Published in Nat Struct Biol on July 01, 1996
Trapping of organic blockers by closing of voltage-dependent K+ channels: evidence for a trap door mechanism of activation gating. J Gen Physiol (1997) 3.13
An improved relaxed complex scheme for receptor flexibility in computer-aided drug design. J Comput Aided Mol Des (2008) 2.16
Automated docking of ligands to an artificial active site: augmenting crystallographic analysis with computer modeling. J Comput Aided Mol Des (2003) 1.55
Probing molecular docking in a charged model binding site. J Mol Biol (2006) 1.17
Predictive power of molecular dynamics receptor structures in virtual screening. J Chem Inf Model (2011) 0.93
Stereo-selectivity of human serum albumin to enantiomeric and isoelectronic pollutants dissected by spectroscopy, calorimetry and bioinformatics. PLoS One (2011) 0.93
Excision of a proposed electron transfer pathway in cytochrome c peroxidase and its replacement by a ligand-binding channel. Protein Sci (2002) 0.92
The protein environment surrounding tyrosyl radicals D. and Z. in photosystem II: a difference Fourier-transform infrared spectroscopic study. Biophys J (1998) 0.87
Disabling TNF receptor signaling by induced conformational perturbation of tryptophan-107. Proc Natl Acad Sci U S A (2005) 0.86
The impact of introducing a histidine into an apolar cavity site on docking and ligand recognition. J Med Chem (2013) 0.82
Outliers in SAR and QSAR: is unusual binding mode a possible source of outliers? J Comput Aided Mol Des (2007) 0.80
Thermodynamic analysis of halide binding to haloalkane dehalogenase suggests the occurrence of large conformational changes. Protein Sci (1999) 0.78
Predicting Binding Free Energies. Annu Rev Biophys (2017) 0.78
Trapping of peptide-based surrogates in an artificially created channel of cytochrome c peroxidase. Protein Sci (2003) 0.77
Impact of Proximal and Distal Pocket Site-Directed Mutations on the Ferric/Ferrous Heme Redox Potential of Yeast Cytochrome-c-Peroxidase. Theor Chem Acc (2011) 0.75
Structure of a protein photocycle intermediate by millisecond time-resolved crystallography. Science (1997) 3.25
Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity. Mol Cell (2000) 2.98
Self-assembling organic nanotubes based on a cyclic peptide architecture. Nature (1993) 2.84
Copper binding to the prion protein: structural implications of four identical cooperative binding sites. Proc Natl Acad Sci U S A (1999) 2.44
Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III. Science (1992) 2.17
Identification by ENDOR of Trp191 as the free-radical site in cytochrome c peroxidase compound ES. Science (1989) 2.02
Refined crystal structure of Cd, Zn metallothionein at 2.0 A resolution. J Mol Biol (1991) 1.70
The Asp-His-Fe triad of cytochrome c peroxidase controls the reduction potential, electronic structure, and coupling of the tryptophan free radical to the heme. Biochemistry (1993) 1.49
Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo. J Biol Chem (2001) 1.47
Structure of Haemophilus influenzae Fe(+3)-binding protein reveals convergent evolution within a superfamily. Nat Struct Biol (1997) 1.40
A simple and efficient procedure for generating random point mutations and for codon replacements using mixed oligodeoxynucleotides. DNA (1988) 1.34
Primary structure of a photoactive yellow protein from the phototrophic bacterium Ectothiorhodospira halophila, with evidence for the mass and the binding site of the chromophore. Protein Sci (1993) 1.19
Small molecule binding to an artificially created cavity at the active site of cytochrome c peroxidase. Biochemistry (1994) 1.18
Identification of a porphyrin pi cation radical in ascorbate peroxidase compound I. Biochemistry (1995) 1.18
Crystallographic and biochemical analyses of the metal-free Haemophilus influenzae Fe3+-binding protein. Biochemistry (2001) 1.17
The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 A resolution. Nat Struct Biol (1999) 1.11
Microsomal cytochrome P450 2C5: comparison to microbial P450s and unique features. J Inorg Biochem (2000) 1.11
Comprehensive explanation of the anomalous EPR spectra of wild-type and mutant cytochrome c peroxidase compound ES. Biochemistry (1993) 1.09
Crystal structure of Aplysia ADP ribosyl cyclase, a homologue of the bifunctional ectozyme CD38. Nat Struct Biol (1996) 1.07
Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content. Phytomedicine (2002) 1.05
The crystal structure of lysin, a fertilization protein. Science (1993) 1.05
Biochemical purification and crystallographic characterization of the fiber-forming protein pilin from Neisseria gonorrhoeae. J Biol Chem (1990) 1.03
Crystal structure of dUTP pyrophosphatase from feline immunodeficiency virus. Protein Sci (1996) 1.01
Intracellular Localization of Two Enzymes Involved in Coumarin Biosynthesis in Melilotus alba. Plant Physiol (1980) 0.98
Atomic structure of a cytochrome c' with an unusual ligand-controlled dimer dissociation at 1.8 A resolution. J Mol Biol (1993) 0.98
Introduction of novel substrate oxidation into cytochrome c peroxidase by cavity complementation: oxidation of 2-aminothiazole and covalent modification of the enzyme. Biochemistry (1997) 0.98
