D Beher

Author PubWeight™ 14.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity. Biochemistry 2000 2.36
2 The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I) Science 1996 2.29
3 Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease. J Biol Chem 2001 1.96
4 Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders. Mol Cell Neurosci 2004 1.62
5 The beta A4 amyloid precursor protein binding to copper. FEBS Lett 1994 1.34
6 Reactive oxygen species and Alzheimer's disease. Biochem Pharmacol 1997 1.09
7 Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-beta(42) peptide in vascular dementia. Neuropathol Appl Neurobiol 2006 1.08
8 Determination of guinea-pig cortical gamma-secretase activity ex vivo following the systemic administration of a gamma-secretase inhibitor. Neuropharmacology 2005 0.95
9 Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and gamma-secretase activity. J Neurochem 2005 0.90
10 Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines. Ann N Y Acad Sci 1996 0.78