Randomized study assessing the effect of digoxin withdrawal in patients with mild to moderate chronic congestive heart failure: results of the PROVED trial. PROVED Investigative Group.

PubWeight™: 2.49‹?› | Rank: Top 2%

🔗 View Article (PMID 8409069)

Published in J Am Coll Cardiol on October 01, 1993

Authors

B F Uretsky1, J B Young, F E Shahidi, L G Yellen, M C Harrison, M K Jolly

Author Affiliations

1: Presbyterian University Hospital, Pittsburgh, Pennsylvania 15213.

Articles citing this

Digoxin and reduction in mortality and hospitalization in heart failure: a comprehensive post hoc analysis of the DIG trial. Eur Heart J (2005) 4.37

Digoxin reduces 30-day all-cause hospital admission in older patients with chronic systolic heart failure. Am J Med (2013) 3.46

Drug therapy in chronic heart failure. Postgrad Med J (2003) 2.73

Cardiology--II: Treatment of heart failure and atrial fibrillation and arrhythmias. BMJ (1994) 2.01

Quantitative evaluation of drug or device effects on ventricular remodeling as predictors of therapeutic effects on mortality in patients with heart failure and reduced ejection fraction: a meta-analytic approach. J Am Coll Cardiol (2010) 1.93

Digoxin and mortality in atrial fibrillation: a prospective cohort study. Eur J Clin Pharmacol (2007) 1.66

Digoxin use and lower 30-day all-cause readmission for Medicare beneficiaries hospitalized for heart failure. Am J Med (2013) 1.61

The management of congestive heart failure. Postgrad Med J (1997) 1.16

Role of mitochondrial dysfunction in cardiac glycoside toxicity. J Mol Cell Cardiol (2010) 1.14

Drug treatment in heart failure. BMJ (2000) 1.13

Effect of oral digoxin in high-risk heart failure patients: a pre-specified subgroup analysis of the DIG trial. Eur J Heart Fail (2013) 1.06

Dronedarone-digoxin interaction in PALLAS: A foxglove connection? Glob Cardiol Sci Pract (2015) 0.95

Heart rate variability in left ventricular dysfunction and heart failure: effects and implications of drug treatment. Br Heart J (1994) 0.86

Atrial fibrillation is associated with a lower exercise capacity in male chronic heart failure patients. Heart (1997) 0.85

Effects of discontinuation of digoxin versus continuation at low serum digoxin concentrations in chronic heart failure. Am J Cardiol (2007) 0.81

Therapeutic ranges of serum digoxin concentrations in patients with heart failure. Am J Cardiol (2012) 0.80

The economics of cardiac failure. J R Soc Med (1996) 0.80

Pharmacological treatment of chronic heart failure. Heart Fail Rev (2006) 0.79

Inotropic agents for heart failure: what if digoxin increases mortality? Br Heart J (1994) 0.78

Digitalis in heart failure! Still applicable? Z Kardiol (2005) 0.78

Heart failure therapy at the turn of the century. Heart Fail Rev (2001) 0.77

Clinical and Therapeutic Profiles of Heart Failure Patients admitted to a Tertiary Hospital, Aseer Region, Saudi Arabia. Sultan Qaboos Univ Med J (2011) 0.77

Outpatient management of congestive heart failure. Tex Heart Inst J (1998) 0.77

Acute decompensated heart failure update. Curr Cardiol Rev (2015) 0.77

Digoxin in management of heart failure in children: Should it be continued or relegated to the history books? Ann Pediatr Cardiol (2009) 0.76

Temporary practice pause then resumption (TPPR) study design: an extension of the withdrawal study design to complementary and alternative medicine mind and body interventions (CAM-MABI). J Altern Complement Med (2013) 0.76

Clinical case studies in heart failure management. Br J Clin Pharmacol (1999) 0.75

Digoxin: A systematic review in atrial fibrillation, congestive heart failure and post myocardial infarction. World J Cardiol (2015) 0.75

Use of a simplified nomogram to individualize digoxin dosing versus standard dosing practices in patients with heart failure. Pharmacotherapy (2014) 0.75

To dig or not to dig. Trans Am Clin Climatol Assoc (1998) 0.75

Cardioversion of atrial fibrillation. Postgrad Med J (1996) 0.75

Positive inotropes in heart failure: a review article. Heart Asia (2012) 0.75

The effect of high dose digoxin on cytokines in healthy dogs. Mediators Inflamm (2002) 0.75

