Published in J Infect Dis on January 01, 1997
Iron deficiency protects against severe Plasmodium falciparum malaria and death in young children. Clin Infect Dis (2012) 3.69
Polarization dictates iron handling by inflammatory and alternatively activated macrophages. Haematologica (2010) 1.36
Iron at the interface of immunity and infection. Front Pharmacol (2014) 1.31
Implications of malaria on iron deficiency control strategies. Adv Nutr (2012) 1.07
Parasite maturation and host serum iron influence the labile iron pool of erythrocyte stage Plasmodium falciparum. Br J Haematol (2013) 0.96
High levels of inducible nitric oxide synthase mRNA are associated with increased monocyte counts in blood and have a beneficial role in Plasmodium falciparum malaria. Infect Immun (2000) 0.94
Effect of nutrient deficiencies on in vitro Th1 and Th2 cytokine response of peripheral blood mononuclear cells to Plasmodium falciparum infection. Malar J (2010) 0.79
Serum levels of cytokines in chronic liver diseases. Gastroenterology (1992) 3.47
Neopterin as a marker for activated cell-mediated immunity: application in HIV infection. Immunol Today (1988) 3.13
Simultaneous measurement of serum tryptophan and kynurenine by HPLC. Clin Chem (1997) 2.39
Incorporation of six additional proteins to complete the assembly map of the 50 S subunit from Escherichia coli ribosomes. J Biol Chem (1987) 2.15
Primary iron overload in African Americans. Am J Med (1996) 2.08
Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase. FEBS Lett (1991) 1.96
L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin. J Biol Chem (2001) 1.95
Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts. J Exp Med (1990) 1.81
Correct folding of circularly permuted variants of a beta alpha barrel enzyme in vivo. Science (1989) 1.76
Congenital malaria in a hyperendemic area. Am J Trop Med Hyg (1991) 1.76
Heterologous expression of Arabidopsis phytochrome B in transgenic potato influences photosynthetic performance and tuber development. Plant Physiol (1999) 1.72
Congenital polycythemia in Chuvashia. Blood (1997) 1.72
Neopterin as a predictive marker for disease progression in human immunodeficiency virus type 1 infection. Clin Chem (1989) 1.66
Interleukin-1 receptor antagonist in differential diagnosis of inflammatory bowel diseases. Eur J Gastroenterol Hepatol (1995) 1.64
Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats. J Clin Invest (1998) 1.62
The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain. J Biol Chem (1994) 1.61
Ascitic interleukin-12 is an independent prognostic factor in ovarian cancer. J Clin Oncol (1998) 1.61
Neopterin as marker for activation of cellular immunity: immunologic basis and clinical application. Adv Clin Chem (1989) 1.59
Impaired nocturnal secretion of melatonin in coronary heart disease. Lancet (1995) 1.59
Iron regulates nitric oxide synthase activity by controlling nuclear transcription. J Exp Med (1994) 1.55
Iron chelation with desferrioxamine B in adults with asymptomatic Plasmodium falciparum parasitemia. Blood (1992) 1.53
Haptoglobin polymorphism and mortality in patients with tuberculosis. Int J Tuberc Lung Dis (2000) 1.53
Association of pulmonary tuberculosis with increased dietary iron. J Infect Dis (2001) 1.51
Systematic study of four years of internship. Pediatrics (1980) 1.51
Non-transferrin-bound iron and hepatic dysfunction in African dietary iron overload. J Gastroenterol Hepatol (1999) 1.50
Characterization of heme-deficient neuronal nitric-oxide synthase reveals a role for heme in subunit dimerization and binding of the amino acid substrate and tetrahydrobiopterin. J Biol Chem (1996) 1.45
Human macrophages degrade tryptophan upon induction by interferon-gamma. Life Sci (1987) 1.42
Tetrahydrobiopterin biosynthesis, utilization and pharmacological effects. Curr Drug Metab (2002) 1.40
Reactive oxygen species mediate endothelium-dependent relaxations in tetrahydrobiopterin-deficient mice. Arterioscler Thromb Vasc Biol (2001) 1.40
Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms. J Acquir Immune Defic Syndr (1990) 1.39
Protracted infection of pacemaker leads with development of large vegetations: three years follow up. Case report. Vnitr Lek (2003) 1.39
Atrial natriuretic peptide (ANP), aldosterone, angiotensin II and renin in the 'low T3 syndrome' in organ donors. Infusionsther Transfusionsmed (1992) 1.39
Kinetics and mechanism of tetrahydrobiopterin-induced oxidation of nitric oxide. J Biol Chem (1995) 1.37
Metabolic fate of peroxynitrite in aqueous solution. Reaction with nitric oxide and pH-dependent decomposition to nitrite and oxygen in a 2:1 stoichiometry. J Biol Chem (1997) 1.35
Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP. J Biol Chem (1993) 1.35
Distribution of transferrin saturation in an Australian population: relevance to the early diagnosis of hemochromatosis. Gastroenterology (1998) 1.35
Characterization of the inducible nitric oxide synthase oxygenase domain identifies a 49 amino acid segment required for subunit dimerization and tetrahydrobiopterin interaction. Biochemistry (1997) 1.30
Iron and Mycobacterium tuberculosis infection. J Clin Virol (2001) 1.28
Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole. Neuropharmacology (1994) 1.28
Production of IL-12 by human monocyte-derived dendritic cells is optimal when the stimulus is given at the onset of maturation, and is further enhanced by IL-4. J Immunol (2001) 1.24
In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn Schmiedebergs Arch Pharmacol (1995) 1.23
Iron overload: causes and consequences. Annu Rev Nutr (1987) 1.23
Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells. Biochem J (1992) 1.23
The phosphatidyl-myo-inositol anchor of the lipoarabinomannans from Mycobacterium bovis bacillus Calmette Guérin. Heterogeneity, structure, and role in the regulation of cytokine secretion. J Biol Chem (1997) 1.21
Cellular and humoral immune responses in patients with metastatic renal cell carcinoma after vaccination with antigen pulsed dendritic cells. J Urol (1999) 1.20
Bacillus Calmette-Guérin mycobacteria stimulate human blood dendritic cells. Int J Cancer (1997) 1.19
Characteristics of interferon induced tryptophan metabolism in human cells in vitro. Biochim Biophys Acta (1989) 1.19
Endogenous IFN-gamma during human bone marrow transplantation. Analysis of serum levels of interferon and interferon-dependent secondary messages. Transplantation (1990) 1.18
Iron modulates interferon-gamma effects in the human myelomonocytic cell line THP-1. Exp Hematol (1992) 1.17
Tetrahydrobiopterin-free neuronal nitric oxide synthase: evidence for two identical highly anticooperative pteridine binding sites. Biochemistry (1996) 1.16
Immune activation and decreased tryptophan in patients with HIV-1 infection. J Interferon Res (1990) 1.15
Tuberculosis and iron overload in Africa: a review. Cent Afr J Med (1997) 1.15
The course of anaemia after the treatment of acute, falciparum malaria. Ann Trop Med Parasitol (1998) 1.14
Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection. Immunol Lett (1991) 1.14
Interferon-gamma concentrations are increased in sera from individuals infected with human immunodeficiency virus type 1. J Acquir Immune Defic Syndr (1989) 1.14
Neopterin modulates toxicity mediated by reactive oxygen and chloride species. FEBS Lett (1993) 1.14
Evidence-based recommendations for the management of ankylosing spondylitis: systematic literature search of the 3E Initiative in Rheumatology involving a broad panel of experts and practising rheumatologists. Rheumatology (Oxford) (2008) 1.13
Determination of neopterin in serum and urine. Clin Chem (1987) 1.12
Bone marrow macrophage iron grade and survival of HIV-seropositive patients. AIDS (1999) 1.12
Tumour necrosis factor-alpha plasma level in patients with type 1 diabetes mellitus and its association with glycaemic control and cardiovascular risk factors. J Intern Med (2000) 1.11
