Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research.

PubWeight™: 5.65‹?› | Rank: Top 1%

🔗 View Article (PMID 8874455)

Published in Lancet on October 19, 1996

Articles citing this

(truncated to the top 100)

Ethical debate. Truth, the first casualty. Deadly charades. BMJ (1998) 4.02

RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. Int J Radiat Oncol Biol Phys (2012) 2.12

Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin. J Clin Oncol (2012) 1.84

The differential diagnosis and interdisciplinary treatment of anal carcinoma. Dtsch Arztebl Int (2015) 1.62

Synchronous chemoradiation for squamous carcinomas. BMJ (2001) 1.61

Optimal organ-sparing intensity-modulated radiation therapy (IMRT) regimen for the treatment of locally advanced anal canal carcinoma: a comparison of conventional and IMRT plans. Radiat Oncol (2007) 1.60

Fluorine (19F) MRS and MRI in biomedicine. NMR Biomed (2010) 1.60

Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I). Br J Cancer (2010) 1.57

Penile cancer: current therapy and future directions. Ann Oncol (2013) 1.54

Neoadjuvant paclitaxel, ifosfamide, and cisplatin chemotherapy for metastatic penile cancer: a phase II study. J Clin Oncol (2010) 1.49

Squamous cell cancer of the rectum. World J Gastroenterol (2009) 1.43

5-Fluorouracil: forty-plus and still ticking. A review of its preclinical and clinical development. Invest New Drugs (2000) 1.40

Gastrointestinal complications of pelvic radiotherapy: are they of any importance? Gut (2005) 1.37

Neoplasms of anal canal and perianal skin. Clin Colon Rectal Surg (2011) 1.28

Plan comparison of volumetric-modulated arc therapy (RapidArc) and conventional intensity-modulated radiation therapy (IMRT) in anal canal cancer. Radiat Oncol (2010) 1.25

Definitive chemoradiation in patients with inoperable oesophageal carcinoma. Br J Cancer (2004) 1.13

Prognostic factors derived from a prospective database dictate clinical biology of anal cancer: the intergroup trial (RTOG 98-11). Cancer (2010) 1.09

Anal squamous cell carcinoma: an evolution in disease and management. World J Gastroenterol (2014) 1.03

Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08. Int J Radiat Oncol Biol Phys (2008) 1.02

Multimodality therapy in penile cancer: when and which treatments? World J Urol (2008) 0.99

Reconstruction of the perineum following anorectal cancer excision. Int J Colorectal Dis (2008) 0.99

Role of nutritional intervention in patients treated with radiotherapy for pelvic malignancy. Br J Cancer (2004) 0.97

Intensity-Modulated Radiation Therapy vs. 3D Conformal Radiation Therapy for Squamous Cell Carcinoma of the Anal Canal. Gastrointest Cancer Res (2013) 0.97

Buschke-Löwenstein tumor with squamous cell carcinoma treated with chemo-radiation therapy and local surgical excision: report of three cases. World J Surg Oncol (2013) 0.95

NCI-RTOG translational program strategic guidelines for the early-stage development of radiosensitizers. J Natl Cancer Inst (2012) 0.94

IMRT for locally advanced anal cancer: clinical experience of the Montpellier Cancer Center. Radiat Oncol (2012) 0.93

Squamous cell carcinoma of the anus-an opportunistic cancer in HIV-positive male homosexuals. World J Gastroenterol (2011) 0.92

Prognostic biomarkers in squamous cell carcinoma of the anus: a systematic review. Br J Cancer (2010) 0.90

Phase II study of mitomycin-C, adriamycin, cisplatin (MAP) and Bleomycin-CCNU in patients with advanced cancer of the anal canal: An eastern cooperative oncology group study E7282. Invest New Drugs (2006) 0.89

Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial. Int J Radiat Oncol Biol Phys (2013) 0.89

The impact of 18-fluorodeoxyglucose positron emission tomography on the staging, management and outcome of anal cancer. Br J Cancer (2009) 0.88

Quality of life and tumor control after short split-course chemoradiation for anal canal carcinoma. Radiat Oncol (2010) 0.88

Gene expression reveals two distinct groups of anal carcinomas with clinical implications. Br J Cancer (2008) 0.87

Premalignant lesions of the anal canal and squamous cell carcinoma of the anal canal. Clin Colon Rectal Surg (2011) 0.87

Stopping clinical trials early for futility: retrospective analysis of several randomised clinical studies. Br J Cancer (2012) 0.87

