M J de Leon

Author PubWeight™ 101.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry 1982 10.83
2 Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome. JAMA 2001 5.13
3 Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology 2007 3.97
4 The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease. Neuroscience 2000 3.40
5 Hippocampal formation glucose metabolism and volume losses in MCI and AD. Neurobiol Aging 2001 3.25
6 Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer's disease. Neurobiol Aging 2000 2.80
7 Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease. Neurology 2008 2.66
8 Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease. Ann Neurol 1998 2.48
9 Hippocampal volume losses in minimally impaired elderly. Lancet 1995 2.26
10 Reduced hippocampal metabolism in MCI and AD: automated FDG-PET image analysis. Neurology 2005 2.24
11 Global Deterioration Scale (GDS). Psychopharmacol Bull 1988 2.14
12 Altered glucose metabolism in microvessels from patients with Alzheimer's disease. Ann Neurol 1989 2.08
13 Early marker for Alzheimer's disease: the atrophic hippocampus. Lancet 1989 2.02
14 Alzheimer disease: measuring loss of cerebral gray matter with MR imaging. Radiology 1991 1.92
15 MRI of entorhinal cortex in mild Alzheimer's disease. Lancet 1999 1.86
16 Relationships between regional neuronal loss and neurofibrillary changes in the hippocampal formation and duration and severity of Alzheimer disease. J Neuropathol Exp Neurol 1997 1.67
17 CT diagnostic features of Alzheimer disease: importance of the choroidal/hippocampal fissure complex. AJNR Am J Neuroradiol 1990 1.62
18 Hippocampal atrophy in normal aging. An association with recent memory impairment. Arch Neurol 1993 1.49
19 Volumetric analysis of the pre-frontal regions: findings in aging and schizophrenia. Psychiatry Res 2001 1.38
20 Hippocampal atrophy in early Alzheimer's disease: anatomic specificity and validation. Psychiatr Q 1993 1.33
21 Hippocampal formation size predicts declining memory performance in normal aging. Neurology 1996 1.33
22 Topography of cross-sectional and longitudinal glucose metabolic deficits in Alzheimer's disease. Pathophysiologic implications. Arch Neurol 1992 1.33
23 Atrophy rate in medial temporal lobe during progression of Alzheimer disease. Neurology 2004 1.31
24 Hippocampal formation size in normal human aging: a correlate of delayed secondary memory performance. Learn Mem 1999 1.31
25 Cortisol differentially affects memory in young and elderly men. Behav Neurosci 2001 1.19
26 Leukoencephalopathy in normal and pathologic aging: 2. MRI of brain lucencies. AJNR Am J Neuroradiol 1986 1.18
27 Computed tomography and positron emission transaxial tomography evaluations of normal aging and Alzheimer's disease. J Cereb Blood Flow Metab 1983 1.13
28 MRI volume of the amygdala: a reliable method allowing separation from the hippocampal formation. Psychiatry Res 1999 1.13
29 Positron emission tomographic studies of aging and Alzheimer disease. AJNR Am J Neuroradiol 1983 1.13
30 Neuronal and volume loss in CA1 of the hippocampal formation uniquely predicts duration and severity of Alzheimer disease. Brain Res 1998 1.12
31 Positron emission tomography and computed tomography assessments of the aging human brain. J Comput Assist Tomogr 1984 1.00
32 Volumetric measurement of the hippocampus, the anterior cingulate cortex, and the retrosplenial granular cortex of the rat using structural MRI. Brain Res Brain Res Protoc 2002 0.99
33 Reduced incidence of left-handedness in clinically diagnosed dementia of the Alzheimer type. Neurobiol Aging 1986 0.98
34 Abnormal cortisol response in Alzheimer's disease linked to hippocampal atrophy. Lancet 1988 0.98
35 Duration of neurofibrillary changes in the hippocampal pyramidal neurons. Brain Res 1998 0.97
36 Atrophy of hippocampal formation subdivisions correlates with stage and duration of Alzheimer disease. Dementia 1995 0.97
37 Central amine metabolism in Alzheimer's disease: in vivo relationship to cognitive deficit. Neurobiol Aging 1981 0.97
38 Leukoencephalopathy in normal and pathologic aging: 1. CT of brain lucencies. AJNR Am J Neuroradiol 1986 0.92
39 Mortality and temporal course of probable Alzheimer's disease: a 5-year prospective study. Int Psychogeriatr 1996 0.92
40 Measurement of medial temporal lobe atrophy in diagnosis of Alzheimer's disease. Lancet 1993 0.92
41 Age-related changes in brain: II. Positron emission tomography of frontal and temporal lobe glucose metabolism in normal subjects. Psychiatr Q 1995 0.92
42 Vascular fibrosis and calcification in the hippocampus in aging, Alzheimer disease, and Down syndrome. Acta Neuropathol 2001 0.90
