Published in Eur J Immunol on February 01, 1994
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity (2008) 6.08
Transfer of human serum IgG to nonobese diabetic Igmu null mice reveals a role for autoantibodies in the loss of secretory function of exocrine tissues in Sjögren's syndrome. Proc Natl Acad Sci U S A (1998) 1.55
Elevated levels of cysteine protease activity in saliva and salivary glands of the nonobese diabetic (NOD) mouse model for Sjögren syndrome. Proc Natl Acad Sci U S A (1997) 1.15
Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis. Mol Biol Cell (2003) 1.14
Apoptosis resistance of nonobese diabetic peripheral lymphocytes linked to the Idd5 diabetes susceptibility region. Proc Natl Acad Sci U S A (1997) 0.98
Genes within the Idd5 and Idd9/11 diabetes susceptibility loci affect the pathogenic activity of B cells in nonobese diabetic mice. J Immunol (2006) 0.95
Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis. Am J Hum Genet (2000) 0.91
A novel multimeric form of FasL modulates the ability of diabetogenic T cells to mediate type 1 diabetes in an adoptive transfer model. Mol Immunol (2007) 0.90
The role of the innate immune system in granulomatous disorders. Front Immunol (2013) 0.89
1,25-Dihydroxyvitamin D3 restores sensitivity to cyclophosphamide-induced apoptosis in non-obese diabetic (NOD) mice and protects against diabetes. Clin Exp Immunol (1998) 0.85
Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background. J Autoimmun (2013) 0.82
Involvement of c-myc in the resistance of non-obese diabetic mice to glucocorticoid-induced apoptosis. Immunology (1998) 0.81
Assay for high glucose-mediated islet cell sensitization to apoptosis induced by streptozotocin and cytokines. Biol Proced Online (2005) 0.79
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature (1996) 8.02
In vivo specific antigen recognition by rosette forming cells. Nature (1970) 4.78
In vitro evaluation of immunosuppressive drugs. Nature (1969) 4.70
Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells. J Exp Med (1987) 4.38
Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc Natl Acad Sci U S A (1994) 3.77
Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients. Lancet (1997) 3.68
Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat Med (2001) 3.56
Detection of circulating immune complexes in human sera by simplified assays with polyethylene glycol. J Immunol Methods (1977) 3.24
Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone. Proc Natl Acad Sci U S A (1971) 3.13
In vitro rosette inhibition by antihuman antilymphocyte serum. Correlation with skin graft prolongation in subhuman primates. Transplantation (1969) 3.12
CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J Immunol (1997) 2.89
Truncating mutations in CCM1, encoding KRIT1, cause hereditary cavernous angiomas. Nat Genet (1999) 2.79
Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes. J Exp Med (1998) 2.75
T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice. J Exp Med (1989) 2.51
Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse. Eur J Immunol (1996) 2.43
The key role of nucleosomes in lupus. Arthritis Rheum (1999) 2.26
A sequential model for peptide binding and transport by the transporters associated with antigen processing. Immunity (1994) 2.26
A new in vitro test evaluating anti-lymphocyte serum potency. Transplant Proc (1969) 2.21
Studies on thymus products. II. Demonstration and characterization of a circulating thymic hormone. Immunology (1973) 2.17
Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma. Hum Mol Genet (1997) 2.08
Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: further evidence for transient in vivo T cell activation. Eur J Immunol (1990) 1.96
Studies on thymus products. IV. Absence of serum 'thymic activity' in adult NZB and (NZB x NZW) F1 mice. Clin Exp Immunol (1973) 1.93
Isolation, biochemical characteristics, and biological activity of a circulating thymic hormone in the mouse and in the human. Ann N Y Acad Sci (1975) 1.89
Establishment and characterization of a murine hybridoma secreting monoclonal anti-DNA autoantibody. J Immunol (1980) 1.88
Anti-suppressor effect of cyclophosphamide on the development of spontaneous diabetes in NOD mice. Eur J Immunol (1988) 1.87
Evaluation of T-cells and thymic serum factors in man using the rosette technique. Transplant Rev (1973) 1.87
Transfer of symptomatic peanut allergy to the recipient of a combined liver-and-kidney transplant. N Engl J Med (1997) 1.83
