies. Eur J Neurol (2000) 1.89

UK National COPD Audit 2003: Impact of hospital resources and organisation of care on patient outcome following admission for acute COPD exacerbation. Thorax (2006) 1.89

EEG-triggered functional MRI of interictal epileptiform activity in patients with partial seizures. Brain (1999) 1.88

Infection and sepsis after operations for total hip or knee-joint replacement: influence of ultraclean air, prophylactic antibiotics and other factors. J Hyg (Lond) (1984) 1.85

Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing. Br J Cancer (2006) 1.84

Efficacy assessment of phenobarbital in epilepsy: a large community-based intervention trial in rural China. Lancet Neurol (2006) 1.83

Cervical lymph node metastasis in oral cancer: the importance of even microscopic extracapsular spread. Oral Oncol (2003) 1.81

Effects of topiramate on cognitive function. J Neurol Neurosurg Psychiatry (2000) 1.81

Mutations in the X-linked filamin 1 gene cause periventricular nodular heterotopia in males as well as in females. Hum Mol Genet (2001) 1.80

Stroke units: research and reality. Results from the National Sentinel Audit of Stroke. Qual Saf Health Care (2005) 1.80

Deformable boundary finding in medical images by integrating gradient and region information. IEEE Trans Med Imaging (1996) 1.80

The prevalence of aspirin intolerant asthma (AIA) in Australian asthmatic patients. Thorax (2002) 1.80

Rifampicin reduces effectiveness and bioavailability of prednisolone. Br Med J (Clin Res Ed) (1983) 1.79

Causes of death among people with convulsive epilepsy in rural West China: a prospective study. Neurology (2011) 1.77

The psychiatric comorbidity of epilepsy. Acta Neurol Scand (2004) 1.77

Accurate alignment of functional EPI data to anatomical MRI using a physics-based distortion model. IEEE Trans Med Imaging (2000) 1.75

Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium. J Immunol (1998) 1.73

Sudden unexpected deaths in epilepsy--where are we now? Seizure (1996) 1.73

Benign and malignant teratomas in children: analysis of 85 patients. Surgery (1976) 1.71

Long-term use of lamotrigine and vigabatrin in severe refractory epilepsy: audit of outcome. BMJ (1996) 1.70

Incidence of epilepsy: a systematic review and meta-analysis. Neurology (2011) 1.68

Improvement of stiff-man syndrome with vigabatrin. Neurology (1997) 1.68

Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta. Proc Natl Acad Sci U S A (1997) 1.67

Neuropsychiatric symptoms in patients with Parkinson's disease and dementia: frequency, profile and associated care giver stress. J Neurol Neurosurg Psychiatry (2006) 1.67

The prevalence and treatment gap in epilepsy in China: an ILAE/IBE/WHO study. Neurology (2003) 1.66

Malignant eccrine poroma: a study of twenty-seven cases. Br J Dermatol (1982) 1.66

Generation of a humanized, high affinity anti-tissue factor antibody for use as a novel antithrombotic therapeutic. Thromb Haemost (2001) 1.64

Mortality in patients with epilepsy: a study of patients in long term residential care. J Neurol Neurosurg Psychiatry (1993) 1.64

Intra-prostatic urinary reflux: an aetiological factor in abacterial prostatitis. Br J Urol (1982) 1.64

The spectrum of hippocampal sclerosis: a quantitative magnetic resonance imaging study. Ann Neurol (1997) 1.63

Automatic segmentation of the hippocampus and the amygdala driven by hybrid constraints: method and validation. Neuroimage (2009) 1.63

A randomised trial of peer review: the UK National Chronic Obstructive Pulmonary Disease Resources and Outcomes Project. Clin Med (2010) 1.62

National stroke audit: a tool for change? Qual Health Care (2001) 1.61

Diffusion tensor imaging in patients with epilepsy and malformations of cortical development. Brain (2001) 1.60

Corpora amylacea in hippocampal sclerosis. J Neurol Neurosurg Psychiatry (1997) 1.60

Presurgical evaluation of patients with epilepsy and normal MRI: role of scalp video-EEG telemetry. J Neurol Neurosurg Psychiatry (1999) 1.59

Incidence of sudden unexpected death in an adult outpatient cohort with epilepsy at a tertiary referral centre. J Neurol Neurosurg Psychiatry (1995) 1.58

A longitudinal study of brain morphometrics using quantitative magnetic resonance imaging and difference image analysis. Neuroimage (2003) 1.58

Optimizing the diagnosis of hippocampal sclerosis using MR imaging. AJNR Am J Neuroradiol (1993) 1.57

Unilateral temporal lobectomy patients show lateralized topographical and episodic memory deficits in a virtual town. Brain (2001) 1.57

Mortality in epilepsy in the first 11 to 14 years after diagnosis: multivariate analysis of a long-term, prospective, population-based cohort. Ann Neurol (2001) 1.56

Epilepsy: getting the diagnosis right. BMJ (1997) 1.56

Nonphotosynthetic retardation of chloroplast senescence by light. Plant Physiol (1969) 1.55

A novel tissue inhibitor of metalloproteinase-1 (TIMP-1) polymorphism associated with asthma in Australian women. Thorax (2005) 1.55

Oxidant stress induces gamma-glutamylcysteine synthetase and glutathione synthesis in human bronchial epithelial NCI-H292 cells. Clin Exp Allergy (2002) 1.55

Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma. J Allergy Clin Immunol (2001) 1.55

Predictors of speech and swallowing function following primary surgery for oral and oropharyngeal cancer. Clin Otolaryngol (2005) 1.55

The biochemistry of common aeroallergens. Clin Exp Allergy (1996) 1.54

Benzodiazepine receptor quantification in vivo in humans using [11C]flumazenil and PET: application of the steady-state principle. J Cereb Blood Flow Metab (1995) 1.54

Clinical features of convulsive status epilepticus: a study of 220 cases in western China. Eur J Neurol (2009) 1.53