Published in Anticancer Drug Des on February 01, 1993
Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA. Proc Natl Acad Sci U S A (1995) 1.51
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters. Proc Natl Acad Sci U S A (1994) 1.42
Site-directed recombination via bifunctional PNA-DNA conjugates. Proc Natl Acad Sci U S A (2002) 1.32
Peptide nucleic acid (PNA) conformation and polymorphism in PNA-DNA and PNA-RNA hybrids. Proc Natl Acad Sci U S A (1993) 1.23
Transcription-mediated binding of peptide nucleic acid (PNA) to double-stranded DNA: sequence-specific suicide transcription. Nucleic Acids Res (1996) 1.09
Vector-mediated delivery of a polyamide ("peptide") nucleic acid analogue through the blood-brain barrier in vivo. Proc Natl Acad Sci U S A (1995) 1.07
Electron microscopy mapping of oligopurine tracts in duplex DNA by peptide nucleic acid targeting. Nucleic Acids Res (1994) 1.04
Synthesis and properties of DNA-PNA chimeric oligomers. Nucleic Acids Res (1996) 0.95
Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression. Proc Natl Acad Sci U S A (1999) 0.94
End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes. Nucleic Acids Res (2005) 0.90
Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistry. Int J Med Sci (2010) 0.88
Self-assembled antibody multimers through peptide nucleic acid conjugation. J Am Chem Soc (2012) 0.86
Inhibition of NF-kappa B specific transcriptional activation by PNA strand invasion. Nucleic Acids Res (1995) 0.86
Triplex formation with alpha anomers of purine-rich and pyrimidine-rich oligodeoxynucleotides. Nucleic Acids Res (1995) 0.82
The peptide nucleic acids (PNAs): introduction to a new class of probes for chromosomal investigation. Chromosoma (2004) 0.76
DNA and RNA derivatives to optimize distribution and delivery. Adv Drug Deliv Rev (2015) 0.75
Efficient silencing of gene expression by an ASON-bulge-DNAzyme complex. PLoS One (2011) 0.75
Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science (1991) 12.17
PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature (1993) 8.83
Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA. Proc Natl Acad Sci U S A (2006) 3.40
Solid-phase synthesis of peptide nucleic acids. J Pept Sci (1997) 2.67
Stability of peptide nucleic acids in human serum and cellular extracts. Biochem Pharmacol (1994) 2.60
Peptide nucleic acid (PNA). A DNA mimic with a peptide backbone. Bioconjug Chem (1994) 2.44
Single base pair mutation analysis by PNA directed PCR clamping. Nucleic Acids Res (1993) 2.20
Sequence specific inhibition of DNA restriction enzyme cleavage by PNA. Nucleic Acids Res (1993) 2.15
Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA. Nucleic Acids Res (1995) 2.07
DNA-like double helix formed by peptide nucleic acid. Nature (1994) 1.87
A multi-site study using high-resolution HLA genotyping by next generation sequencing. Tissue Antigens (2011) 1.81
DNA unwinding upon strand-displacement binding of a thymine-substituted polyamide to double-stranded DNA. Proc Natl Acad Sci U S A (1993) 1.80
An introduction to peptide nucleic acid. Curr Issues Mol Biol (1999) 1.57
Sequence selective double strand DNA cleavage by peptide nucleic acid (PNA) targeting using nuclease S1. Nucleic Acids Res (1993) 1.46
Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters. Proc Natl Acad Sci U S A (1994) 1.42
Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand. Gene (1994) 1.39
Evidence for (PNA)2/DNA triplex structure upon binding of PNA to dsDNA by strand displacement. J Mol Recognit (1994) 1.36