Myocardial phenotype changes in heart failure: cellular and subcellular adaptations and their functional significance. Br Heart J (1994) 0.75

Digoxin toxicity: Case for retiring its use in elderly patients? Can Fam Physician (2016) 0.75

Effect of gender difference in management of heart failure patients in aseer, saudi arabia. Heart Views (2011) 0.75

Young at Heart: Pioneering Approaches to Model Nonischaemic Cardiomyopathy with Induced Pluripotent Stem Cells. Stem Cells Int (2016) 0.75

Management of Patients Admitted with Acute Decompensated Heart Failure. Ochsner J (2015) 0.75

Chronic Heart Failure Clinical Practice Guidelines' Class 1-A Pharmacologic Recommendations: Start-to-End Synergistic Drug Therapy? ASEAN Heart J (2016) 0.75

Digoxin withdrawal in patients with heart failure. J Am Coll Cardiol (1994) 0.75

Recent advances in cardiology. Postgrad Med J (1994) 0.75

Heart Failure: A Class Review of Pharmacotherapy. P T (2017) 0.75

Left ventricular ejection fraction as therapeutic target: is it the ideal marker? Heart Fail Rev (2017) 0.75

Korean Guidelines for Diagnosis and Management of Chronic Heart Failure. Korean Circ J (2017) 0.75

Articles by these authors

Withdrawal of digoxin from patients with chronic heart failure treated with angiotensin-converting-enzyme inhibitors. RADIANCE Study. N Engl J Med (1993) 7.19

Anthracycline-induced cardiotoxicity. Ann Intern Med (1996) 4.31

A new, simplified and accurate method for determining ejection fraction with two-dimensional echocardiography. Circulation (1981) 3.49

Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD). J Am Coll Cardiol (1996) 3.47

Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST). Circulation (2001) 3.15

Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes (1981) 2.89

Cause of death in clinical research: time for a reassessment? J Am Coll Cardiol (1999) 2.36

Team management of patients with heart failure: A statement for healthcare professionals from The Cardiovascular Nursing Council of the American Heart Association. Circulation (2000) 2.22

Partial left ventriculectomy for dilated cardiomyopathy: is this an alternative to transplantation? J Thorac Cardiovasc Surg (2001) 2.22

High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound. Circulation (2001) 2.13

Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart. Circulation (1996) 2.10

Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays. Circulation (2000) 2.04

Fasting, feeding and regulation of the sympathetic nervous system. N Engl J Med (1978) 2.04

Ventilatory and heart rate responses to exercise : better predictors of heart failure mortality than peak oxygen consumption. Circulation (1999) 1.88

Effects of glucocorticoids on energy metabolism and food intake in humans. Am J Physiol (1996) 1.86

Early results with partial left ventriculectomy. J Thorac Cardiovasc Surg (1997) 1.78

Contemporary management of patients with left ventricular systolic dysfunction. Results from the Study of Patients Intolerant of Converting Enzyme Inhibitors (SPICE) Registry. Eur Heart J (1999) 1.76

Suppression of sympathetic nervous system during fasting. Science (1977) 1.71

Preoperative risk factors for right ventricular failure after implantable left ventricular assist device insertion. Ann Thorac Surg (1999) 1.63

A general population survey of rest cramps. Age Ageing (1994) 1.57

Device-based change in left ventricular shape: a new concept for the treatment of dilated cardiomyopathy. J Thorac Cardiovasc Surg (2001) 1.56

Effect of diet and cold exposure on norepinephrine turnover in brown adipose tissue of the rat. J Clin Invest (1982) 1.56

Rhabdomyolysis and renal injury with lovastatin use. Report of two cases in cardiac transplant recipients. JAMA (1988) 1.55

Results of partial left ventriculectomy for dilated cardiomyopathy: hemodynamic, clinical and echocardiographic observations. J Am Coll Cardiol (2000) 1.55

B-type natriuretic peptide levels are not a surrogate marker for invasive hemodynamics during management of patients with severe heart failure. Am Heart J (2005) 1.51

Natural history and patterns of current practice in heart failure. The Studies of Left Ventricular Dysfunction (SOLVD) Investigators. J Am Coll Cardiol (1993) 1.49

Assessment of pulsed Doppler echocardiography in detection and quantification of aortic and mitral regurgitation. Br Heart J (1980) 1.44

Catecholamine modulation of rapid potassium shifts during exercise. N Engl J Med (1985) 1.43

