N J Severs

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia. Circulation 1997 3.33
2 Downregulation of immunodetectable connexin43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricle. Circulation 1998 2.26
3 Spatiotemporal relation between gap junctions and fascia adherens junctions during postnatal development of human ventricular myocardium. Circulation 1994 2.21
4 Altered connexin expression in human congestive heart failure. J Mol Cell Cardiol 2001 2.15
5 Reduced content of connexin43 gap junctions in ventricular myocardium from hypertrophied and ischemic human hearts. Circulation 1993 2.05
6 Altered patterns of gap junction distribution in ischemic heart disease. An immunohistochemical study of human myocardium using laser scanning confocal microscopy. Am J Pathol 1991 1.93
7 Gap junctions and connexin expression in human suburothelial interstitial cells. BJU Int 2002 1.75
8 The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system. J Cell Sci 1993 1.65
9 Loss of desmoplakin isoform I causes early onset cardiomyopathy and heart failure in a Naxos-like syndrome. J Med Genet 2006 1.64
10 Dissociated spatial patterning of gap junctions and cell adhesion junctions during postnatal differentiation of ventricular myocardium. Circ Res 1997 1.63
11 Nuclear pore absence from areas of close association between nucleus and vacuole in synchronous yeast cultures. J Ultrastruct Res 1976 1.55
12 Altered patterns of cardiac intercellular junction distribution in hypertrophic cardiomyopathy. Heart 1996 1.41
13 Low serum cholesterol and suicide. Lancet 1992 1.39
14 Distinct patterns of dystrophin organization in myocyte sarcolemma and transverse tubules of normal and diseased human myocardium. Circulation 2000 1.37
15 Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart. Circ Res 1998 1.34
16 Mechanisms of acute eosinophil mobilization from the bone marrow stimulated by interleukin 5: the role of specific adhesion molecules and phosphatidylinositol 3-kinase. J Exp Med 1998 1.25
17 The gap-junctional protein connexin40 is elevated in patients susceptible to postoperative atrial fibrillation. Circulation 2001 1.24
18 Nuclear pore formation and the cell cycle in Saccharomyces cerevisiae. Exp Cell Res 1977 1.21
19 Detection of microdomains in biomembranes. An appraisal of recent developments in freeze-fracture cytochemistry. Biochim Biophys Acta 1983 1.21
20 Chamber-related differences in connexin expression in the human heart. J Mol Cell Cardiol 1999 1.19
21 Gap junction remodeling in hypertrophied left ventricles of aortic-banded rats: prevention by angiotensin II type 1 receptor blockade. J Mol Cell Cardiol 2001 1.19
22 Connexin45 (alpha 6) expression delineates an extended conduction system in the embryonic and mature rodent heart. Dev Genet 1999 1.18
23 Remodeling of gap junctional coupling in hypertrophied right ventricles of rats with monocrotaline-induced pulmonary hypertension. Circ Res 2000 1.18
24 Individual gap junction plaques contain multiple connexins in arterial endothelium. Circ Res 1999 1.14
25 Connexin45, a major connexin of the rabbit sinoatrial node, is co-expressed with connexin43 in a restricted zone at the nodal-crista terminalis border. J Histochem Cytochem 1999 1.12
26 Gap junction distribution in adult mammalian myocardium revealed by an anti-peptide antibody and laser scanning confocal microscopy. J Cell Sci 1991 1.09
27 Upregulation of connexin43 gap junctions during early stages of human coronary atherosclerosis. Arterioscler Thromb Vasc Biol 1995 1.09
28 Expression, localization, and activity of tissue factor pathway inhibitor in normal and atherosclerotic human vessels. Arterioscler Thromb Vasc Biol 2000 1.07
29 Age-related alteration of gap junction distribution and connexin expression in rat aortic endothelium. J Histochem Cytochem 2000 1.06
30 Analysis of membrane structure in the transitional epithelium of rat urinary bladder. 2. The discoidal vesicles and Golgi apparatus: their role in luminal membrane biogenesis. J Ultrastruct Res 1979 1.05
31 Correlation of ultrastructure and function in calcium-tolerant myocytes isolated from the adult rat heart. J Ultrastruct Res 1982 1.03
32 Immunolabelling patterns of gap junction connexins in the developing and mature rat heart. Anat Embryol (Berl) 1992 1.02