Quality of life outcomes in patients with anal cancer after combined radiochemotherapy. Strahlenther Onkol (2011) 0.87

Long-term results of a phase II study of synchronous chemoradiotherapy in advanced muscle invasive bladder cancer. Br J Cancer (2004) 0.86

Prognostic factors for squamous cell cancer of the anal canal. Gastrointest Cancer Res (2008) 0.86

Multimodal therapy of anal cancer added by new endosonographic-guided brachytherapy. Surg Endosc (2006) 0.86

Can the radiation dose to CT-enlarged but FDG-PET-negative inguinal lymph nodes in anal cancer be reduced? Strahlenther Onkol (2009) 0.86

Higher radiation dose with a shorter treatment duration improves outcome for locally advanced carcinoma of anal canal. World J Gastroenterol (2007) 0.86

Efficacy and toxicity of chemoradiation in patients with anal cancer--a retrospective analysis. Radiat Oncol (2014) 0.86

Combined-modality treatment for anal cancer: current strategies and future directions. Strahlenther Onkol (2010) 0.86

Radiation therapy of anal canal cancer: from conformal therapy to volumetric modulated arc therapy. BMC Cancer (2014) 0.85

Effective treatment of anal cancer in the elderly with low-dose chemoradiotherapy. Br J Cancer (2005) 0.84

Multiparametric MRI as an outcome predictor for anal canal cancer managed with chemoradiotherapy. BMC Cancer (2015) 0.83

Does gap-free intensity modulated chemoradiation therapy provide a greater clinical benefit than 3D conformal chemoradiation in patients with anal cancer? Radiat Oncol (2012) 0.82

Local tumor control and toxicity in HIV-associated anal carcinoma treated with radiotherapy in the era of antiretroviral therapy. Radiat Oncol (2006) 0.82

Interstitial high-dose rate brachytherapy as boost for anal canal cancer. Radiat Oncol (2014) 0.82

Chemoradiotherapy with or without consolidation chemotherapy using cisplatin and 5-fluorouracil in anal squamous cell carcinoma: long-term results in 31 patients. BMC Cancer (2008) 0.82

Metastatic squamous cell carcinoma of the anus: time for a shift in the treatment paradigm? ISRN Oncol (2012) 0.81

Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option. Br J Cancer (2014) 0.81

Anal canal carcinoma: experience from a single Korean institution. Yonsei Med J (2007) 0.81

The prognostic value of HPV status and p16 expression in patients with carcinoma of the anal canal. PLoS One (2014) 0.81

Impact of bone marrow radiation dose on acute hematologic toxicity in cervical cancer: principal component analysis on high dimensional data. Int J Radiat Oncol Biol Phys (2010) 0.81

Cyclin D1, cyclin E, and p21 have no apparent prognostic value in anal carcinomas treated by radiotherapy with or without chemotherapy. Br J Cancer (2004) 0.81

Development of cerebral metastasis after medical and surgical treatment of anal squamous cell carcinoma. Case Rep Oncol Med (2012) 0.80

FDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma. Radiat Oncol (2010) 0.80

Chemoradiotherapy in squamous cell carcinoma of the anal canal: a single institution experience. Radiat Oncol J (2013) 0.80

Combined radiotherapy and chemotherapy for anal cancer. EORTC Radiotherapy and Gastrointestinal Cooperative Groups. Lancet (1997) 0.80

Human papilloma virus and squamous cell carcinoma of the anus. Clin Med Insights Oncol (2014) 0.79

Management of persistent anal canal carcinoma after combined-modality therapy: a clinical review. Radiat Oncol (2014) 0.79

Technical aspects of radiation therapy for anal cancer. J Gastrointest Oncol (2014) 0.79

HIV- positive anal cancer: an update for the clinician. J Gastrointest Oncol (2010) 0.79

Radical chemoradiotherapy for urethral squamous cell carcinoma: two case reports and a review of the literature. Case Rep Urol (2013) 0.79

Anal canal cancer treatment: practical limitations of routine prescription of concurrent chemotherapy and radiotherapy. Br J Cancer (2003) 0.79

Concurrent chemoradiotherapy for squamous cell carcinoma of the anus using a shrinking field radiotherapy technique without a boost. Br J Cancer (2003) 0.79

A rare case of anal tumor: Anal carcinosarcoma. World J Gastrointest Oncol (2010) 0.78

Sphincter preservation in anal cancer: a brief review. Saudi J Gastroenterol (2013) 0.78

