C M Clark

Author PubWeight™ 118.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome. JAMA 2001 5.13
2 Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 1997 3.77
3 Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment. Neurobiol Aging 2005 3.00
4 High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype. Arch Neurol 1998 2.77
5 CSF biomarkers in frontotemporal lobar degeneration with known pathology. Neurology 2008 2.43
6 Individual patient diagnosis of AD and FTD via high-dimensional pattern classification of MRI. Neuroimage 2008 2.36
7 Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease. Neurology 2000 2.27
8 Rate of progression differs in frontotemporal dementia and Alzheimer disease. Neurology 2005 2.18
9 Cognitive and motor assessment in autopsy-proven corticobasal degeneration. Neurology 2007 2.09
10 Who provides patients with drug information? Br Med J (Clin Res Ed) 1987 2.04
11 Basal insulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE 901) and NPH insulin. Diabetes Care 2001 1.94
12 A systematic review of treatments for severe psoriasis. Health Technol Assess 2000 1.93
13 Novel CSF biomarkers for frontotemporal lobar degenerations. Neurology 2010 1.89
14 Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity. Ann Neurol 2000 1.79
15 Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia. Ann Neurol 2001 1.75
16 Enhanced brain levels of 8,12-iso-iPF2alpha-VI differentiate AD from frontotemporal dementia. Neurology 2003 1.66
17 The diabetes education study: a controlled trial of the effects of diabetes patient education. Diabetes Care 1986 1.63
18 Primary care physicians' practice patterns and diabetic retinopathy. Current levels of care. Arch Fam Med 1997 1.62
19 Genetic linkage studies in Alzheimer's disease families. Exp Neurol 1988 1.57
20 The severe impairment battery: concurrent validity and the assessment of longitudinal change in Alzheimer's disease. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 1997 1.53
21 Sherpa brain glucose metabolism and defense adaptations against chronic hypoxia. J Appl Physiol (1985) 1996 1.47
22 Tau in cerebrospinal fluid: a potential diagnostic marker in Alzheimer's disease. Ann Neurol 1995 1.46
23 Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Proc Natl Acad Sci U S A 2009 1.39
24 Corticobasal syndrome and primary progressive aphasia as manifestations of LRRK2 gene mutations. Neurology 2007 1.33
25 Linkage analysis of familial Alzheimer disease, using chromosome 21 markers. Am J Hum Genet 1991 1.26
26 The relationship between caregivers' global ratings of Alzheimer's disease patients' quality of life, disease severity, and the caregiving experience. J Am Geriatr Soc 2001 1.25
27 Cerebrospinal fluid tau levels in neurodegenerative diseases with distinct tau-related pathology. Biochem Biophys Res Commun 1997 1.24
28 Ratings of personality change in patients being evaluated for memory disorders. Alzheimer Dis Assoc Disord 1991 1.18
29 Evaluation of the use of programmed instruction for patients maintained on Warfarin therapy. Am J Public Health 1972 1.18
30 Mandatory assessment of patients over 75. BMJ 1991 1.16
31 Patterns of referral and examination for retinopathy in pregnant women with diabetes by primary care physicians. Ophthalmic Epidemiol 1995 1.13
32 The brain at high altitude: hypometabolism as a defense against chronic hypoxia? J Cereb Blood Flow Metab 1994 1.09
33 Caregivers' preferences for the treatment of patients with Alzheimer's disease. Neurology 2000 1.02
34 The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part VI. Family history assessment: a multicenter study of first-degree relatives of Alzheimer's disease probands and nondemented spouse controls. Neurology 1994 1.02
