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Rank Title Journal Year PubWeight™‹?›
1 Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells. Science 1999 7.66
2 Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection. Science 1997 5.55
3 Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation. Nat Med 1998 5.08
4 Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC). J Infect Dis 1995 4.60
5 Limited patient adherence to highly active antiretroviral therapy for HIV-1 infection in an observational cohort study. Arch Intern Med 2001 3.74
6 Failure of zidovudine prophylaxis after accidental exposure to HIV-1. N Engl J Med 1990 3.61
7 Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men. HIV affects the immune system before CD4+ T helper cell depletion occurs. J Clin Invest 1988 3.59
8 Persistent HIV antigenaemia and decline of HIV core antibodies associated with transition to AIDS. Br Med J (Clin Res Ed) 1986 3.27
9 Distinct IgG recognition patterns during progression of subclinical and clinical infection with lymphadenopathy associated virus/human T lymphotropic virus. Br Med J (Clin Res Ed) 1986 2.75
10 Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection. Proc Natl Acad Sci U S A 1998 2.39
11 Rate of HIV-1 decline following antiretroviral therapy is related to viral load at baseline and drug regimen. AIDS 1998 2.19
12 Hepatitis B and C virus co-infection and the risk for hepatotoxicity of highly active antiretroviral therapy in HIV-1 infection. AIDS 2000 2.14
13 The safety and pharmacokinetics of a reverse transcriptase inhibitor, 3TC, in patients with HIV infection: a phase I study. AIDS 1992 2.06
14 [Therapeutic options for HIV infection should lead to increased utilization of HIV tests]. Ned Tijdschr Geneeskd 1999 2.01
15 Prevalence of Campylobacter-associated diarrhea among patients infected with human immunodeficiency virus. Clin Infect Dis 1997 1.80
16 Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group. JAMA 1996 1.77
17 Increasing cerebrospinal fluid chemokine concentrations despite undetectable cerebrospinal fluid HIV RNA in HIV-1-infected patients receiving antiretroviral therapy. J Acquir Immune Defic Syndr 2000 1.68
18 Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs. AIDS 1999 1.64
19 Effects of protease inhibitors on the course of CMV retinitis in relation to CD4+ lymphocyte responses in HIV+ patients. Br J Ophthalmol 1998 1.57
20 The steady-state pharmacokinetics of nevirapine during once daily and twice daily dosing in HIV-1-infected individuals. AIDS 2000 1.56
21 Declining incidence of AIDS dementia complex after introduction of zidovudine treatment. BMJ 1989 1.39
22 [Virological evaluation of treating HIV-infected patients with (combinations of) antiretroviral drugs at the Amsterdam Academic Medical Center, 1996/'97]. Ned Tijdschr Geneeskd 1998 1.39
23 Outcome and predictors of failure of highly active antiretroviral therapy: one-year follow-up of a cohort of human immunodeficiency virus type 1-infected persons. J Infect Dis 1999 1.32
24 Decline of antibody reactivity to outer viral core protein p17 is an earlier serological marker of disease progression in human immunodeficiency virus infection than anti-p24 decline. AIDS 1987 1.32
25 Functional T cell reconstitution and human immunodeficiency virus-1-specific cell-mediated immunity during highly active antiretroviral therapy. J Infect Dis 1999 1.28
26 Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses. AIDS Res Hum Retroviruses 2001 1.22
27 Alternative multidrug regimen provides improved suppression of HIV-1 replication over triple therapy. AIDS 1998 1.21
28 A context-learning pharmacotherapy program for preclinical medical students leads to more rational drug prescribing during their clinical clerkship in internal medicine. Clin Pharmacol Ther 2008 1.21
29 Influence of follicular dendritic cells on decay of HIV during antiretroviral therapy. Proc Natl Acad Sci U S A 2000 1.20
30 Decrease of HIV-1 RNA levels in lymphoid tissue and peripheral blood during treatment with ritonavir, lamivudine and zidovudine. Ritonavir/3TC/ZDV Study Group. AIDS 1998 1.20
31 Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection. AIDS 2001 1.18
32 Quality of life in asymptomatic- and symptomatic HIV infected patients in a trial of ritonavir/saquinavir therapy. The Prometheus Study Group. AIDS 2000 1.18
