Published in AJNR Am J Neuroradiol on September 16, 1993
Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment. Neurology (1999) 9.86
Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI. Neurology (2005) 5.02
Rates of hippocampal atrophy correlate with change in clinical status in aging and AD. Neurology (2000) 4.89
Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET). Proc Natl Acad Sci U S A (2001) 3.86
3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease. Brain (2007) 3.53
Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD. Eur J Nucl Med Mol Imaging (2005) 3.32
MRI patterns of atrophy associated with progression to AD in amnestic mild cognitive impairment. Neurology (2007) 3.24
The cortical signature of prodromal AD: regional thinning predicts mild AD dementia. Neurology (2008) 2.91
Memory impairment, but not cerebrovascular disease, predicts progression of MCI to dementia. Neurology (2004) 2.63
Atlas-based hippocampus segmentation in Alzheimer's disease and mild cognitive impairment. Neuroimage (2005) 2.51
Medial temporal lobe atrophy predicts Alzheimer's disease in patients with minor cognitive impairment. J Neurol Neurosurg Psychiatry (2002) 2.41
Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal. Neurobiol Aging (2008) 2.25
Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease. Ann Neurol (1998) 1.86
Tracking Alzheimer's disease. Ann N Y Acad Sci (2007) 1.78
Clearance systems in the brain-implications for Alzheimer disease. Nat Rev Neurol (2015) 1.75
Modifiable factors that alter the size of the hippocampus with ageing. Nat Rev Neurol (2012) 1.71
Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease. Alzheimers Dement (2011) 1.59
Hippocampal atrophy on MRI in frontotemporal lobar degeneration and Alzheimer's disease. J Neurol Neurosurg Psychiatry (2005) 1.53
Does mild cognitive impairment increase the risk of developing postoperative cognitive dysfunction? Am J Surg (2010) 1.51
Clinical trials in mild cognitive impairment: lessons for the future. J Neurol Neurosurg Psychiatry (2005) 1.47
Robust and conventional neuropsychological norms: diagnosis and prediction of age-related cognitive decline. Neuropsychology (2008) 1.41
Cerebral ventricular changes associated with transitions between normal cognitive function, mild cognitive impairment, and dementia. Alzheimer Dis Assoc Disord (2007) 1.35
Brain atrophy associated with baseline and longitudinal measures of cognition. Neurobiol Aging (2009) 1.31
Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease. Alzheimers Dement (2014) 1.28
Comparison of gray matter and metabolic reduction in mild Alzheimer's disease using FDG-PET and voxel-based morphometric MR studies. Eur J Nucl Med Mol Imaging (2005) 1.27
What is the functional significance of chronic stress-induced CA3 dendritic retraction within the hippocampus? Behav Cogn Neurosci Rev (2006) 1.26
Temporal lobe rating scale: application to Alzheimer's disease and frontotemporal dementia. J Neurol Neurosurg Psychiatry (2001) 1.26
In vivo assessment of amyloid-β deposition in nondemented very elderly subjects. Ann Neurol (2013) 1.17
Biomarkers in translational research of Alzheimer's disease. Neuropharmacology (2010) 1.11
Comparison of the diagnostic performance of FDG-PET and VBM-MRI in very mild Alzheimer's disease. Eur J Nucl Med Mol Imaging (2006) 1.08
The apolipoprotein E gene, attention, and brain function. Neuropsychology (2002) 1.05
Chronic stress enhances ibotenic acid-induced damage selectively within the hippocampal CA3 region of male, but not female rats. Neuroscience (2004) 1.03
Visual rating of medial temporal lobe metabolism in mild cognitive impairment and Alzheimer's disease using FDG-PET. Eur J Nucl Med Mol Imaging (2005) 1.03
Medial temporal lobe atrophy in stroke patients: relation to pre-existing dementia. J Neurol Neurosurg Psychiatry (1998) 0.99
Critical issues for successful immunotherapy in Alzheimer's disease: development of biomarkers and methods for early detection and intervention. CNS Neurol Disord Drug Targets (2009) 0.97
Metyrapone reveals that previous chronic stress differentially impairs hippocampal-dependent memory. Stress (2001) 0.92
Cerebrovascular reactivity to carbon dioxide in Alzheimer's disease. J Alzheimers Dis (2013) 0.91
The prediction and prevention of Alzheimer's disease--towards a research agenda. J Psychiatry Neurosci (1999) 0.90
Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research. Neurobiol Aging (2009) 0.89
Mild cognitive impairment: historical development and summary of research. Dialogues Clin Neurosci (2004) 0.86
Dementia in Down's syndrome: an MRI comparison with Alzheimer's disease in the general population. J Neurodev Disord (2013) 0.83
The role of the entorhinal cortex in extinction: influences of aging. Neural Plast (2008) 0.82
Automatic analysis of medial temporal lobe atrophy from structural MRIs for the early assessment of Alzheimer disease. Med Phys (2009) 0.82
Patterns of compensation and vulnerability in normal subjects at risk of Alzheimer's disease. J Alzheimers Dis (2013) 0.80
Mild cognitive impairment. Continuum (Minneap Minn) (2013) 0.79
