Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 8384939)

Published in Circulation on April 01, 1993

Authors

H Schunkert1, B Jackson, S S Tang, F J Schoen, J F Smits, C S Apstein, B H Lorell

Author Affiliations

1: Charles A. Dana Research Institute, Boston.

Associated clinical trials:

Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI) (RASTAVI) | NCT03201185

Articles citing this

Modifier genes for hypertrophic cardiomyopathy. Curr Opin Cardiol (2002) 1.47

Cardiac GPCRs: GPCR signaling in healthy and failing hearts. Biochim Biophys Acta (2007) 1.45

A prospective, double-blind, randomized controlled trial of the angiotensin-converting enzyme inhibitor Ramipril In Aortic Stenosis (RIAS trial). Eur Heart J Cardiovasc Imaging (2015) 1.44

Augmented phosphorylation of cardiac troponin I in hypertensive heart failure. J Biol Chem (2011) 1.38

Glycolytic inhibition: effects on diastolic relaxation and intracellular calcium handling in hypertrophied rat ventricular myocytes. J Clin Invest (1995) 1.13

Diastolic dysfunction, cardiovascular aging, and the anesthesiologist. Anesthesiol Clin (2009) 0.91

Angiotensin II formation in the intact human heart. Predominance of the angiotensin-converting enzyme pathway. J Clin Invest (1995) 0.86

Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure. Heart Fail Rev (2010) 0.84

Effect of statin therapy on disease progression in pediatric ADPKD: design and baseline characteristics of participants. Contemp Clin Trials (2011) 0.83

Endothelin and angiotensin II stimulation of Na+-H+ exchange is impaired in cardiac hypertrophy. J Clin Invest (1997) 0.82

Role of protein kinase C-delta in angiotensin II induced cardiac fibrosis. Biochem Biophys Res Commun (2009) 0.82

Alteration of growth responses in established cardiac pressure overload hypertrophy in rats with aortic banding. J Clin Invest (1995) 0.79

Diverse factors influencing angiotensin metabolism during ACE inhibition: insights from molecular biology and genetic studies. Br Heart J (1994) 0.77

Echocardiographic evaluation of diastolic heart failure. Australas J Ultrasound Med (2015) 0.75

Radionuclide imaging of neurohormonal system of the heart. Theranostics (2015) 0.75

Benazepril and subclinical feline hypertrophic cardiomyopathy: a prospective, blinded, controlled study. Can Vet J (2006) 0.75

Articles by these authors

Myocarditis. A histopathologic definition and classification. Am J Cardiovasc Pathol (1987) 5.33

Maternal levels of plasma human immunodeficiency virus type 1 RNA and the risk of perinatal transmission. Women and Infants Transmission Study Group. N Engl J Med (1999) 5.05

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nat Med (1999) 4.85

Evaluation of a quality assurance program for quantitation of human immunodeficiency virus type 1 RNA in plasma by the AIDS Clinical Trials Group virology laboratories. J Clin Microbiol (1996) 4.81

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest (2000) 4.79

Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nat Med (2001) 3.89

A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure. Vesnarinone Trial Investigators. N Engl J Med (1998) 3.86

Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure. Circ Res (1987) 3.86

A mouse model of familial hypertrophic cardiomyopathy. Science (1996) 3.69

Fruit and vegetable consumption and prevention of cancer: the Black Churches United for Better Health project. Am J Public Health (1999) 3.50

Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation (2001) 3.47

Prevention of bioprosthetic heart valve calcification by ethanol preincubation. Efficacy and mechanisms. Circulation (1997) 3.38

Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. N Engl J Med (1994) 3.11

Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature (1996) 2.94

Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques. Circulation (1999) 2.73

An abnormal Ca(2+) response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy. J Clin Invest (2000) 2.56

Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome. Nat Med (2001) 2.46

Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure? Circ Res (2001) 2.38

Chronic myocardial infarction in the mouse: cardiac structural and functional changes. Cardiovasc Res (1999) 2.25

Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II. Am J Physiol (1992) 2.20

Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies. Am J Physiol (1999) 2.19

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proc Natl Acad Sci U S A (1997) 2.15

An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation (2001) 2.09

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation. J Clin Invest (1990) 2.07

The infarcted myocardium: simply dead tissue, or a lively target for therapeutic interventions. Cardiovasc Res (1999) 2.06

