Published in CMAJ on February 15, 1994
Variability in prescription drug utilization: issues for research. CMAJ (1996) 1.24
The diagnosis and management of insomnia in clinical practice: a practical evidence-based approach. CMAJ (2000) 1.13
The lesser evil? Initiating a benzodiazepine prescription in general practice: a qualitative study on GPs' perspectives. Scand J Prim Health Care (2007) 1.10
Pharmaceutical policies in Canadian family medicine training. Survey of residency programs. Can Fam Physician (1997) 0.81
Cutting costs by targeting prescribing practices. CMAJ (1994) 0.75
Cutting costs by targeting prescribing practices. CMAJ (1994) 0.75
Practitioners and health policy. Case of the Ontario Drug Benefit Plan. Can Fam Physician (1995) 0.75
Pharmaceutical advertisements in leading medical journals: experts' assessments. Ann Intern Med (1992) 10.06
Should there be a moratorium on the use of cholesterol lowering drugs? BMJ (1992) 9.85
Opinion leaders vs audit and feedback to implement practice guidelines. Delivery after previous cesarean section. JAMA (1991) 9.71
Measured enthusiasm: does the method of reporting trial results alter perceptions of therapeutic effectiveness? Ann Intern Med (1992) 7.65
Psychotropic drug use and the risk of hip fracture. N Engl J Med (1987) 7.53
Lowering cholesterol concentrations and mortality: a quantitative review of primary prevention trials. BMJ (1990) 6.70
The publication of sponsored symposiums in medical journals. N Engl J Med (1992) 5.67
Health policy on blood cholesterol. Time to change directions. Circulation (1992) 4.71
Clinical review of histamine2 receptor antagonists. Arch Intern Med (1990) 3.68
Trends and determinants of prescription drug expenditures in the elderly: data from the British Columbia Pharmacare Program. Inquiry (1993) 1.84
Treating hypercholesterolemia. How should practicing physicians interpret the published data for patients? N Engl J Med (1989) 1.84
Economic and policy analysis of university-based drug "detailing". Med Care (1986) 1.67
Central nervous system reactions to histamine-2 receptor blockers. Ann Intern Med (1991) 1.49
Indicative drug budgets for general practitioners: a prescription for change. BMJ (1989) 1.27
Grampian Health Board's joint drug formulary. BMJ (1990) 1.26
The risks and benefits of an Rx-to-OTC switch. The case of over-the-counter H2-blockers. Med Care (1990) 1.23
A population-wide profile of prescription drug use in Saskatchewan, 1989. CMAJ (1992) 1.08
Promoting rational therapeutics: the Swedish guidelines and a UK response. Br J Gen Pract (1990) 1.05
Lowering cholesterol: effects on trauma death, cancer death and total mortality. Aust N Z J Med (1992) 0.93
A congressional perspective on inappropriate drug therapy and drug utilization review. Clin Pharmacol Ther (1991) 0.86
The Nelson general practice prescribing project. Part I: A pilot audit of the regional prescribing profile. N Z Med J (1990) 0.84
Characteristics of pharmaceutical opinions written in a Quebec community pharmacy. Ann Pharmacother (1992) 0.84
PACT and prescribing. Practitioner (1991) 0.83
Do practice guidelines guide practice? The effect of a consensus statement on the practice of physicians. N Engl J Med (1989) 16.77
Opinion leaders vs audit and feedback to implement practice guidelines. Delivery after previous cesarean section. JAMA (1991) 9.71
Effects of socioeconomic status on access to invasive cardiac procedures and on mortality after acute myocardial infarction. N Engl J Med (1999) 7.68
Use of medical resources and quality of life after acute myocardial infarction in Canada and the United States. N Engl J Med (1994) 6.78
Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell (1997) 5.99
Users' guides to the medical literature: XXII: how to use articles about clinical decision rules. Evidence-Based Medicine Working Group. JAMA (2000) 5.94
Users' guides to the medical literature. XII. How to use articles about health-related quality of life. Evidence-Based Medicine Working Group. JAMA (1997) 5.07
Incorporating variations in the quality of individual randomized trials into meta-analysis. J Clin Epidemiol (1992) 4.86
Use of cardiac procedures and outcomes in elderly patients with myocardial infarction in the United States and Canada. N Engl J Med (1997) 4.84
How should health status measures be assessed? Cautionary notes on procrustean frameworks. J Clin Epidemiol (1992) 4.54
Controlling health expenditures--the Canadian reality. N Engl J Med (1989) 4.36
Meta-analysis and the meta-epidemiology of clinical research. BMJ (1997) 4.07
Do we know what inappropriate laboratory utilization is? A systematic review of laboratory clinical audits. JAMA (1998) 3.96
Assessing the clinical effectiveness of preventive maneuvers: analytic principles and systematic methods in reviewing evidence and developing clinical practice recommendations. A report by the Canadian Task Force on the Periodic Health Examination. J Clin Epidemiol (1990) 3.88
