1
|
RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids.
|
RNA
|
1999
|
3.28
|
2
|
Automatic determination of protein backbone resonance assignments from triple resonance nuclear magnetic resonance data.
|
Methods Enzymol
|
2001
|
3.09
|
3
|
Automated analysis of protein NMR assignments using methods from artificial intelligence.
|
J Mol Biol
|
1997
|
2.86
|
4
|
Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein.
|
Nat Struct Biol
|
1997
|
2.41
|
5
|
High-level production of uniformly ¹⁵N- and ¹³C-enriched fusion proteins in Escherichia coli.
|
J Biomol NMR
|
1996
|
2.38
|
6
|
Solution NMR structure of the major cold shock protein (CspA) from Escherichia coli: identification of a binding epitope for DNA.
|
Proc Natl Acad Sci U S A
|
1994
|
2.20
|
7
|
A novel RNA-binding motif in influenza A virus non-structural protein 1.
|
Nat Struct Biol
|
1997
|
2.16
|
8
|
Partial NMR assignments for uniformly (13C, 15N)-enriched BPTI in the solid state.
|
J Biomol NMR
|
2000
|
1.62
|
9
|
An amino-terminal polypeptide fragment of the influenza virus NS1 protein possesses specific RNA-binding activity and largely helical backbone structure.
|
RNA
|
1995
|
1.59
|
10
|
Automated analysis of NMR assignments and structures for proteins.
|
Curr Opin Struct Biol
|
1999
|
1.57
|
11
|
SPINE: an integrated tracking database and data mining approach for identifying feasible targets in high-throughput structural proteomics.
|
Nucleic Acids Res
|
2001
|
1.52
|
12
|
High-resolution solution NMR structure of the Z domain of staphylococcal protein A.
|
J Mol Biol
|
1997
|
1.52
|
13
|
Structures of bacterial immunoglobulin-binding domains and their complexes with immunoglobulins.
|
Curr Opin Struct Biol
|
1995
|
1.37
|
14
|
Structural genomics: keystone for a Human Proteome Project.
|
Nat Struct Biol
|
1999
|
1.36
|
15
|
The structure of the N-terminus of striated muscle alpha-tropomyosin in a chimeric peptide: nuclear magnetic resonance structure and circular dichroism studies.
|
Biochemistry
|
1998
|
1.36
|
16
|
Solution NMR structure and backbone dynamics of the major cold-shock protein (CspA) from Escherichia coli: evidence for conformational dynamics in the single-stranded RNA-binding site.
|
Biochemistry
|
1998
|
1.29
|
17
|
Solution structure of murine epidermal growth factor: determination of the polypeptide backbone chain-fold by nuclear magnetic resonance and distance geometry.
|
Proc Natl Acad Sci U S A
|
1987
|
1.24
|
18
|
NMR structural analysis of an analog of an intermediate formed in the rate-determining step of one pathway in the oxidative folding of bovine pancreatic ribonuclease A: automated analysis of 1H, 13C, and 15N resonance assignments for wild-type and [C65S, C72S] mutant forms.
|
Biochemistry
|
1997
|
1.18
|
19
|
Design of a "minimAl" homeodomain: the N-terminal arm modulates DNA binding affinity and stabilizes homeodomain structure.
|
Proc Natl Acad Sci U S A
|
1994
|
1.13
|
20
|
Solution NMR structure and folding dynamics of the N terminus of a rat non-muscle alpha-tropomyosin in an engineered chimeric protein.
|
J Mol Biol
|
2001
|
1.09
|
21
|
Structural characterization of an analog of the major rate-determining disulfide folding intermediate of bovine pancreatic ribonuclease A.
|
Biochemistry
|
1997
|
1.04
|
22
|
Identification of two anti-parallel beta-sheet conformations in the solution structure of murine epidermal growth factor by proton magnetic resonance.
|
Proc Natl Acad Sci U S A
|
1986
|
1.03
|
23
|
Propagation of experimental uncertainties using the Lipari-Szabo model-free analysis of protein dynamics.
|
J Biomol NMR
|
1998
|
1.03
|
24
|
Crankshaft motions of the polypeptide backbone in molecular dynamics simulations of human type-alpha transforming growth factor.
