Published in Endocrinology on August 01, 1977
Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects. Proc Natl Acad Sci U S A (1989) 1.33
Serum insulin-like growth factor-I in diabetic retinopathy. Mol Vis (2011) 0.89
Dual control of cell growth by somatomedins and platelet-derived growth factor. Proc Natl Acad Sci U S A (1979) 4.32
Nutritional regulation of the insulin-like growth factors. Endocr Rev (1994) 3.18
Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci U S A (1984) 3.13
Clinical uses of insulin-like growth factor I. Ann Intern Med (1994) 2.93
Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor. J Biol Chem (1983) 2.55
Monoclonal antibodies to receptors for insulin and somatomedin-C. J Biol Chem (1983) 2.53
Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay. J Clin Invest (1977) 2.46
Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds. Dev Biol (1996) 2.15
Evidence that somatomedin is synthesized by multiple tissues in the fetus. Dev Biol (1980) 2.11
Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus. Science (1987) 2.01
Social approach in genetically engineered mouse lines relevant to autism. Genes Brain Behav (2008) 1.94
Hormonal control of immunoreactive somatomedin production by cultured human fibroblasts. J Clin Invest (1981) 1.92
Purification of somatomedin-C from human plasma: chemical and biological properties, partial sequence analysis, and relationship to other somatomedins. Biochemistry (1980) 1.86
Behavior change after growth hormone treatment of children with short stature. J Pediatr (1998) 1.82
Nucleotide sequence analysis of a cDNA encoding human ubiquitin reveals that ubiquitin is synthesized as a precursor. J Biol Chem (1985) 1.77
The somatomedins: a family of insulinlike hormones under growth hormone control. Recent Prog Horm Res (1974) 1.76
Impaired growth and fertility of cAMP-specific phosphodiesterase PDE4D-deficient mice. Proc Natl Acad Sci U S A (1999) 1.73
Growth enhancement of transgenic mice expressing human insulin-like growth factor I. Endocrinology (1988) 1.72
Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development. J Neurosci (2000) 1.68
Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance. J Biol Chem (2001) 1.67
Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues. J Biol Chem (1986) 1.67
Evidence from monoclonal antibody studies that insulin stimulates deoxyribonucleic acid synthesis through the type I somatomedin receptor. J Clin Endocrinol Metab (1985) 1.49
Explorations of the insulinlike and growth-promoting properties of somatomedin by membrane receptor assays. Adv Metab Disord (1975) 1.49
Induction of immunoreactive somatomedin C human serum by growth hormone: dose-response relationships and effect on chromatographic profiles. J Clin Endocrinol Metab (1980) 1.48
Insulin-like growth factors as intraovarian regulators of granulosa cell growth and function. Endocr Rev (1985) 1.47
Effects of caloric or protein restriction on insulin-like growth factor-I (IGF-I) and IGF-binding proteins in children and adults. J Clin Endocrinol Metab (1995) 1.47
Evidence for a functional role of endogenously produced somatomedinlike peptides in the regulation of DNA synthesis in cultured human fibroblasts and porcine smooth muscle cells. J Clin Invest (1985) 1.43
Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS. J Pediatr (1993) 1.43
Homozygous nonsense mutation in the insulin receptor gene of a patient with severe congenital insulin resistance: leprechaunism and the role of the insulin-like growth factor receptor. Clin Endocrinol (Oxf) (1996) 1.42
Sequence analysis of somatomedin-C: confirmation of identity with insulin-like growth factor I. Endocrinology (1983) 1.40
Somatomedin-C receptors and growth effects in human breast cells maintained in long-term tissue culture. Cancer Res (1984) 1.40
Stimulation of statural growth by recombinant insulin-like growth factor I in a child with growth hormone insensitivity syndrome (Laron type) J Pediatr (1992) 1.37
Epidermal growth factor (EGF) is required only during the traverse of early G1 in PDGF stimulated density-arrested BALB/c-3T3 cells. Exp Cell Res (1983) 1.36
Academic achievement and psychological adjustment in short children. The National Cooperative Growth Study. J Dev Behav Pediatr (1994) 1.34
Evidence from radioligand assays that somatomedin-C and insulin-like growth factor-I are similar to each other and different from other somatomedins. J Clin Endocrinol Metab (1980) 1.31
In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice. J Neurosci (1995) 1.30
Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C. Proc Natl Acad Sci U S A (1984) 1.30
Cultured fibroblast monolayers secrete a protein that alters the cellular binding of somatomedin-C/insulinlike growth factor I. J Clin Invest (1986) 1.27
Insulin-like growth factor I/somatomedin C: a potent inducer of oligodendrocyte development. Proc Natl Acad Sci U S A (1986) 1.27