Deficit of suppressor T cells in active multiple sclerosis. Lancet (1980) 1.83
Association of anti-beta 2 glycoprotein I antibodies with lupus-type circulating anticoagulant and thrombosis in systemic lupus erythematosus. Am J Med (1992) 1.82
The use of monoclonal anti-T cell antibodies to study T cell imbalances in human diseases. Clin Exp Immunol (1981) 1.82
Peanut agglutinin. I. A new tool for studying T lymphocyte subpopulations. J Immunol (1978) 1.80
A monoclonal anti-DNA antibody also binds to cell-surface protein(s). Proc Natl Acad Sci U S A (1984) 1.75
A gene for hereditary paroxysmal cerebellar ataxia maps to chromosome 19p. Ann Neurol (1995) 1.74
Anti-titin antibodies in myasthenia gravis: tight association with thymoma and heterogeneity of nonthymoma patients. Arch Neurol (2001) 1.73
Prevention of diabetes in NOD mice treated with antibody to murine IFN gamma. J Autoimmun (1991) 1.71
Systemic lupus erythematosus. Morphologic correlations with immunologic and clinical data at the time of biopsy. Am J Med (1978) 1.67
Poly(ADP-ribose) polymerase alleles in French Caucasians are associated neither with lupus nor with primary antiphospholipid syndrome. GRAID Research Group. Group for Research on Auto-Immune Disorders. Arthritis Rheum (1999) 1.67
Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups. Hum Mol Genet (1997) 1.65
Thymus dependency of rosette-forming cells: evidence for a circulating thymic hormone. Transplant Proc (1972) 1.63
Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus. J Clin Invest (1992) 1.63
Antigen recognition by T lymphocytes. II. Similar effects of azathioprine, antilymphocyte serum, and anti-theta serum on rosette-forming lymphocytes in normal and neonatally thymectomized mice. Cell Immunol (1972) 1.62
Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin. Diabetes (1990) 1.57
The peptide-binding motif for the human transporter associated with antigen processing. J Exp Med (1995) 1.56
Circulating plasma levels of nucleosomes in patients with systemic lupus erythematosus: correlation with serum antinucleosome antibody titers and absence of clear association with disease activity. Arthritis Rheum (1997) 1.55
Mature mainstream TCR alpha beta+CD4+ thymocytes expressing L-selectin mediate "active tolerance" in the nonobese diabetic mouse. J Immunol (1998) 1.55
The rheumatoid rosette. A diagnostic test unifying seropositive and seronegative rheumatoid arthritis. Am J Med (1970) 1.55
In vivo cell activation following OKT3 administration. Systemic cytokine release and modulation by corticosteroids. Transplantation (1990) 1.53
Early affect of adult thymectomy. Nat New Biol (1971) 1.53
Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases: antinucleosome antibodies of the IgG3 subclass are markers of renal pathogenicity in systemic lupus erythematosus. Arthritis Rheum (2000) 1.52
Binding of autologous erythrocytes to immature T-cells. Proc Natl Acad Sci U S A (1975) 1.43
Evaluation of T cell subsets in myasthenia gravis using anti-T cell monoclonal antibodies. Clin Exp Immunol (1981) 1.42
Thymic hormone-containing cells. Characterization and localization of serum thymic factor in young mouse thymus studied by monoclonal antibodies. J Exp Med (1982) 1.42
Characterization of facteur thymique sérique (FTS) in the thymus. I. Fixation of anti-FTS antibodies on thymic reticulo-epithelial cells. Clin Exp Immunol (1980) 1.40
Immunotherapy in pre-type 1 diabetes mellitus. Diabetologia (1990) 1.39
Cyclosporin and autoimmune disease. Lancet (1991) 1.39
Contribution of zinc and other metals to the biological activity of the serum thymic factor. Proc Natl Acad Sci U S A (1982) 1.37
Human in vivo antigenic modulation induced by the anti-T cell OKT3 monoclonal antibody. Eur J Immunol (1982) 1.37
Antigen recognition by T lymphocytes. Thymus and marrow dependence of spontaneous rosette forming cells in the mouse. Cell Immunol (1972) 1.37
Sex steroids, glucocorticoids, stress and autoimmunity. J Steroid Biochem Mol Biol (1991) 1.34
Structural study of circulating thymic factor: a peptide isolated from pig serum. II. Amino acid sequence. J Biol Chem (1977) 1.34
Systemic reaction to the anti-T-cell monoclonal antibody OKT3 in relation to serum levels of tumor necrosis factor and interferon-gamma [corrected]. N Engl J Med (1989) 1.34
Thymic factors. Prog Allergy (1976) 1.33
Correlation between mixed lymphocyte culture performed before renal transplantation and kidney function. Clin Exp Immunol (1970) 1.32