|
J Biomol NMR
|
1995
|
1.02
|
25
|
Phase labeling of C-H and C-C spin-system topologies: application in PFG-HACANH and PFG-HACA(CO)NH triple-resonance experiments for determining backbone resonance assignments in proteins.
|
J Biomol NMR
|
1996
|
0.99
|
26
|
The mechanism of binding staphylococcal protein A to immunoglobin G does not involve helix unwinding.
|
Biochemistry
|
1996
|
0.99
|
27
|
An improved strategy for determining resonance assignments for isotopically enriched proteins and its application to an engineered domain of staphylococcal protein A.
|
Biochemistry
|
1993
|
0.97
|
28
|
Structural genomics: current progress.
|
Science
|
2003
|
0.97
|
29
|
Homology modeling of an RNP domain from a human RNA-binding protein: Homology-constrained energy optimization provides a criterion for distinguishing potential sequence alignments.
|
Proteins
|
1998
|
0.96
|
30
|
Application of multiple-quantum line narrowing with simultaneous 1H and 13C constant-time scalar-coupling evolution in PFG-HACANH and PFG-HACA(CO)NH triple-resonance experiments.
|
J Biomol NMR
|
1997
|
0.92
|
31
|
Combined use of 13C chemical shift and 1H alpha-13C alpha heteronuclear NOE data in monitoring a protein NMR structure refinement.
|
J Biomol NMR
|
1995
|
0.92
|
32
|
Simulated annealing with restrained molecular dynamics using a flexible restraint potential: theory and evaluation with simulated NMR constraints.
|
Protein Sci
|
1996
|
0.92
|
33
|
Solution structure of human type-alpha transforming growth factor determined by heteronuclear NMR spectroscopy and refined by energy minimization with restraints.
|
Biochemistry
|
1993
|
0.92
|
34
|
Structure-function studies of murine epidermal growth factor: expression and site-directed mutagenesis of epidermal growth factor gene.
|
Biochemistry
|
1988
|
0.91
|
35
|
Simulated annealing with restrained molecular dynamics using CONGEN: energy refinement of the NMR solution structures of epidermal and type-alpha transforming growth factors.
|
Protein Sci
|
1996
|
0.89
|
36
|
Homology modeling using simulated annealing of restrained molecular dynamics and conformational search calculations with CONGEN: application in predicting the three-dimensional structure of murine homeodomain Msx-1.
|
Protein Sci
|
1997
|
0.88
|
37
|
Human epidermal growth factor. Distinct roles of tyrosine 37 and arginine 41 in receptor binding as determined by site-directed mutagenesis and nuclear magnetic resonance spectroscopy.
|
FEBS Lett
|
1990
|
0.85
|
38
|
Estimation of dynamic parameters from NMR relaxation data using the Lipari-Szabo model-free approach and Bayesian statistical methods.
|
J Magn Reson
|
1999
|
0.85
|
39
|
Phase labeling of C-H and C-C spin-system topologies: application in constant-time PFG-CBCA(CO)NH experiments for discriminating amino acid spin-system types.
|
J Biomol NMR
|
1996
|
0.85
|
40
|
Automated sequencing of amino acid spin systems in proteins using multidimensional HCC(CO)NH-TOCSY spectroscopy and constraint propagation methods from artificial intelligence.
|
J Biomol NMR
|
1994
|
0.84
|
41
|
Human type-alpha transforming growth factor undergoes slow conformational exchange between multiple backbone conformations as characterized by nitrogen-15 relaxation measurements.
|
Biochemistry
|
1995
|
0.83
|
42
|
Conformational characterization of a single-site mutant of murine epidermal growth factor (EGF) by 1H NMR provides evidence that leucine-47 is involved in the interactions with the EGF receptor.
|
Proc Natl Acad Sci U S A
|
1989
|
0.82
|
43
|
Solution NMR evidence for a cis Tyr-Ala peptide group in the structure of [Pro93Ala] bovine pancreatic ribonuclease A.
|
Protein Sci
|
2000
|
0.81
|
44
|
The role of asparagine-32 in forming the receptor-binding epitope of human epidermal growth factor.
