Published in Ann Intern Med on April 01, 1993
Genetic Response to Warfarin in Healthy Subjects | NCT01520402
Use of warfarin in non-rheumatic atrial fibrillation: a commentary from general practice. Br J Gen Pract (1995) 6.43
An evidence based approach to individualising treatment. BMJ (1995) 5.10
Comparing the quality of oral anticoagulant management by anticoagulation clinics and by family physicians: a randomized controlled trial. CMAJ (2003) 3.73
Anticoagulation therapy for venous thromboembolism. MedGenMed (2004) 3.61
Warfarin use associates with increased risk for stroke in hemodialysis patients with atrial fibrillation. J Am Soc Nephrol (2009) 3.40
Influence of CYP2C9 and VKORC1 1173C/T genotype on the risk of hemorrhagic complications in African-American and European-American patients on warfarin. Clin Pharmacol Ther (2007) 2.54
Warfarin pharmacogenetics. Pharmacotherapy (2008) 2.50
A test of financial incentives to improve warfarin adherence. BMC Health Serv Res (2008) 2.23
Kidney function influences warfarin responsiveness and hemorrhagic complications. J Am Soc Nephrol (2009) 2.13
Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy. Blood (2008) 1.99
Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans. Pharmacogenomics (2008) 1.89
Genetic testing before anticoagulation? A systematic review of pharmacogenetic dosing of warfarin. J Gen Intern Med (2009) 1.77
Achieved anticoagulation vs prosthesis selection for mitral mechanical valve replacement: a population-based outcome study. Chest (2009) 1.39
Genetics informatics trial (GIFT) of warfarin to prevent deep vein thrombosis (DVT): rationale and study design. Pharmacogenomics J (2011) 1.38
Risk of major hemorrhage for outpatients treated with warfarin. J Gen Intern Med (1998) 1.36
Warfarin reversal. J Clin Pathol (2004) 1.33
Is INR between 2.0 and 3.0 the optimal level for Chinese patients on warfarin therapy for moderate-intensity anticoagulation? Br J Clin Pharmacol (2005) 1.29
Family planning requirements in the adult congenital heart disease clinic. Heart (1996) 1.21
Cerebral microbleeds on magnetic resonance imaging and anticoagulant-associated intracerebral hemorrhage risk. Front Neurol (2012) 1.14
A new regimen for starting warfarin therapy in out-patients. Br J Clin Pharmacol (1998) 1.12
Does the Birmingham model of oral anticoagulation management in primary care work outside trial conditions? Br J Gen Pract (2001) 1.06
Influence of decision aids on patient preferences for anticoagulant therapy: a randomized trial. CMAJ (2007) 1.03
Influence of CYP2C9 and VKORC1 on warfarin response during initiation of therapy. Blood Cells Mol Dis (2009) 1.02
The cost-effectiveness of different management strategies for patients on chronic warfarin therapy. J Gen Intern Med (2000) 1.02
Polypharmacy is associated with an increased risk of bleeding in elderly patients with venous thromboembolism. J Gen Intern Med (2014) 1.02
Management of Chinese patients on warfarin therapy in two models of anticoagulation service - a prospective randomized trial. Br J Clin Pharmacol (2006) 1.02
Costs and effectiveness of a nurse specialist anticoagulant service. J Clin Pathol (1997) 0.99
Improving chronic illness care for veterans within the framework of the Patient-Centered Medical Home: experiences from the Ann Arbor Patient-Aligned Care Team Laboratory. Transl Behav Med (2011) 0.95
Understanding the pharmacogenetic approach to warfarin dosing. Heart Fail Rev (2008) 0.94
SMART: self-management of anticoagulation, a randomised trial [ISRCTN19313375]. BMC Fam Pract (2003) 0.93
Pharmacogenomic progress in individualized dosing of key drugs for cancer patients. Nat Clin Pract Oncol (2009) 0.92
Alcohol intake and noncoronary cardiovascular diseases. Ann Epidemiol (2007) 0.92
Should we test for CYP2C9 before initiating anticoagulant therapy in patients with atrial fibrillation? J Gen Intern Med (2009) 0.90
Patient reported receipt of medication instructions for warfarin is associated with reduced risk of serious bleeding events. J Gen Intern Med (2008) 0.89
