Published in Am J Pathol on August 01, 1993
The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice. Am J Pathol (2002) 2.22
Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing. J Cell Biol (1995) 1.85
Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration. J R Soc Interface (2007) 1.68
Roles for the type III TGF-beta receptor in human cancer. Cell Signal (2010) 1.50
TGFβ1 overexpression by keratinocytes alters skin dendritic cell homeostasis and enhances contact hypersensitivity. J Invest Dermatol (2012) 1.47
Differential expression of fibromodulin, a transforming growth factor-beta modulator, in fetal skin development and scarless repair. Am J Pathol (2000) 1.38
CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth. Cell Cycle (2012) 1.37
Vascular remodeling in primary pulmonary hypertension. Potential role for transforming growth factor-beta. Am J Pathol (1994) 1.32
Sustained release of TGFbeta3 from PLGA microspheres and its effect on early osteogenic differentiation of human mesenchymal stem cells. Tissue Eng (2006) 1.19
Expression of transforming growth factor-beta 2 in malignant melanoma correlates with the depth of tumor invasion. Implications for tumor progression. Am J Pathol (1994) 1.19
Proteoglycan distribution in lesions of atherosclerosis depends on lesion severity, structural characteristics, and the proximity of platelet-derived growth factor and transforming growth factor-beta. Am J Pathol (1998) 1.13
Ontogenetic transition in fetal wound transforming growth factor-beta regulation correlates with collagen organization. Am J Pathol (2003) 1.13
Inhibition of osteogenic differentiation of human mesenchymal stem cells. Wound Repair Regen (2007) 1.11
Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring. Am J Pathol (2003) 1.11
Calreticulin enhances porcine wound repair by diverse biological effects. Am J Pathol (2008) 1.10
Increased expression of transforming growth factor beta s after acute oedematous pancreatitis in rats suggests a role in pancreatic repair. Gut (1997) 1.07
Expression of growth factors and receptors during specific phases in regenerating urothelium after acute injury in vivo. Am J Pathol (1994) 1.02
Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer. Clin Transl Med (2014) 0.99
Enhanced expression of TGF-betas and their receptors in human acute pancreatitis. Ann Surg (1998) 0.97
Type I (RI) and type II (RII) receptors for transforming growth factor-beta isoforms are expressed subsequent to transforming growth factor-beta ligands during excisional wound repair. Am J Pathol (1997) 0.97
A review of fetal scarless healing. ISRN Dermatol (2012) 0.96
Tissue repair processes in healing chronic pressure ulcers treated with recombinant platelet-derived growth factor BB. Am J Pathol (1994) 0.93
Expression of transforming growth factor-beta isoforms and their receptors in chronic tendinosis. J Anat (2001) 0.92
Particle-mediated gene transfer with transforming growth factor-beta1 cDNAs enhances wound repair in rat skin. J Clin Invest (1996) 0.91
Tumor necrosis factor-alpha inhibits collagen alpha1(I) gene expression and wound healing in a murine model of cachexia. Am J Pathol (1996) 0.91
Effects of octreotide acetate and amniotic membrane on wound healing in experimental glaucoma surgery. Doc Ophthalmol (2003) 0.90
Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes. J Invest Dermatol (2007) 0.90
Interleukin (IL)-6 modulates transforming growth factor-beta expression in skin and dermal fibroblasts from IL-6-deficient mice. Br J Dermatol (2009) 0.90
Effect of connective tissue growth factor (CCN2/CTGF) on proliferation and differentiation of mouse periodontal ligament-derived cells. Cell Commun Signal (2005) 0.87
Expression, purification and characterization of BG(E)RII: a novel pan-TGFbeta inhibitor. Protein Eng Des Sel (2008) 0.87
Transforming growth factor Beta 3 is required for excisional wound repair in vivo. PLoS One (2012) 0.86
Axolotl as a Model to Study Scarless Wound Healing in Vertebrates: Role of the Transforming Growth Factor Beta Signaling Pathway. Adv Wound Care (New Rochelle) (2013) 0.85
Fibromodulin-deficiency alters temporospatial expression patterns of transforming growth factor-β ligands and receptors during adult mouse skin wound healing. PLoS One (2014) 0.84
Differential expression of TGF-beta isoforms during differentiation of HaCaT human keratinocyte cells: implication for the separate role in epidermal differentiation. J Korean Med Sci (2004) 0.83
Latent TGFbeta binding protein-1 and fibrillin-1 in human capsular opacification and in cultured lens epithelial cells. Br J Ophthalmol (2001) 0.83
Dysregulation of autocrine TGF-beta isoform production and ligand responses in human tumour-derived and Ha-ras-transfected keratinocytes and fibroblasts. Br J Cancer (1996) 0.82
Tissue interactions between craniosynostotic dura mater and bone. J Craniofac Surg (2012) 0.81
Suramin inhibits wound healing following filtering procedures for glaucoma. Br J Ophthalmol (1998) 0.80
