Published in FASEB J on June 01, 1996
Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. Proc Natl Acad Sci U S A (1997) 2.49
Estradiol repression of tumor necrosis factor-alpha transcription requires estrogen receptor activation function-2 and is enhanced by coactivators. Proc Natl Acad Sci U S A (1999) 1.26
Differential presentation of protein interaction surfaces on the androgen receptor defines the pharmacological actions of bound ligands. Chem Biol (2009) 1.14
Molecular determinants of tissue selectivity in estrogen receptor modulators. Proc Natl Acad Sci U S A (1997) 1.10
Eel calcitonin (elcatonin) suppressed callus remodeling but did not interfere with fracture healing in the femoral fracture model of cynomolgus monkeys. J Bone Miner Metab (2009) 0.93
Estrogenic modulation of brain activity: implications for schizophrenia and Parkinson's disease. J Psychiatry Neurosci (2002) 0.92
Comparative effects of 17beta-estradiol, raloxifene and genistein on bone 3D microarchitecture and volumetric bone mineral density in the ovariectomized mice. Osteoporos Int (2008) 0.89
Selective estrogen receptor modulators: tissue specificity and clinical utility. Clin Interv Aging (2014) 0.88
Induction and inhibition of oocyte maturation by EDCs in zebrafish. Reprod Biol Endocrinol (2005) 0.87
Estrogen receptor alpha interacts with mitochondrial protein HADHB and affects beta-oxidation activity. Mol Cell Proteomics (2012) 0.87
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro. Br J Pharmacol (2007) 0.87
Foxl2, a forkhead transcription factor, modulates nonclassical activity of the estrogen receptor-alpha. Endocrinology (2009) 0.83
Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis. Arthritis Res Ther (2011) 0.82
Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1*/* mice with collagen-induced chronic arthritis. BMC Musculoskelet Disord (2010) 0.81
Changes in 5-HT1A receptor binding and G-protein activation in the rat brain after estrogen treatment: comparison with tamoxifen and raloxifene. J Psychiatry Neurosci (2005) 0.81
The evolution of selective estrogen receptor modulators in osteoporosis therapy. Climacteric (2012) 0.80
Estrogen or raloxifene during postmenopausal weight loss: adiposity and cardiometabolic outcomes. Obesity (Silver Spring) (2013) 0.79
The differential effects of bisphosphonates, SERMS (selective estrogen receptor modulators), and parathyroid hormone on bone remodeling in osteoporosis. Clin Interv Aging (2007) 0.78
Estrogens and selective estrogen receptor modulators regulate gene and protein expression in the mesenteric arteries. Vascul Pharmacol (2011) 0.78
Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer. World J Surg Oncol (2010) 0.77
Raloxifene as an Adjunctive Treatment for Postmenopausal Women With Schizophrenia: A 24-Week Double-Blind, Randomized, Parallel, Placebo-Controlled Trial. Schizophr Bull (2015) 0.76
Induction of mitochondrial apoptotic pathway by raloxifene and estrogen in human endometrial stromal ThESC cell line. Arch Med Sci (2016) 0.75
The effect of selective estrogen receptor modulators on type 2 diabetes onset in women: Basic and clinical insights. J Diabetes Complications (2017) 0.75
Effects of ospemifene on the female reproductive and urinary tracts: translation from preclinical models into clinical evidence. Menopause (2015) 0.75
Estrogen Promotes Hepatic Synthesis of Long-Chain Polyunsaturated Fatty Acids by Regulating ELOVL5 at Post-Transcriptional Level in Laying Hens. Int J Mol Sci (2017) 0.75
Experimental hepatitis E in pregnant rhesus monkeys: failure to transmit hepatitis E virus (HEV) to offspring and evidence of naturally acquired antibodies to HEV. J Infect Dis (1995) 1.65
Experimental assessment of small intestinal submucosa as a bladder wall substitute. Urology (1995) 1.46
Inhibition of glycinamide ribonucleotide formyltransferase results in selective inhibition of macrophage cytokine secretion in vitro and in vivo efficacy in rat adjuvant arthritis. Clin Exp Rheumatol (2005) 1.38
Regenerative urinary bladder augmentation using small intestinal submucosa: urodynamic and histopathologic assessment in long-term canine bladder augmentations. J Urol (1996) 1.20