Anal cancer treated with radio-chemotherapy: correlation between length of treatment interruption and outcome. Int J Colorectal Dis (2009) 0.78

Surgical salvage therapy of anal cancer. World J Gastroenterol (2004) 0.78

Clinical experience of SIB-IMRT in anal cancer and selective literature review. Radiat Oncol (2014) 0.78

Chemoradiation with capecitabine and mitomycin-C for stage I-III anal squamous cell carcinoma. Radiat Oncol (2014) 0.78

Concurrent cisplatin, continuous infusion fluorouracil and radiotherapy followed by tailored consolidation treatment in non metastatic anal squamous cell carcinoma. BMC Cancer (2011) 0.78

One compared with two cycles of mitomycin C in chemoradiotherapy for anal cancer: analysis of outcomes and toxicity. Curr Oncol (2014) 0.78

Early squamous cell carcinoma of the anal canal resected by endoscopic submucosal dissection. Case Rep Gastroenterol (2015) 0.78

Bladder Sparing Approaches for Muscle-Invasive Bladder Cancers. Curr Treat Options Oncol (2016) 0.77

MITHRA - multiparametric MR/CT image adapted brachytherapy (MR/CT-IABT) in anal canal cancer: a feasibility study. J Contemp Brachytherapy (2015) 0.77

Chemoradiation therapy with S-1 for primary squamous cell carcinoma of the rectum: report of three cases. Surg Case Rep (2015) 0.77

Should cisplatin be avoided in the treatment of locally advanced squamous cell carcinoma of the anal canal? Nat Clin Pract Gastroenterol Hepatol (2008) 0.76

Postoperative versus definitive chemoradiation in early-stage anal cancer. Results of a matched-pair analysis. Strahlenther Onkol (2012) 0.76

Epidermoid cancers of the anal canal: current treatment. Clin Colon Rectal Surg (2009) 0.76

Anal canal carcinoma treatment results: the experience of a single institution. Ann Saudi Med (2011) 0.76

Urological cancer: Chemoradiation superior in muscle-invasive bladder cancer. Nat Rev Clin Oncol (2012) 0.76

Long-term follow-up of a Phase II trial of high-dose radiation with concurrent 5-fluorouracil and cisplatin in patients with anal cancer (ECOG E4292). Int J Radiat Oncol Biol Phys (2011) 0.76

Long-term outcomes of chemoradiation for anal cancer patients. Yonsei Med J (2013) 0.76

Clinical trials in the management of anal cancer. Clin Colon Rectal Surg (2009) 0.75

New approach to anal cancer: individualized therapy based on sentinel lymph node biopsy. World J Gastroenterol (2012) 0.75

Concomitant radiotherapy and chemotherapy for high-risk nonmelanoma skin carcinomas of the head and neck. Int J Surg Oncol (2011) 0.75

[RCT with 5-FU and mitomycin C with 28 fractions of 1.8 Gy external radiotherapy remains standard treatment of squamous-cell carcinoma of the anus]. Strahlenther Onkol (2013) 0.75

Chemo-radiation with or without mandatory split in anal carcinoma: experiences of two institutions and review of the literature. Radiat Oncol (2010) 0.75

Management of two cases of recurrent anal carcinoma. Case Rep Oncol (2013) 0.75

[Organ-sparing chemoradiotherapy: a viable alternative to initial cystectomy for patients with muscle-invasive bladder cancer]. Strahlenther Onkol (2012) 0.75

Can radiobiological parameters derived from squamous cell carcinoma of the head and neck be used to predict local control in anal cancer treated with chemoradiation? Br J Radiol (2013) 0.75

A case of perianal mucinous adenocarcinoma arising from an anorectal fistula successfully resected after preoperative radiotherapy. Case Rep Gastroenterol (2013) 0.75

Carcinoma arising within an anal gland. BMJ Case Rep (2011) 0.75

Squamous-cell carcinoma of the anus: progress in radiotherapy treatment. Nat Rev Clin Oncol (2016) 0.75

Intensity-modulated radiotherapy for squamous cell carcinoma of the anal canal: efficacy of a low daily dose to clinically negative regions. Radiat Oncol (2011) 0.75

Successful treatment of anal carcinoma with Paclitaxel, Cisplatin, and radiotherapy in a patient who developed a coronary syndrome from 5-fu. Gastrointest Cancer Res (2012) 0.75

[Cause-specific colostomy rates after radiotherapy for anal cancer: a Danish multicentre cohort study]. Strahlenther Onkol (2012) 0.75