43 Volumetric structural magnetic resonance imaging (MRI) of the rat hippocampus following kainic acid (KA) treatment. Brain Res 2002 0.90
44 Early detection of Alzheimer's disease with PET imaging. Neurodegener Dis 2010 0.90
45 Longitudinal course of normal aging and progressive dementia of the Alzheimer's type: a prospective study of 106 subjects over a 3.6 year mean interval. Prog Neuropsychopharmacol Biol Psychiatry 1986 0.89
46 Correlations between computerised tomographic changes and behavioural deficits in senile dementia. Lancet 1979 0.89
47 The stage specific temporal course of Alzheimer's disease: functional and behavioral concomitants based upon cross-sectional and longitudinal observation. Prog Clin Biol Res 1989 0.89
48 Age-related changes in brain: I. Magnetic resonance imaging measures of temporal lobe volumes in normal subjects. Psychiatr Q 1995 0.88
49 Positron emission tomography studies of normal aging: a replication of PET III and 18-FDG using PET VI and 11-CDG. Neurobiol Aging 1987 0.88
50 Prefrontal N-acetylaspartate and poststroke recovery: a longitudinal proton spectroscopy study. AJNR Am J Neuroradiol 2007 0.85
51 Longitudinal CT study of parenchymal brain changes in glioma survivors. AJNR Am J Neuroradiol 1988 0.83
52 Ventricular volume and cognitive deficit: a computed tomographic study. Radiology 1983 0.83
53 Hippocampal cerebrospinal fluid spaces on MR imaging: Relationship to aging and Alzheimer disease. AJNR Am J Neuroradiol 2006 0.82
54 Regional correlation of PET and CT in senile dementia of the Alzheimer type. AJNR Am J Neuroradiol 1983 0.81
55 Positron emission tomography in the study of aging and senile dementia. Neurobiol Aging 1980 0.81
56 Imaging and cerebrospinal fluid biomarkers in the search for Alzheimer's disease mechanisms. Neurodegener Dis 2013 0.80
57 Nutrient patterns and brain biomarkers of Alzheimer's disease in cognitively normal individuals. J Nutr Health Aging 2015 0.80
58 Parenchymal CT correlates of senile dementia (Alzheimer disease): loss of gray-white matter discriminability. AJNR Am J Neuroradiol 1981 0.80
59 Abnormal temporal lobe response in Alzheimer's disease during cognitive processing as measured by 11C-2-deoxy-D-glucose and PET. J Cereb Blood Flow Metab 1987 0.79
60 Hippocampal atrophy correlates with severe cognitive impairment in elderly patients with suspected normal pressure hydrocephalus. J Neurol Neurosurg Psychiatry 1994 0.79
61 Elevated cerebellar glucose metabolism in microvascular white matter disease: normal aging and Alzheimer's disease. J Cereb Blood Flow Metab 1988 0.78
62 Novel pharmacologic approaches to the treatment of senile dementia of the Alzheimer's type (SDAT). Psychopharmacol Bull 1983 0.78
63 The differential diagnosis of Alzheimer's disease. Cerebral atrophy versus normal pressure hydrocephalus. Neuroimaging Clin N Am 1995 0.78
64 Focal dilation and paradoxical collapse of cortical fissures and sulci in patients with normal-pressure hydrocephalus. J Neurosurg 1998 0.77
65 Fibrillar amyloid-beta affects neurofibrillary changes but only in neurons already involved in neurofibrillary degeneration. Acta Neuropathol 2001 0.77
66 The concept of FDG-PET endophenotype in Alzheimer's disease. Neurol Sci 2011 0.77
67 Periventricular lucencies in the CT scans of aged and demented patients. Biol Psychiatry 1986 0.77
68 Wandering and parietal signs in senile dementia of Alzheimer's type. Neuropsychobiology 1984 0.76
69 Principal axes and surface fitting methods for three-dimensional image registration. J Nucl Med 1993 0.76
70 Periventricular high signal lesions and signal void on magnetic resonance imaging in hydrocephalus. Diagnostic and prognostic significance. Acta Radiol Suppl 1986 0.75
71 Nonspecific leukoencephalopathy associated with aging. Neuroimaging Clin N Am 1995 0.75
72 Positron emission tomography in dementia. Adv Neurol 1983 0.75
73 The perihippocampal fissures: normal anatomy and disease states. Radiographics 1998 0.75
74 Dilatation of the lateral part of the transverse fissure of the brain in Alzheimer's disease. Acta Neurobiol Exp (Wars) 1993 0.75
75 Computed tomography in aging and senile dementia of the Alzheimer type. Adv Neurol 1983 0.75
76 Relationship between cognition and mood in geriatric depression. Psychopharmacol Bull 1982 0.75
77 Positron emission tomography of hydrocephalus. Metabolic effects of shunt procedures. Acta Radiol Suppl 1986 0.75
78 Imaging the brain in dementia: expensive and futile? AJNR Am J Neuroradiol 1998 0.75
79 Significance of age-related white matter lesions. Stroke 1988 0.75
80 The relationship between psychiatric assessments and cognitive test measures in mild to moderately cognitively impaired elderly [proceedings]. Psychopharmacol Bull 1981 0.75