Emerging therapies for the prevention or treatment of postmenopausal osteoporosis. J Med Chem (1999) 1.13
Environmental estrogens: effects on cholesterol lowering and bone in the ovariectomized rat. J Steroid Biochem Mol Biol (1996) 1.10
Molecular determinants of tissue selectivity in estrogen receptor modulators. Proc Natl Acad Sci U S A (1997) 1.10
Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifene. J Med Chem (1997) 1.09
Rabbit urethral regeneration using small intestinal submucosa onlay grafts. Urology (1998) 1.08
Discovery and synthesis of [6-hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]-2-(4-hydroxyphenyl)]b enzo[b]thiophene: a novel, highly potent, selective estrogen receptor modulator. J Med Chem (1997) 1.07
Raloxifene is a tissue-selective agonist/antagonist that functions through the estrogen receptor. Ann N Y Acad Sci (1995) 1.07
Characterization of small intestinal submucosa regenerated canine detrusor: assessment of reinnervation, in vitro compliance and contractility. J Urol (1996) 1.05
Selective estrogen receptor modulators and postmenopausal women's health. J Womens Health (1997) 1.04
Protection of mice from inhaled ricin by vaccination with ricin or by passive treatment with heterologous antibody. Vaccine (1993) 1.04
Detrusor regeneration in the rat using porcine small intestinal submucosal grafts: functional innervation and receptor expression. J Urol (1996) 1.03
Biochemical effects of estrogen on articular cartilage in ovariectomized sheep. Osteoarthritis Cartilage (1997) 1.02
Arzoxifene, a new selective estrogen receptor modulator for chemoprevention of experimental breast cancer. Cancer Res (2001) 0.97
Evaluation of the major metabolites of raloxifene as modulators of tissue selectivity. J Steroid Biochem Mol Biol (1997) 0.92
Infection of Macaca radiata with viruses of the tick-borne encephalitis group. Microb Pathog (1992) 0.92
Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats. J Pharmacol Exp Ther (1995) 0.90
Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res (1992) 0.90
The effects of raloxifene on tibia histomorphometry in ovariectomized rats. Endocrinology (1994) 0.90
Aerosol infection of rhesus macaques with Junin virus. Intervirology (1992) 0.90
Synthesis and pharmacology of conformationally restricted raloxifene analogues: highly potent selective estrogen receptor modulators. J Med Chem (1998) 0.89
Advantages of raloxifene over alendronate or estrogen on nonreproductive and reproductive tissues in the long-term dosing of ovariectomized rats. J Pharmacol Exp Ther (1996) 0.89
Raloxifene and estradiol benzoate both fully restore hippocampal choline acetyltransferase activity in ovariectomized rats. Brain Res (1999) 0.89
Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus. Biol Reprod (2004) 0.89
No direct neuronotoxicity by HIV-1 virions or culture fluids from HIV-1-infected T cells or monocytes. AIDS Res Hum Retroviruses (1992) 0.88
Selective estrogen receptor modulators: tissue selectivity and differential uterine effects. Climacteric (1999) 0.88
Raloxifene preserves bone strength and bone mass in ovariectomized rats. Endocrinology (1994) 0.88
Morphine-induced alterations in plasma and tissue cholesterol levels. Life Sci (1987) 0.87
Estrogen and raloxifene stimulate transforming growth factor-beta 3 gene expression in rat bone: a potential mechanism for estrogen- or raloxifene-mediated bone maintenance. Endocrinology (1996) 0.86
LY353381.HCl: a novel raloxifene analog with improved SERM potency and efficacy in vivo. J Pharmacol Exp Ther (1998) 0.85
The selective estrogen receptor modulator, raloxifene: an overview of nonclinical pharmacology and reproductive and developmental testing. Reprod Toxicol (1998) 0.84
Raloxifene inhibits bone turnover and prevents further cancellous bone loss in adult ovariectomized rats with established osteopenia. Endocrinology (1996) 0.84
The effect of raloxifene on coronary arteries in aged ovariectomized ewes. J Vet Pharmacol Ther (2000) 0.83
