Published in Protein Sci on October 01, 1995
Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein. Protein Sci (2002) 1.35
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Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains. Nature (1994) 2.29
The solution structure of human epidermal growth factor. Nature (1987) 1.94
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Solution structure of murine epidermal growth factor: determination of the polypeptide backbone chain-fold by nuclear magnetic resonance and distance geometry. Proc Natl Acad Sci U S A (1987) 1.24
The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity. J Biol Chem (1992) 1.21
A 10-kDa cyanogen bromide fragment from the epidermal growth factor homology domain of rabbit thrombomodulin contains the primary thrombin binding site. J Biol Chem (1988) 1.19
The last three consecutive epidermal growth factor-like structures of human thrombomodulin comprise the minimum functional domain for protein C-activating cofactor activity and anticoagulant activity. J Biol Chem (1989) 1.13
Microthrombomodulin. Residues 310-486 from the epidermal growth factor precursor homology domain of thrombomodulin will accelerate protein C activation. J Biol Chem (1989) 1.11
Further localization of binding sites for thrombin and protein C in human thrombomodulin. J Biol Chem (1990) 1.09
The solution structure of human transforming growth factor alpha. Eur J Biochem (1991) 0.99
Functional domains of membrane-bound human thrombomodulin. EGF-like domains four to six and the serine/threonine-rich domain are required for cofactor activity. J Biol Chem (1992) 0.97
Disulphide bridges of bovine factor X. Biochem J (1987) 0.97
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Proteolytic formation and properties of functional domains of thrombomodulin. J Biol Chem (1987) 0.93
Thrombin-bound structure of an EGF subdomain from human thrombomodulin determined by transferred nuclear Overhauser effects. Biochemistry (1994) 0.93
Solution structure of human type-alpha transforming growth factor determined by heteronuclear NMR spectroscopy and refined by energy minimization with restraints. Biochemistry (1993) 0.92
Proton nuclear magnetic resonance study on the solution conformation of human epidermal growth factor. Proc Natl Acad Sci U S A (1987) 0.90
Measurement of amide hydrogen exchange by MALDI-TOF mass spectrometry. Anal Chem (1998) 2.04
Identification of protein-protein interfaces by decreased amide proton solvent accessibility. Proc Natl Acad Sci U S A (1998) 2.02
Structural evaluation of phospholipid bicelles for solution-state studies of membrane-associated biomolecules. Biophys J (2001) 1.83
Solvent accessibility of the thrombin-thrombomodulin interface. J Mol Biol (2001) 1.58
Phosphorylation causes subtle changes in solvent accessibility at the interdomain interface of methylesterase CheB. J Mol Biol (2001) 1.22
Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution. Biochemistry (1994) 1.21
Electrostatic dependence of the thrombin-thrombomodulin interaction. J Mol Biol (2000) 1.20
Triosephosphate isomerase requires a positively charged active site: the role of lysine-12. Biochemistry (1994) 1.19
Orientation and effects of mastoparan X on phospholipid bicelles. Biophys J (2001) 1.11
Crystal structure of the K12M/G15A triosephosphate isomerase double mutant and electrostatic analysis of the active site. Biochemistry (1994) 1.04
Large-scale expression, purification and characterization of small fragments of thrombomodulin: the roles of the sixth domain and of methionine 388. Protein Eng (1995) 1.04
Branchpoint for heme alkylation and metabolite formation in the oxidation of arylacetylenes by cytochrome P-450. J Biol Chem (1985) 1.04
2H NMR studies of a myristoylated peptide in neutral and acidic phospholipid bicelles. Biochemistry (1998) 1.03
Energetics of thrombin-thrombomodulin interaction. Biochemistry (1997) 1.00
Production of large quantities of isotopically labeled protein in Pichia pastoris by fermentation. J Biomol NMR (1999) 0.98
Conformational dimorphism and transmembrane orientation of prion protein residues 110-136 in bicelles. Biochemistry (2001) 0.94
Killing and mutation of human lymphoblast cells by aflatoxin B1: evidence for an inducible repair response. Cancer Res (1987) 0.94
Thrombin-bound structure of an EGF subdomain from human thrombomodulin determined by transferred nuclear Overhauser effects. Biochemistry (1994) 0.93
Crystal structure of the mutant yeast triosephosphate isomerase in which the catalytic base glutamic acid 165 is changed to aspartic acid. Biochemistry (1994) 0.92
Mechanism of oxidation of pi bonds by cytochrome P-450. Electronic requirements of the transition state in the turnover of phenylacetylenes. J Biol Chem (1987) 0.92
Preparation of insoluble transmembrane peptides: glycophorin-A, prion (110-137), and FGFR (368-397). Anal Biochem (1999) 0.91
Thrombin inhibition by cyclic peptides from thrombomodulin. Protein Sci (1995) 0.89
Structural resiliency of an EGF-like subdomain bound to its target protein, thrombin. Protein Sci (1996) 0.88
Deprotection of S-acetamidomethyl cysteine-containing peptides by silver trifluoromethanesulfonate avoids the oxidation of methionines. Anal Biochem (1995) 0.88
Disulfide bond plasticity in epidermal growth factor. Proteins (2000) 0.87
The role of water in the catalytic efficiency of triosephosphate isomerase. Biochemistry (1999) 0.85
Solution structure of the smallest cofactor-active fragment of thrombomodulin. Nat Struct Biol (2000) 0.85
Mutation of human lymphoblasts exposed to low concentrations of chemical mutagens for long periods of time. Mutat Res (1983) 0.84
Expression of highly disulfide-bonded proteins in Pichia pastoris. Structure (1994) 0.84
Mutation of xeroderma pigmentosum lymphoblasts by far-ultraviolet light. Mutat Res (1984) 0.84
Synthesis, activity, and preliminary structure of the fourth EGF-like domain of thrombomodulin. Protein Sci (1995) 0.83
Generation of protease-deficient strains and their use in heterologous protein expression. Methods Mol Biol (1998) 0.81
Mechanism of thrombin clearance by human astrocytoma cells. J Neurochem (1999) 0.79
The fifth epidermal growth factor-like domain of thrombomodulin does not have an epidermal growth factor-like disulfide bonding pattern. Proc Natl Acad Sci U S A (1996) 0.76
cDNA sequence of rabbit tissue factor pathway inhibitor. Nucleic Acids Res (1992) 0.75
Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern. J Mol Biol (1997) 0.75