Systematic implementation of an advance directive program in nursing homes: a randomized controlled trial. JAMA (2000) 3.87
Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins. J Biol Chem (1994) 3.73
Cost effectiveness of thrombolytic therapy with tissue plasminogen activator as compared with streptokinase for acute myocardial infarction. N Engl J Med (1995) 3.69
Recent findings on preventable hospitalizations. Health Aff (Millwood) (1996) 3.66
Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann Intern Med (1993) 3.53
Socio-economic status and the utilisation of physicians' services: results from the Canadian National Population Health Survey. Soc Sci Med (2000) 3.41
Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium. J Immunol (1999) 3.39
Communicating the benefits of chronic preventive therapy: does the format of efficacy data determine patients' acceptance of treatment? Med Decis Making (1995) 3.21
Determinants of the increasing cesarean birth rate. Ontario data 1979 to 1982. N Engl J Med (1984) 3.16
What is the quality of drug therapy clinical practice guidelines in Canada? CMAJ (2001) 3.15
Are antibiotics effective treatment for acute bronchitis? A meta-analysis. J Fam Pract (1998) 3.12
Regionalization of cardiac surgery in the United States and Canada. Geographic access, choice, and outcomes. JAMA (1995) 3.12
Impact of increasing carbohydrate intolerance on maternal-fetal outcomes in 3637 women without gestational diabetes. The Toronto Tri-Hospital Gestational Diabetes Project. Am J Obstet Gynecol (1995) 3.05
Multicenter validation of a risk index for mortality, intensive care unit stay, and overall hospital length of stay after cardiac surgery. Steering Committee of the Provincial Adult Cardiac Care Network of Ontario. Circulation (1995) 3.02
Emergence of self-destructive phenomena in children and adolescents during fluoxetine treatment. J Am Acad Child Adolesc Psychiatry (1991) 3.02
Trends in use of medical services by the elderly in British Columbia. CMAJ (1989) 2.88
Variation in breast cancer surgery in Ontario. CMAJ (1994) 2.70
Ready-made, recalibrated, or Remodeled? Issues in the use of risk indexes for assessing mortality after coronary artery bypass graft surgery. Circulation (1999) 2.67
Comparison of an aggressive (U.S.) and a less aggressive (Canadian) policy for cholesterol screening and treatment. Ann Intern Med (1991) 2.61
Multicentre trial to introduce the Ottawa ankle rules for use of radiography in acute ankle injuries. Multicentre Ankle Rule Study Group. BMJ (1995) 2.50
The fall and rise of carotid endarterectomy in the United States and Canada. N Engl J Med (1998) 2.48
The death of cost-minimization analysis? Health Econ (2001) 2.45
Appropriateness in health care delivery: definitions, measurement and policy implications. CMAJ (1996) 2.27
Autism as a disorder of neural information processing: directions for research and targets for therapy. Mol Psychiatry (2004) 2.19
Case-based reasoning and imaging procedure selection. Invest Radiol (1994) 2.19
Relation between severity of Alzheimer's disease and costs of caring. CMAJ (1998) 2.12
Epithelial antibiotic induced in states of disease. Proc Natl Acad Sci U S A (1997) 2.11
Characteristics and mortality outcomes of thrombolysis trial participants and nonparticipants: a population-based comparison. J Am Coll Cardiol (1996) 2.09
Aspartame, behavior, and cognitive function in children with attention deficit disorder. Pediatrics (1994) 2.08
Temporal changes in the outcomes of acute myocardial infarction in Ontario, 1992-1996. CMAJ (1999) 2.04
Expression of human tissue factor under the control of the mouse tissue factor promoter mediates normal hemostasis in knock-in mice. J Thromb Haemost (2007) 2.00
What is appropriate care? N Engl J Med (1998) 1.97
Diagnostic accuracy and short-term surgical outcomes in cases of suspected acute appendicitis. CMAJ (1995) 1.91
Coronary artery bypass graft surgery in Ontario and New York State: which rate is right? Steering Committee of the Cardiac Care Network of Ontario. Ann Intern Med (1997) 1.89
False-positive coding for acute myocardial infarction on hospital discharge records: chart audit results from a tertiary centre. Can J Cardiol (1990) 1.87
Fairness in the coronary angiography queue. CMAJ (1999) 1.83
A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus. Am J Hum Genet (2001) 1.80
Coronary artery bypass grafting in Canada: What is its rate of use? Which rate is right? CMAJ (1992) 1.71
Patterns of practice among older physicians in Ontario. CMAJ (1998) 1.66
Long-term MI outcomes at hospitals with or without on-site revascularization. JAMA (2001) 1.66