One hundred patients with the HeartMate left ventricular assist device: evolving concepts and technology. J Thorac Cardiovasc Surg (1998) 1.42

Effects of cyclosporine therapy on plasma lipoprotein levels. JAMA (1989) 1.40

Relationship of urinary serotonin excretion to cigarette smoking and respiratory symptoms. The Normative Aging Study. Chest (1992) 1.40

Evaluation of the effects of aspirin combined with angiotensin-converting enzyme inhibitors in patients with coronary artery disease. Am J Med (2000) 1.39

Infective discitis as an uncommon but important cause of back pain in older people. Age Ageing (2000) 1.39

Attenuation of waiting time mortality with heterotopic heart transplantation. Ann Thorac Surg (1992) 1.39

Basic mechanisms in congestive heart failure. Recognizing the role of proinflammatory cytokines. Chest (1994) 1.38

The neglected hospital wheelchair. Br Med J (Clin Res Ed) (1985) 1.36

The prevalence of women with breast implants in the United States--1989. J Clin Epidemiol (1995) 1.35

Stimulation of the sympathetic nervous system during sucrose feeding. Nature (1977) 1.32

Reduced sympathetic nervous system responsivity associated with the relaxation response. Science (1982) 1.31

Value and safety of cardiac catheterization during active infective endocarditis. Am J Cardiol (1979) 1.28

Effect of diet and cold exposure on norepinephrine turnover in pancreas and liver. Am J Physiol (1979) 1.27

Acute cocaine poisoning. Importance of treating seizures and acidosis. Am J Med (1983) 1.26

Pretransplantation risk factors for death after heart transplantation: a multiinstitutional study. The Transplant Cardiologists Research Database Group. J Heart Lung Transplant (1993) 1.26

Activation of the complement system by recombinant tissue plasminogen activator. J Am Coll Cardiol (1987) 1.25

Adrenergic modulation of extrarenal potassium disposal. N Engl J Med (1980) 1.17

Left ventricular diastolic performance at rest and during exercise in patients with coronary artery disease. Assessment with first-pass radionuclide angiography. Circulation (1981) 1.15

End-systolic volume index at 90 to 180 minutes into reperfusion therapy for acute myocardial infarction is a strong predictor of early and late mortality. The Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-I Angiographic Investigators. Circulation (1997) 1.15

Pulsed Doppler echocardiographic detection of right-sided valve regurgitation. Experimental results and clinical significance. Am J Cardiol (1981) 1.14

Prinzmetal's angina during 5-fluorouracil chemotherapy. Am J Med (1987) 1.12

Sympathoadrenal system and regulation of thermogenesis. Am J Physiol (1984) 1.12

Effect of dietary fat on sympathetic nervous system activity in the rat. J Clin Invest (1983) 1.11

The breast implant controversy. Arthritis Rheum (1994) 1.11

Catecholamines and intermediary metabolism. Clin Endocrinol Metab (1977) 1.11

Enhanced plasma norepinephrine response to upright posture and oral glucose administration in elderly human subjects. Metabolism (1980) 1.10

Recurrent infective endocarditis: analysis of predisposing factors and clinical features. Am J Med (1979) 1.09

Acute starvation protects mice against Listeria monocytogenes. Infect Immun (1980) 1.06

Diminished sympathetic nervous system activity in genetically obese (ob/ob) mouse. Am J Physiol (1983) 1.05

Insensitivity of noninvasive tests to detect coronary artery vasculopathy after heart transplant. Am J Cardiol (1991) 1.05

Relation of obesity and diet to sympathetic nervous system activity. Hypertension (1991) 1.04

Birth weight, climate at birth and the risk of obesity in adult life. Int J Obes Relat Metab Disord (2000) 1.04

Effect of age on body composition and resting metabolic rate. Am J Physiol (1990) 1.03

Impaired in vivo insulin clearance in patients with severe target-cell resistance to insulin. Diabetes (1982) 1.02

Dissociation of sympathetic nervous system and adrenal medullary responses. Am J Physiol (1984) 1.02

The primary care stroke gap. Br J Gen Pract (2001) 1.00

Does successful bridging with the implantable left ventricular assist device affect cardiac transplantation outcome? J Thorac Cardiovasc Surg (1996) 0.99

A low sympathoadrenal activity is associated with body weight gain and development of central adiposity in Pima Indian men. Obes Res (1997) 0.98

Ethnic differences in sympathetic nervous system-mediated energy expenditure. Am J Physiol (1991) 0.98