35 Inhaled foreign bodies in children. Med J Aust 1983 1.01
36 Comparison of positron emission tomography, cognition, and brain volume in Alzheimer's disease with and without severe abnormalities of white matter. J Neurol Neurosurg Psychiatry 1996 1.01
37 31P magnetic resonance spectroscopy of the Sherpa heart: a phosphocreatine/adenosine triphosphate signature of metabolic defense against hypobaric hypoxia. Proc Natl Acad Sci U S A 1996 0.99
38 Enhanced cardiac metabolism of plasma glucose in high-altitude natives: adaptation against chronic hypoxia. J Appl Physiol (1985) 1995 0.99
39 Sodium MR imaging detection of mild Alzheimer disease: preliminary study. AJNR Am J Neuroradiol 2009 0.99
40 Demonstration of a defect in the formation of adenosine 3',5'-monophosphate in vasopressin-resistant diabetes insipidus. Pediatr Res 1974 0.98
41 Clinical evaluation of global change in Alzheimer's disease: identifying consensus. J Geriatr Psychiatry Neurol 1996 0.98
42 Factors associated with survival probability in autopsy-proven frontotemporal lobar degeneration. J Neurol Neurosurg Psychiatry 2007 0.97
43 The National Diabetes Education Program, changing the way diabetes is treated: comprehensive diabetes care. Diabetes Care 2001 0.96
44 Evidence for delayed development of the glucagon receptor of adenylate cyclase in the fetal and neonatal rat heart. J Clin Invest 1973 0.94
45 Chronic donepezil treatment is associated with slowed cognitive decline in Alzheimer's disease. Dement Geriatr Cogn Disord 2001 0.94
46 Quantitative neurohistological features of frontotemporal degeneration. Neurobiol Aging 2001 0.92
47 Depletion of proteins of phasic and tonic muscles in tumour-bearing rats. Eur J Cancer 1971 0.91
48 Correlational methods for determining regional coupling of cerebral glucose metabolism: a pilot study. Biol Psychiatry 1984 0.91
49 A videotaped CIBIC for dementia patients: validity and reliability in a simulated clinical trial. Neurology 2002 0.91
50 Serum insulin and somatomedin levels in the tumour-bearing rat. Eur J Cancer 1975 0.90
51 Effects of dibutyryl cyclic adenosine 3',5'-monophosphate and parathyroid extract on calcium and phosphorus metabolism in hypoparathyroidism and pseudohypoparathyroidism. J Clin Invest 1972 0.90
52 Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease. Neurobiol Aging 2010 0.89
53 Influence of lamotrigine on progression of early Huntington disease: a randomized clinical trial. Neurology 1999 0.89
54 Melatonin suppression in bipolar and unipolar mood disorders. Psychiatry Res 1990 0.89
55 The Diabetes Education Study: a controlled trial of the effects of intensive instruction of internal medicine residents on the management of diabetes mellitus. J Gen Intern Med 1988 0.88
56 Role of lipolytic and glucocorticoid hormones in the development of diabetic ketosis. Diabetes 1972 0.88
57 Carbohydrate metabolism in the isolated fetal rat heart. Am J Physiol 1971 0.86
58 The National Diabetes Education Program: changing the way diabetes is treated. Ann Intern Med 1999 0.85
59 Clinical trials in Alzheimer disease: debate on the use of placebo controls. Alzheimer Dis Assoc Disord 1999 0.82
60 Age-related changes in insulin receptor regulation in liver membranes from Zucker fatty rats. Endocrinology 1982 0.82
61 Characterization of glucose metabolism in the isolated rat heart during fetal and early neonatal development. Diabetes 1973 0.82
62 Strategies for improving the postmortem neuropathological diagnosis of Alzheimer's disease. Neurobiol Aging 1997 0.81
63 Effects of exogenous insulin on the rate of fatty acid synthesis and glucose C-14 utilization in the twenty-day rat fetus. Diabetes 1968 0.81
