C F Clarke

Author PubWeight™ 46.49‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging. Mamm Genome 1999 9.96
2 The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis. J Biol Chem 1996 1.70
3 A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants. J Biol Chem 2001 1.61
4 Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis. J Bacteriol 2000 1.51
5 Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis. Biochemistry 1996 1.49
6 A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants. Proc Natl Acad Sci U S A 2001 1.40
7 Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis. J Biol Chem 1998 1.38
8 Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. J Biol Chem 1999 1.36
9 Regulation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A synthase and the chromosomal localization of the human gene. J Biol Chem 1986 1.36
10 Enhanced sensitivity of ubiquinone-deficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids. Proc Natl Acad Sci U S A 1996 1.34
11 A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene. J Bacteriol 1997 1.31
12 Yeast COQ4 encodes a mitochondrial protein required for coenzyme Q synthesis. Arch Biochem Biophys 2001 1.16
13 Genetic evidence for a multi-subunit complex in the O-methyltransferase steps of coenzyme Q biosynthesis. Biochim Biophys Acta 2000 1.16
14 Diurnal rhythm of rat liver mRNAs encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase. Correlation of functional and total mRNA levels with enzyme activity and protein. J Biol Chem 1984 1.14
15 3-Hexaprenyl-4-hydroxybenzoic acid forms a predominant intermediate pool in ubiquinone biosynthesis in Saccharomyces cerevisiae. Arch Biochem Biophys 1995 1.10
16 Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis. J Biol Chem 2000 1.10
17 Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA levels in rat liver. Proc Natl Acad Sci U S A 1983 1.10
18 Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis. J Biol Chem 1997 1.09
19 Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis. Cell Mol Life Sci 2009 1.08
20 Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants. Mol Aspects Med 1997 1.04
21 Testis-specific transcription initiation sites of rat farnesyl pyrophosphate synthetase mRNA. Mol Cell Biol 1990 1.00
22 Transcriptional regulation of the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene in rat liver. J Biol Chem 1985 0.98
23 Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. Arch Biochem Biophys 1996 0.95
24 Ubiquinone biosynthesis in eukaryotic cells: tissue distribution of mRNA encoding 3,4-dihydroxy-5-polyprenylbenzoate methyltransferase in the rat and mapping of the COQ3 gene to mouse chromosome 4. Arch Biochem Biophys 1994 0.88
25 Genetic evidence for coenzyme Q requirement in plasma membrane electron transport. J Bioenerg Biomembr 1998 0.88
26 Cloning of a rat cDNA encoding dihydroxypolyprenylbenzoate methyltransferase by functional complementation of a Saccharomyces cerevisiae mutant deficient in ubiquinone biosynthesis. Gene 1994 0.87
27 Angel trumpet lily poisoning in five adolescents: clinical findings and management. J Paediatr Child Health 1999 0.86
28 Coenzyme Q6 and iron reduction are responsible for the extracellular ascorbate stabilization at the plasma membrane of Saccharomyces cerevisiae. J Biol Chem 1998 0.85
29 Dispersed family of human genes with sequence similarity to farnesyl pyrophosphate synthetase. Genomics 1989 0.84
30 Progression of borderline increases in albuminuria in adolescents with insulin-dependent diabetes mellitus. Diabet Med 1997 0.84
31 Ambulatory blood pressure, microalbuminuria, and autonomic neuropathy in adolescents with type 1 diabetes. Diabetes Care 2000 0.83
32 Autoxidation of ubiquinol-6 is independent of superoxide dismutase. Biochemistry 1996 0.79
33 Testis-specific transcripts of rat farnesyl pyrophosphate synthetase are developmentally regulated and localized to haploid germ cells. Biol Reprod 1991 0.78
34 Prevalence of coeliac disease and longitudinal follow-up of antigliadin antibody status in children and adolescents with type 1 diabetes mellitus. Pediatr Diabetes 2000 0.77
35 Role of mevalonate in regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured cells and their cytoplasts. J Lipid Res 1985 0.77
36 Characterization of Saccharomyces cerevisiae ubiquinone-deficient mutants. Biofactors 1999 0.76
37 Caring for the terminally ill adolescent. Med J Aust 1997 0.75
38 Should pregnant teachers work? N Engl J Med 1972 0.75
39 The Diabetes Control and Complications Trial. Implications for children and adolescents. Australasian Paediatric Endocrine Group. Med J Aust 1995 0.75