33 Gap junction localization and connexin expression in cytochemically identified endothelial cells of arterial tissue. J Histochem Cytochem 1997 1.02
34 Validation of immunohistochemical quantification in confocal scanning laser microscopy: a comparative assessment of gap junction size with confocal and ultrastructural techniques. J Histochem Cytochem 1993 1.01
35 The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium. Gene Ther 1999 1.01
36 Evidence for a distinct gap-junctional phenotype in ventricular conduction tissues of the developing and mature avian heart. Circ Res 1993 1.00
37 Connexin expression in Huntington's diseased human brain. Cell Biol Int 1998 1.00
38 Morphometric analysis of the isolated calcium-tolerant cardiac myocyte. Organelle volumes, sarcomere length, plasma membrane surface folds, and intramembrane particle density and distribution. Cell Tissue Res 1985 0.98
39 Analysis of the rat liver gap junction protein: clarification of anomalies in its molecular size. Proc R Soc Lond B Biol Sci 1988 0.97
40 Association of granulocyte-macrophage colony-stimulating factor with the crystalloid granules of human eosinophils. Blood 1995 0.96
41 Upregulation of connexin43 gap junctions between smooth muscle cells after balloon catheter injury in the rat carotid artery. Arterioscler Thromb Vasc Biol 1997 0.95
42 Impedance measurements and connexin expression in human detrusor muscle from stable and unstable bladders. BJU Int 2003 0.93
43 Multiple connexin expression in regenerating arterial endothelial gap junctions. Arterioscler Thromb Vasc Biol 2000 0.92
44 Species-specific difference in distribution of voltage-gated L-type Ca(2+) channels of cardiac myocytes. Am J Physiol Cell Physiol 2000 0.91
45 Induction of bladder cancer in rats by fractionated intravesicular doses of N-methyl-N-nitrosourea. Br J Cancer 1982 0.91
46 Heat stress contributes to the enhancement of cardiac mitochondrial complex activity. Am J Pathol 2001 0.90
47 Smooth muscle cells express granulocyte-macrophage colony-stimulating factor in the undiseased and atherosclerotic human coronary artery. Arterioscler Thromb Vasc Biol 1997 0.90
48 Plasma membrane cholesterol in myocardial muscle and capillary endothelial cells. Distribution of filipin-induced deformations in freeze-fracture. Eur J Cell Biol 1981 0.90
49 Immunogold-labeled L-type calcium channels are clustered in the surface plasma membrane overlying junctional sarcoplasmic reticulum in guinea-pig myocytes-implications for excitation-contraction coupling in cardiac muscle. J Mol Cell Cardiol 2000 0.89
50 Failure of filipin to detect cholesterol-rich domains in smooth muscle plasma membrane. Nature 1983 0.89
51 Isolated calcium-tolerant myocytes and the calcium paradox: an ultrastructural comparison. Eur Heart J 1983 0.88
52 Presence of the Kv1.5 K(+) channel in the sinoatrial node. J Histochem Cytochem 2000 0.88
53 Cardiac myocyte gap junctions: evidence for a major connexon protein with an apparent relative molecular mass of 70,000. J Cell Sci 1990 0.87
54 Membranes of matrix-vesicles in early developing dentine. A freeze fracture study. Cell Biol Int Rep 1982 0.87
55 The structure of the contractile apparatus in ultrarapidly frozen smooth muscle: freeze-fracture, deep-etch, and freeze-substitution studies. J Struct Biol 1995 0.87
56 Sex differences in connexin-43 expression in left ventricles of aging rats. Physiol Res 2005 0.86
57 Caveolar bands and the effects of sterol-binding agents in vascular smooth muscle plasma membrane. Single and double labeling with filipin and tomatin in the aorta, pulmonary artery, and vena cava. Lab Invest 1986 0.86
58 Comparison of the response of myocardial muscle and capillary endothelial nuclear membranes to the cholesterol probe filipin. J Submicrosc Cytol 1982 0.86
59 Regional differentiation of desmin, connexin43, and connexin45 expression patterns in rat aortic smooth muscle. Arterioscler Thromb Vasc Biol 2001 0.86
60 Structural, biochemical and functional effects of distending pressure in the human saphenous vein: implications for bypass grafting. Coron Artery Dis 1998 0.86
61 Differential expression of connexin43 and desmin defines two subpopulations of medial smooth muscle cells in the human internal mammary artery. Arterioscler Thromb Vasc Biol 1999 0.85
62 Display of low density lipoprotein receptors is clustered, not dispersed, in fibroblast and hepatocyte plasma membranes. Arterioscler Thromb 1991 0.85