Cross-validation of brain structural biomarkers and cognitive aging in a community-based study. Int Psychogeriatr (2012) 0.79
Tract-based spatial statistics: application to mild cognitive impairment. Biomed Res Int (2014) 0.79
Amyloid, neurodegeneration, and small vessel disease as predictors of dementia in the oldest-old. Neurology (2014) 0.79
Translation of imaging biomarkers from clinical research to healthcare. Z Gerontol Geriatr (2017) 0.78
Early initiation of hormone therapy in menopausal women is associated with increased hippocampal and posterior cingulate cholinergic activity. J Clin Endocrinol Metab (2011) 0.78
Predicting Progression from Mild Cognitive Impairment to Alzheimer's Dementia Using Clinical, MRI, and Plasma Biomarkers via Probabilistic Pattern Classification. PLoS One (2016) 0.78
Voxel Level Survival Analysis of Grey Matter Volume and Incident Mild Cognitive Impairment or Alzheimer's Disease. J Alzheimers Dis (2015) 0.78
Effects of healthy ageing on precision and binding of object location in visual short term memory. Psychol Aging (2014) 0.78
Age-related mild cognitive deficit: a ready-to-use concept? Dialogues Clin Neurosci (2003) 0.76
Magnetic resonance spectroscopy in the prediction of early conversion from amnestic mild cognitive impairment to dementia: a prospective cohort study. BMJ Open (2011) 0.76
Regional Hippocampal Atrophy and Higher Levels of Plasma Amyloid-Beta Are Associated With Subjective Memory Complaints in Nondemented Elderly Subjects. J Gerontol A Biol Sci Med Sci (2016) 0.75
Distinct patterns of medial temporal impairment in degenerative dementia: a brain SPECT perfusion study in Alzheimer's disease and frontotemporal dementia. Eur J Nucl Med Mol Imaging (2013) 0.75
Studies in the biochemistry of micro-organisms: The metabolic products of the Penicillium brevi-compactum series. Biochem J (1932) 11.42
Confidential inquiry into quality of care before admission to intensive care. BMJ (1998) 11.32
The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry (1982) 10.83
Studies in the biochemistry of micro-organisms: The metabolic products of Penicillium Charlesii G. Smith. Biochem J (1934) 10.22
Studies in the biochemistry of micro-organisms: The metabolic products of Aspergillus terreus Thom. A new mould metabolic product-terrein. Biochem J (1935) 7.74
Studies in the biochemistry of micro-organisms: The metabolic products of Aspergillus terreus Thom. Part II. Two new chlorine-containing mould metabolic products, geodin and erdin. Biochem J (1936) 6.60
Hours, volume, and type of work of preregistration house officers. BMJ (1990) 5.68
A family intervention to delay nursing home placement of patients with Alzheimer disease. A randomized controlled trial. JAMA (1996) 4.80
Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nat Neurosci (1998) 4.76
Development of cognitive instruments for use in clinical trials of antidementia drugs: additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord (1997) 4.31
A phase I evaluation of the safety and immunogenicity of vaccination with recombinant gp160 in patients with early human immunodeficiency virus infection. Military Medical Consortium for Applied Retroviral Research. N Engl J Med (1991) 4.23
Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology (2007) 3.97
Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET). Proc Natl Acad Sci U S A (2001) 3.86
Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord (1997) 3.77
Studies in the biochemistry of micro-organisms: The metabolic products of Byssochlamys fulva Olliver and Smith. Biochem J (1933) 3.74
The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease. Neuroscience (2000) 3.40
Hippocampal formation glucose metabolism and volume losses in MCI and AD. Neurobiol Aging (2001) 3.25
Cardiovascular and catecholamine responses to laryngoscopy with and without tracheal intubation. Br J Anaesth (1987) 3.05
Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals. Am J Psychiatry (1998) 3.02
Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes. J Exp Med (1987) 3.02
Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen. J Exp Med (1988) 2.85
Mild cognitive impairment in the elderly: predictors of dementia. Neurology (1991) 2.83
Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer's disease. Neurobiol Aging (2000) 2.80
Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial. Neurology (2009) 2.76
Serotonin in aging, late-life depression, and Alzheimer's disease: the emerging role of functional imaging. Neuropsychopharmacology (1998) 2.70
Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease. Neurobiol Aging (1997) 2.68
Postoperative wound infection: a computer analysis. Br J Surg (1971) 2.67
Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease. Neurology (2008) 2.66
Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease. Neurobiol Aging (1997) 2.66
Behavioral symptoms in Alzheimer's disease: phenomenology and treatment. J Clin Psychiatry (1987) 2.65
PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie. J Gen Virol (1994) 2.63
Hippocampal damage and memory impairments as possible early brain complications of type 2 diabetes. Diabetologia (2007) 2.60