The creatine kinase system in normal and diseased human myocardium. N Engl J Med (1985) 2.06

Refinement of the alpha aminooleic acid bioprosthetic valve anticalcification technique. Ann Thorac Surg (1997) 2.05

Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy. Proc Natl Acad Sci U S A (1997) 2.02

Rat proximal tubule cell line transformed with origin-defective SV40 DNA: autocrine ANG II feedback. Am J Physiol (1999) 2.02

Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice. J Clin Invest (1999) 2.02

Smooth-muscle differentiation in stromal cells of malignant and non-malignant breast tissues. Int J Cancer (1988) 2.01

Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization. Biotechnol Bioeng (1999) 2.00

Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research. Circulation (1997) 2.00

Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro. Am J Pathol (2001) 1.96

Real-time imaging of apoptotic cell-membrane changes at the single-cell level in the beating murine heart. Nat Med (2001) 1.91

Reaction of aortic lysyl oxidase with beta-aminopropionitrile. J Biol Chem (1983) 1.90

Contractile reserve and intracellular calcium regulation in mouse myocytes from normal and hypertrophied failing hearts. Circ Res (2000) 1.85

Minority and nonminority pediatricians' care of minority and poor children. Arch Pediatr Adolesc Med (2000) 1.83

Human coronary transplantation-associated arteriosclerosis. Evidence for a chronic immune reaction to activated graft endothelial cells. Am J Pathol (1991) 1.82

Use of virologic assays for detection of human immunodeficiency virus in clinical trials: recommendations of the AIDS Clinical Trials Group Virology Committee. J Clin Microbiol (1993) 1.78

Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure. Circulation (1987) 1.78

Functional living trileaflet heart valves grown in vitro. Circulation (2000) 1.77

Neuroprotection mediated by changes in the endothelial actin cytoskeleton. J Clin Invest (2000) 1.76

Infusion of light chains from patients with cardiac amyloidosis causes diastolic dysfunction in isolated mouse hearts. Circulation (2001) 1.73

Circumferential stress and matrix metalloproteinase 1 in human coronary atherosclerosis. Implications for plaque rupture. Arterioscler Thromb Vasc Biol (1996) 1.71

Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction. Circ Res (2001) 1.70

The contribution of assay variation and biological variation to the total variability of plasma HIV-1 RNA measurements. The Women Infant Transmission Study Clinics. Virology Quality Assurance Program. AIDS (1999) 1.70

Sporadic cryptosporidiosis in children. Lancet (1983) 1.69

Estrogen modulates AT1 receptor gene expression in vitro and in vivo. Circulation (1998) 1.69

Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. Proc Natl Acad Sci U S A (1998) 1.68

Glucose-insulin-potassium (GIK) for acute myocardial infarction: a negative study with a positive value. Cardiovasc Drugs Ther (1999) 1.63

A rapid manual method for CD4+ T-cell quantitation for use in developing countries. AIDS (1993) 1.63

Induced expression of endothelial-leukocyte adhesion molecules in human cardiac allografts. Transplantation (1991) 1.62

Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. Circ Res (1993) 1.60

Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60

Power spectrum analysis of heart rate variability in human cardiac transplant recipients. Circulation (1989) 1.60

Determinations of levels of human immunodeficiency virus type 1 RNA in plasma: reassessment of parameters affecting assay outcome. TUBE Meeting Workshop Attendees. Technology Utilization for HIV-1 Blood Evaluation and Standardization in Pediatrics. J Clin Microbiol (1998) 1.58

Treatment with growth hormone enhances contractile reserve and intracellular calcium transients in myocytes from rats with postinfarction heart failure. Circulation (1999) 1.58

Recovery of human immunodeficiency virus from ocular tissues in patients with acquired immune deficiency syndrome. Ophthalmology (1988) 1.57

Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin. Circ Res (2001) 1.56

Committee report. Nucleic acid amplification testing of blood donors for transfusion-transmitted infectious diseases: Report of the Interorganizational Task Force on Nucleic Acid Amplification Testing of Blood Donors. Transfusion (2000) 1.54

Angiotensin converting enzyme (ACE), characterization by 125I-MK351A binding studies of plasma and tissue ACE during variation of salt status in the rat. J Hypertens (1986) 1.54

Structure-dependent dynamic mechanical behavior of fibrous caps from human atherosclerotic plaques. Circulation (1991) 1.53