63 Heterogeneity of myocardial sleeve morphology and gap junctions in canine superior vena cava. Circulation 2001 0.85
64 The Wolff-Parkinson-White syndrome: the cellular substrate for conduction in the accessory atrioventricular pathway. Eur Heart J 1994 0.85
65 Frozen-surface replicas of rat bladder luminal membrane. J Microsc 1977 0.85
66 Cardiac arrhythmogenesis and the gap junction. J Mol Cell Cardiol 1995 0.84
67 Spatial relationship of the C-terminal domains of dystrophin and beta-dystroglycan in cardiac muscle support a direct molecular interaction at the plasma membrane interface. Circ Res 1998 0.84
68 Dystrophin and the cardiomyocyte membrane cytoskeleton in the healthy and failing heart. Heart Fail Rev 2000 0.84
69 Cardiac gap junctions in rat ventricle: localization using site-directed antibodies and laser scanning confocal microscopy. Cardioscience 1990 0.83
70 Gap junction connexon configuration in rapidly frozen myocardium and isolated intercalated disks. J Cell Biol 1984 0.83
71 Cholesterol-induced changes of type VIII collagen expression and distribution in carotid arteries of rabbit. Arterioscler Thromb Vasc Biol 1999 0.82
72 A simplified method for the rapid isolation of cardiac intercalated discs. Tissue Cell 1983 0.82
73 No effect of histamine on human bronchial epithelial cell permeability and tight junctional integrity in vitro. Eur Respir J 1994 0.82
74 Localization of cholesterol in the Golgi apparatus of cardiac muscle cells. Experientia 1981 0.81
75 Intercellular junctions and the cardiac intercalated disk. Adv Myocardiol 1985 0.81
76 An interpretive freeze-fracture study of plant cell nuclear pore complexes. J Ultrastruct Res 1975 0.81
77 Superior qualities of University of Wisconsin solution for ex vivo preservation of the pig heart. J Thorac Cardiovasc Surg 1992 0.81
78 Dystrophin is not a specific component of the cardiac costamere. Circ Res 1997 0.81
79 Comparison of connexin 43, 40 and 45 expression patterns in the developing human and mouse hearts. Cell Commun Adhes 2001 0.81
80 Analysis of membrane structure in the transitional epithelium of rat urinary bladder. 3. Localization of cholesterol using filipin and digitonin. J Ultrastruct Res 1981 0.81
81 Connexin make-up of endothelial gap junctions in the rat pulmonary artery as revealed by immunoconfocal microscopy and triple-label immunogold electron microscopy. J Histochem Cytochem 1999 0.80
82 Analysis of membrane structure in the transitional epithelium of rat urinary bladder. 1. The luminal membrane. J Ultrastruct Res 1978 0.80
83 Cholesterol distribution and structural differentiation in the sarcoplasmic reticulum of rat cardiac muscle cells. A freeze-fracture cytochemical investigation. Cell Tissue Res 1982 0.80
84 The pathway of atrial natriuretic peptide release--from cell to plasma. Cardioscience 1991 0.79
85 Spatial distribution of dihydropyridine receptors in the plasma membrane of guinea pig cardiac myocytes investigated by correlative confocal microscopy and label-fracture electron microscopy. J Electron Microsc (Tokyo) 1997 0.79
86 Connexon rearrangement in cardiac gap junctions: evidence for cytoskeletal control? Cell Tissue Res 1984 0.79
87 Co-localization of dystrophin and beta-dystroglycan demonstrated in en face view by double immunogold labeling of freeze-fractured skeletal muscle. J Histochem Cytochem 1998 0.79
88 Gap junction density in human myometrium at term revealed by an anti-peptide antibody and laser scanning confocal microscopy. Folia Histochem Cytobiol 1993 0.79
89 Angiotensin II receptor type 1 mRNA is upregulated in atria of patients with end-stage heart failure. J Mol Cell Cardiol 1997 0.79
90 Robert Feulgen Prize Lecture. Distribution and role of gap junctions in normal myocardium and human ischaemic heart disease. Histochemistry 1993 0.78
91 Ultrastructural analysis of skeletal muscle. Microvascular dimensions and basement membrane thickness in chronic heart failure. Eur Heart J 1994 0.78
92 Effects of calcium on the migration and recruitment of macrophages and macrophage-derived foam cells. FASEB J 1996 0.78
93 Repression of the macrophage scavenger receptor in macrophage-smooth muscle cell heterokaryons. Arterioscler Thromb Vasc Biol 1995 0.78
94 Inverted logic. Nature 1984 0.78
95 Freeze-fracture morphology and quantification of human bronchial epithelial tight junctions. Am J Respir Cell Mol Biol 1992 0.78