Effect of weight manipulation on bone loss due to ovariectomy and the protective effects of estrogen in the rat. Calcif Tissue Int (1993) 0.83
The nongenotropic synthetic ligand 4-estren-3alpha17beta-diol is a high-affinity genotropic androgen receptor agonist. Mol Pharmacol (2004) 0.83
Mechanism of action of estrogens and selective estrogen receptor modulators. Vitam Horm (2000) 0.83
Differential responses of estrogen target tissues in rats including bone to clomiphene, enclomiphene, and zuclomiphene. Endocrinology (1998) 0.81
Anti-inflammatory activity of pergolide, a dopamine receptor agonist. J Pharmacol Exp Ther (1991) 0.81
Dissociation of immunosuppression by chlorpromazine and trifluoperazine from pharmacologic activities as dopamine antagonists. Int J Immunopharmacol (1991) 0.80
Stress, endogenous opioids and salt intake. Appetite (1984) 0.79
Dual-energy x-ray absorptiometry of raloxifene effects on the lumbar vertebrae and femora of ovariectomized rats. J Bone Miner Res (1994) 0.79
Pulmonary actions of anandamide, an endogenous cannabinoid receptor agonist, in guinea pigs. Eur J Pharmacol (1998) 0.79
Serotonin-induced paw edema in the rat: pharmacological profile. Gen Pharmacol (1995) 0.78
Pharmacologic manipulation of graft versus host induced splenomegaly. Agents Actions (1992) 0.78
Central and peripheral temperature changes in sheep following ovariectomy. Maturitas (2003) 0.78
The selective oestrogen receptor modulator, LY362321, is not neuroprotective in a rat model of transient focal ischaemia. J Neuroendocrinol (2008) 0.78
Conditioned immunosuppression of a murine delayed type hypersensitivity response: dissociation from corticosterone elevation. Brain Behav Immun (1991) 0.77
Hypocholesterolemic activity of raloxifene (LY139481): pharmacological characterization as a selective estrogen receptor modulator. J Pharmacol Exp Ther (1997) 0.77
Effects of wortmannin analogs on bone in vitro and in vivo. J Pharmacol Exp Ther (1996) 0.77
Dose-response effects of estradiol implants on bone mineral density in ovariectomized ewes. Bone (1995) 0.76
Opioid and non-opioid components of insulin-induced feeding. Pharmacol Biochem Behav (1986) 0.76
Comment on lack of effect of raloxifene on coronary artery atherosclerosis of postmenopausal monkeys. J Clin Endocrinol Metab (1998) 0.75
Effects of 2% sodium chloride imbibition on various opiate related hyperphagic conditions. Pharmacol Biochem Behav (1985) 0.75
Clomiphene prevents cancellous bone loss from tibia of ovariectomized rats. Endocrinology (1997) 0.75
Presence of dynorphin-like immunoreactivity but not opiate binding in Walker-256 tumors. Life Sci (1985) 0.75
Nocturnal depletion of hypothalamic dynorphin in anorexic Walker-256 tumor-bearing rats. Pharmacol Biochem Behav (1988) 0.75
Pharmacologic manipulation of a four day murine delayed type hypersensitivity model. Agents Actions (1993) 0.75
Aerosolized LTB4 produces delayed onset increases in pulmonary gas trapping. Prostaglandins Leukot Essent Fatty Acids (1996) 0.75
Development and characterization of a porcine model to study osteoclast differentiation and activity. Bone (1996) 0.75
Glucocorticoid hepatopathy: effect on receptor-mediated endocytosis of asialoglycoproteins. Biochem Med Metab Biol (1991) 0.75
Effects of prolonged ethinyl estradiol treatment on calcium channel binding and in vivo calcium-mediated hemodynamic responses in ovariectomized rats. J Pharmacol Exp Ther (1997) 0.75
Differential inhibition by propranolol of feeding induced in rats by various stimuli. Pharmacol Biochem Behav (1984) 0.75
Assessment of dynorphin-A depletion in the anorexia of Walker-256 tumor bearing rats. Physiol Behav (1985) 0.75
Photochemical synthesis of N-arylbenzophenanthridine selective estrogen receptor modulators (serms). J Med Chem (2001) 0.75
Dual-energy X-ray absorptiometry in sheep: experiences with in vivo and ex vivo studies. Bone (1995) 0.75
CNS tissue levels of dynorphin-A immunoreactivity and the anorexia associated with sodium chloride imbibition in the rat. Peptides (1985) 0.75
Characterization of simian immunodeficiency virus (SIV) infected AA-2 cells by SEM and immunoelectron microscopy. Microsc Res Tech (1994) 0.75