Effects of cold atmospheric plasma (CAP) on ß-defensins, inflammatory cytokines, and apoptosis-related molecules in keratinocytes in vitro and in vivo. PLoS One (2015) 0.80
Genotype-Specific Interaction of Latent TGFβ Binding Protein 4 with TGFβ. PLoS One (2016) 0.77
Identifying Novel Targets for Treatment of Liver Fibrosis: What Can We Learn from Injured Tissues which Heal Without a Scar? Curr Drug Targets (2015) 0.77
Palatogenesis and cutaneous repair: A two-headed coin. Dev Dyn (2014) 0.76
Digital imaging analysis to assess scar phenotype. Wound Repair Regen (2014) 0.75
Effects of ranibizumab on TGF-β1 and TGF-β2 production by human Tenon's fibroblasts: An in vitro study. Mol Vis (2015) 0.75
Differential Expression of TGF-β Isoforms in Human Kerationocytes by Narrow Band UVB. Ann Dermatol (2008) 0.75
Re-epithelialization resulted from prostate basal cells in canine prostatic urethra may represent the ideal healing method after two-micron laser resection of the prostate. Asian J Androl (2015) 0.75
Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem (1986) 10.00
Type beta transforming growth factor: a bifunctional regulator of cellular growth. Proc Natl Acad Sci U S A (1985) 5.93
Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta. J Exp Med (1987) 4.35
Accelerated healing of incisional wounds in rats induced by transforming growth factor-beta. Science (1987) 4.03
Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J Cell Biol (1991) 3.38
Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium. Cancer Res (1986) 2.83
Mesoderm induction in amphibians: the role of TGF-beta 2-like factors. Science (1988) 2.68
Overexpression of transforming growth factor alpha in psoriatic epidermis. Science (1989) 2.63
Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms. J Cell Biol (1989) 2.54
In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. Development (1990) 2.53
Cell adhesion protein receptors as targets for transforming growth factor-beta action. Cell (1987) 2.41
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Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family. EMBO J (1987) 2.23
Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-beta. Science (1990) 2.22
Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta. J Exp Med (1990) 2.19
Two forms of transforming growth factor-beta distinguished by multipotential haematopoietic progenitor cells. Nature (1987) 2.13
Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane. J Cell Biol (1990) 2.09
Localized production of TGF-beta mRNA in tumour promoter-stimulated mouse epidermis. Nature (1988) 1.99
Fibronectin-associated transforming growth factor. J Cell Physiol (1987) 1.89
Transforming growth factor-beta inhibits endothelial cell proliferation. Biochem Biophys Res Commun (1986) 1.86
Transforming growth factor beta reverses the glucocorticoid-induced wound-healing deficit in rats: possible regulation in macrophages by platelet-derived growth factor. Proc Natl Acad Sci U S A (1989) 1.73
Platelet-derived growth factor-BB and transforming growth factor beta 1 selectively modulate glycosaminoglycans, collagen, and myofibroblasts in excisional wounds. Am J Pathol (1991) 1.69
Transforming growth factor type beta specifically stimulates synthesis of proteoglycan in human adult arterial smooth muscle cells. Proc Natl Acad Sci U S A (1987) 1.64
Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. Dev Biol (1990) 1.59
Transforming growth factor-beta 1 up-regulates type IV collagenase expression in cultured human keratinocytes. J Biol Chem (1991) 1.59
Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia. J Exp Med (1991) 1.55
Growth factor-induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model. J Clin Invest (1991) 1.48
Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways. Proc Natl Acad Sci U S A (1991) 1.43
Co-localization of transforming growth factor beta 2 with alpha 1(I) procollagen mRNA in tissue sections of patients with systemic sclerosis. J Clin Invest (1990) 1.36
Role of PDGF-A expression in the control of vascular smooth muscle cell growth by transforming growth factor-beta. J Cell Biol (1990) 1.35
Transforming growth factor beta 1 modulates extracellular matrix organization and cell-cell junctional complex formation during in vitro angiogenesis. J Cell Physiol (1990) 1.31
Modulation of keratinocyte motility. Correlation with production of extracellular matrix molecules in response to growth promoting and antiproliferative factors. Am J Pathol (1988) 1.29
TGF-beta and retinoic acid: regulators of growth and modifiers of differentiation in human epidermal cells. Cell Regul (1990) 1.28
Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin. I. Excisional wound model. Lab Invest (1990) 1.25
Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 mRNA and protein in the murine lung. Am J Respir Cell Mol Biol (1991) 1.23
