11 beta-hydroxysteroid dehydrogenase.

A role for glucocorticoids in stress-impaired reproduction: beyond the hypothalamus and pituitary. Endocrinology (2013) 0.85

Chronic inhibition of 11 β -hydroxysteroid dehydrogenase type 1 activity decreases hypertension, insulin resistance, and hypertriglyceridemia in metabolic syndrome. Biomed Res Int (2013) 0.80

Immunolocalisation of 11β-HSD-1 and -2, glucocorticoid receptor, mineralocorticoid receptor and Na+ K+-ATPase during the postnatal development of the rat epididymis. J Anat (2012) 0.76

In silico structure-function analysis of pathological variation in the HSD11B2 gene sequence. Physiol Genomics (2010) 0.76

Metabolic Coupling Determines the Activity: Comparison of 11β-Hydroxysteroid Dehydrogenase 1 and Its Coupling between Liver Parenchymal Cells and Testicular Leydig Cells. PLoS One (2015) 0.75

Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes. J Biol Chem (1982) 5.87

Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in man. Proc Natl Acad Sci U S A (1985) 3.22

HLA-linked congenital adrenal hyperplasia results from a defective gene encoding a cytochrome P-450 specific for steroid 21-hydroxylation. Proc Natl Acad Sci U S A (1984) 2.56

Structure of human steroid 21-hydroxylase genes. Proc Natl Acad Sci U S A (1986) 2.34

Evaluation of a new assay for Vi antibody in chronic carriers of Salmonella typhi. J Clin Microbiol (1980) 1.90

Cloning and expression of cDNA encoding a bovine adrenal cytochrome P-450 specific for steroid 21-hydroxylation. Proc Natl Acad Sci U S A (1984) 1.89

Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta). J Biol Chem (1989) 1.69

Nonelectrolyte diffusion across lipid bilayer systems. J Gen Physiol (1976) 1.59

Two steroid 21-hydroxylase genes are located in the murine S region. Nature (1985) 1.58

Persistence of Mycobacterium bovis in cattle. Trends Microbiol (1994) 1.56

Cloning and expression of rat cDNA encoding corticosteroid 11 beta-dehydrogenase. J Biol Chem (1989) 1.54

Frequent deletion and duplication of the steroid 21-hydroxylase genes. Am J Hum Genet (1986) 1.54

A waterborne outbreak of gastroenteritis in adults associated with Escherichia coli. Lancet (1968) 1.53

Gene conversion in salt-losing congenital adrenal hyperplasia with absent complement C4B protein. J Clin Endocrinol Metab (1986) 1.52

Identification of non-amplifying CYP21 genes when using PCR-based diagnosis of 21-hydroxylase deficiency in congenital adrenal hyperplasia (CAH) affected pedigrees. Hum Mol Genet (1996) 1.51

Time course of recovery of adrenal function in children treated for leukemia. J Pediatr (2000) 1.51

Mutation in the CYP21B gene (Ile-172----Asn) causes steroid 21-hydroxylase deficiency. Proc Natl Acad Sci U S A (1988) 1.50

Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase. Nat Genet (1995) 1.50

Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction. Circulation (1999) 1.48

Disease expression and molecular genotype in congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J Clin Invest (1992) 1.40

Vi serology in the detection of typhoid carriers. Lancet (1981) 1.39

Congenital adrenal hyperplasia. (1). N Engl J Med (1987) 1.36

A novel gene constitutively expressed in human lymphoid cells is inducible with interferon-gamma in myeloid cells. Immunogenetics (1992) 1.33

The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. J Biol Chem (1991) 1.33

Determination of functional effects of mutations in the steroid 21-hydroxylase gene (CYP21) using recombinant vaccinia virus. J Biol Chem (1990) 1.27

Molecular genetic analysis of nonclassic steroid 21-hydroxylase deficiency associated with HLA-B14,DR1. N Engl J Med (1988) 1.26

Detection of steroid 21-hydroxylase alleles using gene-specific PCR and a multiplexed ligation detection reaction. Genomics (1995) 1.26

The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex. Mol Endocrinol (1991) 1.24

Congenital adrenal hyperplasia (2). N Engl J Med (1987) 1.24

Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2. Proc Natl Acad Sci U S A (1992) 1.23

Rearrangement of 21-hydroxylase genes in disease-associated MHC supratypes. Immunogenetics (1986) 1.23

Molecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytes. Proc Natl Acad Sci U S A (1988) 1.23

Gene conversions and unequal crossovers between CYP21 (steroid 21-hydroxylase gene) and CYP21P involve different mechanisms. Proc Natl Acad Sci U S A (1995) 1.20