64 Cortical glucose metabolism in Parkinson's and Alzheimer's disease. J Neurosci Res 1990 0.81
65 Care of diabetic pregnant women by primary-care physicians. Reported strategies for managing pregestational and gestational diabetes. Diabetes Care 1992 0.80
66 Effects on regional brain metabolism of high-altitude hypoxia: a study of six US marines. Am J Physiol 1999 0.80
67 Comparison of centrally mediated hypotensive action of methyldopa and DOPA in cats. Arch Int Pharmacodyn Ther 1973 0.79
68 Effects of somatostatin on the hepatic adenylate cyclase system in the rat. Endocrinology 1977 0.79
69 Leucine metabolism in skeletal muscle of the tumour-bearing rat. Eur J Cancer 1980 0.79
70 Development of glucagon sensitivity in neonatal rat liver. J Clin Invest 1976 0.79
71 Responsiveness to glucagon in fetal hearts. Species variability and apparent disparities between changes in beating, adenylate cyclase activation, and cyclic AMP concentration. J Clin Invest 1976 0.79
72 How should we respond to the worldwide diabetes epidemic? Diabetes Care 1998 0.78
73 Effects of fasting and hypophysectomy on FFA uptake and ketone body production by the isolated, perfused rat liver. Diabetes 1970 0.78
74 Evening urine cortisol excretion and DST results in depression and anorexia nervosa. J Psychiatr Res 1989 0.78
75 Studies on the regulation of insulin binding by liver plasma membranes from Zucker fatty rats. Diabetes 1982 0.78
76 Evaluating clinical knowledge across years of medical training. J Med Educ 1981 0.78
77 Augmentation of glucose and amino acid uptake by insulin in the developing rat diaphragm. Am J Physiol 1973 0.78
78 H1 histone sub-type distribution and DNA topoisomerase activity in skeletal muscle of tumour-bearing rats. Cancer Lett 1995 0.77
79 Linkage studies of late-onset familial Alzheimer's disease. Adv Neurol 1990 0.77
80 Protein turnover in skeletal muscle and liver of rats bearing the Walker 256 carcinoma. Experientia 1973 0.77
81 Gustatory and olfactory dysfunction in dementia: not specific to Alzheimer's disease. Neurobiol Aging 1991 0.77
82 Prefrontal lobotomy and hypofrontality in patients with schizophrenia: an integration of the findings. Can J Psychiatry 1992 0.77
83 Brain glucose metabolism in neurologically normal patients with sickle cell disease. Regional alterations. Arch Neurol 1988 0.77
84 The treatment of patients with insulin-requiring diabetes mellitus by primary care physicians. J Community Health 1991 0.77
85 Using hospitalization rates to track the economic costs and benefits of improved diabetes care in the Americas: a proposal for health policy makers. Diabetes Care 2000 0.77
86 Cognitive impairment and depression in mild multiple sclerosis. J Nerv Ment Dis 1992 0.77
87 The stimulation by insulin of amino acid uptake and protein synthesis in the isolated fetal rat heart. Biol Neonate 1971 0.77
88 Leucine oxidation and protein degradation in the extensor digitorum longus and soleus of the tumor-bearing host. Biochem Med 1981 0.77
89 Regression model for predicting dissociations of regional cerebral glucose metabolism in individuals at risk for Huntington's disease. J Cereb Blood Flow Metab 1986 0.76
90 Therapeutic effects of imipramine are counteracted by its metabolite, desipramine, in patients with generalized anxiety disorder. J Clin Psychopharmacol 2000 0.76
91 Use of alternative treatments by patients with psoriasis. Br J Gen Pract 1998 0.76
92 Prolactin response to buspirone challenge in the presence of dopaminergic blockade. Biol Psychiatry 1995 0.76
93 Within-subject transformations of PET regional cerebral blood flow data: ANCOVA, ratio, and Z-score adjustments on empirical data. Hum Brain Mapp 1996 0.76
