A and B forms of the androgen receptor are expressed in a variety of human tissues.

PubWeight™: 1.17‹?› | Rank: Top 10%

🔗 View Article (PMID 8809738)

Published in Mol Cell Endocrinol on June 18, 1996

Authors

C M Wilson1, M J McPhaul

Author Affiliations

1: Department of Pharmacology, University of Texas Southwestern Medical Center at Dallas 75235-9041, USA.

Articles citing this

Estrogen and androgen signaling in the pathogenesis of BPH. Nat Rev Urol (2011) 1.52

Correlation of serum androgens with anthropometric and metabolic indices in healthy, nonobese postmenopausal women. J Clin Endocrinol Metab (2010) 1.46

Androgens and estrogens in benign prostatic hyperplasia: past, present and future. Differentiation (2011) 1.42

Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor. J Exp Med (2003) 1.42

Dose-dependent effects of androgens on outcome after focal cerebral ischemia in adult male mice. J Cereb Blood Flow Metab (2009) 1.25

Gender difference in the activity but not expression of estrogen receptors alpha and beta in human lung adenocarcinoma cells. Endocr Relat Cancer (2006) 1.24

Molecular mechanisms regulating glucocorticoid sensitivity and resistance. Mol Cell Endocrinol (2008) 1.19

Gender differences in kidney function. Pflugers Arch (2007) 1.14

Selective androgen receptor modulators in preclinical and clinical development. Nucl Recept Signal (2008) 1.11

Endocrine antecedents of polycystic ovary syndrome in fetal and infant prenatally androgenized female rhesus monkeys. Biol Reprod (2008) 1.10

Sex and gender differences in control of blood pressure. Clin Sci (Lond) (2013) 1.08

Act locally and think globally: intracerebral testosterone implants induce seasonal-like growth of adult avian song control circuits. Proc Natl Acad Sci U S A (2002) 1.04

Attenuated sex steroid receptor expression in fallopian tube of women with ectopic pregnancy. J Clin Endocrinol Metab (2009) 1.03

Contributions of androgen and estrogen to fetal programming of ovarian dysfunction. Reprod Biol Endocrinol (2006) 1.01

Non-genomic effect of testosterone on airway smooth muscle. Br J Pharmacol (2006) 0.93

Androgen and estrogen receptors in the human corpus cavernosum penis: immunohistochemical and cell culture results. World J Urol (2003) 0.90

Androgens in pregnancy: roles in parturition. Hum Reprod Update (2014) 0.89

Bladder cancer and reproductive factors among women in Spain. Cancer Causes Control (2009) 0.89

Dihydrotestosterone activates the MAPK pathway and modulates maximum isometric force through the EGF receptor in isolated intact mouse skeletal muscle fibres. J Physiol (2009) 0.88

Sex steroid signaling: implications for lung diseases. Pharmacol Ther (2015) 0.86

DAX-1 expression in human breast cancer: comparison with estrogen receptors ER-alpha, ER-beta and androgen receptor status. Breast Cancer Res (2004) 0.85

A potential novel spontaneous preterm birth gene, AR, identified by linkage and association analysis of X chromosomal markers. PLoS One (2012) 0.85

Phenotypes, Risk Factors, and Mechanisms of Adult-Onset Asthma. Mediators Inflamm (2015) 0.85

Androgens and prostate cancer. World J Urol (2003) 0.84

Prognostic value of sex-hormone receptor expression in non-muscle-invasive bladder cancer. Yonsei Med J (2014) 0.83

Antitumor effects of bladder cancer-specific adenovirus carrying E1A-androgen receptor in bladder cancer. Gene Ther (2012) 0.82

Testosterone influences renal electrolyte excretion in SHR/y and WKY males. BMC Physiol (2008) 0.80

Beta-carotene affects gene expression in lungs of male and female Bcmo1 (-/-) mice in opposite directions. Cell Mol Life Sci (2010) 0.79

Involvement of the Androgen and Glucocorticoid Receptors in Bladder Cancer. Int J Endocrinol (2015) 0.78

Sex differences in proximal and distal nephron function contribute to the mechanism of idiopathic hypercalcuria in calcium stone formers. Am J Physiol Regul Integr Comp Physiol (2015) 0.77

Moving Beyond the Androgen Receptor (AR): Targeting AR-Interacting Proteins to Treat Prostate Cancer. Horm Cancer (2016) 0.77

The effects of early versus delayed castration targeting androgen on prolonging survival in a mouse model of bladder cancer. Int J Clin Exp Pathol (2015) 0.75

Androgen Receptor Signaling in Bladder Cancer. Cancers (Basel) (2017) 0.75

Sex Differences in Vascular Physiology and Pathophysiology: Estrogen and Androgen Signaling in Health and Disease. Am J Physiol Heart Circ Physiol (2017) 0.75

Direct Involvement of Androgen Receptor in Oxytocin Gene Expression: Possible Relevance for Mood Disorders. Neuropsychopharmacology (2017) 0.75

Articles by these authors

Characterization and expression of a cDNA encoding the human androgen receptor. Proc Natl Acad Sci U S A (1989) 2.49

Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner. Mol Endocrinol (2001) 1.71

Testosterone and 5 alpha-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTV-CAT reporter gene. Mol Cell Endocrinol (1992) 1.60

Cloning, sequencing, and expression of a cDNA encoding rat liver mitochondrial carnitine palmitoyltransferase II. J Biol Chem (1990) 1.42

Androgen receptor gene expression in human prostate carcinoma cell lines. Cancer Res (1990) 1.31

Solubilization of the low density lipoprotein receptor. Proc Natl Acad Sci U S A (1979) 1.23

Definition of the human androgen receptor gene structure permits the identification of mutations that cause androgen resistance: premature termination of the receptor protein at amino acid residue 588 causes complete androgen resistance. Mol Endocrinol (1990) 1.19

Androgen increases androgen receptor protein while decreasing receptor mRNA in LNCaP cells. Mol Cell Endocrinol (1991) 1.18

A single nucleotide substitution introduces a premature termination codon into the androgen receptor gene of a patient with receptor-negative androgen resistance. J Clin Invest (1990) 1.13

Aromatase mRNA in the extragonadal tissues of chickens with the henny-feathering trait is derived from a distinctive promoter structure that contains a segment of a retroviral long terminal repeat. Functional organization of the Sebright, Leghorn, and Campine aromatase genes. J Biol Chem (1991) 1.06

Expression of the human androgen receptor gene utilizes a common promoter in diverse human tissues and cell lines. J Biol Chem (1990) 1.06

Androgens regulate aromatase cytochrome P450 messenger ribonucleic acid in rat brain. Endocrinology (1994) 1.05

Stability of an expanded trinucleotide repeat in the androgen receptor gene in transgenic mice. Nat Genet (1995) 1.05

Amino acid substitutions in the DNA-binding domain of the human androgen receptor are a frequent cause of receptor-binding positive androgen resistance. Mol Endocrinol (1992) 1.03

A and B forms of the androgen receptor are present in human genital skin fibroblasts. Proc Natl Acad Sci U S A (1994) 1.03

RFG (ARA70, ELE1) interacts with the human androgen receptor in a ligand-dependent fashion, but functions only weakly as a coactivator in cotransfection assays. Mol Endocrinol (1999) 1.00

Antipeptide antibodies to two distinct regions of the androgen receptor localize the receptor protein to the nuclei of target cells in the rat and human prostate. Endocrinology (1990) 1.00

Immunocytochemical distribution of aromatase cytochrome P450 in the rat brain using peptide-generated polyclonal antibodies. Endocrinology (1991) 0.97

Mutations of the androgen receptor coding sequence are infrequent in patients with isolated hypospadias. J Clin Endocrinol Metab (1995) 0.96

Biochemical properties of chimeric skeletal and smooth muscle myosin light chain kinases. J Biol Chem (1992) 0.96

Replacement of neutral lipids of low density lipoprotein with esters of long chain unsaturated fatty acids. J Biol Chem (1979) 0.95

A mutation in the DNA-binding domain of the androgen receptor gene causes complete testicular feminization in a patient with receptor-positive androgen resistance. J Clin Invest (1991) 0.94

Complete testicular feminization caused by an amino-terminal truncation of the androgen receptor with downstream initiation. J Clin Invest (1993) 0.94

A steroidogenic factor-1-binding site and cyclic adenosine 3',5'-monophosphate response element-like elements are required for the activity of the rat aromatase promoter in rat Leydig tumor cell lines. Endocrinology (1998) 0.93

The androgen receptor (AR) in syndromes of androgen insensitivity and in prostate cancer. J Steroid Biochem Mol Biol (2001) 0.90

Truncated forms of the androgen receptor are associated with polyglutamine expansion in X-linked spinal and bulbar muscular atrophy. Hum Mol Genet (1998) 0.88

Functional analysis of the human androgen receptor promoter. Mol Cell Endocrinol (1996) 0.88

Transcriptional activation and transient expression of the human androgen receptor. J Steroid Biochem Mol Biol (1996) 0.88

Time-specific androgen blockade with flutamide inhibits testicular descent in the rat. Endocrinology (1991) 0.87

Androgen insensitivity syndrome. Baillieres Clin Endocrinol Metab (1994) 0.86

Amino acid substitutions in the hormone-binding domain of the human androgen receptor alter the stability of the hormone receptor complex. J Clin Invest (1994) 0.86

Immunoreactive androgen receptor expression in subjects with androgen resistance. J Clin Endocrinol Metab (1992) 0.86

Use of the probasin promoter ARR2PB to express Bax in androgen receptor-positive prostate cancer cells. J Natl Cancer Inst (2001) 0.86

Expression and characterization of full-length and partial human androgen receptor fusion proteins. Implications for the production and applications of soluble steroid receptors in Escherichia coli. Mol Cell Endocrinol (1992) 0.85

Localization of the androgen receptor in the developing rat gubernaculum. Endocrinology (1991) 0.84

Androgen resistance associated with a mutation of the androgen receptor at amino acid 772 (Arg----Cys) results from a combination of decreased messenger ribonucleic acid levels and impairment of receptor function. J Clin Endocrinol Metab (1991) 0.84