Sources and types of referral to a haematology department. Health Trends (1992) 2.48
Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease. Ann Neurol (1998) 2.48
Symptoms after primary immunisation with DTP and with DT vaccine. Lancet (1984) 2.48
Purchasing 'legal highs' on the Internet--is there consistency in what you get? QJM (2010) 2.43
Selection of an obstetric data base for a microcomputer and its use for on-line production of birth notification forms, discharge summaries and perinatal audit. Br J Obstet Gynaecol (1983) 2.36
Does cerebral blood flow decline in healthy aging? A PET study with partial-volume correction. J Nucl Med (2000) 2.33
Hippocampal volume losses in minimally impaired elderly. Lancet (1995) 2.26
A comprehensive support program: effect on depression in spouse-caregivers of AD patients. Gerontologist (1995) 2.26
Reduced hippocampal metabolism in MCI and AD: automated FDG-PET image analysis. Neurology (2005) 2.24
Preliminary evidence for brain complications in obese adolescents with type 2 diabetes mellitus. Diabetologia (2010) 2.20
Echocardiographic measurement of the normal adult right ventricle. Br Heart J (1986) 2.16
Global Deterioration Scale (GDS). Psychopharmacol Bull (1988) 2.14
Studies in the biochemistry of micro-organisms: Fumaryl-dl-alanine (fumaromono-dl-alanide), a metabolic product of Penicillium resticulosum sp.nov. Biochem J (1942) 2.13
Should we patch corneal abrasions? A meta-analysis. J Fam Pract (1998) 2.12
Epidural anaesthesia and analgesia: better outcome after major surgery?. Growing evidence suggests so. BMJ (1999) 2.10
Reversible restoration of the birefringence of cold-treated, isolated mitotic apparatus of surf clam eggs with chick brain tubulin. Nature (1974) 2.08
Neurological impairment in violent schizophrenic inpatients. Am J Psychiatry (1989) 2.07
Science, medicine, and the future: Pharmacogenetics. BMJ (2000) 2.06
Testicular fixation following torsion of the spermatic cord--does it guarantee prevention of recurrent torsion events? J Urol (2006) 2.02
Early marker for Alzheimer's disease: the atrophic hippocampus. Lancet (1989) 2.02
A complex between the MHC class I homologue encoded by human cytomegalovirus and beta 2 microglobulin. Nature (1990) 2.01
Antibiotics and surgery for vesicoureteric reflux: a meta-analysis of randomised controlled trials. Arch Dis Child (2003) 1.99
Neuropsychological prediction of decline to dementia in nondemented elderly. J Geriatr Psychiatry Neurol (1999) 1.93
Alzheimer disease: measuring loss of cerebral gray matter with MR imaging. Radiology (1991) 1.92
Accuracy of burn size estimation and subsequent fluid resuscitation prior to arrival at the Yorkshire Regional Burns Unit. A three year retrospective study. Burns (1999) 1.92
Individual risk factors for hip osteoarthritis: obesity, hip injury, and physical activity. Am J Epidemiol (1998) 1.90
Oesophageal apoplexy. Lancet (1974) 1.88
MRI of entorhinal cortex in mild Alzheimer's disease. Lancet (1999) 1.86
Ward design in relation to postoperative wound infection. I. Br Med J (1971) 1.85
National symptom surveillance using calls to a telephone health advice service--United Kingdom, December 2001-February 2003. MMWR Morb Mortal Wkly Rep (2004) 1.82
The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma. Gut (2005) 1.73
Use of capillary blood in measurement of arterial PO2. Br Med J (1968) 1.73
Neurofilaments are transported rapidly but intermittently in axons: implications for slow axonal transport. J Neurosci (2000) 1.73
An intervention that delays institutionalization of Alzheimer's disease patients: treatment of spouse-caregivers. Gerontologist (1993) 1.72
Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease. Diabetes (2001) 1.70
Genetic analysis of the human cytochrome P450 CYP2C9 locus. Pharmacogenetics (1996) 1.67
Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Am J Cardiol (2001) 1.66
Changing epidemiology and ecology of highly pathogenic avian H5N1 influenza viruses. Avian Dis (2007) 1.65
ABC of intensive care. Criteria for admission. BMJ (1999) 1.65
Repeatability and validity of an upper limb and neck discomfort questionnaire: the utility of the standardized Nordic questionnaire. Occup Med (Lond) (1999) 1.62
CT diagnostic features of Alzheimer disease: importance of the choroidal/hippocampal fissure complex. AJNR Am J Neuroradiol (1990) 1.62
Raised mortality from lung cancer and high sex ratios of births associated with industrial pollution. Br J Ind Med (1985) 1.62
CYT387, a selective JAK1/JAK2 inhibitor: in vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients. Leukemia (2009) 1.61
Physicians' knowledge of cost: the case of diagnostic tests. Inquiry (1976) 1.60
Female sexuality in multiple sclerosis: the multidimensional nature of the problem and the intervention. Acta Neurol Scand (2010) 1.57
Genetics of cognition: outline of a collaborative twin study. Twin Res (2001) 1.56
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Brief Cognitive Rating Scale (BCRS). Psychopharmacol Bull (1988) 1.55
Memory function in normal aging. Neurology (1992) 1.55
Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer. Carcinogenesis (2003) 1.54