Published in J Gen Physiol on October 01, 1995
Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation. J Gen Physiol (2002) 2.37
Immobilizing the moving parts of voltage-gated ion channels. J Gen Physiol (2000) 1.91
The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. Biophys J (1999) 1.85
Molecular action of lidocaine on the voltage sensors of sodium channels. J Gen Physiol (2003) 1.56
Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements. J Gen Physiol (2004) 1.55
Voltage-sensor mutations in channelopathies of skeletal muscle. J Physiol (2010) 1.43
Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels. J Physiol (2007) 1.43
Movement of voltage sensor S4 in domain 4 is tightly coupled to sodium channel fast inactivation and gating charge immobilization. J Gen Physiol (1999) 1.37
The role of the putative inactivation lid in sodium channel gating current immobilization. J Gen Physiol (2000) 1.25
A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels. J Gen Physiol (2000) 1.21
Sodium channel molecular conformations and antiarrhythmic drug affinity. Trends Cardiovasc Med (2010) 1.20
Local anesthetics disrupt energetic coupling between the voltage-sensing segments of a sodium channel. J Gen Physiol (2008) 1.18
Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels. J Gen Physiol (2008) 1.17
beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel. J Gen Physiol (2007) 1.16
Gating of skeletal and cardiac muscle sodium channels in mammalian cells. J Physiol (1999) 1.16
Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation. Biophys J (1999) 1.15
Neurotoxins and their binding areas on voltage-gated sodium channels. Front Pharmacol (2011) 1.15
Independent versus coupled inactivation in sodium channels. Role of the domain 2 S4 segment. J Gen Physiol (1998) 1.14
Molecular analysis of potential hinge residues in the inactivation gate of brain type IIA Na+ channels. J Gen Physiol (1997) 1.07
The hitchhiker's guide to the voltage-gated sodium channel galaxy. J Gen Physiol (2016) 1.03
Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of persistent currents. J Gen Physiol (1999) 1.02
Site-3 toxins and cardiac sodium channels. Toxicon (2006) 0.99
Inwardly permeating Na ions generate the voltage dependence of resurgent Na current in cerebellar Purkinje neurons. J Neurosci (2010) 0.94
Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation. J Physiol (2004) 0.92
Voltage-dependent displacement of the scorpion toxin Ts3 from sodium channels and its implication on the control of inactivation. Br J Pharmacol (2004) 0.90
Modulation of neuronal sodium channels by the sea anemone peptide BDS-I. J Neurophysiol (2012) 0.88
Voltage-gated sodium channels in the mammalian heart. Glob Cardiol Sci Pract (2014) 0.85
Ion channel associated diseases: overview of molecular mechanisms. Chem Rev (2012) 0.82
Open- and closed-state fast inactivation in sodium channels: differential effects of a site-3 anemone toxin. Channels (Austin) (2011) 0.80
Electrotonic suppression of early afterdepolarizations in the neonatal rat ventricular myocyte monolayer. J Physiol (2013) 0.80
The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels. Biophys J (2002) 0.79
Voltage gating by molecular subunits of Na+ and K+ ion channels: higher-dimensional cubic kinetics, rate constants, and temperature. J Neurophysiol (2015) 0.79
Differential effects of Zn2+ on activation, deactivation, and inactivation kinetics in neuronal voltage-gated Na+ channels. Pflugers Arch (2011) 0.77
Extracellular protons inhibit charge immobilization in the cardiac voltage-gated sodium channel. Biophys J (2013) 0.75
Retracted A gating model for wildtype and R1448H Nav1.4 channels in paramyotonia. Acta Myol (2014) 0.75
Direct evidence that scorpion α-toxins (site-3) modulate sodium channel inactivation by hindrance of voltage-sensor movements. PLoS One (2013) 0.75
Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels. Biophys J (2015) 0.75
Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels. Neuroscience (2014) 0.75
Gating properties of a sodium channel with three arginines substituted by histidines in the central part of voltage sensor S4D4. J Membr Biol (2003) 0.75