Sympathoadrenal activity in fasting pregnant rats. Dissociation of adrenal medullary and sympathetic nervous system responses. J Clin Invest (1979) 0.98

Hypogammaglobulinemia following cardiac transplantation: a link between rejection and infection. J Heart Lung Transplant (2001) 0.98

Initiation, duration and dissipation of diet-induced changes in sympathetic nervous system activity in the rat. Metabolism (1982) 0.97

On the mechanism of the effects of potassium restriction on blood pressure and renal sodium retention. Am J Kidney Dis (1998) 0.97

Senior House Officer training in geriatric medicine. Age Ageing (1987) 0.97

The HOPE study. Ramipril lowered cardiovascular risk, but vitamin E did not. Cleve Clin J Med (2000) 0.96

Recurrent infective endocarditis in a drug addict. Multiple separate episodes in nine years. Chest (1979) 0.96

Reduced rearing temperature augments responses in sympathetic outflow to brown adipose tissue. J Neurosci (2000) 0.95

Recurrence of giant cell myocarditis in cardiac allograft. J Heart Lung Transplant (2001) 0.95

Familial insulin resistance with acanthosis nigricans, acral hypertrophy, and muscle cramps. N Engl J Med (1980) 0.94

General practitioners and the geriatric day hospital. Health Trends (1989) 0.94

Differential systemic arterial and venous actions and consequent cardiac effects of vasodilator drugs. Prog Cardiovasc Dis (1982) 0.94

Sympathetic nervous system responses to cold exposure and diet in rat skeletal muscle. Am J Physiol (1988) 0.94

Hypogammaglobulinemia after heart transplantation: impact of pre-emptive use of immunoglobulin replacement (CytoGam) on infection and rejection outcomes. Transpl Infect Dis (2001) 0.94

A randomized, multicenter comparison of tacrolimus and cyclosporine immunosuppressive regimens in cardiac transplantation: decreased hyperlipidemia and hypertension with tacrolimus. J Heart Lung Transplant (1999) 0.94

Beneficial effects of RheothRx injection in patients receiving thrombolytic therapy for acute myocardial infarction. Results of a randomized, double-blind, placebo-controlled trial. Circulation (1996) 0.93

Influence of insulin, sympathetic nervous system activity, and obesity on blood pressure: the Normative Aging Study. J Hypertens (1996) 0.93

Sympathetic nervous system and adrenal medullary responses to ischemic injury in mice. Am J Physiol (1983) 0.92

Diagnosis and quantification of aortic stenosis with pulsed Doppler echocardiography. Am J Cardiol (1980) 0.92

The role of the sympathoadrenal system in modulating energy expenditure. Clin Endocrinol Metab (1984) 0.92

The inverse relationship between baseline left ventricular ejection fraction and outcome of antiarrhythmic therapy: a dangerous imbalance in the risk-benefit ratio. Am Heart J (1989) 0.92

Rejection of catheters. Br Med J (Clin Res Ed) (1985) 0.92

Effects of 2-deoxy-D-glucose on the cardiac sympathetic nerves and the adrenal medulla in the rat: further evidence for a dissociation of sympathetic nervous system and adrenal medullary responses. Endocrinology (1982) 0.92

Hemodynamic effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients with class III to IV congestive heart failure. Circulation (2001) 0.92

Adverse effects of enalapril in the Studies of Left Ventricular Dysfunction (SOLVD). SOLVD Investigators. Am Heart J (1996) 0.92

Ephedrine, caffeine and aspirin: safety and efficacy for treatment of human obesity. Int J Obes Relat Metab Disord (1993) 0.91

Effect of alpha-adrenergic blockade on arrhythmias induced by acute myocardial ischemia and reperfusion in the dog. J Mol Cell Cardiol (1984) 0.91

The older cardiac transplant donor. Relation to graft function and recipient survival longer than 6 years. Circulation (1989) 0.91

Sympathoadrenal responses to acute and chronic hypoxia in the rat. J Clin Invest (1983) 0.91

"Agrobacterium yellow group" and Pseudomonas paucimobilis causing peritonitis in patients receiving continuous ambulatory peritoneal dialysis. J Clin Pathol (1985) 0.91

Comparative effects of losartan and enalapril on exercise capacity and clinical status in patients with heart failure. The Losartan Pilot Exercise Study Investigators. J Am Coll Cardiol (1997) 0.91

Why referred potential heart donors aren't used. Tex Heart Inst J (1993) 0.90