Genotype and risk of major bleeding during warfarin treatment. Pharmacogenomics (2014) 0.88
The influence of age, liver size and enantiomer concentrations on warfarin requirements. Br J Clin Pharmacol (1995) 0.87
Antithrombotic medication for cardioembolic stroke prevention. Stroke Res Treat (2011) 0.87
Influence of kidney function on risk of hemorrhage among patients taking warfarin: a cohort study. Am J Kidney Dis (2012) 0.87
Bench-to-bedside review: Optimising emergency reversal of vitamin K antagonists in severe haemorrhage - from theory to practice. Crit Care (2009) 0.86
Anticoagulation Management as a Risk Factor for Adverse Events: Grounds for Improvement. J Thromb Thrombolysis (1998) 0.86
Prospective pilot trial of PerMIT versus standard anticoagulation service management of patients initiating oral anticoagulation. Thromb Haemost (2012) 0.85
Pharmacogenetics of anticoagulants. Hum Genomics Proteomics (2010) 0.84
Genetic and environmental risk factors for oral anticoagulant overdose. Eur J Clin Pharmacol (2003) 0.83
Diet as prophylaxis and treatment for venous thromboembolism? Theor Biol Med Model (2010) 0.83
External quality assessment for warfarin dosing using computerised decision support software. J Clin Pathol (2003) 0.83
Association between CHADS₂risk factors and anticoagulation-related bleeding: a systematic literature review. Mayo Clin Proc (2011) 0.83
Acute upper gastrointestinal bleeding in patients on long-term oral anticoagulation therapy: endoscopic findings, clinical management and outcome. World J Gastroenterol (2005) 0.82
Anticoagulation control in the peri-hospitalization period. J Gen Intern Med (2007) 0.82
Anticoagulation and atrial fibrillation. Putting the results of clinical trials into practice. West J Med (1995) 0.81
Influence of kidney function on risk of supratherapeutic international normalized ratio-related hemorrhage in warfarin users: a prospective cohort study. Am J Kidney Dis (2014) 0.80
CYP2C9 genotypes and the quality of anticoagulation control with warfarin therapy among Brazilian patients. Eur J Clin Pharmacol (2007) 0.80
The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements in an adult Turkish population. Heart Vessels (2010) 0.80
Predictors of warfarin-induced bleeding in a South Indian cardiology unit. Perspect Clin Res (2012) 0.78
Experience with INR self-management: patient selection and complication rates. Z Kardiol (2005) 0.78
Influence of regular physical activity on warfarin dose and risk of hemorrhagic complications. Pharmacotherapy (2014) 0.78
Factors affecting time to maintenance dose in patients initiating warfarin. Pharmacoepidemiol Drug Saf (2014) 0.77
CYP4F2 polymorphism as a genetic risk factor for major hemorrhagic complications in Chinese patients on warfarin therapy. J Geriatr Cardiol (2012) 0.77
Outpatient management of oral anticoagulation therapy in patients with nonvalvular atrial fibrillation. Bosn J Basic Med Sci (2009) 0.77
Evidence-based medicine and the Cochrane Collaboration on trial. MedGenMed (2007) 0.76
Pharmacogenetic association study of warfarin safety endpoints in Puerto Ricans. P R Health Sci J (2014) 0.76
Serious bleeding events due to warfarin and antibiotic co-prescription in a cohort of veterans. Am J Med (2014) 0.76
Clinical application of a new warfarin-dosing regimen based on the CYP2C9 and VKORC1 genotypes in atrial fibrillation patients. Biomed Rep (2016) 0.75
Antithrombotic therapy in cardiac embolism. Curr Cardiol Rev (2010) 0.75
Objectives and Design of BLEEDS: A Cohort Study to Identify New Risk Factors and Predictors for Major Bleeding during Treatment with Vitamin K Antagonists. PLoS One (2016) 0.75
Predicting prolonged dose titration in patients starting warfarin. Pharmacoepidemiol Drug Saf (2016) 0.75
A role for pharmacists in community-based post-discharge warfarin management: protocol for the 'the role of community pharmacy in post hospital management of patients initiated on warfarin' study. BMC Health Serv Res (2011) 0.75