Cloning of cDNA encoding steroid 11 beta-hydroxylase (P450c11). Proc Natl Acad Sci U S A (1987) 1.17

Tyr-179 and Lys-183 are essential for enzymatic activity of 11 beta-hydroxysteroid dehydrogenase. Biochem Biophys Res Commun (1992) 1.16

Nonsense mutation causing steroid 21-hydroxylase deficiency. J Clin Invest (1988) 1.15

Mutations in the CYP11B1 gene causing congenital adrenal hyperplasia and hypertension cluster in exons 6, 7, and 8. Proc Natl Acad Sci U S A (1993) 1.14

A mutation (Pro-30 to Leu) in CYP21 represents a potential nonclassic steroid 21-hydroxylase deficiency allele. Mol Endocrinol (1991) 1.13

Associations between human aldosterone synthase (CYP11B2) gene polymorphisms and left ventricular size, mass, and function. Circulation (1998) 1.12

Mutations in the human CYP11B2 (aldosterone synthase) gene causing corticosterone methyloxidase II deficiency. Proc Natl Acad Sci U S A (1992) 1.09

Steroidogenic enzyme gene expression in the human heart. J Clin Endocrinol Metab (2000) 1.08

Nucleotide sequence analysis of murine 21-hydroxylase genes: mutations affecting gene expression. Proc Natl Acad Sci U S A (1986) 1.07

Angiotensin II and potassium regulate human CYP11B2 transcription through common cis-elements. Mol Endocrinol (1997) 1.07

Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1. J Clin Endocrinol Metab (1999) 1.06

Improving management of diabetic ketoacidosis in children. Pediatrics (2001) 1.03

Patterns of infection by Salmonella and Yersinia spp. in commensal house mouse (Mus musculus domesticus) populations. J Appl Microbiol (2001) 1.01

CA-Repeat polymorphism in intron 1 of HSD11B2 : effects on gene expression and salt sensitivity. Hypertension (2000) 1.01

NAD(+)-dependent isoform of 11 beta-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney. J Biol Chem (1994) 1.01

Distribution of deletions and seven point mutations on CYP21B genes in three clinical forms of steroid 21-hydroxylase deficiency. Am J Hum Genet (1991) 1.00

Restriction maps and restriction fragment length polymorphisms of the human 21-hydroxylase genes. Biochem Biophys Res Commun (1986) 1.00

Differential regulation of aldosterone synthase and 11beta-hydroxylase transcription by steroidogenic factor-1. J Mol Endocrinol (2002) 1.00

Sequence similarities between a novel putative G protein-coupled receptor and Na+/Ca2+ exchangers define a cation binding domain. Mol Endocrinol (2000) 0.98

Regulation of human CYP11B2 and CYP11B1: comparing the role of the common CRE/Ad1 element. Endocr Res (2000) 0.97

An inherited defect in aldosterone biosynthesis caused by a mutation in or near the gene for steroid 11-hydroxylase. N Engl J Med (1988) 0.97

R339H and P453S: CYP21 mutations associated with nonclassic steroid 21-hydroxylase deficiency that are not apparent gene conversions. Mol Endocrinol (1992) 0.96

CYP11B1 mutations causing non-classic adrenal hyperplasia due to 11 beta-hydroxylase deficiency. Hum Mol Genet (1997) 0.96

Associations between restriction fragment length polymorphisms detected with a probe for human 21-hydroxylase (21-OH) and two clinical forms of 21-OH deficiency. Hum Genet (1986) 0.95

Genetic analysis of the human type-1 angiotensin II receptor. Mol Endocrinol (1992) 0.94

Treatment of typhoid carriers with amoxicillin. Correlates of successful therapy. JAMA (1978) 0.94

Transcriptional regulation of human 11beta-hydroxylase (hCYP11B1). Endocrinology (2000) 0.93

Defects in the HSD11 gene encoding 11 beta-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency. J Clin Endocrinol Metab (1993) 0.92

Genomic organization and chromosomal location of the human gene encoding the B-lymphocyte activation antigen B7. Immunogenetics (1992) 0.91

CYP11B1 mutations causing congenital adrenal hyperplasia due to 11 beta-hydroxylase deficiency. J Clin Endocrinol Metab (1996) 0.90

Prenatal diagnosis of 21-hydroxylase deficiency by the complementary deoxyribonucleic acid probe for cytochrome P-450C-21OH. Am J Obstet Gynecol (1988) 0.89

Aldosterone synthesis in salt-wasting congenital adrenal hyperplasia with complete absence of adrenal 21-hydroxylase. N Engl J Med (1991) 0.88

Genotype of Yupik Eskimos with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Hum Genet (1992) 0.87