33 Clinical and virological effects of high-dose recombinant interferon-alpha in disseminated AIDS-related Kaposi's sarcoma. Lancet 1988 1.17
34 Reversibility of the pathological changes in the follicular dendritic cell network with treatment of HIV-1 infection. Proc Natl Acad Sci U S A 1999 1.16
35 Cerebrospinal fluid HIV-1 RNA during treatment with ritonavir/saquinavir or ritonavir/saquinavir/stavudine. AIDS 2000 1.16
36 Immune reconstitution after 2 years of successful potent antiretroviral therapy in previously untreated human immunodeficiency virus type 1-infected adults. J Infect Dis 1999 1.13
37 QUOTE-HIV: an instrument for assessing quality of HIV care from the patients' perspective. Qual Saf Health Care 2003 1.12
38 Antigen-driven CD4+ T cell and HIV-1 dynamics: residual viral replication under highly active antiretroviral therapy. Proc Natl Acad Sci U S A 1999 1.08
39 Failure to maintain high-dose treatment regimens during long-term use of zidovudine in patients with symptomatic human immunodeficiency virus type 1 infection. Genitourin Med 1990 1.04
40 Foscarnet and penile ulceration. Lancet 1990 1.04
41 Antigen-specific T-lymphocyte proliferative responses during highly active antiretroviral therapy (HAART) of HIV-1 infection. Immunol Lett 1999 1.02
42 Long-term quality of life outcomes in three antiretroviral treatment strategies for HIV-1 infection. AIDS 2001 1.01
43 Serological and polymerase chain reaction-based analysis of aqueous humour samples in patients with AIDS and necrotizing retinitis. AIDS 1996 1.01
44 Risk factors for hepatotoxicity in HIV-1-infected patients receiving ritonavir and saquinavir with or without stavudine. Prometheus Study Group. Clin Infect Dis 2000 1.00
45 Antibody response to viral proteins U (vpu) and R (vpr) in HIV-1-infected individuals. J Acquir Immune Defic Syndr 1990 0.99
46 Pathogenesis of HIV and its implications for serodiagnosis and monitoring of antiviral therapy. J Virol Methods 1987 0.99
47 Autoimmunity against blood cells in human immunodeficiency-virus (HIV) infection. Br J Haematol 1987 0.99
48 Echocardiographic dimensions and maximal oxygen uptake in oarsmen during training. Br Heart J 1981 0.95
49 High-dose interferon-alpha2a exerts potent activity against human immunodeficiency virus type 1 not associated with antitumor activity in subjects with Kaposi's sarcoma. J Infect Dis 1997 0.95
50 Diarrhoea in HIV-infected patients: no evidence of cytokine-mediated inflammation in jejunal mucosa. AIDS 1995 0.92
51 Glomerular lesions and opportunistic infections of the kidney in AIDS: an autopsy study of 47 cases. Adv Exp Med Biol 1989 0.92
52 Clinical features and risk factors of lactic acidosis following long-term antiretroviral therapy: 4 fatal cases. Int J STD AIDS 2000 0.92
53 Resumption of HIV antigen production during continuous zidovudine treatment. Lancet 1988 0.91
54 Anorectal surgery in human immunodeficiency virus-infected patients. Clinical outcome in relation to immune status. Dis Colon Rectum 1995 0.90
55 Diversity of the T-cell receptor BV repertoire in HIV-1-infected patients reflects the biphasic CD4+ T-cell repopulation kinetics during highly active antiretroviral therapy. AIDS 1998 0.88
56 Persistence of human immunodeficiency virus antigenemia in patients with the acquired immunodeficiency syndrome treated with a reverse transcriptase inhibitor, suramin. Ten-patient case-control study. Arch Intern Med 1988 0.88
57 Patterns of T-cell repopulation, virus load reduction, and restoration of T-cell function in HIV-infected persons during therapy with different antiretroviral agents. J Acquir Immune Defic Syndr Hum Retrovirol 1997 0.88
58 Mycobacterium xenopi in HIV-infected patients: an emerging pathogen. AIDS 1998 0.87
59 The effect of treatment intensification in HIV-infection: a study comparing treatment with ritonavir/saquinavir and ritonavir/saquinavir/stavudine. Prometheus Study Group. AIDS 2000 0.87
60 Selection by AZT and rapid replacement in the absence of drugs of HIV type 1 resistant to multiple nucleoside analogs. AIDS Res Hum Retroviruses 2001 0.86
61 Cellular and humoral immunity in various cohorts of male homosexuals in relation to infection with human immunodeficiency virus. Neth J Med 1989 0.86
62 Otorhinolaryngological findings in AIDS patients: a study of 63 cases. Arch Otorhinolaryngol 1987 0.86