Using highly variable warfarin dosing to identify patients at risk for adverse events. Thromb J (2011) 0.75
Warfarin pharmacogenetics: does more accurate dosing benefit patients? Semin Thromb Hemost (2012) 0.75
A systematic review of Cochrane anticoagulation reviews. Medscape J Med (2009) 0.75
Incidence and predictors of excessive warfarin anticoagulation in patients with atrial fibrillation-The EWA study. PLoS One (2017) 0.75
Dialysis access thrombosis in a family cohort. J Natl Med Assoc (2007) 0.75
Managing anticoagulation safely. Ann Intern Med (1993) 0.75
An Audit of Management of Patients on Oral Anticoagulant Therapy With International Normalized Ratio (INR) Five or Above. Indian J Hematol Blood Transfus (2012) 0.75
Spontaneous and non-spontaneous bleeding complications in patients with oral vitamin K antagonist therapy. Langenbecks Arch Surg (2013) 0.75
Impact of intraoperative blood loss on morbidity and survival after radical surgery for colorectal cancer patients aged 80 years or older. Int J Colorectal Dis (2015) 0.75
Development and evaluation of the Seattle Angina Questionnaire: a new functional status measure for coronary artery disease. J Am Coll Cardiol (1995) 7.64
Changes in plasma HIV-1 RNA and CD4+ lymphocyte counts and the risk of progression to AIDS. Veterans Affairs Cooperative Study Group on AIDS. N Engl J Med (1996) 7.06
Control of specific gene expression in higher organisms. Expression of mammalian genes may be controlled by repressors acting on the translation of messenger RNA. Science (1969) 4.81
Deprivation payments to general practitioners: limitations of census data. BMJ (1996) 3.98
The risk for and severity of bleeding complications in elderly patients treated with warfarin. The National Consortium of Anticoagulation Clinics. Ann Intern Med (1996) 3.79
Pathology of the nephrotic syndrome in children: a report for the International Study of Kidney Disease in Children. Lancet (1970) 3.78
Using data from the 1991 census. BMJ (1995) 3.63
Cysteine desulfurase activity indicates a role for NIFS in metallocluster biosynthesis. Proc Natl Acad Sci U S A (1993) 3.59
Guidelines on the management of common bile duct stones (CBDS). Gut (2008) 3.58
Early predictors of career achievement in academic medicine. JAMA (1992) 3.35
Clinicopathological study of nephrotic syndrome in childhood. Lancet (1970) 3.13
emm typing and validation of provisional M types for group A streptococci. Emerg Infect Dis (1999) 3.12
Urine microscopy as an aid to detection of bacteriuria. Lancet (1975) 3.09
A prospective study of delirium in hospitalized elderly. JAMA (1990) 3.02
The Index of Multiple Deprivation 2000 and accessibility effects on health. J Epidemiol Community Health (2004) 2.92
Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study. Endoscopy (2007) 2.88
Duodenal and gastric ulcer prevention with misoprostol in arthritis patients taking NSAIDs. Misoprostol Study Group. Ann Intern Med (1993) 2.74
Schönlein-Henoch nephritis. Q J Med (1972) 2.64
Preventing disability and managing chronic illness in frail older adults: a randomized trial of a community-based partnership with primary care. J Am Geriatr Soc (1998) 2.62
Management of urinary tract infection. Arch Dis Child (1987) 2.57
Haemolytic-uraemic syndrome: clinical experience of an outbreak in the West Midlands. Br Med J (Clin Res Ed) (1986) 2.47
Postcodes and the 1991 census of population: issues, problems and prospects. Trans Inst Br Geogr (1992) 2.46
On-site HIV testing in resource-poor settings: is one rapid test enough? AIDS (1997) 2.39
Management and dosing of warfarin therapy. Am J Med (2000) 2.36
Functional recovery in parkinsonian monkeys treated with GDNF. Nature (1996) 2.35
Estrogen therapy and variable-resistance weight training increase bone mineral in surgically menopausal women. J Bone Miner Res (1991) 2.33
Prognosis of Henoch-Schönlein nephritis in children. Br Med J (1977) 2.32
Immunosuppressive therapy in steroid-resistant proliferative glomerulonephritis accompanied by the nephrotic syndrome. Br Med J (1966) 2.31
