Published in J Crit Care on March 01, 1996
Practice misalignments in randomized controlled trials: Identification, impact, and potential solutions. Anesth Analg (2010) 1.96
The value of positive end-expiratory pressure and Fio₂ criteria in the definition of the acute respiratory distress syndrome. Crit Care Med (2011) 1.64
Choosing a control intervention for a randomised clinical trial. BMC Med Res Methodol (2003) 1.41
Usual care as the control group in clinical trials of nonpharmacologic interventions. Proc Am Thorac Soc (2007) 1.16
Controversial choice of a control intervention in a trial of ventilator therapy in ARDS: standard of care arguments in a randomised controlled trial. J Med Ethics (2005) 0.82
Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet (2001) 17.43
Development of a large-scale de-identified DNA biobank to enable personalized medicine. Clin Pharmacol Ther (2008) 11.67
Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA (2001) 10.63
Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med (1995) 10.29
Long-term cognitive impairment after critical illness. N Engl J Med (2013) 9.20
Risk factors for breast cancer in women with proliferative breast disease. N Engl J Med (1985) 7.22
Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med (2001) 7.14
Treating patients with severe sepsis. N Engl J Med (1999) 6.56
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group. N Engl J Med (1997) 4.98
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Engl J Med (1992) 4.74
Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project. Clin Pharmacol Ther (2012) 4.05
Atypical hyperplastic lesions of the female breast. A long-term follow-up study. Cancer (1985) 3.92
Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance. Am Rev Respir Dis (1986) 2.62
Effects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study Group. Crit Care Med (1999) 2.60
A randomized controlled trial of cold-adapted and inactivated vaccines for the prevention of influenza A disease. J Infect Dis (1994) 2.52
Loss of expression of transforming growth factor beta type II receptor correlates with high tumour grade in human breast in-situ and invasive carcinomas. Histopathology (2000) 2.27
Intraductal carcinoma of the breast: follow-up after biopsy only. Cancer (1982) 2.17
Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis. Ibuprofen in Sepsis Study Group. Crit Care Med (2000) 2.10
Report of the American-European Consensus conference on acute respiratory distress syndrome: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Consensus Committee. J Crit Care (1994) 2.07
Low levels of protein C are associated with poor outcome in severe sepsis. Chest (2001) 2.05
Continued local recurrence of carcinoma 15-25 years after a diagnosis of low grade ductal carcinoma in situ of the breast treated only by biopsy. Cancer (1995) 2.01
A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group. Chest (1997) 2.00
New strategies for clinical trials in patients with sepsis and septic shock. Crit Care Med (2001) 1.95
Invasive breast cancer risk in women with sclerosing adenosis. Cancer (1989) 1.93
Efficacy of inactivated and cold-adapted vaccines against influenza A infection, 1985 to 1990: the pediatric experience. Pediatr Infect Dis J (2001) 1.90
Histologic grading of breast cancer: linkage of patient outcome with level of pathologist agreement. Mod Pathol (2000) 1.88
Breast cancer and CYPIA1, GSTM1, and GSTT1 polymorphisms: evidence of a lack of association in Caucasians and African Americans. Cancer Res (1998) 1.84
Use of pulse oximetry to recognize severity of airflow obstruction in obstructive airway disease: correlation with pulsus paradoxus. Chest (1999) 1.77
Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer. Cancer Res (1998) 1.76
When and to what end do pathologists agree? J Natl Cancer Inst (1998) 1.76
The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am J Respir Crit Care Med (1998) 1.71
Transforming growth factor-beta and breast cancer risk in women with mammary epithelial hyperplasia. J Natl Cancer Inst (1999) 1.67
Lobular neoplasia of the breast: higher risk for subsequent invasive cancer predicted by more extensive disease. Hum Pathol (1991) 1.65
Estrogen receptor gene analysis in estrogen receptor-positive and receptor-negative primary breast cancer. J Natl Cancer Inst (1995) 1.64
Hemocyte-mediated shell mineralization in the eastern oyster. Science (2004) 1.62
Histologic grading of breast carcinoma. A reproducibility study. Cancer (1994) 1.61
Outcomes research in critical care: results of the American Thoracic Society Critical Care Assembly Workshop on Outcomes Research. The Members of the Outcomes Research Workshop. Am J Respir Crit Care Med (1999) 1.53
Control of calcium carbonate nucleation and crystal growth by soluble matrx of oyster shell. Science (1981) 1.52
Prognostic significance of estrogen receptor status in breast cancer in relation to tumor stage, axillary node metastasis, and histopathologic grading. Cancer (1984) 1.49
Analysis of the PvuII restriction fragment-length polymorphism and exon structure of the estrogen receptor gene in breast cancer and peripheral blood. Cancer Res (1992) 1.47
Changing pattern of organ dysfunction in early human sepsis is related to mortality. Crit Care Med (2000) 1.36
Anatomic markers of human premalignancy and risk of breast cancer. Cancer (1990) 1.35
The American-European Consensus Conference on ARDS, part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling. Intensive Care Med (1998) 1.32
Estimating the undetected burden of influenza hospitalizations in children. Epidemiol Infect (2006) 1.29