94 Effect of stimulus intensity on prolactin and cortisol release induced by unilateral electroconvulsive therapy. Neuropsychopharmacology 1996 0.76
95 Models of cognitive deficit and statistical hypotheses: multiple sclerosis, an example. J Clin Exp Neuropsychol 1993 0.76
96 Elevated levels of tau in cerebrospinal fluid: implications for the antemortem diagnosis of Alzheimer's disease elevated levels of tau in cerebrospinal fluid: implications for the antemortem diagnosis of Alzheimer's disease. J Alzheimers Dis 1999 0.76
97 Actin synthesis and polymerization in the liver of fed and fasted rats bearing a Walker 256 carcinoma. Cancer Res 1981 0.76
98 Ultraviolet versus non-ultraviolet light therapy for seasonal affective disorder. J Clin Psychiatry 1991 0.75
99 Giving intravenous drugs. Prepared drugs save time. BMJ 1993 0.75
100 A "touch of sugar" can be fatal. Am Heart J 1998 0.75
101 Cost-effectiveness analyses. Ann Intern Med 2001 0.75
102 Combating sloth as well as gluttony: the role of physical fitness in mortality among men with type 2 diabetes. Ann Intern Med 2000 0.75
103 Glucocorticoid-mediated muscle atrophy: alterations in transcriptional activity of skeletal muscle nuclei. Biochim Biophys Acta 1991 0.75
104 Development of guanylylimidodiphosphate-dependent activation of adenylate cyclase by glucagon in the neonatal rat heart. Pediatr Res 1976 0.75
105 Diabetes mellitus: new approaches to complications. J Indiana State Med Assoc 1982 0.75
106 Implementing clinical paths in a managed care environment. Nurs Econ 1996 0.75
107 Sensory deprivation and aberrant behavior among idiots. Am J Ment Defic 1966 0.75
108 Screening and treatment of diabetic nephropathy by primary care physicians. J Gen Intern Med 1999 0.75
109 Activity of gastrocnemius and soleus polyribosomes in rats bearing the Walker 256 carcinoma. Eur J Cancer 1972 0.75
110 Increased liver alanine in the tumour-bearing host. Altered levels of some enzymes involved in alanine metabolism. Biochem Int 1990 0.75
111 The statistical interaction of cerebral specialization and integration in the interpretation of dynamic brain images. Brain Cogn 1985 0.75
112 Studies on the content and synthesis of soluble actin in livers of normal and tumour-bearing rats [proceedings]. Biochem Soc Trans 1979 0.75
113 Hormonal control of ketosis in the chronically hypophysectomized, pancreatectomized rat. Diabetes 1968 0.75
114 Actin polymerisation in Walker 256 carcinoma cells from solid or ascitic tumours. Cancer Lett 1981 0.75
115 Glucose use correlations: a matter of inference. J Cereb Blood Flow Metab 1986 0.75
116 Cardiac adenylate cyclase: kinetics of synergistic activation by guanosine-5'-triphosphate (GTP) and glucagon. J Mol Cell Cardiol 1980 0.75
117 Alterations in hepatic 5'-nucleotidase in the tumor-bearing rat. Enzyme 1982 0.75
118 Practical management of diabetes for family practitioners. J Indiana State Med Assoc 1978 0.75
119 Actin depolymerising activity in tumour-bearing rats. Cancer Lett 1981 0.75
120 Degradation of hepatic tryptophan pyrrolase in non-pregnant and pregnant rats. Enzyme 1974 0.75
121 A differential effect of the Walker 256 carcinoma on the tyrosine protein kinase activity of liver plasma membrane domains. Cancer Lett 1986 0.75
122 Muscle protein biosynthesis in the tumour-bearing rat. A defect in a post-initiation stage of translation. Biochim Biophys Acta 1975 0.75
123 Evidence that cyclic AMP is not involved in the chronotropic action of glucagon in the adult mouse heart. Endocrinology 1976 0.75
124 Appearances of responses to glucagon in cultured neoatal rat heart cells. Endocrinology 1977 0.75
125 ECT-induced PRL release: a 5-HT1A-mediated event? Biol Psychiatry 1992 0.75
126 Linkage studies in familial Alzheimer's disease. Prog Clin Biol Res 1989 0.75