A survey of provider experiences and perceptions of preferential access to cardiovascular care in Ontario, Canada. Ann Intern Med (1998) 1.66
Coronary artery bypass mortality rates in Ontario. A Canadian approach to quality assurance in cardiac surgery. Steering Committee of the Provincial Adult Cardiac Care Network of Ontario. Circulation (1996) 1.61
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Hospitalization for ambulatory care-sensitive conditions: a method for comparative access and quality studies using routinely collected statistics. Can J Public Health (2001) 1.58
Maternal and newborn outcomes among women with schizophrenia: a retrospective population-based cohort study. BJOG (2014) 1.58
Localized antimicrobial peptide expression in human gingiva. J Periodontal Res (2001) 1.58
Appropriateness of primary total hip and knee replacements in regions of Ontario with high and low utilization rates. CMAJ (1996) 1.56
Confidence intervals for cost-effectiveness ratios: an application of Fieller's theorem. Health Econ (1997) 1.55
Incidence of diabetes among postmenopausal breast cancer survivors. Diabetologia (2012) 1.55
Risperidone treatment of children and adolescents with pervasive developmental disorders: a prospective open-label study. J Am Acad Child Adolesc Psychiatry (1997) 1.54
Use of vitamin B12 injections among elderly patients by primary care practitioners in Ontario. CMAJ (1999) 1.54
Flat on your back or back to your flat? Sources of increased hospital services utilization among the elderly in British Columbia. Soc Sci Med (1990) 1.53
The burden of waiting for hip and knee replacements in Ontario. Ontario Hip and Knee Replacement Project Team. J Eval Clin Pract (1997) 1.53
Potential cost effectiveness of intravenous tissue plasminogen activator versus streptokinase for acute myocardial infarction. Can J Cardiol (1992) 1.52
Tryptophan depletion during continuous CSF sampling in healthy human subjects. Neuropsychopharmacology (1998) 1.51
The valuation of productivity costs due to premature mortality: a comparison of the human-capital and friction-cost methods for schizophrenia. Can J Psychiatry (1999) 1.50
Dealing with missing data in observational health care outcome analyses. J Clin Epidemiol (2000) 1.49
Cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid in autism. Biol Psychiatry (1993) 1.46
A haplotype at the DBH locus, associated with low plasma dopamine beta-hydroxylase activity, also associates with cocaine-induced paranoia. Mol Psychiatry (2000) 1.44
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
The relationship between cardiac functional capacity and patients' symptom-specific utilities for angina: some findings and methodologic lessons. Med Decis Making (1996) 1.41
Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology (2003) 1.41
Assessing the quality of care in family physicians' practices. Can Fam Physician (1985) 1.40
Antibiotics for acute bronchitis. Cochrane Database Syst Rev (2000) 1.40
Trends in clinical and economic outcomes of coronary angioplasty from 1992 to 1995: a population-based analysis. Am Heart J (1999) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Assessing the outcomes of coronary artery bypass graft surgery: how many risk factors are enough? Steering Committee of the Cardiac Care Network of Ontario. J Am Coll Cardiol (1997) 1.39
In the queue for total joint replacement: patients' perspectives on waiting times. Ontario Hip and Knee Replacement Project Team. J Eval Clin Pract (1998) 1.37
Comparison of the appropriateness of coronary angiography and coronary artery bypass graft surgery between Canada and New York State. JAMA (1994) 1.35
Biology or bias: practice patterns and long-term outcomes for men and women with acute myocardial infarction. J Am Coll Cardiol (2002) 1.35
Health services research: reporting on studies using secondary data sources. CMAJ (1996) 1.35
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Fifteen-year trends in risk severity and operative mortality in elderly patients undergoing coronary artery bypass graft surgery. Circulation (1998) 1.32
Determination of serotonin in whole blood, platelet-rich plasma, platelet-poor plasma and plasma ultrafiltrate. Life Sci (1987) 1.31
A Canadian physician survey of dyspepsia management. Can J Gastroenterol (1998) 1.30
Role of the serotonin transporter gene in the behavioral expression of autism. Mol Psychiatry (2001) 1.30
No impact from active dissemination of the Ottawa Ankle Rules: further evidence of the need for local implementation of practice guidelines. CMAJ (1999) 1.30
A comparison of a Bayesian vs. a frequentist method for profiling hospital performance. J Eval Clin Pract (2001) 1.29
Measuring the effectiveness of heart transplant programmes: quality of life data and their relationship to survival analysis. J Chronic Dis (1987) 1.27
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27