Type beta transforming growth factor (TGF beta) regulation of alkaline phosphatase expression and other phenotype-related mRNAs in osteoblastic rat osteosarcoma cells. J Cell Physiol (1987) 1.22
Comparison of the biological actions of TGF beta-1 and TGF beta-2: differential activity in endothelial cells. J Cell Physiol (1988) 1.22
Bi-functional action of transforming growth factor-beta on DNA synthesis in early passage human fetal fibroblasts. J Cell Physiol (1986) 1.21
Transforming growth factor-beta 1 localization in normal and psoriatic epidermal keratinocytes in situ. J Cell Physiol (1990) 1.17
Transcription and expression of transforming growth factor type beta in the skin of progressive systemic sclerosis: a mediator of fibrosis? J Invest Dermatol (1990) 1.17
Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: incisional wound model. J Invest Dermatol (1991) 1.15
Retinoic acid-induced alterations in the expression of growth factors in embryonic mouse palatal shelves. Teratology (1990) 1.13
Evaluation of transforming growth factor beta and type I procollagen gene expression in fibrotic skin diseases by in situ hybridization. J Invest Dermatol (1990) 1.09
Stimulatory effects of transforming growth factor-beta and epidermal growth factor on epidermal cell outgrowth from porcine skin explant cultures. J Invest Dermatol (1988) 1.08
Role of transforming growth factor beta in the maturation of human epidermal keratinocytes. J Invest Dermatol (1988) 1.02
Quantitative analysis of inflammatory cell influx, procollagen type I synthesis, and collagen cross-linking in incisional wounds: influence of PDGF-BB and TGF-beta 1 therapy. J Lab Clin Med (1991) 0.98
Current concepts in wound healing: growth factor and macrophage interaction. J Trauma (1990) 0.94
Fibronectin-mediated keratinocyte migration and initiation of fibronectin receptor function in vitro. J Invest Dermatol (1985) 0.91
Induction of extracellular matrix gene expression in normal human keratinocytes by transforming growth factor beta is altered by cellular differentiation. Exp Cell Res (1991) 0.91
Exogenous transforming growth factor-beta 2 enhances connective tissue formation and wound strength in guinea pig dermal wounds healing by secondary intent. Ann Surg (1990) 0.85
Reversal of Adriamycin-impaired wound healing by transforming growth factor-beta. Surg Gynecol Obstet (1989) 0.84
Recombinant transforming growth factor beta accelerates incisional wound healing. Curr Surg (1989) 0.84
Differential acceleration of healing of surgical incisions in the rabbit gastrointestinal tract by platelet-derived growth factor and transforming growth factor, type beta. Surgery (1990) 0.82
TGF-alpha and TGF-beta expression during sodium-N-butyrate-induced differentiation of human keratinocytes: evidence for subpopulation-specific up-regulation of TGF-beta mRNA in suprabasal cells. Exp Cell Res (1990) 0.80
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Growth inhibitor from BSC-1 cells closely related to platelet type beta transforming growth factor. Science (1984) 5.20
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. J Biol Chem (2000) 5.00
Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta. J Exp Med (1987) 4.35
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. J Cell Biol (1988) 4.34
Production and auto-induction of transforming growth factor-alpha in human keratinocytes. Nature (1987) 4.19
Serum contains a platelet-derived transforming growth factor. Proc Natl Acad Sci U S A (1982) 3.88
Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin. J Cell Biol (1990) 3.81
TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell (1990) 3.55
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Enhancement of wound healing by topical treatment with epidermal growth factor. N Engl J Med (1989) 3.39
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Transforming growth factor production by chemically transformed cells. Cancer Res (1981) 3.36
Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity. Proc Natl Acad Sci U S A (1986) 3.04
Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity. J Biol Chem (2001) 3.04
Specific binding to cultured cells of 125I-labeled type beta transforming growth factor from human platelets. Proc Natl Acad Sci U S A (1984) 3.01
Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology (1993) 2.86
Fibronectin: a review of its structure and biological activity. Mol Cell Biochem (1980) 2.85
Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium. Cancer Res (1986) 2.83
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Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts. J Clin Invest (1987) 2.74
Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis. J Cell Biol (1997) 2.72
Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription. J Biol Chem (1999) 2.56
In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. Development (1990) 2.53
Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer. Cancer Res (1992) 2.29
Delayed wound healing in CXCR2 knockout mice. J Invest Dermatol (2000) 2.20
Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta. Mol Cell Biol (1988) 2.20
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Transforming growth factors and the regulation of cell proliferation. Eur J Biochem (1990) 2.15
Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1. Genes Dev (1993) 2.13
Regulation of intestinal epithelial cell growth by transforming growth factor type beta. Proc Natl Acad Sci U S A (1989) 2.09
Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane. J Cell Biol (1990) 2.09
Mammary tumor suppression by transforming growth factor beta 1 transgene expression. Proc Natl Acad Sci U S A (1995) 2.07
Ultrastructural studies of vasopressin effect on isolated perfused renal collecting tubules of the rabbit. J Cell Biol (1968) 2.06
A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. Proc Natl Acad Sci U S A (1990) 2.03
Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. Proc Natl Acad Sci U S A (1988) 2.03
Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation. Proc Natl Acad Sci U S A (1990) 2.01
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Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type beta transforming growth factor. Cancer Res (1986) 1.97
Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells. J Biol Chem (1988) 1.93
Polyadenylylated RNA complementary to a mouse retrovirus-like multigene family is rapidly and specifically induced by epidermal growth factor stimulation of quiescent cells. Proc Natl Acad Sci U S A (1982) 1.89
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Melanoma, growth factors, acanthosis nigricans, the sign of Leser-Trélat, and multiple acrochordons. A possible role for alpha-transforming growth factor in cutaneous paraneoplastic syndromes. N Engl J Med (1987) 1.66
Elevated cyclooxygenase-2 levels in Min mouse adenomas. Gastroenterology (1996) 1.65
Transforming growth factor type beta regulation of actin mRNA. J Cell Physiol (1986) 1.62
Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model. Cancer Res (1987) 1.61
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Altered [125I]epidermal growth factor binding and receptor distribution in psoriasis. J Invest Dermatol (1986) 1.56
Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia. J Exp Med (1991) 1.55
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Biochemical and biological differences between E7 oncoproteins of the high- and low-risk human papillomavirus types are determined by amino-terminal sequences. J Virol (1991) 1.50
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Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice. Cell Growth Differ (1998) 1.48
The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma. J Leukoc Biol (2000) 1.48
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Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching. Mol Biol Cell (1999) 1.46
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Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta. J Cell Biol (1988) 1.44
Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1. Proc Natl Acad Sci U S A (1995) 1.43
Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways. Proc Natl Acad Sci U S A (1991) 1.43
Mouse embryos contain polypeptide growth factor(s) capable of inducing a reversible neoplastic phenotype in nontransformed cells in culture. J Cell Physiol (1982) 1.43
Type beta transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval. Proc Natl Acad Sci U S A (1985) 1.42
Transgenic mice as a model to study the role of TGF-beta-related molecules in hair follicles. Genes Dev (1993) 1.40
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Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth Differ (1993) 1.33
Vascular remodeling in primary pulmonary hypertension. Potential role for transforming growth factor-beta. Am J Pathol (1994) 1.32
RhoB is stabilized by transforming growth factor beta and antagonizes transcriptional activation. J Biol Chem (1998) 1.31
Infectious mononucleosis: continuous suspension culture of peripheral blood leucocytes. Nature (1968) 1.31
Studies in cranial suture biology: Part I. Increased immunoreactivity for TGF-beta isoforms (beta 1, beta 2, and beta 3) during rat cranial suture fusion. J Bone Miner Res (1997) 1.29
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Studies on the mechanisms by which transforming growth factor-beta (TGF-beta) protects against allergic encephalomyelitis. Antagonism between TGF-beta and tumor necrosis factor. J Immunol (1993) 1.27
Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling. J Biol Chem (1998) 1.27
Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma. Am J Surg (1999) 1.27
Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1. J Biol Chem (2000) 1.25
Some characteristics of a Ca2+ dependent ATPase activity associated with a group of erythrocyte membrane proteins which form fibrils. Biochim Biophys Acta (1970) 1.25
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