Venereal disease control in the 2nd Marine Division, Camp Lejeune, North Carolina. Mil Med (1967) 0.87

Associations between aldosterone synthase gene polymorphism and the adrenocortical function in males. J Intern Med (1998) 0.87

Prominent sex steroid metabolism in human lymphocytes. Mol Cell Endocrinol (1998) 0.87

Molecular cloning and expression of rat liver 3 alpha-hydroxysteroid dehydrogenase. Mol Endocrinol (1991) 0.87

Expression of 11 beta-hydroxysteroid dehydrogenase using recombinant vaccinia virus. Mol Endocrinol (1990) 0.85

11Beta-Hydroxysteroid Dehydrogenase Messenger Ribonucleic Acid Expression, Bioactivity and Immunoreactivity in Rat Cerebellum. J Neuroendocrinol (1990) 0.85

Immunohistochemistry of cytochrome P-450 21-hydroxylase: microscopic examination of the enzyme in the bovine adrenal cortex and kidney. Endocrinology (1988) 0.85

Variation in placental type 2 11beta-hydroxysteroid dehydrogenase activity is not related to birth weight or placental weight. Mol Cell Endocrinol (1997) 0.83

Mutations in human 11 beta-hydroxylase genes: 11 beta-hydroxylase deficiency in Jews of Morocco and corticosterone methyl-oxidase II deficiency in Jews of Iran. J Steroid Biochem Mol Biol (1993) 0.83

Prenatal diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency by allele-specific hybridization and Southern blot. Hum Genet (1994) 0.83

Gene structure and chromosomal localization of the human HSD11K gene encoding the kidney (type 2) isozyme of 11 beta-hydroxysteroid dehydrogenase. Genomics (1995) 0.82

Prepubertal gynecomastia: indirect exposure to estrogen cream. Pediatrics (2000) 0.82

Autosomal recessive familial neurohypophyseal diabetes insipidus with continued secretion of mutant weakly active vasopressin. Hum Mol Genet (1999) 0.82

Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11 beta-hydroxylase. J Biol Chem (1989) 0.82

Classical and late-onset forms of congenital adrenal hyperplasia caused by 21-OH deficiency reveal different alterations in the C4/21-OH gene region. Mol Biol Med (1986) 0.82

Adrenal 21-hydroxylase cytochrome P-450 genes within the MHC class III region. Immunol Rev (1985) 0.82

Analysis of the promoter of the NAD+ dependent 11 beta-hydroxysteroid dehydrogenase (HSD11K) gene in JEG-3 human choriocarcinoma cells. Mol Cell Endocrinol (1996) 0.82

Type 1 aldosterone synthase deficiency presenting in a middle-aged man. J Clin Endocrinol Metab (2001) 0.81

Apparent mineralocorticoid excess: genotype is correlated with biochemical phenotype. Hypertension (1996) 0.81

Alternatively spliced human type 1 angiotensin II receptor mRNAs are translated at different efficiencies and encode two receptor isoforms. Mol Endocrinol (1995) 0.81

Brucellosis in a Virginia meat-packing plant. Arch Environ Health (1974) 0.81

Molecular cloning of steroid 21-hydroxylase. Ann N Y Acad Sci (1985) 0.81

Structure of the human RD gene: a highly conserved gene in the class III region of the major histocompatibility complex. DNA (1989) 0.81

Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency. Clin Endocrinol (Oxf) (1998) 0.80

Steroid 21-hydroxylase deficiency and the major histocompatibility complex. Hum Immunol (1986) 0.80

First trimester prenatal treatment and molecular genetic diagnosis of congenital adrenal hyperplasia (21-hydroxylase deficiency). J Clin Endocrinol Metab (1990) 0.80

Use of high-performance liquid chromatography to quantitate the opiate and sugar content of illicit heroin preparations. J Chromatogr (1983) 0.80

Calcium regulates human CYP11B2 transcription. Endocr Res (1996) 0.79

Public preferences regarding rabies-prevention policies in the UK. Prev Vet Med (1999) 0.79

Genetic disorders of steroid hormone synthesis and metabolism. Baillieres Clin Endocrinol Metab (1995) 0.79

Bovine steroid 21-hydroxylase: regulation of biosynthesis. Biochemistry (1986) 0.79

Immunohistochemical localization of cytochrome P-450C21 in human adrenal cortex and its relation to endocrine function. Hum Pathol (1988) 0.79

Genomic organization of the mouse B-lymphocyte activation antigen B7. Immunogenetics (1993) 0.79

Mutants of 11beta-hydroxysteroid dehydrogenase (11-HSD2) with partial activity: improved correlations between genotype and biochemical phenotype in apparent mineralocorticoid excess. Hypertension (1999) 0.79