63 Evaluation of a second-generation nucleic acid sequence-based amplification assay for quantification of HIV type 1 RNA and the use of ultrasensitive protocol adaptations. AIDS Res Hum Retroviruses 2000 0.86
64 Local excision and mucosal advancement for anorectal ulceration in patients infected with human immunodeficiency virus. Br J Surg 1995 0.86
65 HIV seropositivity and tuberculosis in a large general hospital in Malawi. Trop Geogr Med 1990 0.85
66 Low antigenicity of HIV-1 rev: rev-specific antibody response of limited value as correlate of rev gene expression and disease progression. AIDS Res Hum Retroviruses 1989 0.84
67 Decreased exposure to saquinavir in HIV-1-infected patients after long-term antiretroviral therapy including ritonavir and saquinavir. AIDS 2000 0.83
68 Decline of HIV antigen levels in cerebrospinal fluid during treatment with low-dose zidovudine. AIDS 1988 0.82
69 [The acquired immunodeficiency syndrome (AIDS)]. Ned Tijdschr Geneeskd 1983 0.81
70 Results of long-term follow-up of HIV-infected patients treated with lamivudine monotherapy, followed by a combination of lamivudine and zidovudine. Antivir Ther 1997 0.81
71 Common health problems in HIV-infected travelers to the (sub)tropics. J Travel Med 1999 0.81
72 HIV infection and squamous cell carcinoma of sun-exposed skin. AIDS 1990 0.81
73 AIDS dementia complex and didanosine. Lancet 1994 0.80
74 Determination of 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG) in biological fluids by reverse-phase high pressure liquid chromatography. Pharm Weekbl Sci 1987 0.80
75 No beneficial effect of interferon-gamma treatment in 2 human immunodeficiency virus-infected patients with Mycobacterium avium complex infection. Clin Infect Dis 2001 0.80
76 Antiretroviral treatment: state of the art and future directions. AIDS 1991 0.80
77 Amprolium for coccidiosis in AIDS. Lancet 1984 0.80
78 T-cell progenitor function during progressive human immunodeficiency virus-1 infection and after antiretroviral therapy. Blood 2000 0.80
79 Summary of the international consensus symposium on management of HIV, CMV and hepatitis virus infections. Antiviral Res 1998 0.80
80 Prediction of infarct size from serial CK determinations: evaluation by clinical studies and computer simulation. Clin Chim Acta 1979 0.80
81 Impact of diarrhoea and faecal incontinence on the daily life of HIV-infected patients. AIDS Care 1998 0.79
82 General operative aspects of human immunodeficiency virus infection and acquired immunodeficiency syndrome. J Am Coll Surg 1995 0.79
83 Selective inhibition of syncytium-inducing and nonsyncytium-inducing HIV-1 variants in individuals receiving didanosine or zidovudine, respectively. J Clin Invest 1997 0.79
84 Biochemical and circulatory parameters during purely mental stress. Acta Med Scand 1981 0.79
85 Effects of nandrolone decanoate compared with placebo or testosterone on HIV-associated wasting. HIV Med 2006 0.79
86 Ocular and neurological complications of varicella zoster virus infection in a patient with AIDS. AIDS 1996 0.78
87 Acquired immune deficiency syndrome, altered T cell subset ratios, and cytomegalovirus infections among male homosexuals in The Netherlands. Antibiot Chemother (1971) 1983 0.78
88 T cell expansions in lymph nodes and peripheral blood in HIV-1-infected individuals: effect of antiretroviral therapy. AIDS 2001 0.78
89 Invasive external otitis caused by Aspergillus fumigatus in two patients with AIDS. AIDS 1991 0.77
90 [CBO guidelines 'Antiretroviral therapy in the Netherlands']. Ned Tijdschr Geneeskd 2001 0.77
91 Macronodular adrenocortical hyperplasia in a postmenopausal woman. Neth J Med 2004 0.77
92 Can the course of high dose cotrimoxazole for Pneumocystis carinii pneumonia in AIDS be shorter? A possible solution to the problem of cotrimoxazole toxicity. J Intern Med 1990 0.77
93 [Zidovudine therapy in 141 patients with symptoms of HIV infection; a multicenter study]. Ned Tijdschr Geneeskd 1990 0.76
94 Increased numbers of granzyme-B-expressing cytotoxic T-lymphocytes in the small intestine of HIV-infected patients. J Acquir Immune Defic Syndr Hum Retrovirol 1996 0.76
95 Implantation of cultured thymic fragments in patients with acquired immunodeficiency syndrome. Arch Intern Med 1986 0.76
96 Fansidar and Pneumocystis carinii pneumonia. Ann Intern Med 1988 0.76
97 Continued zidovudine and interferon-alpha therapy in Kaposi sarcoma and the acquired immunodeficiency syndrome (AIDS) Ann Intern Med 1990 0.75
