PubRank

S Khosla

Author PubWeight™ 132.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res 1998 4.24
2 beta-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin. Biochemistry 1980 3.94
3 Weekend hospitalization and additional risk of death: an analysis of inpatient data. J R Soc Med 2012 3.77
4 The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res 2000 3.38
5 Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest 2000 2.94
6 Implications of absolute fracture risk assessment for osteoporosis practice guidelines in the USA. Osteoporos Int 2008 2.74
7 Cost-effective osteoporosis treatment thresholds: the United States perspective. Osteoporos Int 2008 2.72
8 Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology 1999 2.69
9 Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone 1999 2.69
10 Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 1999 2.65
11 Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology 1999 2.27
12 Idiopathic osteoporosis--is the osteoblast to blame? J Clin Endocrinol Metab 1997 2.25
13 Epidemiology of sarcopenia. J Am Geriatr Soc 2000 1.97
14 Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption. J Clin Endocrinol Metab 1996 1.79
15 Assessing forearm fracture risk in postmenopausal women. Osteoporos Int 2009 1.71
16 Genomic imprinting in mammals: an interplay between chromatin and DNA methylation? Trends Genet 1999 1.67
17 DNA methylation is linked to deacetylation of histone H3, but not H4, on the imprinted genes Snrpn and U2af1-rs1. Mol Cell Biol 2001 1.55
18 The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated. Endocrinology 2000 1.43
19 Effect of gender on outcomes following renal artery stent placement for renovascular hypertension. Cathet Cardiovasc Diagn 1997 1.43
20 Leptin reduces ovariectomy-induced bone loss in rats. Endocrinology 2001 1.40
21 Rotational atherectomy for left anterior descending artery septal perforator stenosis. Catheter Cardiovasc Interv 1999 1.39
22 Cross-sectional versus longitudinal evaluation of bone loss in men and women. Osteoporos Int 2000 1.37
23 Survival after the diagnosis of hyperparathyroidism: a population-based study. Am J Med 1998 1.36
24 The rise and fall of primary hyperparathyroidism: a population-based study in Rochester, Minnesota, 1965-1992. Ann Intern Med 1997 1.35
25 Effects of estrogen therapy on bone marrow adipocytes in postmenopausal osteoporotic women. Osteoporos Int 2008 1.35
26 Towards a diagnostic and therapeutic consensus in male osteoporosis. Osteoporos Int 2011 1.33
27 Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines. Biochem Biophys Res Commun 1998 1.33
28 Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women. Bone 2001 1.27
29 The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group. Osteoporos Int 2014 1.27
30 Relationship of bone turnover to bone density and fractures. J Bone Miner Res 1997 1.26
31 Clinical performance of parathyroid hormone immunometric assays. Mayo Clin Proc 1992 1.22
32 Relationship of intestinal calcium absorption to 1,25-dihydroxyvitamin D [1,25(OH)2D] levels in young versus elderly women: evidence for age-related intestinal resistance to 1,25(OH)2D action. J Clin Endocrinol Metab 2000 1.22
33 Bone fragility in men--where are we? Osteoporos Int 2006 1.19
34 Beta-lactamase inactivation by mechanism-based reagents. Philos Trans R Soc Lond B Biol Sci 1980 1.17
35 Fracture risk among patients with urolithiasis: a population-based cohort study. Kidney Int 1998 1.17
36 Epidemiology of sarcopenia. Mayo Clin Proc 2000 1.17
37 Relationship of serum leptin levels with body composition and sex steroid and insulin levels in men and women. Metabolism 2000 1.17
38 Imprinted expression of neuronatin from modified BAC transgenes reveals regulation by distinct and distant enhancers. Dev Biol 2001 1.16
39 The actions and interactions of sex steroids and growth factors/cytokines on the skeleton. Mol Endocrinol 1999 1.13
40 Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology. J Bone Miner Res 2001 1.09
41 Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men. J Bone Miner Res 2001 1.04
42 Muscle strength in osteoporotic versus normal women. Osteoporos Int 1993 1.04
43 Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmenopause--a clinical research center study. J Clin Endocrinol Metab 1995 1.02
44 Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta. J Cell Biochem 2003 1.02
45 The anti-androgen hydroxyflutamide and androgens inhibit interleukin-6 production by an androgen-responsive human osteoblastic cell line. J Bone Miner Res 1999 1.02
