| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Monocyclic beta-lactam antibiotics produced by bacteria.
|
Nature
|
1981
|
3.61
|
|
2
|
Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents.
|
J Med Chem
|
1991
|
3.11
|
|
3
|
Dihydropyrimidine calcium channel blockers: 2-heterosubstituted 4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.
|
J Med Chem
|
1990
|
2.70
|
|
4
|
Dihydropyrimidine calcium channel blockers. 2. 3-substituted-4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.
|
J Med Chem
|
1990
|
1.60
|
|
5
|
The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide.
|
J Med Chem
|
1994
|
0.94
|
|
6
|
Benzazepinone calcium channel blockers. 4. Structure-activity overview and intracellular binding site.
|
J Med Chem
|
1992
|
0.84
|
|
7
|
Pharmacological characterization of potent, long-acting thromboxane receptor antagonists, SQ 33,261 and SQ 33,552.
|
J Pharmacol Exp Ther
|
1992
|
0.79
|
|
8
|
1-Benzazepin-2-one calcium channel blockers--VI. Receptor-binding model and possible relationship to desmethoxyverapamil.
|
Bioorg Med Chem
|
1993
|
0.78
|
|
9
|
Benzazepinone calcium channel blockers. 5. Effects on antihypertensive activity associated with N1 and aromatic substituents.
|
J Med Chem
|
1992
|
0.78
|
|
10
|
Hydroxyamino acid specificity of smooth muscle myosin light chain kinase.
|
Arch Biochem Biophys
|
1988
|
0.77
|
|
11
|
Benzazepinone calcium channel blockers. 3. Synthesis and structure-activity studies of 3-alkylbenzazepinones.
|
J Med Chem
|
1992
|
0.77
|
|
12
|
A rapid and versatile method for screening endothelin converting enzyme activity.
|
J Pharmacol Toxicol Methods
|
1994
|
0.76
|
|
13
|
SQ 26,180, a novel monobactam. II Isolation, structure determination and synthesis.
|
J Antibiot (Tokyo)
|
1982
|
0.76
|
|
14
|
Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists.
|
J Med Chem
|
1995
|
0.76
|
|
15
|
Minimum requirements for inhibition of smooth-muscle myosin light-chain kinase by synthetic peptides.
|
Biochem J
|
1989
|
0.75
|
|
16
|
SQ 27,786 and SQ 28,853: two angiotensin converting enzyme inhibitors with potent diuretic activity.
|
J Cardiovasc Pharmacol
|
1987
|
0.75
|
|
17
|
11,15-Epiprostaglandin E 2 and its enantiomer. Biological activity and synthesis.
|
J Org Chem
|
1972
|
0.75
|
|
18
|
Structure-activity studies of endothelin leading to novel peptide ETA antagonists.
|
Bioorg Med Chem
|
1993
|
0.75
|
|
19
|
Extraction of light filth from tea: collaborative study.
|
J Assoc Off Anal Chem
|
1981
|
0.75
|
|
20
|
Type and hold system for better blood utilization.
|
Transfusion
|
1981
|
0.75
|
|
21
|
Monobactams: isolation and structure determination.
|
J Antimicrob Chemother
|
1981
|
0.75
|
|
22
|
Site-specific biotinylation. A novel approach and its application to endothelin-1 analogs and PTH-analog.
|
Int J Pept Protein Res
|
1992
|
0.75
|
|
23
|
The preparation of leukocyte-poor red cells from AS-1 red cells by the spin-cool-filter method.
|
Transfusion
|
1987
|
0.75
|
|
24
|
Quantitation of ABO mixed-cell populations by a peroxidase-anti-peroxidase immunoenzyme method.
|
Transfusion
|
1982
|
0.75
|