Serial echocardiographic-Doppler assessment of left ventricular geometry and function in rats with pressure-overload hypertrophy. Chronic angiotensin-converting enzyme inhibition attenuates the transition to heart failure. Circulation (1995) 1.52

Amelanotic lentigo maligna melanoma: a unique case presentation. Dermatol Surg (1999) 1.51

Cardiac-specific overexpression of cyclin-dependent kinase 2 increases smaller mononuclear cardiomyocytes. Circ Res (2001) 1.50

Surgical management of carcinoid heart disease. Ann Thorac Surg (1991) 1.50

IgA nephropathy: a syndrome of uniform morphology, diverse clinical features and uncertain prognosis. Clin Nephrol (1977) 1.49

Derivation and characterization of an efficiently myocarditic reovirus variant. J Virol (1989) 1.49

Rapid expression of heat shock protein in the rabbit after brief cardiac ischemia. J Clin Invest (1991) 1.48

Pathology of explanted cryopreserved allograft heart valves: comparison with aortic valves from orthotopic heart transplants. J Thorac Cardiovasc Surg (1998) 1.45

Partnering with African American churches to achieve better health: lessons learned during the Black Churches United for Better Health 5 a day project. J Cancer Educ (2000) 1.45

Dilated cardiomyopathy in two transgenic mouse lines expressing activated G protein alpha(q): lack of correlation between phospholipase C activation and the phenotype. J Mol Cell Cardiol (2001) 1.43

Pericardial effusion in patients with cancer: outcome with contemporary management strategies. Heart (1996) 1.43

Failure to maintain a low ADP concentration impairs diastolic function in hypertrophied rat hearts. Circulation (1997) 1.42

Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41

Trojan particles: large porous carriers of nanoparticles for drug delivery. Proc Natl Acad Sci U S A (2002) 1.41

Pressure overload induces severe hypertrophy in mice treated with cyclosporine, an inhibitor of calcineurin. Circ Res (1999) 1.41

Blood and albumin cardioplegia preserve endothelium-dependent microvascular responses. Ann Thorac Surg (1993) 1.41

Phaeochromocytoma and hypertrophic cardiomyopathy: apparent suppression of symptoms and noradrenaline secretion by calcium-channel blockade. Lancet (1983) 1.41

Functions of vascular wall cells related to development of transplantation-associated coronary arteriosclerosis. Transplant Proc (1989) 1.40

Cardiac risk factor management. Experience of an outpatient hypertension clinic. Med J Aust (1991) 1.40

Impaired cell shortening and relengthening with increased pacing frequency are intrinsic to the senescent mouse cardiomyocyte. J Mol Cell Cardiol (2000) 1.40

Alpha-smooth muscle actin is transiently expressed in embryonic rat cardiac and skeletal muscles. Differentiation (1988) 1.39

Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7  TeV. Phys Rev Lett (2011) 1.39

Targeted ablation of the murine alpha-tropomyosin gene. Circ Res (1997) 1.38

Long-term methicillin-resistant Staphylococcus aureus (MRSA) carriage and tagging of patient records. J Hosp Infect (1997) 1.38

Biologic determinants of dystrophic calcification and osteocalcin deposition in glutaraldehyde-preserved porcine aortic valve leaflets implanted subcutaneously in rats. Am J Pathol (1983) 1.37

Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice. Acta Physiol Scand (2001) 1.37

Myocardial healing and repair after experimental infarction in the rabbit. Circ Res (1983) 1.35

Implications of echocardiographically assisted diagnosis of pericardial tamponade in contemporary medical patients: detection before hemodynamic embarrassment. J Am Coll Cardiol (1991) 1.35

Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34

Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis. Am J Pathol (2001) 1.33

Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32

Gender differences in molecular remodeling in pressure overload hypertrophy. J Am Coll Cardiol (1999) 1.32

Toxicology and biocompatibility of bioglasses. J Biomed Mater Res (1981) 1.31

Comparison of two murine models of familial hypertrophic cardiomyopathy. Circ Res (2001) 1.30

Protective effect of increased glycolytic substrate against systolic and diastolic dysfunction and increased coronary resistance from prolonged global underperfusion and reperfusion in isolated rabbit hearts perfused with erythrocyte suspensions. Circ Res (1991) 1.30