127 Altered levels of histone H1(0) and DNA topoisomerase activity in the liver of the tumour-bearing rat. Biochem Mol Biol Int 1993 0.75
128 Blockade of the postictal prolactin surge by methysergide. Arch Gen Psychiatry 1989 0.75
129 Hepatic delta 4-steroid hydrogenase in the pregnant rat. Experientia 1971 0.75
130 Effect of the 5-HT2 antagonist ketanserin on the ECT-induced prolactin release. Biol Psychiatry 1989 0.75
131 Sib-pair linkage analysis in late onset Alzheimer's disease. Prog Clin Biol Res 1989 0.75
132 Plasma membrane associated actin in liver of normal and tumour-bearing rats. Biochim Biophys Acta 1985 0.75
133 Glucocorticoid-induced changes in liver: effect of dexamethasone administration on DNA topoisomerase I and II activities and distribution of histone H1 subtypes. Cell Biochem Funct 1994 0.75
134 Hypoglycemia in the diabetic. J Indiana State Med Assoc 1979 0.75
135 The Diabetes Research and Training Centers--a decade of progress in diabetes education. Diabetes Educ 1986 0.75
136 Obituary. James Elwood Ashmore. 1926--1977. Diabetes 1977 0.75
137 Psychometric properties of dichotic words tests. J Clin Neuropsychol 1983 0.75
138 Diabetes mellitus and cerebrovascular disease: prevalence of carotid artery occlusive disease and associated risk factors in 482 adult diabetic patients. Diabetes Care 1983 0.75
139 Cerebrospinal fluid tau protein as a potential diagnostic marker in Alzheimer's disease. Neurobiol Aging 1998 0.75
140 Effect of tumour growth on hepatic neutral ribonuclease and its inhibitor and on RNA polymerase activity of liver nuclei. Enzyme 1983 0.75
141 Actin and actin-binding proteins in plasma membranes derived from Walker 256 ascites or solid tumour cells. Biochim Biophys Acta 1993 0.75
142 Operational and policy considerations of data monitoring in clinical trials: the Diabetes Control and Complications Trial experience. Control Clin Trials 1993 0.75
143 Newer concepts in the therapy of cardiogenic shock. J Indiana State Med Assoc 1966 0.75
144 Glucocorticoid-induced changes in liver: inhibition of nuclear Ca2+, Mg(2+)-dependent endonuclease activity in response to dexamethasone administration. Cell Biochem Funct 1995 0.75
145 Characterization of carbohydrate metabolism in the isolated fetal rat heart. Effects of fasting and alloxan diabetes. Diabetes 1974 0.75
146 Effect of pregnancy and feeding pattern on tryptophan pyrrolase in the rat. Experientia 1972 0.75
147 Response of skeletal muscle RNA polymerases I and II to tumour growth. Biochim Biophys Acta 1988 0.75
148 Effect of morphine on cortisol and prolactin secretion in anorexia nervosa and depression. Clin Endocrinol (Oxf) 1989 0.75
149 Short-term effects of a high-fiber, high-carbohydrate diet in very obese diabetic individuals. Diabetes Care 1987 0.75
150 Securing cooperation from the child dental patient. ASDC J Dent Child 1977 0.75
151 A SUBSTITUTE FOR CROSS WIRES IN THE SPECTROSCOPE. Science 1910 0.75
152 Preventing diabetes complications: living up to the promise. Nutrition 1998 0.75
153 Adenylyl cyclase responsiveness to guanyl nucleotides in the developing rat heart. Pediatr Res 1980 0.75
154 Primary nursing partners. Nurs Manage 1990 0.75
155 What we can learn from Argentina. Diabetes Care 2000 0.75
156 Team case management of chronically mentally ill veterans: a group therapy approach. Nurs Case Manag 2000 0.75
157 Protein metabolism in the tumour-bearing host. Acta Chir Scand Suppl 1980 0.75
158 Forum Two: Unanswered research questions about metabolic control in non-insulin-dependent diabetes mellitus. Ann Intern Med 1996 0.75
159 Empirical support for psychological profiles observed in multiple sclerosis. Arch Neurol 1991 0.75