Neonatal and infantile hypoglycemia due to insulin excess: new aspects of diagnosis and surgical management. Ann Surg (1977) 1.26
The subunit structure of alpha-acetohydroxyacid isomeroreductase from Salmonella typhimurium. J Biol Chem (1975) 1.26
Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination. J Neurosci (2000) 1.26
Expression of somatomedin/insulin-like growth factor messenger ribonucleic acids in the human fetus: identification, characterization, and tissue distribution. J Clin Endocrinol Metab (1988) 1.25
Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase deficiency. N Engl J Med (2000) 1.24
Affinity-labeled plasma somatomedin-C/insulinlike growth factor I binding proteins. Evidence of growth hormone dependence and subunit structure. J Clin Invest (1985) 1.23
Leprechaunism: studies of the relationship among hyperinsulinism, insulin resistance, and growth retardation. J Clin Endocrinol Metab (1979) 1.23
Characterization of the insulin and somatomedin-C receptors in human placental cell membranes. J Clin Endocrinol Metab (1974) 1.22
In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: evidence that IGF-I increases proliferation of granule cell progenitors. Brain Res Dev Brain Res (1996) 1.20
Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor. J Biol Chem (1998) 1.19
Further purification and characterization of sulfation factor and thymidine factor from acromegalic plasma. J Clin Endocrinol Metab (1971) 1.18
Competitive binding of somatomedin to the insulin receptors of adipocytes, chondrocytes, and liver membranes. Proc Natl Acad Sci U S A (1972) 1.18
Structural similarities between human receptors for somatomedin C and insulin: analysis by affinity labeling. Biochemistry (1981) 1.17
The type II insulin-like growth factor receptor does not mediate deoxyribonucleic acid synthesis in human fibroblasts. J Clin Endocrinol Metab (1987) 1.17
Nutritional regulation of IGF-I and IGF binding proteins. Annu Rev Nutr (1991) 1.17
Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia. J Biol Chem (1996) 1.17
Dietary components that regulate serum somatomedin-C concentrations in humans. J Clin Invest (1983) 1.16
Caloric restriction and 7,12-dimethylbenz(a)anthracene-induced mammary tumor growth in rats: alterations in circulating insulin, insulin-like growth factors I and II, and epidermal growth factor. Cancer Res (1989) 1.15
Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-I. Proc Natl Acad Sci U S A (1991) 1.15
Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells. Cancer Res (1990) 1.15
Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv). Cancer Res (1992) 1.14
Enhanced growth of small bowel in transgenic mice expressing human insulin-like growth factor I. Gastroenterology (1997) 1.14
Further evidence of a target organ defect in the syndrome of testicular feminization. J Clin Endocrinol Metab (1966) 1.14
The somatomedin C binding protein: evidence for a heterologous subunit structure. J Clin Endocrinol Metab (1980) 1.13
Evaluation of acromegaly by radioimmunoassay of somatomedin-C. N Engl J Med (1979) 1.13
Regulation of insulin-like growth factor-I in starvation and injury. Nutr Rev (1999) 1.12
Growth hormone levels during sleep in normal and growth hormone deficient children. Pediatrics (1971) 1.11
Expression of insulin-like growth factor-I (IGF-I) and IGF-binding proteins during adipogenesis. Endocrinology (1994) 1.11
Metastatic but not primary melanoma cell lines grow in vitro independently of exogenous growth factors. Int J Cancer (1987) 1.11
Elevated serum prolactin levels after pituitary-stalk section in man. N Engl J Med (1971) 1.11
Clinical studies with recombinant-DNA-derived methionyl human growth hormone in growth hormone deficient children. Lancet (1986) 1.10
Sequential addition of platelet factor and plasma to BALB/c 3T3 fibroblast cultures stimulates somatomedin-C binding early in cell cycle. Proc Natl Acad Sci U S A (1980) 1.10
Regulation of components of the ubiquitin system by insulin-like growth factor I and growth hormone in skeletal muscle of rats made catabolic with dexamethasone. Endocrinology (1999) 1.10
Relation of kidney tissue somatomedin-C/insulin-like growth factor I to postnephrectomy renal growth in the rat. Endocrinology (1985) 1.09
Reduction of plasma immunoreactive somatomedin C during fasting in humans. J Clin Endocrinol Metab (1981) 1.08
Identification of somatomedin/insulin-like growth factor immunoreactive cells in the human fetus. Pediatr Res (1987) 1.07
Interferon-gamma protects against cuprizone-induced demyelination. Mol Cell Neurosci (2000) 1.07
Insulin-like growth factor-I binds selectively to human peripheral blood monocytes and B-lymphocytes. J Clin Endocrinol Metab (1991) 1.07
Biphasic concentration dependency of stimulation of myoblast differentiation by somatomedins. Am J Physiol (1986) 1.06