46 Relative influence of physical activity, muscle mass and strength on bone density. Osteoporos Int 2000 1.01
47 Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line. J Cell Biochem 1998 0.98
48 Mutual antagonism of estrogen receptors alpha and beta and their preferred interactions with steroid receptor coactivators in human osteoblastic cell lines. J Endocrinol 2003 0.97
49 Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. Biochem Biophys Res Commun 2001 0.96
50 Regulation of osteoclastogenesis and RANK expression by TGF-beta1. J Cell Biochem 2001 0.96
51 Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women. J Clin Endocrinol Metab 1998 0.95
52 Use of distortion product otoacoustic emissions to assess middle ear transducers in rhesus monkeys. Am J Otol 1995 0.95
53 Sclerostin levels during growth in children. Osteoporos Int 2011 0.93
54 Relationship of femoral neck areal bone mineral density to volumetric bone mineral density, bone size, and femoral strength in men and women. Osteoporos Int 2011 0.92
55 Cytokine-specific induction of the TGF-beta inducible early gene (TIEG): regulation by specific members of the TGF-beta family. J Cell Biochem 2000 0.92
56 Role of parathyroid hormone in mediating nocturnal and age-related increases in bone resorption. J Clin Endocrinol Metab 1995 0.92
57 Prospective randomized study of effects of unopposed estrogen replacement therapy on markers of coagulation and inflammation in postmenopausal women. J Clin Endocrinol Metab 2001 0.91
58 An ultrastructural study of multifidus muscle in progressive idiopathic scoliosis. Changes resulting from a sarcolemmal defect at the myotendinous junction. J Neurol Sci 1980 0.91
59 Idiopathic osteoporosis: a heterogeneous entity. Ann Med Interne (Paris) 1998 0.91
60 Non-suppressible parathyroid hormone secretion is related to gland size in uremic secondary hyperparathyroidism. Kidney Int 1996 0.91
61 Parathyroid hormone-related protein and hypercalcemia secondary to massive mammary hyperplasia. N Engl J Med 1990 0.90
62 The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice. Bone 2007 0.90
63 In vitro and in vivo detection of somatostatin receptors in pheochromocytomas and paragangliomas. J Clin Endocrinol Metab 1992 0.89
64 Identification of multiple endocrine neoplasia, type 2 gene carriers using linkage analysis and analysis of the RET proto-oncogene. J Clin Endocrinol Metab 1994 0.89
65 Isolation and characterization of human osteoblasts from needle biopsies without in vitro culture. Osteoporos Int 2013 0.89
66 Effects of body size and skeletal site on the estimated prevalence of osteoporosis in women and men. Osteoporos Int 2000 0.89
67 Fracture risk after surgery for peptic ulcer disease: a population-based cohort study. Bone 1999 0.88
68 Fractures following thyroidectomy in women: a population-based cohort study. Bone 2000 0.86
69 Mutations in the RET protooncogene in sporadic pheochromocytomas. J Clin Endocrinol Metab 1995 0.86
70 Ongoing investigations into an implantable electromagnetic hearing aid for moderate to severe sensorineural hearing loss. Otolaryngol Clin North Am 1995 0.86
71 Response of bipotential human marrow stromal cells to insulin-like growth factors: effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes. Endocrinology 1999 0.86
72 Direct visualization of left ventricular free wall rupture by transesophageal echocardiography in acute myocardial infarction. Am Heart J 1993 0.86
73 Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform. J Cell Biochem 2001 0.85
74 Update on primary osteoporosis. Mayo Clin Proc 1997 0.84
75 Osteoporosis in men--consensus is premature. Calcif Tissue Int 2004 0.84
76 The immunosuppressant rapamycin, alone or with transforming growth factor-beta, enhances osteoclast differentiation of RAW264.7 monocyte-macrophage cells in the presence of RANK-ligand. Calcif Tissue Int 2002 0.83
77 Familial medullary thyroid cancer and prominent corneal nerves: clinical and genetic analysis. J Clin Endocrinol Metab 1995 0.83
78 Secondary osteoporosis and the risk of vertebral deformities in women. Bone 1999 0.83
79 Androgen effects on bone metabolism: recent progress and controversies. Eur J Endocrinol 1999 0.83
80 Genetic testing in medullary thyroid carcinoma syndromes: mutation types and clinical significance. Mayo Clin Proc 1997 0.83
81 Secondary osteoporosis and the risk of distal forearm fractures in men and women. Bone 2002 0.83
82 Estrogen action on bone marrow osteoclast lineage cells of postmenopausal women in vivo. Osteoporos Int 2008 0.82