98 Cultured human thymus epithelial monolayer cells induce CD4 expression on mononuclear cells of AIDS patients in vitro. Clin Exp Immunol 1986 0.75
99 Clarithromycin therapy for Mycobacterium avium complex bacteremia. Ann Intern Med 1995 0.75
100 The Concorde trial. Lancet 1993 0.75
101 Cardiovascular health in the tenth decade. Br Med J 1978 0.75
102 [AIDS and dentistry. Introduction to terminology]. Ned Tijdschr Tandheelkd 1987 0.75
103 Lack of activity of zidovudine in AIDS-associated Kaposi's sarcoma. AIDS 1989 0.75
104 Effect of physical exercise on blood lipids and adipose tissue composition in young healthy men. Atherosclerosis 1984 0.75
105 Treatment of poor prognosis epidemic Kaposi's sarcoma with doxorubicin, bleomycin, vindesine and recombinant human granulocyte-monocyte colony stimulating factor (rh GM-CSF). Eur J Cancer 1995 0.75
106 [Changed criteria in the diagnosis of AIDS]. Ned Tijdschr Geneeskd 1988 0.75
107 [Generalized histoplasmosis in 3 patients with an HIV infection]. Ned Tijdschr Geneeskd 1990 0.75
108 [HIV-1 therapy in the Netherlands; virological and immunological response to antiretroviral therapy]. Ned Tijdschr Geneeskd 2001 0.75
109 Decline of HIV-1 RNA in cerebrospinal fluid during zidovudine treatment. Antivir Ther 1996 0.75
110 Low incidence of anti-interferon-alpha antibodies in patients treated with interferon-alpha-2a for AIDS-associated Kaposi's sarcoma. Int J STD AIDS 1990 0.75
111 Therapy for cytomegalovirus polyradiculomyelitis in patients with AIDS: treatment with ganciclovir. AIDS 1990 0.75
112 [HIV and dentistry. Part 3. HIV infection: pathogenesis, epidemiology, definitions and classification]. Ned Tijdschr Tandheelkd 1994 0.75
113 [Bacterial endocarditis in drug users]. Ned Tijdschr Geneeskd 1981 0.75
114 Reduction of myocardial infarct size by early intervention. Neth J Med 1977 0.75
115 AIDS in The Netherlands. Clinical and microbiological data on 36 cases. Neth J Med 1985 0.75
116 [Does latent HIV-infection exist?]. Ned Tijdschr Geneeskd 1994 0.75
117 [AIDS: new developments. VI. HIV reservoirs during intensive antiretroviral treatment]. Ned Tijdschr Geneeskd 1998 0.75
118 Gallium-67 lung scintigraphy in patients with acquired immune deficiency syndrome (AIDS). Eur J Respir Dis 1986 0.75
119 [AIDS and tuberculosis; a retrospective study in 225 patients with AIDS]. Ned Tijdschr Geneeskd 1989 0.75
120 [Pneumocystis carinii pneumonia in patients with AIDS]. Ned Tijdschr Geneeskd 1987 0.75
121 [AIDS: a clinical diagnosis, hence one with pitfalls]. Ned Tijdschr Geneeskd 1985 0.75
122 [Tuberculosis: not a 'conquered' disease]. TVZ 1993 0.75
123 A dose-ranging study to evaluate the antiretroviral activity and safety of amprenavir alone and in combination with abacavir in HIV-infected adults with limited antiretroviral experience. Antivir Ther 2001 0.75
124 [Disease symptoms and clinical course in the first 100 patients with AIDS]. Ned Tijdschr Geneeskd 1987 0.75
125 AIDS and tuberculosis. Results of a retrospective study in 225 AIDS patients. Bull Int Union Tuberc Lung Dis 1990 0.75
126 Serodiagnostic profiles of HIV and HIV pathogenesis in vivo. Haematologia (Budap) 1988 0.75
127 Combined zidovudine and interferon-alpha treatment in patients with AIDS-associated Kaposi's sarcoma. J Intern Med 1991 0.75
128 [Medical dilemma of AIDS]. Ned Tijdschr Tandheelkd 1987 0.75
129 Additive or sequential nucleoside analogue therapy compared with continued zidovudine monotherapy in human immunodeficiency virus-infected patients with advanced disease does not prolong survival: an observational study. J Infect Dis 1997 0.75
130 [Acquired immunodeficiency syndrome (AIDS) in Africa]. Ned Tijdschr Geneeskd 1985 0.75
131 [AIDS and dentistry. History, general diagnosis and medical care--an overview]. Ned Tijdschr Tandheelkd 1987 0.75
132 Attitudes of health-care workers towards AIDS at three Dutch hospitals. AIDS 1991 0.75
133 [Interim advice from the Public Health Council concerning patients with acquired immunodeficiency syndrome]. Ned Tijdschr Geneeskd 1984 0.75
134 Severe complications of perianal sepsis in patients with human immunodeficiency virus. Br J Surg 1996 0.75
135 Etoposide for epidemic Kaposi's sarcoma: a phase II study. Eur J Cancer Clin Oncol 1988 0.75
136 Effects of recombinant human granulocyte colony-stimulating factor on leucopenia in zidovudine-treated patients with AIDS and AIDS related complex, a phase I/II study. Br J Haematol 1991 0.75