Published in Immunol Today on July 01, 1996
Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. J Cell Biol (1998) 2.91
NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses. J Exp Med (1997) 2.66
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin. Genes Dev (1998) 2.37
Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation. J Cell Biol (2001) 2.09
B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J Exp Med (1998) 2.00
Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes. Proc Natl Acad Sci U S A (1998) 1.98
Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments. EMBO J (1998) 1.96
Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nat Cell Biol (2009) 1.94
Isolation and characterization of lymphocyte-like cells from a lamprey. Proc Natl Acad Sci U S A (2002) 1.50
Commitment of common T/Natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay. J Exp Med (1999) 1.20
A conserved tissue-specific structure at a human T-cell receptor beta-chain core promoter. Mol Cell Biol (1997) 1.10
High expression of the HMG box factor sox-13 in arterial walls during embryonic development. Nucleic Acids Res (1998) 1.02
Do lampreys have lymphocytes? The Spi evidence. Proc Natl Acad Sci U S A (2000) 0.99
Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6. J Exp Med (2003) 0.95
The B29 (immunoglobulin beta-chain) gene is a genetic target for early B-cell factor. Mol Cell Biol (1999) 0.95
TCRalpha enhancer activation occurs via a conformational change of a pre-assembled nucleo-protein complex. EMBO J (2000) 0.94
Expression of the mouse pre-T cell receptor alpha gene is controlled by an upstream region containing a transcriptional enhancer. J Exp Med (1999) 0.94
Extinction of expression of the genes encoding haematopoietic cell-restricted transcription factors in T-lymphoma x fibroblast cell hybrids. Immunology (2001) 0.75
Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo. Proc Natl Acad Sci U S A (1980) 16.88
Functional interaction of beta-catenin with the transcription factor LEF-1. Nature (1996) 15.88
Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements. Cell (1985) 8.16
Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo. Proc Natl Acad Sci U S A (1980) 7.31
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell (1988) 6.48
Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev (1994) 6.07
LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]. Genes Dev (1991) 5.95
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev (2001) 5.79
The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures. Cell (1992) 5.24
Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes Dev (1995) 4.34
Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature (1995) 4.14
Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin. Mol Cell Biol (1998) 3.79
LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic. Cell (1997) 3.63
Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature (1995) 3.58
Regulation of LEF-1/TCF transcription factors by Wnt and other signals. Curr Opin Cell Biol (1999) 3.52
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways. Proc Natl Acad Sci U S A (1998) 3.35
Generation of authentic 3' termini of an H2A mRNA in vivo is dependent on a short inverted DNA repeat and on spacer sequences. Cell (1982) 3.35
A tRNA gene of Xenopus laevis contains at least two sites promoting transcription. Nucleic Acids Res (1979) 3.30
Introduction of a mu immunoglobulin gene into the mouse germ line: specific expression in lymphoid cells and synthesis of functional antibody. Cell (1984) 3.24
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity (2000) 3.19
Two regulatory elements for immunoglobulin kappa light chain gene expression. Proc Natl Acad Sci U S A (1984) 2.98
Delimitation of a promoter for RNA polymerase III by means of a functional test. Proc Natl Acad Sci U S A (1979) 2.97
Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice. Genes Dev (1999) 2.94
Delimitation of far upstream sequences required for maximal in vitro transcription of an H2A histone gene. Proc Natl Acad Sci U S A (1982) 2.90
ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function. Genes Dev (1997) 2.78
Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1. Immunity (1998) 2.57
DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1. Genes Dev (1991) 2.56
Lef1 expression is activated by BMP-4 and regulates inductive tissue interactions in tooth and hair development. Genes Dev (1996) 2.42
Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A. Immunity (1999) 2.35
ClaI. a new restriction endonuclease from Caryophanon latum L. Nucleic Acids Res (1981) 2.21
Functional analysis of the replicator structure of lambdoid bacteriophage DNAs. Cold Spring Harb Symp Quant Biol (1979) 2.18