83 Circulating levels of cytokines that modulate bone resorption: effects of age and menopause in women. J Bone Miner Res 1994 0.82
84 Probing chromatin structure with nuclease sensitivity assays. Methods Mol Biol 2001 0.82
85 Gorham-Stout disease (phantom bone) of the shoulder girdle. Rheumatology (Oxford) 1999 0.81
86 A defect in renal calcium conservation may contribute to the pathogenesis of postmenopausal osteoporosis. J Clin Endocrinol Metab 1998 0.81
87 Morphology and distribution of cystic cavities in the normal murine thymus. Cell Tissue Res 1986 0.81
88 Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and increased bone resorption in elderly women. Proc Assoc Am Physicians 1997 0.81
89 Effects of androgens on the insulin-like growth factor system in an androgen-responsive human osteoblastic cell line. Endocrinology 1999 0.81
90 Measurement of gene expression following cryogenic mu-CT scanning of human iliac crest biopsies. J Musculoskelet Neuronal Interact 2003 0.80
91 Novel anthropomorphic hip phantom corrects systemic interscanner differences in proximal femoral vBMD. Phys Med Biol 2014 0.80
92 Cytokine production in the bone marrow microenvironment: failure to demonstrate estrogen regulation in early postmenopausal women. J Clin Endocrinol Metab 1996 0.80
93 A fragment of the hypophosphatemic factor, MEPE, requires inducible cyclooxygenase-2 to exert potent anabolic effects on normal human marrow osteoblast precursors. J Cell Biochem 2004 0.80
94 Genomic imprinting in ruminants: allele-specific gene expression in parthenogenetic sheep. Mamm Genome 1998 0.80
95 Genetic testing in the diagnosis and management of multiple endocrine neoplasia type II. Ann Intern Med 1995 0.80
96 Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3. J Clin Endocrinol Metab 1994 0.80
97 Hepatitis C-associated osteosclerosis: an unusual syndrome of acquired osteosclerosis in adults. Am J Med 1997 0.80
98 Cardiovascular effects of nicotine: relation to deleterious effects of cigarette smoking. Am Heart J 1994 0.79
99 Management of postmenopausal osteoporosis for primary care. Menopause 1998 0.79
100 Expression of a potential metastasis suppressor gene (nm23) in thyroid neoplasms. World J Surg 1994 0.79
101 Immunoradiometric assay for intact human osteocalcin(1-49) without cross-reactivity to breakdown products. Clin Chem 1999 0.79
102 The assembly of the adult skeleton during growth and maturation: implications for senile osteoporosis. J Clin Invest 1999 0.79
103 Determinants of forearm strength in postmenopausal women. Osteoporos Int 2011 0.78
104 Primary osteoporosis in men: role of sex steroid deficiency. Mayo Clin Proc 2000 0.78
105 Bone marrow stromal cells express two distinct splice variants of ER-alpha that are regulated by estrogen. J Cell Biochem 2005 0.78
106 Autoimmune hemolytic anemia with both cold and warm autoantibodies. JAMA 1985 0.77
107 Etidronate for osteoporosis in primary biliary cirrhosis: a randomized trial. J Hepatol 2000 0.77
108 Is familial hyperparathyroidism a unique disease? Surgery 1997 0.77
109 Can vitamin D metabolite measurements facilitate a "treat-to-target" paradigm to guide vitamin D supplementation? Osteoporos Int 2015 0.77
110 Role of biochemical markers in assessment of osteoporosis. Acta Orthop Scand Suppl 1995 0.77
111 Flow-structure interaction effects on a jet emanating from a flexible nozzle. Phys Fluids (1994) 2008 0.75
112 Trabecular bone deficits among Vietnamese immigrants. Osteoporos Int 2010 0.75
113 UCS intensity and instructional set in classical eyelid conditioning: discrimination conditioning and signal-detection analysis. Can J Psychol 1969 0.75
114 Optimization of carrier frequency and duty cycle for pulse modulation of biological signals. J Biomed Eng 1980 0.75
115 ACTH and indomethacin-induced antidiuresis in low salt Brattleboro strain rats: induction and escape. Ann N Y Acad Sci 1982 0.75
116 Somatization. Indian J Med Sci 2000 0.75
117 Osteology: further debate. J Bone Miner Res 1999 0.75
118 Risk factors not addressed in antihypertensive therapy based solely on blood pressure control. J Clin Pharmacol 1993 0.75
119 Successful heart failure therapy is effective antiarrhythmia therapy. Am Heart J 1996 0.75
120 Development and characterization of a conditionally immortalized human osteoblastic cell line stably transfected with the human androgen receptor gene. J Cell Biochem 1997 0.75
121 The clinical implications of first-pass metabolism: treatment strategies for the 1990s. J Clin Pharmacol 1993 0.75