M L Webb

Author PubWeight™ 25.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Endothelin-1 and angiotensin-II stimulate delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for common signaling mechanisms. Mol Endocrinol 1994 1.02
2 The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide. J Med Chem 1994 0.94
3 Control of peptide disulfide regioisomer formation by mixed cysteine-penicillamine bridges. Application to endothelin-1. Int J Pept Protein Res 1993 0.90
4 Mutation of peptide binding site in transmembrane region of a G protein-coupled receptor accounts for endothelin receptor subtype selectivity. J Biol Chem 1994 0.89
5 Effect of in-house transport on murine plasma corticosterone concentration and blood lymphocyte populations. Am J Vet Res 1990 0.87
6 Hypoxia stimulates human preproendothelin-1 promoter activity in transgenic mice. Am J Physiol 1997 0.87
7 Pharmacological profile of BMS 180,291: a potent, long-acting, orally active thromboxane A2/prostaglandin endoperoxide receptor antagonist. J Pharmacol Exp Ther 1993 0.86
8 Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N- (3,4-dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)[1, 1'-biphenyl]-2-sulfonamide (BMS-187308). J Med Chem 1998 0.85
9 Aspartate mutation distinguishes ETA but not ETB receptor subtype-selective ligand binding while abolishing phospholipase C activation in both receptors. FEBS Lett 1995 0.84
10 Vascular A10 cell membranes contain an endothelin metabolizing neutral endopeptidase. Biochem Biophys Res Commun 1991 0.84
11 Early signal transduction by the receptor to the chemokine monocyte chemotactic protein-1 in a murine T cell hybrid. J Immunol 1996 0.83
12 Exogenous effects and endogenous production of endothelin in cardiac myocytes: potential significance in heart failure. Am J Physiol 1996 0.83
13 Thermal activation of the purified rat hepatic glucocorticoid receptor. Evidence for a two-step mechanism. J Biol Chem 1985 0.82
14 Purification, characterization, and activation of the glucocorticoid-receptor complex from rat kidney cortex. Biochemistry 1985 0.82
15 DuP 753, the selective angiotensin II receptor blocker, is a competitive antagonist to human platelet thromboxane A2/prostaglandin H2 (TP) receptors. Prostaglandins 1992 0.81
16 Effects of bovine pancreatic ribonuclease A, S protein, and S peptide on activation of purified rat hepatic glucocorticoid-receptor complexes. Biochemistry 1986 0.81
17 Characterization of a monoclonal antibody that probes the functional domains of the glucocorticoid receptor. Biochem J 1987 0.80
18 Cloning and expression of a human endothelin receptor: subtype A. Am J Med Sci 1992 0.80
19 Interaction of a positive regulatory factor(s) with a 106-base pair upstream region controls transcription of metallothionein-I gene in the liver. J Biol Chem 1989 0.80
20 Role of endothelin receptor subtype B (ET-B) in myocardial ischemia. Life Sci 1994 0.79
21 Accurate transcription of mouse metallothionein-I gene in a fractionated nuclear extract from a rat hepatoma. J Biol Chem 1987 0.79
22 Serum testosterone concentration during two hours of moderate intensity treadmill running in trained men and women. Endocr Res 1984 0.78
23 Evidence for an association of a ribonucleic acid with the purified, unactivated glucocorticoid receptor. Biochem Biophys Res Commun 1986 0.78
24 Biphenylsulfonamide endothelin receptor antagonists. 2. Discovery of 4'-oxazolyl biphenylsulfonamides as a new class of potent, highly selective ET(A) antagonists. J Med Chem 2000 0.78
25 Changes in serum corticosterone concentration of laying hens as a response to increased population density. Poult Sci 1984 0.78
26 Peptidases and smooth muscle cell angiotensin II receptor pharmacology. Peptides 1993 0.77
27 Characterization of binding of a specific antagonist, [3H]-SQ 29,548, to soluble thromboxane A2/prostaglandin H2 (TP) receptors in human platelet membranes. Life Sci 1992 0.77
28 Effect of adaptation to handling on the circulating corticosterone concentration of laying hens. Br Poult Sci 1984 0.77
29 Decreased glucocorticoid binding and receptor activation in brain of genetically diabetic (MDB/MDB) mice. J Steroid Biochem 1986 0.77
30 Maturation of the diurnal rhythm of corticosterone in female domestic fowl. Poult Sci 1985 0.76
31 Small molecule antagonists of the bradykinin B1 receptor. Immunopharmacology 1999 0.76
32 A role for endothelin ETA receptors in regulation of renal function in spontaneously hypertensive rats. Eur J Pharmacol 1995 0.76
33 Endothelins stimulate mitogen-activated protein kinase cascade through either ETA or ETB. Am J Physiol 1994 0.75
34 Relationship between progesterone and egg production in pheasants. Poult Sci 1982 0.75
35 Some of the objectives, attainments, aspirations and possible future developments of health care in the North. Can J Ophthalmol 1973 0.75
36 Interphenylene 7-oxabicyclo[2.2.1]heptane thromboxane A2 antagonists. Semicarbazone omega-chains. J Med Chem 1991 0.75
37 Comparison of a novel ETA receptor antagonist and phosphoramidon in renal ischemia. Pharmacology 1995 0.75
38 Angiotensin-converting enzyme inhibition and angiotensin II subtype-1 receptor blockade during the progression of left ventricular dysfunction: differential effects on myocyte contractile processes. J Pharmacol Exp Ther 1997 0.75
39 Production of monoclonal antibodies against RNA polymerase I from nonimmunized autoimmune MRL/lpr mice and their use in rDNA transcription analysis. J Biol Chem 1987 0.75
40 The effects of endothelin-A receptor blockade during the progression of pacing-induced congestive heart failure. J Am Coll Cardiol 1998 0.75
41 Regulation of the rat aortic smooth muscle cell thromboxane A2 receptor. Trans Assoc Am Physicians 1991 0.75
42 Urinary incontinence in younger women. Nurse Pract Forum 1994 0.75
43 Binding of 125I-endothelin-1 and 125I-endothelin-3 in rabbit saphenous vein: evidence for an atypical ET binding component. J Cardiovasc Pharmacol 1993 0.75