G Zürcher

Author PubWeight™ 28.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ESPEN Guidelines on Enteral Nutrition: Non-surgical oncology. Clin Nutr 2006 2.89
2 Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase. Mol Cell Biol 1991 2.47
3 Mutation position and type of substitution in the beta-subunit of the RNA polymerase influence in-vitro activity of rifamycins in rifampicin-resistant Mycobacterium tuberculosis. J Antimicrob Chemother 1995 2.22
4 Expression of two novel eph-related receptor protein tyrosine kinases in mammary gland development and carcinogenesis. Oncogene 1994 1.51
5 Pharmacokinetic-pharmacodynamic interaction between the COMT inhibitor tolcapone and single-dose levodopa. Br J Clin Pharmacol 1995 1.09
6 Integrated pharmacokinetics and pharmacodynamics of the novel catechol-O-methyltransferase inhibitor tolcapone during first administration to humans. Clin Pharmacol Ther 1995 1.06
7 Rapid and sensitive single-step radiochemical assay for catechol-O-methyltransferase. J Neurochem 1982 1.06
8 On tyramine, food, beverages and the reversible MAO inhibitor moclobemide. J Neural Transm Suppl 1988 0.97
9 Multiple-dose clinical pharmacology of the catechol-O-methyl-transferase inhibitor tolcapone in elderly subjects. Eur J Clin Pharmacol 1996 0.92
10 Characterization of a novel murine testis-specific serine/threonine kinase. Gene 1994 0.92
11 Optimizing levodopa pharmacokinetics with multiple tolcapone doses in the elderly. Clin Pharmacol Ther 1997 0.92
12 Bioavailability of L-dopa after Madopar HBS administration in healthy volunteers. Eur Neurol 1987 0.92
13 Molecular characterization of the murine syk protein tyrosine kinase cDNA, transcripts and protein. Biochem Biophys Res Commun 1995 0.90
14 Pharmacokinetic-pharmacodynamic interactions between two selective monoamine oxidase inhibitors: moclobemide and selegiline. Clin Neuropharmacol 1996 0.89
15 Structure-based design, synthesis, and in vitro evaluation of bisubstrate inhibitors for catechol O-methyltransferase (COMT). Chemistry 2000 0.87
16 iyk, a novel intracellular protein tyrosine kinase differentially expressed in the mouse mammary gland and intestine. Biochem Biophys Res Commun 1995 0.86
17 The effect of COMT inhibition by tolcapone on tolerability and pharmacokinetics of different levodopa/benserazide formulations. Eur Neurol 1997 0.86
18 Pharmacodynamics of benserazide assessed by its effects on endogenous and exogenous levodopa pharmacokinetics. Br J Clin Pharmacol 1997 0.85
19 Intestinal absorption of levodopa in man. Eur J Clin Pharmacol 1983 0.85
20 Expression of functional membrane-bound and soluble catechol-O-methyltransferase in Escherichia coli and a mammalian cell line. J Neurochem 1992 0.83
21 Pharmacokinetics and pharmacodynamics after oral and intravenous administration of tolcapone, a novel adjunct to Parkinson's disease therapy. Eur J Clin Pharmacol 1998 0.83
22 Effects of tolcapone, a novel catechol-O-methyltransferase inhibitor, on striatal metabolism of L-dopa and dopamine in rats. Eur J Pharmacol 1995 0.83
23 Simultaneous determination of histamine and N alpha-methylhistamine in biological samples by an improved enzymatic single isotope assay. Agents Actions 1985 0.82
24 Inhibition of decarboxylase and levels of dopa and 3-O-methyldopa: a comparative study of benserazide versus carbidopa in rodents and of Madopar standard versus Madopar HBS in volunteers. Eur Neurol 1987 0.82
25 Investigation of a correlation between monoamine oxidase B and catechol-O-methyltransferase activity in human blood cells. Eur J Pharm Sci 2000 0.81
26 Radioenzymatic assay of femtomole concentrations of DOPA in tissues and body fluids. J Neurochem 1979 0.78
27 Immunoaffinity purification and partial amino acid sequence analysis of catechol-O-methyltransferase from pig liver. Biochim Biophys Acta 1991 0.76
28 Monoclonal antibodies recognizing both soluble and membrane bound catechol-O-methyltransferase. J Neural Transm Suppl 1990 0.75
29 Tyramine content of preserved and fermented foods or condiments of Far Eastern cuisine. Psychopharmacology (Berl) 1992 0.75
30 Mosé Da Prada and the discovery of tolcapone. J Neural Transm Suppl 1998 0.75
31 Tyrosine kinases: from viral oncogenes to developmental regulators. Behring Inst Mitt 1991 0.75
32 Conversion of the neurotoxic precursor 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine into its pyridinium metabolite by human platelet monoamine oxidase type B. Neurosci Lett 1985 0.75
33 Clinical, pharmacokinetic, and pharmacodynamic effects of tolcapone withdrawal in levodopa-treated patients with parkinsonism. Clin Neuropharmacol 2000 0.75