Published in Psychiatr Genet on January 01, 1996
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A (2001) 9.42
A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. Am J Hum Genet (2003) 2.11
Dopamine D3 receptor Ser9Gly and catechol-o-methyltransferase Val158Met polymorphisms and acute pain in sickle cell disease. Anesth Analg (2014) 1.46
Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controls. Biol Psychiatry (2007) 1.41
Transmission disequilibrium, family controls, and great expectations. Am J Hum Genet (1998) 1.25
The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression. BMC Med Genet (2006) 1.24
Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenics. ACS Chem Biol (2014) 1.09
Mitochondrial localization and function of a subset of 22q11 deletion syndrome candidate genes. Mol Cell Neurosci (2008) 1.06
Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans. Hum Genet (2005) 1.01
An association study of dopamine receptors polymorphisms and the Wisconsin Card Sorting Test in schizophrenia. J Neural Transm (Vienna) (2005) 0.96
Postmortem investigations of the pathophysiology of schizophrenia: the role of susceptibility genes. J Psychiatry Neurosci (2004) 0.88
Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeutics. NeuroRx (2006) 0.84
Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter polymorphism. Psychiatr Genet (2009) 0.83
Nucleocytoplasmic shuttling of dysbindin-1, a schizophrenia-related protein, regulates synapsin I expression. J Biol Chem (2010) 0.82
Biological phenotypes and genetic research on schizophrenia. World Psychiatry (2002) 0.80
A novel SNP in COMT is associated with alcohol dependence but not opiate or nicotine dependence: a case control study. Behav Brain Funct (2011) 0.76
COMT and MAO-A polymorphisms and obsessive-compulsive disorder: a family-based association study. PLoS One (2015) 0.75
Theranostic Biomarkers for Schizophrenia. Int J Mol Sci (2017) 0.75
Neuroanatomical Abnormalities in Violent Individuals with and without a Diagnosis of Schizophrenia. PLoS One (2016) 0.75
Frequency Distribution of COMT Polymorphisms in Greek Patients with Schizophrenia and Controls: A Study of SNPs rs737865, rs4680, and rs165599. ISRN Psychiatry (2012) 0.75
The sequence of the human genome. Science (2001) 101.55
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics (2003) 17.92
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science (1997) 16.09
Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nat Genet (2001) 13.05
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell (1997) 12.83
Combined linkage and association sib-pair analysis for quantitative traits. Am J Hum Genet (1999) 11.22
The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis. Nature (2000) 10.03
A note on the application of the transmission disequilibrium test when a parent is missing. Am J Hum Genet (1995) 7.79
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature (2001) 7.31
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem (1999) 6.88
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science (2001) 6.84
A note on the calculation of empirical P values from Monte Carlo procedures. Am J Hum Genet (2002) 5.06
Schizophrenia following pre-natal exposure to influenza epidemics between 1939 and 1960. Br J Psychiatry (1992) 4.94
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. Proc Natl Acad Sci U S A (1999) 4.90
Meta-analysis of regional brain volumes in schizophrenia. Am J Psychiatry (2000) 4.84
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell (1995) 4.73
Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor. Cell (1991) 4.66
Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors. Cell (2000) 4.51
Activation of memory circuits during cue-elicited cocaine craving. Proc Natl Acad Sci U S A (1996) 4.31
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol Cell Biol (2000) 4.30
Is schizophrenia a neurodevelopmental disorder? Br Med J (Clin Res Ed) (1987) 4.02
Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology (2007) 3.97
The chemistry and biology of unusual DNA structures adopted by oligopurine.oligopyrimidine sequences. FASEB J (1988) 3.84
Schizophrenia and the myth of intellectual decline. Am J Psychiatry (1997) 3.76
Abnormal monitoring of inner speech: a physiological basis for auditory hallucinations. Lancet (1995) 3.74
Model-free analysis and permutation tests for allelic associations. Hum Hered (2000) 3.70
Psychiatric illness in male doctors and controls: an analysis of Scottish hospitals in-patient data. Br J Psychiatry (1977) 3.69
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet (2000) 3.63
Statistical power and optimal design for multisite randomized trials. Psychol Methods (2000) 3.58
Prenatal exposure to the 1957 influenza epidemic and adult schizophrenia: a follow-up study. Br J Psychiatry (1996) 3.57
Olfactory deficits in patients with mild cognitive impairment predict Alzheimer's disease at follow-up. Am J Psychiatry (2000) 3.54
Increased blood flow in Broca's area during auditory hallucinations in schizophrenia. Lancet (1993) 3.42
Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am J Physiol Regul Integr Comp Physiol (2003) 3.37
The Pto kinase conferring resistance to tomato bacterial speck disease interacts with proteins that bind a cis-element of pathogenesis-related genes. EMBO J (1997) 3.19
Comparison of questionnaire and laboratory tests in the detection of excessive drinking and alcoholism. Lancet (1982) 3.11
Pharmacogenetic prediction of clozapine response. Lancet (2000) 3.10
Size and shape effects in the biodistribution of intravascularly injected particles. J Control Release (2009) 3.08
CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling. Oncogene (2011) 3.08