96 Connexin43 gap junction levels during development of the thoracic aorta are temporally correlated with elastic laminae deposition and increased blood pressure. Cell Biol Int 1997 0.78
97 Identification of two further gap-junctional proteins, connexin40 and connexin45, in human myometrial smooth muscle cells at term. Eur J Cell Biol 1998 0.78
98 Dephosphorylation agents depress gap junctional communication between rat cardiac cells without modifying the Connexin43 phosphorylation degree. Gen Physiol Biophys 2000 0.78
99 Rough endoplasmic reticulum in the adult mammalian cardiac muscle cell. J Submicrosc Cytol 1985 0.78
100 Stretch-induced centrifugal movement of atrial specific granules--a preparatory step in atrial natriuretic peptide secretion. J Mol Cell Cardiol 1989 0.77
101 Influence of native and modified lipoproteins on migration of mouse peritoneal macrophages and the effect of the antioxidants vitamin E and Probucol. Eur J Cell Biol 1996 0.77
102 Structural alterations of airway epithelial tight junctions in cystic fibrosis: comparison of transplant and postmortem tissue. Am J Respir Cell Mol Biol 1993 0.77
103 The induction of urothelial hyperplasia by methyl methanesulphonate and ethyl methanesulphonate. Br J Cancer 1983 0.77
104 Ultrastructure of the sarcolemma and intercalated disc in isolated rat myocytes. Basic Res Cardiol 1985 0.77
105 Coated vesicles are implicated in the post-fusion retrieval of the membrane of rat atrial secretory granules. Cell Tissue Res 1992 0.77
106 Development of the distal end and Tomes' processes of ameloblasts observed by freeze-fracture and ultrathin section electron microscopy. J Anat 1991 0.76
107 Expression of connexin43 gap junctions between cultured vascular smooth muscle cells is dependent upon phenotype. Cell Tissue Res 1993 0.76
108 Connexin45 is the first connexin to be expressed in the central conduction system of the mouse heart. Exp Clin Cardiol 2001 0.76
109 Effect of neuromimetics upon the release of atrial natriuretic peptide granules: are multiple pathways involved in secretion? J Cell Physiol 1996 0.76
110 Relative susceptibility of endothelium and myocardial cells to ischaemia-reperfusion injury. Acta Physiol Scand 1997 0.75
111 The "promoting" activity of methyl methanesulphonate in rat bladder carcinogenesis. Br J Cancer 1984 0.75
112 Lipoprotein receptors on macrophages and smooth muscle cells. Curr Top Pathol 1993 0.75
113 Inverse relationship between connexin43 and desmin expression in cultured porcine aortic smooth muscle cells. Eur J Cell Biol 1999 0.75
114 Multiple connexins localized to individual gap-junctional plaques in human myometrial smooth muscle. Microsc Res Tech 2001 0.75
115 Matrix constituents of early developing bone examined by freeze fracture. Cell Biol Int Rep 1983 0.75
116 A simple technique for the examination of urothelial surface morphology by transmission electron microscopy: platinum-carbon replicas of critical point dried bladder tissue. J Microsc 1980 0.75
117 Quantitative immunoconfocal analysis of human myometrial gap junction connexin43 in relation to steroid hormone concentrations at term labour. Hum Reprod 1997 0.75
118 Freeze-fracture analysis of plasma membranes in Duchenne muscular dystrophy. A study using cultured skin fibroblasts. J Neurol Sci 1983 0.75
119 Double labeling of lipoprotein receptors in fibroblast cell surface replicas. J Ultrastruct Res 1984 0.75
120 Stretch and anesthetic dependency of atrial natriuretic peptide release demonstrated by an ultrastructural assay. J Cell Physiol 1993 0.75
121 Nuclear envelope inclusions demonstrated by freeze-fracture. Cytobios 1976 0.75
122 Morphometric analysis of calcium-tolerant myocytes isolated from the adult rat heart. Adv Myocardiol 1985 0.75
123 Arrested exocytosis of atrial secretory granules. J Mol Cell Cardiol 1990 0.75
124 A comparison between the epithelial tight junction morphology of human extrapulmonary bronchi and rat trachea. Eur Respir J 1994 0.75
125 Nuclear pores. Can they expand and contrast to regulate nucleocytoplasmic exchange? Experientia 1978 0.75
126 Plasmalemmal vesicles and the effects of sterol-binding agents in rabbit aortic endothelium. J Cell Sci 1986 0.75
127 Nuclear envelope transport capacity and the cell cycle in yeast (Saccharomyces cerevisiae). Cytobios 1977 0.75