Structure and function of voltage-dependent sodium channels: comparison of brain II and cardiac isoforms. Physiol Rev (1996) 2.01
The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4. Biophys J (1999) 1.85
Nonlinear relation between Vmax and INa in canine cardiac Purkinje cells. Circ Res (1988) 1.78
Mibefradil block of cloned T-type calcium channels. J Pharmacol Exp Ther (2000) 1.52
Sodium current in voltage clamped internally perfused canine cardiac Purkinje cells. Biophys J (1987) 1.47
Kinetic analysis of single sodium channels from canine cardiac Purkinje cells. J Gen Physiol (1990) 1.44
Mechanism of cAMP-dependent modulation of cardiac sodium channel current kinetics. Circ Res (1993) 1.38
Open sodium channel properties of single canine cardiac Purkinje cells. Biophys J (1987) 1.30
Is there a second external lidocaine binding site on mammalian cardiac cells? Am J Physiol (1989) 1.29
The role of the putative inactivation lid in sodium channel gating current immobilization. J Gen Physiol (2000) 1.25
Mechanisms of extracellular divalent and trivalent cation block of the sodium current in canine cardiac Purkinje cells. J Physiol (1992) 1.21
A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B. J Biol Chem (1998) 1.20
Gating of skeletal and cardiac muscle sodium channels in mammalian cells. J Physiol (1999) 1.16
Optimization of a mammalian expression system for the measurement of sodium channel gating currents. Am J Physiol (1996) 1.07
A structural motif for the voltage-gated potassium channel pore. Proc Natl Acad Sci U S A (1995) 1.02
Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of persistent currents. J Gen Physiol (1999) 1.02
Nonequilibrium response spectroscopy of voltage-sensitive ion channel gating. Biophys J (1998) 1.02
Dose-dependent modulation of the cardiac sodium channel by sea anemone toxin ATXII. Circ Res (1992) 0.99
Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination. Biochemistry (1995) 0.96
Two components of use-dependent block of sodium current by lidocaine in voltage clamped cardiac Purkinje cells. J Mol Cell Cardiol (1991) 0.96
Sodium channels in cardiac Purkinje cells. Experientia (1987) 0.95
Differences in the binding sites of two site-3 sodium channel toxins. Pflugers Arch (1997) 0.95
Isoform-dependent interaction of voltage-gated sodium channels with protons. J Physiol (2006) 0.90
Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel. J Biol Chem (1996) 0.84
Point mutations in domain III of a Drosophila neuronal Na channel confer resistance to allethrin. Insect Biochem Mol Biol (2000) 0.84
Modification of sodium channel inactivation by alpha-chymotrypsin in canine cardiac Purkinje cells. J Cardiovasc Electrophysiol (1993) 0.84
The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B. J Biol Chem (1996) 0.83
Effects of physiological beating on the contractility of cat ventricular muscle. Am J Physiol (1985) 0.81
Cardiac sodium channels expressed in a peripheral neurotumor-derived cell line, RT4-B8. Am J Physiol (1996) 0.79
The Anrep effect: an intrinsic myocardial mechanism. Can J Physiol Pharmacol (1988) 0.79
Effect of external Ca2+ concentration on stretch-augmented natriuretic peptide secretion by rat atria. Am J Physiol (1991) 0.78
A direct effect of forskolin on sodium channel bursting. Pflugers Arch (1995) 0.78
Use-dependent block of sodium current by ethmozin in voltage-clamped internally perfused canine cardiac Purkinje cells. J Mol Cell Cardiol (1988) 0.77
Endocytosis and uptake of lucifer yellow by cultured atrial myocytes and isolated intact atria from adult rats. Regulation and subcellular localization. Circ Res (1994) 0.76
Atrionatriuretic peptide and calcium-conducting sodium channels. Science (1991) 0.76
Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel. Biochemistry (1996) 0.75
Fluid-phase endocytosis by in situ cardiac myocytes of rat atria. Am J Physiol (1993) 0.75
Effects of inotropic interventions on end systolic length-force curve of cat ventricular muscle. Cardiovasc Res (1987) 0.75
Sodium currents in single cardiac Purkinje cells. J Am Coll Cardiol (1986) 0.75
Inhibition of atrial peptide secretion at different stages of the secretory process: Ca2+ dependence. Am J Physiol (1991) 0.75