PNA interference mapping demonstrates functional domains in the noncoding RNA Xist. Proc Natl Acad Sci U S A (2001) 1.26
Sequence-influenced interactions of oligoacridines with DNA detected by retarded gel electrophoretic migrations. Biochemistry (1988) 1.24
Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells. Proc Natl Acad Sci U S A (1998) 1.21
Peptide nucleic acids and their potential applications in biotechnology. Trends Biotechnol (1993) 1.10
Enhanced PCR amplification of VNTR locus D1S80 using peptide nucleic acid (PNA). Nucleic Acids Res (1995) 1.09
Site specificity of psoralen-DNA interstrand cross-linking determined by nuclease Bal31 digestion. Biochemistry (1986) 1.08
Coat protein regulates formation of replication complexes during tobacco mosaic virus infection. Proc Natl Acad Sci U S A (2004) 1.07
Uranyl salts as photochemical agents for cleavage of DNA and probing of protein-DNA contacts. FEBS Lett (1988) 1.04
Biochemical evidence that a D-loop is part of a four-stranded PNA-DNA bundle. Nickel-mediated cleavage of duplex DNA by a Gly-Gly-His bis-PNA. Biochemistry (1996) 1.03
An easy method using glutaraldehyde-introduced fluorescence for the microscopic analysis of plant biotrophic interactions. J Microsc (2008) 1.01
Interactions of DNA binding ligands with PNA-DNA hybrids. Nucleic Acids Res (1994) 0.98
Single base discrimination of CENP-B repeats on mouse and human Chromosomes with PNA-FISH. Mamm Genome (1999) 0.98
Structural characterization of PNA-DNA duplexes by NMR. Evidence for DNA in a B-like conformation. Biochemistry (1994) 0.98
Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors. Cold Spring Harb Symp Quant Biol (2005) 0.95
Peptide nucleic acid (PNA): a model structure for the primordial genetic material? Orig Life Evol Biosph (1993) 0.94
Peptide nucleic acid pre-gel hybridization: an alternative to southern hybridization. Proc Natl Acad Sci U S A (1996) 0.93
Uranyl photofootprinting of triple helical DNA. Nucleic Acids Res (1992) 0.92
Acridine-psoralen amines and their interaction with deoxyribonucleic acid. Biochemistry (1983) 0.92
In vivo hybridization of technetium-99m-labeled peptide nucleic acid (PNA). J Nucl Med (1997) 0.89
Affinity purification of DNA and RNA from environmental samples with peptide nucleic acid clamps. Appl Environ Microbiol (2000) 0.88
Sensitive quantitation of endotoxin by enzyme-linked immunosorbent assay with monoclonal antibody against Limulus peptide C. J Clin Microbiol (1994) 0.87
Psoralenamines. 3. Synthesis, pharmacological behavior, and DNA binding of 5-(aminomethyl)-8-methoxy-, 5-[[(3-aminopropyl)oxy]methyl]-, and 8-[(3-aminopropyl)oxy]psoralen derivatives. J Med Chem (1985) 0.86
Photocleavage of DNA and photofootprinting of E. coli RNA polymerase bound to promoter DNA by azido-9-acridinylamines. Nucleic Acids Res (1988) 0.86
Sequence-selective DNA recognition by synthetic ligands. Bioconjug Chem (1991) 0.86
Aggregation of TMV CP plays a role in CP functions and in coat-protein-mediated resistance. Virology (2007) 0.85
Adenosine-guanosine preferential photocleavage of DNA by azido-benzoyl- and diazocyclopenta-dienylcarbonyloxy derivatives of 9-aminoacridine. Nucleic Acids Res (1988) 0.84
Evidence of a myoepithelial cell in tick salivary glands. Int J Parasitol (1994) 0.83
Protein crosslinking reagents containing a selenoethylene linker are cleaved by mild oxidation. Anal Biochem (1986) 0.83
Photochemistry of quinolylmethylisothioronium salts. Guanine selective DNA photocleavage reagents. Photochem Photobiol (1991) 0.83
Trace elements intake in the Faroe Islands. III. Element concentrations in human organs in populations from Bergen (Norway) and the Faroe Islands. Sci Total Environ (1989) 0.83