Heritability estimates for psychotic disorders: the Maudsley twin psychosis series. Arch Gen Psychiatry (1999) 3.07
Relapse to cocaine-seeking after hippocampal theta burst stimulation. Science (2001) 2.97
Clinical and molecular cytogenetic characterisation of a newly recognised microdeletion syndrome involving 2p15-16.1. J Med Genet (2006) 2.97
Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging. Arch Gen Psychiatry (2000) 2.93
Lead exposure and intelligence in 7-year-old children: the Yugoslavia Prospective Study. Environ Health Perspect (1997) 2.88
Puberty and the onset of psychosis. Schizophr Res (1993) 2.86
Association between 5-HT2A gene promoter polymorphism and anorexia nervosa. Lancet (1997) 2.83
Using risk calculation to implement an extended relative pair analysis. Ann Hum Genet (1994) 2.79
Functional deficits in patients with mild cognitive impairment: prediction of AD. Neurology (2002) 2.79
Texture information in run-length matrices. IEEE Trans Image Process (1998) 2.77
Analgesic nephropathy: clinical syndrome and prognosis. Br Med J (1971) 2.77
The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2. Proc Natl Acad Sci U S A (2001) 2.75
Schizophrenia after prenatal exposure to 1957 A2 influenza epidemic. Lancet (1991) 2.74
Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses. Hum Gene Ther (1999) 2.73
A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data. Am J Hum Genet (2001) 2.68
Prenatal exposure to influenza epidemics and risk of mental retardation. Eur Arch Psychiatry Clin Neurosci (1995) 2.67
Study of 962 patients indicates progressive muscular atrophy is a form of ALS. Neurology (2009) 2.60
A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders. Mol Psychiatry (1996) 2.60
A voxel-based method for the statistical analysis of gray and white matter density applied to schizophrenia. Neuroimage (1995) 2.58
Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53. Genes Dev (1994) 2.54
Functional anatomy of verbal fluency in people with schizophrenia and those at genetic risk. Focal dysfunction and distributed disconnectivity reappraised. Br J Psychiatry (2000) 2.53
Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains. J Biol Chem (2000) 2.43
Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox. J Cell Biol (2001) 2.40
Association analysis in a variance components framework. Genet Epidemiol (2001) 2.38
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Mol Psychiatry (2008) 2.38
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
Estrogen-related receptor alpha 1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements. Mol Endocrinol (1997) 2.34
Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene. Genes Dev (1998) 2.29
Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactions. EMBO J (1992) 2.29
Phospholipase D: molecular and cell biology of a novel gene family. Biochem J (2000) 2.27
Premorbid social functioning in schizophrenia and bipolar disorder: similarities and differences. Am J Psychiatry (1997) 2.26
An international two-stage genome-wide search for schizophrenia susceptibility genes. Nat Genet (1995) 2.26
The Yugoslavia Prospective Lead Study: contributions of prenatal and postnatal lead exposure to early intelligence. Neurotoxicol Teratol (2001) 2.25
NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation. Oncogene (2011) 2.22
Incidence of schizophrenia in ethnic minorities in London: ecological study into interactions with environment. BMJ (2001) 2.22
Joint linkage of multiple loci for a complex disorder. Am J Hum Genet (1993) 2.20
A program for the monte carlo evaluation of significance of the extended transmission/disequilibrium test. Am J Hum Genet (1999) 2.18
Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. Eur J Neurol (2012) 2.18
Update on Pneumocystis carinii f. sp. hominis typing based on nucleotide sequence variations in internal transcribed spacer regions of rRNA genes. J Clin Microbiol (1998) 2.11
An epidemiological study of insomnia among the Japanese general population. Sleep (2000) 2.09
Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors. Ann N Y Acad Sci (2001) 2.09
Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway. Oncogene (2007) 2.07
Therapygenetics: the 5HTTLPR and response to psychological therapy. Mol Psychiatry (2011) 2.06
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling. Proc Natl Acad Sci U S A (1999) 2.06
Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction. Evaluation of its role in nitric oxide generation in anoxic tissues. J Biol Chem (2001) 2.06
Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration. Invest Ophthalmol Vis Sci (2001) 2.05
Reelin gene alleles and susceptibility to autism spectrum disorders. Mol Psychiatry (2002) 2.05
Genetic contributions to regional variability in human brain structure: methods and preliminary results. Neuroimage (2002) 2.01
Social networks, social support, and mortality among older people in Japan. J Gerontol (1994) 2.01
Predicting global atmospheric ice nuclei distributions and their impacts on climate. Proc Natl Acad Sci U S A (2010) 2.00
Inactivation of erythropoietin leads to defects in cardiac morphogenesis. Development (1999) 2.00
Serum leptin level is a regulator of bone mass. Proc Natl Acad Sci U S A (2004) 1.99
Is schizophrenia disappearing? Lancet (1990) 1.98
School performance in Finnish children and later development of schizophrenia: a population-based longitudinal study. Arch Gen Psychiatry (1999) 1.97
The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides. Diabetes (2004) 1.96
Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control study. BMJ (1999) 1.96
Obstetric complications and age at onset in schizophrenia: an international collaborative meta-analysis of individual patient data. Am J Psychiatry (1997) 1.94