DNA sequences and structural homologies of the replication origins of lambdoid bacteriophages. Nature (1979) 2.13
Extension of chromatin accessibility by nuclear matrix attachment regions. Nature (1997) 2.06
Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development (2000) 2.01
LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites. EMBO J (1993) 2.01
EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes. Immunity (1997) 1.95
Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions. Science (1994) 1.91
Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression. Genes Dev (1993) 1.84
An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene. Proc Natl Acad Sci U S A (1992) 1.80
LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter. Dev Biol (1997) 1.78
Nucleotide sequence of the cro-cII-oop region of bacteriophage 434 DNA. Nucleic Acids Res (1979) 1.78
A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation. EMBO J (1991) 1.65
The immunoglobulin mu enhancer core establishes local factor access in nuclear chromatin independent of transcriptional stimulation. Genes Dev (1993) 1.57
EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains. EMBO J (1995) 1.57
Ebf1 controls early cell differentiation in the embryonic striatum. Development (1999) 1.53
Point mutation in the TATA box curtails expression of sea urchin H2A histone gene in vivo. Nature (1981) 1.51
Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression. Proc Natl Acad Sci U S A (2001) 1.35
Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities. Genes Dev (1991) 1.30
Matrix attachment region-dependent function of the immunoglobulin mu enhancer involves histone acetylation at a distance without changes in enhancer occupancy. Mol Cell Biol (2001) 1.28
Distinct DNA-binding properties of the high mobility group domain of murine and human SRY sex-determining factors. Proc Natl Acad Sci U S A (1994) 1.27
Transcriptional regulation of B-cell differentiation. Curr Opin Immunol (1998) 1.26
Nuclear matrix attachment regions antagonize methylation-dependent repression of long-range enhancer-promoter interactions. Genes Dev (1999) 1.24
TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelial signaling centers and is regulated by Wnt and activin during tooth organogenesis. Dev Biol (2001) 1.24
Purification of early-B-cell factor and characterization of its DNA-binding specificity. Mol Cell Biol (1993) 1.24
Submucosal gland development in the airway is controlled by lymphoid enhancer binding factor 1 (LEF1). Development (1999) 1.24
Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences. Mol Cell Biol (1991) 1.17
Depletion of the predominant B-cell population in immunoglobulin mu heavy-chain transgenic mice. Nature (1987) 1.11
Regulation of gene expression at early stages of B-cell differentiation. Curr Opin Immunol (1994) 1.00
Functional analysis of DNA bending and unwinding by the high mobility group domain of LEF-1. Proc Natl Acad Sci U S A (1997) 0.99
A functional component of the sea urchin H2A gene modulator contains an extended sequence homology to a viral enhancer. Nucleic Acids Res (1983) 0.99
Gene for lymphoid enhancer-binding factor 1 (LEF1) mapped to human chromosome 4 (q23-q25) and mouse chromosome 3 near Egf. Genomics (1991) 0.98
The membrane IgM-associated proteins MB-1 and Ig-beta are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line. Proc Natl Acad Sci U S A (1992) 0.97
Transcriptional regulation of early B-lymphocyte differentiation. Immunol Rev (2000) 0.92
Wnt signaling in lymphopoiesis. Curr Top Microbiol Immunol (2005) 0.92
Nuclear matrix attachment regions confer long-range function upon the immunoglobulin mu enhancer. Cold Spring Harb Symp Quant Biol (1998) 0.90
Gene for a tissue-specific transcriptional activator (EBF or Olf-1), expressed in early B lymphocytes, adipocytes, and olfactory neurons, is located on human chromosome 5, band q34, and proximal mouse chromosome 11. Mamm Genome (1994) 0.89
A mouse mandibular culture model permits the study of neural crest cell migration and tooth development. Int J Dev Biol (1998) 0.85
Control of lymphocyte differentiation by the LEF-1/TCF family of transcription factors. Cold Spring Harb Symp Quant Biol (1999) 0.79
Identification of the regions involved in DNA binding by the mouse PEBP2alpha protein. FEBS Lett (2000) 0.78
Role of enhancer sequences in regulating accessibility of DNA in nuclear chromatin. Cold Spring Harb Symp Quant Biol (1993) 0.76
Studies of immunodifferentiation using transgenic mice. Cold Spring Harb Symp Quant Biol (1985) 0.75
Role of the OCTA site in regulation of IgH chain gene transcription during B cell activation. Int Immunol (1995) 0.75