Retrieval of renal function by revascularization. Study of preoperative outcome predictors. Ann Surg (1985) 1.29
Suppression of resistant ventricular arrhythmias by twice daily dosing with flecainide. Am J Cardiol (1981) 1.28
Breast cancer risk associated with proliferative disease, age at first birth, and a family history of breast cancer. Am J Epidemiol (1987) 1.25
Subsequent breast carcinoma risk after biopsy with atypia in a breast papilloma. Cancer (1996) 1.23
New ways to reduce unnecessary variation and improve outcomes in the intensive care unit. Curr Opin Crit Care (2001) 1.23
Effect of N-acetylcysteine on the pulmonary response to endotoxin in the awake sheep and upon in vitro granulocyte function. J Clin Invest (1984) 1.21
p53 gene mutations and steroid receptor status in breast cancer. Clinicopathologic correlations and prognostic assessment. Cancer (1994) 1.18
No elevation in long-term breast carcinoma risk for women with fibroadenomas that contain atypical hyperplasia. Cancer (2001) 1.17
Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis. Pharmacogenomics J (2012) 1.15
In vitro versus in vivo comparison of endotracheal tube airflow resistance. Am Rev Respir Dis (1989) 1.07
Endotoxin-induced ileal Vo2-Do2 alterations do not correlate with the severity of ileal injury. J Crit Care (1997) 1.05
A simple multiple system organ failure scoring system predicts mortality of patients who have sepsis syndrome. Chest (1993) 1.05
Suppression of chronic ventricular arrhythmias with propranolol. Circulation (1979) 1.04
Immunologic therapy for ARDS, septic shock, and multiple-organ failure. Chest (1993) 1.04
Mediastinal fibrosis is associated with human leukocyte antigen-A2. Chest (2000) 1.03
Acid aspiration-induced acute lung injury causes leukocyte-dependent systemic organ injury. J Appl Physiol (1985) (1993) 1.01
Effect of bronchodilators on lung mechanics in the acute respiratory distress syndrome (ARDS). Chest (1994) 1.00
Sensitivity of Fisher's exact test to minor perturbations in 2 x 2 contingency tables. Stat Med (1987) 0.99
Campylobacter fetus ssp fetus cholecystitis and relapsing bacteremia in a patient with acquired immunodeficiency syndrome. South Med J (1984) 0.98
Direct vasodilator effect of hyperventilation-induced hypocarbia in autonomic failure patients. Am J Med Sci (1991) 0.98
Prostacyclin and thromboxane A2 formation is increased in human sepsis syndrome. Effects of cyclooxygenase inhibition. Am Rev Respir Dis (1991) 0.98
Microwave irradiation as a generator of heat for histological fixation. Stain Technol (1974) 0.96
Significance of glutathione in lung disease and implications for therapy. Am J Med Sci (1994) 0.95
p53 mutations are confined to the comedo type ductal carcinoma in situ of the breast. Immunohistochemical and sequencing data. Lab Invest (1994) 0.95
Anatomic indicators (histologic and cytologic) of increased breast cancer risk. Breast Cancer Res Treat (1993) 0.93
Probabilistic approach to the reporting of fine-needle aspiration cytology of the breast. Cancer (1997) 0.92
Airway and lung in sepsis. Intensive Care Med (2001) 0.92
Total suppression of ventricular arrhythmias by encainide. Pharmacokinetic and electrocardiographic characteristics. N Engl J Med (1980) 0.91
Comparison of elastin peptide concentrations in body fluids from healthy volunteers, smokers, and patients with chronic obstructive pulmonary disease. Am Rev Respir Dis (1992) 0.91
Ductal involvement by cells of atypical lobular hyperplasia in the breast: a long-term follow-up study of cancer risk. Hum Pathol (1988) 0.90
Androgen receptor CAG repeat lengths in ductal carcinoma in situ of breast, longest in apocrine variety. Breast (2000) 0.90
Airway complications from free-basing cocaine. Chest (1989) 0.90
Antiarrhythmic efficacy, pharmacokinetics and safety of N-acetylprocainamide in human subjects: comparison with procainamide. Am J Cardiol (1980) 0.90
The effect of PEEP on cardiac output. Chest (1983) 0.90
Quantification of organ dysfunction: seeking standardization. Crit Care Med (1998) 0.89
Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression. Oncogene (2011) 0.89
Septicemia and lung injury. Clin Lab Med (1983) 0.89
Persistent generation of peptido leukotrienes in patients with the adult respiratory distress syndrome. Am Rev Respir Dis (1991) 0.89
Acute respiratory distress syndrome. Potential pharmacologic interventions. Clin Chest Med (2000) 0.88
Evaluation of a new highly purified pertussis vaccine in infants and children. J Infect Dis (1989) 0.88
Immunohistochemical analysis of receptor tyrosine kinase signal transduction activity in chordoma. Neuropathol Appl Neurobiol (2007) 0.88
The role of cyclooxygenase products in lung injury induced by tumor necrosis factor in sheep. Am Rev Respir Dis (1992) 0.88
Aortic and renal vascular disease. Factors affecting the value of combined procedures. Ann Surg (1984) 0.88
A survey of 251 patients with acute syphilis treated in the collaborative penicillin study of 1943-1950. Sex Transm Dis (1982) 0.87
Ileal VO(2)-O(2) alterations induced by endotoxin correlate with severity of mitochondrial injury. Am J Respir Crit Care Med (1999) 0.87
Papillary apocrine change of the breast: associations with atypical hyperplasia and risk of breast cancer. Cancer Epidemiol Biomarkers Prev (1996) 0.87
A retrospective cohort study of Histologic risk factors in breast cancer patients. Cancer (1982) 0.87
Effect of cyclooxygenase inhibition on amphotericin B-induced lung injury in awake sheep. J Infect Dis (1992) 0.86