Binding of a monoclonal anti-DNA autoantibody to identical protein(s) present at the surface of several human cell types involved in lupus pathogenesis. J Clin Invest (1985) 1.31
Evidence for a serum-factor secreted by the human thymus. Lancet (1972) 1.30
In vitro detection of immunosuppressive activity of anti-lymphocyte sera. Nature (1968) 1.30
Thymic abnormalities in fetuses aborted from human immunodeficiency virus type 1 seropositive women. Pediatrics (1992) 1.28
Detection of humoral and cell-mediated immunity to kidney basement membranes in human renal diseases. Am J Med (1972) 1.28
Structural study of circulating thymic factor: a peptide isolated from pig serum. I. Isolation and purification. J Biol Chem (1977) 1.28
Studies on thymus products. 3. Epithelial origin of the serum thymic factor. Immunology (1974) 1.27
Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells. Proc Natl Acad Sci U S A (1988) 1.26
CTLA-4 gene polymorphism is associated with predisposition to coeliac disease. Gut (1998) 1.25
Serum thymulin in human zinc deficiency. J Clin Invest (1988) 1.23
Intrastrain recurrent idiotypes among anti-DNA antibodies of (NZB x NZW)F1 hybrid mice. Eur J Immunol (1982) 1.22
Further developments of the rosette inhibition test for the testing of antihuman lymphocyte serum. Transplantation (1971) 1.21
Detection of hepatitis B antigen in circulating immune complexes in acute and chronic hepatitis. Scand J Immunol (1977) 1.20
Activities of immunosuppressive agents in vitro. I. Rosette inhibition by azathioprine. Rev Eur Etud Clin Biol (1971) 1.20
Adoptive T cell transfer of autoimmune nonobese diabetic mouse diabetes does not require recruitment of host B lymphocytes. J Immunol (1988) 1.19
Influence of oral contraceptive therapy on the activity of systemic lupus erythematosus. Arthritis Rheum (1982) 1.19
Unusual phenotypes of human inducer T cells as measured by OKT4 and related monoclonal antibodies. J Immunol (1981) 1.18
Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice. Nature (1991) 1.18
Marked reduction of DNA antibody production and glomerulopathy in thymulin (FTS-Zn) or cyclosporin A treated (NZB X NZW) F1 mice. Clin Exp Immunol (1983) 1.17
The meiosis-specific Xmr gene product is homologous to the lymphocyte Xlr protein and is a component of the XY body. EMBO J (1994) 1.17
Antigen recognition by T lymphocytes. 3. Evidence for two populations of thymus-dependent rosette-forming cells in spleen and lymph nodes. Cell Immunol (1973) 1.16
A monoclonal anti-double-stranded DNA autoantibody binds to a 94-kDa cell-surface protein on various cell types via nucleosomes or a DNA-histone complex. Proc Natl Acad Sci U S A (1989) 1.16
Nucleosome-restricted antibodies are detected before anti-dsDNA and/or antihistone antibodies in serum of MRL-Mp lpr/lpr and +/+ mice, and are present in kidney eluates of lupus mice with proteinuria. Arthritis Rheum (1994) 1.15
Selective IgA deficiency and autoimmunity. Int Arch Allergy Immunol (1992) 1.15
Soluble tumor necrosis factor receptors in chronic hepatitis C: a correlation with histological fibrosis and activity. J Hepatol (1999) 1.15
The effects of steroids on T cells. Transplant Proc (1975) 1.15
Studies on thymus products. I. Modification of rosette-forming cells by thymic extracts. Determination of the target RFC sub-population. Immunology (1973) 1.13
Metabolic and immunological effects of cyclosporin in recently diagnosed type 1 diabetes mellitus. Lancet (1985) 1.13
Peripherin: an islet antigen that is cross-reactive with nonobese diabetic mouse class II gene products. Proc Natl Acad Sci U S A (1992) 1.13
Neonatal myasthenia gravis: a new clinical and immunologic appraisal on 30 cases. Neurology (1988) 1.12
Activities of immunosuppressive agents in vitro. II. Different timing of azathioprine and methotrexate in inhibition and stimulation of mixed lymphocyte reaction. Clin Exp Immunol (1972) 1.12
Fate of circulating immune complexes in infective endocarditis. Am J Med (1979) 1.12
Acceleration of the onset of diabetes in NOD mice by thymectomy at weaning. Eur J Immunol (1989) 1.11
Influence of castration, alone or combined with thymectomy, on the development of diabetes in the nonobese diabetic mouse. Endocrinology (1991) 1.11
IL-7 reverses NK1+ T cell-defective IL-4 production in the non-obese diabetic mouse. Int Immunol (1996) 1.11
Monoclonal antibody against the serum thymic factor (FTS). Immunol Lett (1982) 1.10