Unique chromosome identification and sequence-specific structural analysis with short PNA oligomers. Mamm Genome (2000) 0.82
Differential blocking of coagulation-activating pathways of Limulus amebocyte lysate. J Clin Microbiol (1994) 0.81
New compounds related to podophyllotoxin and congeners: synthesis, structure elucidation and biological testing. Acta Chem Scand (1993) 0.81
9-acridinyl and 2-methoxy-6-chloro-9-acridinyl derivatives of aliphatic di-, tri-, and tetraamines. Chemistry, cytostatic activity, and schistosomicidal activity. J Med Chem (1983) 0.80
The oxidative cleavability of protein cross-linking reagents containing organoselenium bridges. Bioconjug Chem (1991) 0.80
Molecular imprinting approach for the recognition of adenine in aqueous medium and hydrolysis of adenosine 5'-triphosphate. Bioconjug Chem (1996) 0.80
Strand displacement recognition of mixed adenine-cytosine sequences in double stranded DNA by thymine-guanine PNA (peptide nucleic acid). Bioorg Med Chem (2001) 0.79
Photochemical crosslinking of protein and DNA in chromatin. II. Synthesis and application of psoralen-cystamine-arylazido photocrosslinking reagents. Anal Biochem (1985) 0.78
Sequence/structure selective thermal and photochemical cleavage of yeast-tRNA(Phe) by UO(2)2+. J Mol Recognit (1997) 0.78
Photochemical cleavage of DNA by nitrobenzamides linked to 9-aminoacridine. Biochemistry (1988) 0.78
Murine T cell responses to melittin and its analogs. J Immunol (1991) 0.78
Telomeres in the haemopoietic system. Ciba Found Symp (1997) 0.78
Monoclonal antibodies to thioguanine: influence of coupling position on fine specificity. Bioconjug Chem (1994) 0.78
Photochemical cis-trans isomerization of furylacryloylpeptides and their different kinetic behavior as substrates for carboxypeptidase Y. Anal Biochem (1991) 0.78
Affinity therapeutics. 1. Selective incorporation of 2-thiouracil derivatives in murine melanomas. Cytostatic activity of 2-thiouracil arotinoids, 2-thiouracil retinoids, arotinoids, and retinoids. J Med Chem (1982) 0.77
On the DNA bending by psoralen interstrand crosslinking. A gel electrophoretic study. Photochem Photobiol (1988) 0.77
Thermal chemistry of podophyllotoxin in ethanol and a comparison of the cytostatic activity of the thermolysis products. J Pharm Sci (1986) 0.77
9-Acridinylpeptides and 9-acridinyl-4-nitrophenylsulfonylpeptides. Synthesis, binding to DNA, and photoinduced DNA cleavage. Int J Pept Protein Res (1988) 0.76
Effect of antitumor diarylsulfonylureas on in vivo and in vitro mitochondrial structure and functions. Cancer Res (1991) 0.75
Gastric cancer incidence in the Faroe Islands. Br J Cancer (1984) 0.75
Spectrometry senses more than a small difference. Nat Biotechnol (1997) 0.75
[Cancer registration in the Faeroe Islands]. Ugeskr Laeger (1998) 0.75
The structure and total synthesis of cassaic acid. J Am Chem Soc (1966) 0.75
Peptide amidation by enzymatic transacylation and photolysis. Int J Pept Protein Res (1993) 0.75
Pitfalls in characterization of protein interactions using radioiodinated crosslinking reagents. Preparation and testing of a novel photochemical 125I-label transfer reagent. Bioconjug Chem (1994) 0.75
Application of quantitative structure-activity relationship modeling to the evaluation of the changes in enzymatic activity of carboxypeptidase Y upon chemical modifications. Arch Biochem Biophys (1993) 0.75
C-terminal amidation of calcitonin by carboxypeptidase Y catalyzed transpeptidation with a photocleavable nucleophile. Pept Res (1993) 0.75