Mechanism for the desulfurization of L-cysteine catalyzed by the nifS gene product. Biochemistry (1994) 2.26
Patient outcomes after lumbar spinal fusions. JAMA (1992) 2.14
Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient mice. J Exp Med (1993) 2.07
Intrathecal HIV-1 envelope glycoprotein gp120 induces enhanced pain states mediated by spinal cord proinflammatory cytokines. J Neurosci (2001) 2.07
Prevalence of symptomless urinary tract disease in Birmingham schoolchildren. I. Pyuria and bacteriuria. Br Med J (1969) 2.01
Cyclophosphamide therapy in the nephrotic syndrome in childhood. Br Med J (1969) 1.99
Transforming self-rated health and the SF-36 scales to include death and improve interpretability. Med Care (2001) 1.99
Difficulties in recognizing one's own incompetence: novice physicians who are unskilled and unaware of it. Acad Med (2001) 1.98
The running tie-over dressing. Plast Reconstr Surg (2000) 1.96
Synthesis and induction of tyrosine aminotransferase in synchronized hepatoma cells in culture. Proc Natl Acad Sci U S A (1969) 1.95
Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic pain. Neuroscience (2001) 1.91
Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat. Pain (1997) 1.90
Gastrointestinal hormone responses to meals before and after gastric bypass and vertical banded gastroplasty. Ann Surg (1990) 1.90
Terpenoid secondary metabolism in Arabidopsis thaliana: cDNA cloning, characterization, and functional expression of a myrcene/(E)-beta-ocimene synthase. Arch Biochem Biophys (2000) 1.89
Isolation of eastern equine encephalitis virus from Aedes albopictus in Florida. Science (1992) 1.89
A novel mechanism for skeletal resistance in uremia. Kidney Int (2000) 1.88
Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120. Brain Res (2000) 1.83
Tight junction proteins ZO-1, ZO-2, and occludin along isolated renal tubules. Kidney Int (2000) 1.82
Comorbidity in ADHD: implications for research, practice, and DSM-V. J Am Acad Child Adolesc Psychiatry (1997) 1.81
Transcriptional regulation of the mosquito vitellogenin gene via a blood meal-triggered cascade. Gene (2001) 1.81
Membranous nephropathy. Long-term follow-up and association with neoplasia. Q J Med (1975) 1.81
Linking community-based blood pressure measurement to clinical care: a randomized controlled trial of outreach and tracking by community health workers. Am J Public Health (1999) 1.81
Characterization of cytokine-induced hyperalgesia. Brain Res (1994) 1.78
Establishing a workplace antiretroviral therapy programme in South Africa. AIDS Care (2007) 1.75
Identification of group B streptococcal Sip protein, which elicits cross-protective immunity. Infect Immun (2000) 1.73
A multilevel analysis of the effects of rurality and social deprivation on premature limiting long term illness. J Epidemiol Community Health (2001) 1.72
Immunogenicity and safety of a strain-specific MenB OMV vaccine delivered to under 5-year olds in New Zealand. Vaccine (2007) 1.72
Occurrence of S-methyl thioesters in urines of humans after they have eaten asparagus. Science (1975) 1.69
Lipopolysaccharide pre-treatment induces resistance against subsequent focal cerebral ischemic damage in spontaneously hypertensive rats. Brain Res (1997) 1.69
What predicts failed cannulation and therapy at ERCP? Results of a large-scale multicenter analysis. Endoscopy (2012) 1.68
Misoprostol compared with sucralfate in the prevention of nonsteroidal anti-inflammatory drug-induced gastric ulcer. A randomized, controlled trial. Ann Intern Med (1991) 1.68
Comprehensive microRNA expression profiling of the hematopoietic hierarchy. Proc Natl Acad Sci U S A (2010) 1.67
Issues in the measurement of satisfaction with treatment. Am J Manag Care (1997) 1.67
Neisseria meningitidis group B correlates of protection and assay standardization--international meeting report Emory University, Atlanta, Georgia, United States, 16-17 March 2005. Vaccine (2006) 1.67
Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen. J Clin Invest (1996) 1.64