|
Protein Eng
|
1993
|
0.81
|
45
|
Modification of a receptor-binding surface of epidermal growth factor (EGF): analogs with enhanced receptor affinity at low pH or at neutrality.
|
Protein Eng
|
1998
|
0.81
|
46
|
Overcoming solvent saturation-transfer artifacts in protein NMR at neutral pH. Application of pulsed field gradients in measurements of 1H-15N Overhauser effects.
|
J Magn Reson B
|
1994
|
0.81
|
47
|
Equilibrium ratios of cis- and trans-proline conformers in fragments of ribonuclease A from nuclear magnetic resonance spectra of adjacent tyrosine ring resonances.
|
Biochemistry
|
1982
|
0.80
|
48
|
Efficient translation of mRNAs in influenza A virus-infected cells is independent of the viral 5' untranslated region.
|
Virology
|
2001
|
0.80
|
49
|
Local structure involving histidine-12 in reduced S-sulfonated ribonuclease A detected by proton NMR spectroscopy under folding conditions.
|
Proc Natl Acad Sci U S A
|
1984
|
0.80
|
50
|
A Bayesian statistical method for the detection and quantification of rotational diffusion anisotropy from NMR relaxation data.
|
J Magn Reson
|
2000
|
0.80
|
51
|
HYPER: a hierarchical algorithm for automatic determination of protein dihedral-angle constraints and stereospecific C beta H2 resonance assignments from NMR data.
|
J Biomol NMR
|
1999
|
0.79
|
52
|
Classification of amino acid spin systems using PFG HCC(CO)NH-TOCSY with constant-time aliphatic 13C frequency labeling.
|
J Biomol NMR
|
1995
|
0.78
|
53
|
Physical and chemical characterization of the major lactose-blockable lectin activity from fetal calf skeletal muscle.
|
Biochim Biophys Acta
|
1981
|
0.78
|
54
|
Comparison of local and global stability of an analogue of a disulfide-folding intermediate with those of the wild-type protein in bovine pancreatic ribonuclease A: identification of specific regions of stable structure along the oxidative folding pathway.
|
Biochemistry
|
1999
|
0.78
|
55
|
Lipari-Szabo mapping: A graphical approach to Lipari-Szabo analysis of NMR relaxation data using reduced spectral density mapping.
|
J Biomol NMR
|
2000
|
0.78
|
56
|
Resonance assignments for cold-shock protein ribosome-binding factor A (RbfA) from Escherichia coli.
|
J Biomol NMR
|
2001
|
0.77
|
57
|
Protein structural domain parsing by consensus reasoning over multiple knowledge sources and methods.
|
Stud Health Technol Inform
|
2001
|
0.77
|
58
|
A constraint reasoning system for automating sequence-specific resonance assignments from multidimensional protein NMR spectra.
|
Proc Int Conf Intell Syst Mol Biol
|
1993
|
0.76
|
59
|
Conformational properties of trans Ac-Asn-Pro-Tyr-NHMe and trans Ac-Tyr-Pro-Asn-NHMe in dimethylsulfoxide and in water determined by multinuclear n.m.r. spectroscopy.
|
Int J Pept Protein Res
|
1986
|
0.75
|
60
|
Automated analysis of nuclear magnetic resonance assignments for proteins.
|
Curr Opin Struct Biol
|
1995
|
0.75
|
61
|
Local structure in a tryptic fragment of performic acid oxidized ribonuclease A corresponding to a proposed polypeptide chain-folding initiation site detected by tyrosine fluorescence lifetime and proton magnetic resonance measurements.
|
Biochemistry
|
1987
|
0.75
|
62
|
Resonance assignments for the N-terminal domain from human RNA-binding protein with multiple splicing (RBP-MS).
|
J Biomol NMR
|
2001
|
0.75
|
63
|
Sensitivity-enhanced sim-CT HMQC PFG-HBHA(CO)NH and PFG-CBCA(CO)NH triple-resonance experiments.
|
J Magn Reson
|
1999
|
0.75
|
64
|
X-ray crystal structure of MTH938 from Methanobacterium thermoautotrophicum at 2.2 A resolution reveals a novel tertiary protein fold.
|
Proteins
|
2001
|
0.75
|