Published in Am J Physiol on December 01, 1995
Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection. Am J Pathol (2003) 4.67
In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice. Mol Med (2006) 1.25
Pancreatic duct ligation reduces lung injury following trauma and hemorrhagic shock. Ann Surg (2004) 0.97
Intoxication by intraperitoneal injection or oral gavage equally potentiates postburn organ damage and inflammation. Mediators Inflamm (2013) 0.91
Alcohol, burn injury, and the intestine. J Emerg Trauma Shock (2008) 0.87
Mechanism of Liver Injury during Obstructive Jaundice: Role of Nitric Oxide, Splenic Cytokines, and Intestinal Flora. J Clin Biochem Nutr (2007) 0.84
An alteration of the gut-liver axis drives pulmonary inflammation after intoxication and burn injury in mice. Am J Physiol Gastrointest Liver Physiol (2014) 0.83
The role of tumour necrosis factor-alpha in renal dysfunction following mild haemorrhage in rats. Int J Exp Pathol (2004) 0.79
Recombinant factor XIII mitigates hemorrhagic shock-induced organ dysfunction. J Surg Res (2010) 0.78
Intestinal colonization with Enterococcus faecium does not influence pulmonary defense against Pseudomonas aeruginosa in mice. PLoS One (2009) 0.75
Alteration of Esophageal Microbiome by Antibiotic Treatment Does Not Affect Incidence of Rat Esophageal Adenocarcinoma. Dig Dis Sci (2016) 0.75
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. Proc Natl Acad Sci U S A (1993) 9.47
Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices. Nat Biotechnol (1999) 5.13
Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature (1993) 4.81
Transforming growth factor-beta 3 is required for secondary palate fusion. Nat Genet (1995) 4.46
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA. EMBO J (2001) 4.36
Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1. Nature (2000) 4.12
Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models. J Natl Cancer Inst (2000) 4.09
The importance of patient preference in the decision to screen for prostate cancer. Prostate Patient Outcomes Research Team. J Gen Intern Med (1996) 3.87
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance. J Mol Biol (1994) 3.85
Magnetic order close to superconductivity in the iron-based layered LaO1-xFxFeAs systems. Nature (2008) 3.37
Effect of resynchronization therapy stimulation site on the systolic function of heart failure patients. Circulation (2001) 3.25
Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state. Proc Natl Acad Sci U S A (2000) 3.13
Disruption of alpha3 connexin gene leads to proteolysis and cataractogenesis in mice. Cell (1997) 3.10
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids. Proc Natl Acad Sci U S A (1999) 3.03
Structural and magnetic phase diagram of CeFeAsO(1- x)F(x) and its relation to high-temperature superconductivity. Nat Mater (2008) 2.83
Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J Biol Chem (1993) 2.81
Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region. Oncogene (2010) 2.73
Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms. Structure (1996) 2.69
Relation of alleles of the collagen type Ialpha1 gene to bone density and the risk of osteoporotic fractures in postmenopausal women. N Engl J Med (1998) 2.64
Role of the gut in multiple organ failure: bacterial translocation and permeability changes. World J Surg (1996) 2.63
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not. Proc Natl Acad Sci U S A (1994) 2.56
Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J (2000) 2.53
Structure of HIV-1 reverse transcriptase/DNA complex at 7 A resolution showing active site locations. Nature (1992) 2.52
Post-hemorrhagic shock mesenteric lymph is cytotoxic to endothelial cells and activates neutrophils. Shock (1998) 2.48
The gut as a portal of entry for bacteremia. Role of protein malnutrition. Ann Surg (1987) 2.38
Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. Proc Natl Acad Sci U S A (2000) 2.30
Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock. Ann Surg (1998) 2.24
Impact of complex genetic variation in COMT on human brain function. Mol Psychiatry (2006) 2.22
Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function. Proc Natl Acad Sci U S A (1999) 2.18
Hypertrophic burn scars: analysis of variables. J Trauma (1983) 2.15
Tunable (deltapi, deltapi)-type antiferromagnetic order in alpha-Fe(Te,Se) superconductors. Phys Rev Lett (2009) 2.03
Ultrahigh resolution optical coherence tomography of Barrett's esophagus: preliminary descriptive clinical study correlating images with histology. Endoscopy (2007) 2.00
Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase. Biochemistry (1995) 1.93
Three-dimensional optical coherence tomography of Barrett's esophagus and buried glands beneath neosquamous epithelium following radiofrequency ablation. Endoscopy (2009) 1.82
Hemorrhagic shock induces bacterial translocation from the gut. J Trauma (1988) 1.77
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes Dev (1999) 1.74
Comparison of translocation rates of various indigenous bacteria from the gastrointestinal tract to the mesenteric lymph node. J Infect Dis (1988) 1.73
VEGF induces NO-dependent hyperpermeability in coronary venules. Am J Physiol (1996) 1.70
Endotoxin promotes the translocation of bacteria from the gut. Arch Surg (1987) 1.68
A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway. J Biol Chem (2000) 1.67
Paired box 6 (PAX6) regulates glucose metabolism via proinsulin processing mediated by prohormone convertase 1/3 (PC1/3). Diabetologia (2008) 1.66
Emergent excitations in a geometrically frustrated magnet. Nature (2002) 1.66
Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant. J Mol Biol (1996) 1.65
Conditional lineage ablation to model human diseases. Proc Natl Acad Sci U S A (1998) 1.64
Effect of oral antibiotics and bacterial overgrowth on the translocation of the GI tract microflora in burned rats. J Trauma (1985) 1.61
Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer. Cell Mol Life Sci (2003) 1.60
Inosine improves gut permeability and vascular reactivity in endotoxic shock. Crit Care Med (2001) 1.57
Targeted expression of a dominant-negative K(v)4.2 K(+) channel subunit in the mouse heart. Circ Res (1999) 1.56
Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site. Chem Biol (1999) 1.56
zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathway. Cell Death Differ (2010) 1.54
A large-scale population-based study of the association of vitamin D receptor gene polymorphisms with bone mineral density. J Bone Miner Res (1996) 1.54
Role of C5a in multiorgan failure during sepsis. J Immunol (2001) 1.53
Electronic phase separation at the LaAlO₃/SrTiO₃ interface. Nat Commun (2011) 1.51
T lymphocytes in host defense against bacterial translocation from the gastrointestinal tract. Infect Immun (1994) 1.51
The role of expectations in patients' reports of post-operative outcomes and improvement following therapy. Med Care (1993) 1.50
Bacterial translocation from the gastrointestinal tracts of rats receiving thermal injury. Infect Immun (1984) 1.43
Chronic idiopathic intestinal pseudo-obstruction. A surgical approach. Ann Surg (1980) 1.42
Intestinal cytokine response after gut ischemia: role of gut barrier failure. Ann Surg (1999) 1.42
Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep. Neuroscience (2003) 1.41
Priming of neutrophil [Ca2+]i signaling and oxidative burst by human fracture fluids. J Trauma (1999) 1.40
Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother (1994) 1.40
Anisotropy and corotation of galactic cosmic rays. Science (2006) 1.39
A modified method of labia minora reduction: the de-epithelialised reduction of the central and posterior labia minora. J Plast Reconstr Aesthet Surg (2012) 1.38
MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. Cell Death Differ (2011) 1.33
Superconductivity in the non-oxide perovskite MgCNi3. Nature (2001) 1.32
The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance. J Mol Biol (2001) 1.29
PAF-mediated Ca2+ influx in human neutrophils occurs via store-operated mechanisms. J Leukoc Biol (2001) 1.28
A concentration-dependent mechanism by which serum albumin inactivates replacement lung surfactants. Biophys J (2002) 1.28
Gut-derived mesenteric lymph: a link between burn and lung injury. Arch Surg (1999) 1.28
Immunosuppression and intestinal bacterial overgrowth synergistically promote bacterial translocation. Arch Surg (1988) 1.27
Large exchange bias after zero-field cooling from an unmagnetized state. Phys Rev Lett (2011) 1.26
Msx1 antagonizes the myogenic activity of Pax3 in migrating limb muscle precursors. Development (1999) 1.26
The incidence of recurrent penetrating trauma in an urban trauma center. J Trauma (1991) 1.26
Room-temperature ferromagnetism in carbon-doped ZnO. Phys Rev Lett (2007) 1.26
Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance. J Mol Biol (1998) 1.25
Targeting of VEGF-mediated angiogenesis to rat myocardium using ultrasonic destruction of microbubbles. Gene Ther (2005) 1.25
The gut: a cytokine-generating organ in systemic inflammation? Shock (1995) 1.25
Ferroelectricity in an ising chain magnet. Phys Rev Lett (2008) 1.25
Enhanced expression of Duffy antigen receptor for chemokines by breast cancer cells attenuates growth and metastasis potential. Oncogene (2006) 1.24
The association between weight history and physical performance in the Health, Aging and Body Composition study. Int J Obes (Lond) (2007) 1.24
Genomic biomarkers and cellular pathways of ischemic stroke by RNA gene expression profiling. Neurology (2010) 1.23
Absence of intestinal bile promotes bacterial translocation. Am Surg (1992) 1.23
Apoptosis in endometrial glandular and stromal cells in women with and without endometriosis. Hum Reprod (2001) 1.23
Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple myeloma: downregulation of NF-kappa B induces apoptosis. Br J Haematol (2001) 1.22
Charge, orbital and spin ordering phenomena in the mixed valence manganite (NaMn3+(3))(Mn3+(2)Mn4+(2))O12. Nat Mater (2003) 1.22
Exposure to breast milk in infancy and adult breast cancer risk. J Natl Cancer Inst (1998) 1.22
Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras. J Biol Chem (2000) 1.21
Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species. J Biol Chem (2000) 1.20
Allogeneic mesenchymal stem cell and mesenchymal stem cell-differentiated chondrocyte suppress the responses of type II collagen-reactive T cells in rheumatoid arthritis. Rheumatology (Oxford) (2008) 1.20
BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast. J Biol Chem (1998) 1.19
Ferromagnetism in dilute magnetic semiconductors through defect engineering: Li-doped ZnO. Phys Rev Lett (2010) 1.19
Myosin light chain phosphorylation: modulation of basal and agonist-stimulated venular permeability. Am J Physiol (1997) 1.19
Low molecular weight polyethylenimines linked by beta-cyclodextrin for gene transfer into the nervous system. J Gene Med (2006) 1.19
Parkin and PINK1 mutations in early-onset Parkinson's disease: comprehensive screening in publicly available cases and control. J Med Genet (2009) 1.19
Identification of disease-specific genes in chronic pancreatitis using DNA array technology. Ann Surg (2001) 1.16