Clinical significance of antenatal calyceal dilatation detected by ultrasound. Lancet (1990) 1.64
Recognition and management of fatty acid oxidation defects: a series of 107 patients. J Inherit Metab Dis (1999) 1.63
Antimicrobial prophylaxis of recurrent urinary tract infections: a double-blind, placebo-controlled trial. Ann Intern Med (1980) 1.61
Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction. Am J Physiol Renal Physiol (2000) 1.61
Symptomless haematuria in childhood. Br Med J (1970) 1.61
Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: evidence for vagal mediation of immune-brain communication. Neurosci Lett (1995) 1.60
Expanded polytetrafluoroethylene as a substrate for retinal pigment epithelial cell growth and transplantation in age-related macular degeneration. Br J Ophthalmol (2011) 1.60
Position-dependent variegation of globin transgene expression in mice. Proc Natl Acad Sci U S A (1995) 1.58
The generation of spatial population distributions from census centroid data. Environ Plan A (1989) 1.57
Arrhythmias and conduction defects as presenting symptoms of fatty acid oxidation disorders in children. Circulation (1999) 1.57
Association between depression and worse disease-specific functional status in outpatients with coronary artery disease. Am Heart J (2000) 1.56
Stable isotope studies on the biosynthesis of lipoic acid in Escherichia coli. Biochemistry (1980) 1.56
Meningococcal disease in Auckland, July 1992 - June 1994. N Z Med J (1999) 1.55
Acute intraoperative suprachoroidal haemorrhage in ocular surgery. Eye (Lond) (1998) 1.55
The incidence of venous thromboembolism among patients with primary lung cancer. J Thromb Haemost (2008) 1.55
The effect of calcitriol, paricalcitol, and a calcimimetic on extraosseous calcifications in uremic rats. Kidney Int (2007) 1.53
Protein trans-splicing and cyclization by a naturally split intein from the dnaE gene of Synechocystis species PCC6803. J Biol Chem (2000) 1.53
Quartan malarial nephrotic syndrome. Collaborative clinicopathological study in Nigerian children. Lancet (1972) 1.52
Japanese encephalitis among hospitalized pediatric and adult patients with acute encephalitis syndrome in Hanoi, Vietnam 1995. Am J Trop Med Hyg (1998) 1.52
Long-term outcome for children with minimal-change nephrotic syndrome. Lancet (1985) 1.52
Linkage of the 1981 and 1991 U.K. censuses using surface modelling concepts. Environ Plan A (1995) 1.52
Cholera on the Texas Gulf Coast. JAMA (1982) 1.50
Renal biopsy diagnosis in children presenting with haematuria. Pediatr Nephrol (1998) 1.49
Recent immigration and the misery of motherhood: a discussion of pertinent issues. Midwifery (1998) 1.48
Tenm, a Drosophila gene related to tenascin, is a new pair-rule gene. EMBO J (1994) 1.48
Coexistence of thin membrane and alport nephropathies in families with haematuria. Pediatr Nephrol (1999) 1.48
Long-term follow-up of childhood Henoch-Schönlein nephritis. Lancet (1992) 1.47
Identification of methyl coenzyme M as an intermediate in methanogenesis from acetate in Methanosarcina spp. J Bacteriol (1984) 1.47
A randomized trial of misoprostol and oxytocin for induction of labor: safety and efficacy. Obstet Gynecol (1997) 1.47
Computer-assisted dosing of heparin. Management with a pharmacy-based anticoagulation service. Arch Intern Med (1994) 1.46
Fatal shoulder dystocia: a review of 56 cases reported to the Confidential Enquiry into Stillbirths and Deaths in Infancy. Br J Obstet Gynaecol (1998) 1.46
Esophageal symptoms, manometry, and histology before and after antireflux surgery: a long-term follow-up study. Gastroenterology (1979) 1.46
Clinical intestinal transplantation: a decade of experience at a single center. Ann Surg (2001) 1.44
Residual vein obstruction as a predictor for recurrent thromboembolic events after a first unprovoked episode: data from the REVERSE cohort study. J Thromb Haemost (2011) 1.42
Cytotoxic drug therapy in steroid-resistant glomerulonephritis. Proc R Soc Med (1967) 1.42
Argon laser trabecular surgery in uncontrolled phakic open angle glaucoma. Ophthalmology (1981) 1.42