Crystallographic characterization of a photoactive yellow protein with photochemistry similar to sensory rhodopsin. J Biol Chem (1986) 0.96
Rational design of a functional metalloenzyme: introduction of a site for manganese binding and oxidation into a heme peroxidase. Biochemistry (1998) 0.95
Multifrequency high-field EPR study of the tryptophanyl and tyrosyl radical intermediates in wild-type and the W191G mutant of cytochrome c peroxidase. J Am Chem Soc (2001) 0.93
Protein conformer selection by ligand binding observed with crystallography. Protein Sci (1998) 0.92
A rapid droplet method for Sanger dideoxy sequencing. Biotechniques (1988) 0.90
The peroxide complex of yeast cytochrome c peroxidase contains two distinct radical species, neither of which resides at methionine 172 or tryptophan 51. J Biol Chem (1987) 0.90
The role of aspartate-235 in the binding of cations to an artificial cavity at the radical site of cytochrome c peroxidase. Protein Sci (1995) 0.90
Cysteine sulfoxide derivatives in Petiveria alliacea. Phytochemistry (2001) 0.90
Construction of a bisaquo heme enzyme and binding by exogenous ligands. Proc Natl Acad Sci U S A (1994) 0.89
Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 2. Effects on heme coordination and function. Biochemistry (2001) 0.87
Preliminary X-ray diffraction studies of acyl carrier protein from Escherichia coli. J Mol Biol (1985) 0.86
The heme and Fe4S4 cluster in the crystallographic structure of Escherichia coli sulfite reductase. J Biol Chem (1986) 0.86
Crystallization and crystallographic characterization of the iron-sulfur-containing DNA-repair enzyme endonuclease III from Escherichia coli. J Mol Biol (1992) 0.86
Oxidized and reduced Azotobacter vinelandii ferredoxin I at 1.4 A resolution: conformational change of surface residues without significant change in the [3Fe-4S]+/0 cluster. Biochemistry (1999) 0.86
Unusual oxidative chemistry of N(omega)-hydroxyarginine and N-hydroxyguanidine catalyzed at an engineered cavity in a heme peroxidase. J Biol Chem (2000) 0.85
Crystallographic characterization of a Cu,Zn superoxide dismutase from Photobacterium leiognathi. J Mol Biol (1990) 0.84
Structure of Azotobacter vinelandii 7Fe ferredoxin at 1.35 A resolution and determination of the [Fe-S] bonds with 0.01 A accuracy. J Mol Biol (1998) 0.83
Inhibition of neurogenic inflammation by the Amazonian herbal medicine sangre de grado. J Invest Dermatol (2001) 0.83
Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry (2001) 0.82
Understanding the structure and antigenicity of gonococcal pili. Rev Infect Dis (1988) 0.79
Three dimensional structure of bacterial pili. Antonie Van Leeuwenhoek (1987) 0.79
Enhanced oxidation of aniline derivatives by two mutants of cytochrome c peroxidase at tryptophan 51. J Biol Chem (1993) 0.78
A distal histidine mutant (H52Q) of yeast cytochrome c peroxidase catalyzes the oxidation of H(2)O(2) instead of its reduction. J Am Chem Soc (2001) 0.78
Studies of the radical species in compound ES of cytochrome c peroxidase altered by site-directed mutagenesis. Proc Natl Acad Sci U S A (1986) 0.77
Investigating resins for solid phase organic synthesis: the relationship between swelling and microenvironment as probed by EPR and fluorescence spectroscopy. J Comb Chem (2000) 0.76
S-aryl-L-cysteine sulphoxides and related organosulphur compounds alter oral biofilm development and AI-2-based cell-cell communication. J Appl Microbiol (2014) 0.76
Altering substrate specificity at the heme edge of cytochrome c peroxidase. Biochemistry (1996) 0.76
Effect of axial ligand plane reorientation on electronic and electrochemical properties observed in the A67V mutant of rat cytochrome b5. Biochemistry (1997) 0.76
Magnetic circular dichroism studies of the active site heme coordination sphere of exogenous ligand-free ferric cytochrome c peroxidase from yeast: effects of sample history and pH. J Inorg Biochem (1999) 0.76
Preliminary X-ray diffraction studies on the hemoprotein subunit of Escherichia coli sulfite reductase. J Mol Biol (1982) 0.76
Mechanism and atomic structure of superoxide dismutase. Free Radic Res Commun (1991) 0.75
Impact of Proximal and Distal Pocket Site-Directed Mutations on the Ferric/Ferrous Heme Redox Potential of Yeast Cytochrome-c-Peroxidase. Theor Chem Acc (2011) 0.75
Living with metal ions. Nat Struct Biol (1998) 0.75
Horseradish peroxidase Phe172-->Tyr mutant. Sequential formation of compound I with a porphyrin radical cation and a protein radical. J Biol Chem (1995) 0.75
Influence of protein environment on magnetic circular dichroism spectral properties of ferric and ferrous ligand complexes of yeast cytochrome c peroxidase. Biospectroscopy (1999) 0.75
[Computer model of 3D structure of cytochrome P450 2B4]. Vopr Med Khim (2002) 0.75
Electric fields in active sites: substrate switching from null to strong fields in thiol- and selenol-subtilisins. Biochemistry (1999) 0.75
The first structure of a microsomal P450--implications for drug discovery. Curr Opin Drug Discov Devel (2001) 0.75
Purification, crystallization and space group determination of DNA repair enzyme exonuclease III from E. coli. J Mol Biol (1993) 0.75