Identification of genes expressed in the rat prostate that are modulated differently by castration and Finasteride treatment. J Endocrinol (1998) 0.83

Aromatase messenger RNA is derived from the proximal promoter of the aromatase gene in Leydig, Sertoli, and germ cells of the rat testis. Biol Reprod (2001) 0.82

The gene for aromatase (P450arom) in the chicken is located on the long arm of chromosome 1. J Hered (1991) 0.82

Inheritance of the henny feathering trait in the golden Campine chicken: evidence for allelism with the gene that causes henny feathering in the Sebright bantam. J Hered (1990) 0.80

The androgen receptor of the urogenital tract of the fetal rat is regulated by androgen. Mol Cell Endocrinol (1994) 0.80

Expression of aromatase cytochrome P450 in rat H540 Leydig tumor cells. J Steroid Biochem Mol Biol (1998) 0.80

Ovarian aromatase cytochrome P-450 mRNA levels correlate with enzyme activity and serum estradiol levels in anestrous, pregnant and lactating rats. Mol Cell Endocrinol (1992) 0.80

Irradiation selectively inhibits expression from the androgen-dependent Pem homeobox gene promoter in sertoli cells. Endocrinology (2001) 0.79

Functional activities of the A and B forms of the human androgen receptor in response to androgen receptor agonists and antagonists. Mol Endocrinol (1998) 0.79

Inverse relationship between ovarian aromatase cytochrome P450 and 5 alpha-reductase enzyme activities and mRNA levels during the estrous cycle in the rat. J Steroid Biochem Mol Biol (1992) 0.79

Androgen receptor expression in the developing rat prostate is not altered by castration, flutamide, or suppression of the adrenal axis. Endocrinology (1991) 0.79

Expression of mRNA species encoding steroidogenic enzymes in the rat ovary. J Mol Endocrinol (1991) 0.78

Regulation of androgen receptor gene expression by steroids and retinoic acid in human breast-cancer cells. Int J Cancer (1992) 0.78

Brain aromatase cytochrome P-450 messenger RNA levels and enzyme activity during prenatal and perinatal development in the rat. Brain Res Mol Brain Res (1992) 0.78

Androgen receptors containing expanded polyglutamine tracts exhibit progressive toxicity when stably expressed in the neuroblastoma cell line, SH-SY 5Y. Exp Biol Med (Maywood) (2003) 0.78

Regulation of immunoreactive androgen receptor in the adrenal gland of the adult rat. Endocrinology (1996) 0.78

Definition of the elements required for the activity of the rat aromatase promoter in steroidogenic cell lines. J Steroid Biochem Mol Biol (1997) 0.77

Sebright and Campine chickens express aromatase P-450 messenger RNA inappropriately in extraglandular tissues and in skin fibroblasts. Mol Endocrinol (1990) 0.77

Development and characterization of a mouse prostate adenocarcinoma cell line: ductal formation determined by extracellular matrix. Prostate (1998) 0.77

Flutamide-induced testicular undescent in the rat is associated with alterations in genitofemoral nerve morphology. J Urol (1994) 0.76

Recent studies of the androgen receptor: new insights into old questions. Mol Cell Endocrinol (1990) 0.76

Virilization of the female spotted hyena cannot be explained by alterations in the amino acid sequence of the androgen receptor (AR). Mol Cell Endocrinol (2002) 0.76

The structure of cDNA clones encoding the aromatase P-450 isolated from a rat Leydig cell tumor line demonstrates differential processing of aromatase mRNA in rat ovary and a neoplastic cell line. Mol Cell Endocrinol (1990) 0.76

Decreased levels of the androgen receptor in the mature rat phallus are associated with decreased levels of androgen receptor messenger ribonucleic acid. Endocrinology (1991) 0.76

Characterization of aromatase cytochrome P-450 mRNA in rat perinatal brain, ovary and a Leydig tumor cell line: evidence for the existence of brain specific aromatase transcripts. Endocrine (1995) 0.76

Androgen receptor levels in the rat penis are controlled differently in distinctive cell types. Endocrinology (1991) 0.75

Cloning and partial sequence of the rabbit androgen receptor: expression in fetal urogenital tissues. J Androl (1995) 0.75

Hormone-binding and solubility properties of fusion proteins containing the ligand-binding domain of the human androgen receptor. J Steroid Biochem Mol Biol (1996) 0.75

Expression of the human androgen receptor in eukaryotic cells using a recombinant adenovirus vector yields high levels of the soluble, functional receptor protein. J Mol Endocrinol (2001) 0.75

[Clinical and molecular basis of androgen resistance]. Recenti Prog Med (1992) 0.75

Reversal of flutamide-induced cryptorchidism by prenatal time-specific androgens. Endocrinology (1992) 0.75

An androgenic affinity ligand covalently binds to cytosolic aldehyde dehydrogenase from human genital skin fibroblasts. Mol Cell Endocrinol (1993) 0.75

Molecular basis of androgen resistance. J Endocrinol Invest (1992) 0.75