Prevalence of heterozygotes for hemochromatosis in the white population of the United States. Blood (1995) 1.10
Influence of hemoglobin E trait on the severity of Falciparum malaria. J Infect Dis (1999) 1.09
Electrochemistry of pterin cofactors and inhibitors of nitric oxide synthase. Nitric Oxide (2001) 1.09
Severe anaemia in Zambian children with Plasmodium falciparum malaria. Trop Med Int Health (2000) 1.08
Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1. AIDS (1989) 1.08
Tumour necrosis factor-alpha and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells. Biol Chem Hoppe Seyler (1989) 1.08
Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation. Kidney Int (2006) 1.08
Who will get AIDS? Lancet (1986) 1.07
Nitric oxide synthase is induced in sporulation of Physarum polycephalum. Genes Dev (2001) 1.07
Effect of iron chelation therapy on mortality in Zambian children with cerebral malaria. Trans R Soc Trop Med Hyg (1998) 1.07
Pulmonary sarcoidosis: patterns of cytokine release in vitro. Eur Respir J (1996) 1.07
IFN-mediated induction of MHC antigen expression on human keratinocytes and its influence on in vitro alloimmune responses. J Immunol (1988) 1.06
Formation of a protonated trihydrobiopterin radical cation in the first reaction cycle of neuronal and endothelial nitric oxide synthase detected by electron paramagnetic resonance spectroscopy. J Biol Inorg Chem (2001) 1.06
Prolonged macrophage activation and persistent anaemia in children with complicated malaria. Trop Med Int Health (1998) 1.05
IL-6 secretion by human peritoneal mesothelial and ovarian cancer cells. Cytokine (1995) 1.05
Immune activation and the anaemia associated with chronic inflammatory disorders. Eur J Haematol (1991) 1.05
Neopterin in clinical practice. Clin Chim Acta (1991) 1.04
Dietary iron overload persists in rural sub-Saharan Africa. Lancet (1986) 1.04
Chronomics, neuroendocrine feedsidewards and the recording and consulting of nowcasts--forecasts of geomagnetics. Biomed Pharmacother (2005) 1.03
Posttransplant neopterin excretion in renal allograft recipients--a reliable diagnostic aid for acute rejection and a predictive marker of long-term graft survival. Transplantation (1991) 1.03
In vivo activation of CD4+ cells in AIDS. Science (1987) 1.02
Serum levels of interleukin-6 in multiple myeloma and other hematological disorders: correlation with disease activity and other prognostic parameters. Ann Hematol (1991) 1.02
Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1) upon cytokine treatment. Cancer Res (1990) 1.01
Phase I trial of intravenous aviscumine (rViscumin) in patients with solid tumors: a study of the European Organization for Research and Treatment of Cancer New Drug Development Group. Ann Oncol (2004) 1.01
Influence of hemoglobin E trait on the antimalarial effect of artemisinin derivatives. J Infect Dis (2000) 1.01
Carbonyl iron therapy for iron deficiency anemia. Blood (1986) 1.00
Potential of urinary neopterin excretion in differentiating chronic non-A, non-B hepatitis from fatty liver. Lancet (1987) 1.00
Protein kinase C phosphorylates and activates GTP cyclohydrolase I in rat renal mesangial cells. Biochem Biophys Res Commun (1998) 1.00
In-vitro and in-vivo studies on the induction of neopterin biosynthesis by cytokines, alloantigens and lipopolysaccharide (LPS). Clin Exp Immunol (1988) 0.99
[Serum neopterin determination for the additional safeguarding of blood transfusions. Our experiences with 76,587 blood donors]. Dtsch Med Wochenschr (1989) 0.99
Urinary neopterin reflects clinical activity in patients with rheumatoid arthritis. Arthritis Rheum (1986) 0.99
Cross reactivity of three T cell attracting murine chemokines stimulating the CXC chemokine receptor CXCR3 and their induction in cultured cells and during allograft rejection. Eur J Immunol (2001) 0.99
Ca2+/calmodulin-dependent nitric oxide synthase activity in the human cervix carcinoma cell line ME-180. Biochem J (1993) 0.98
Evaluation of cytokines and cytokine-induced secondary messages in sera of patients after liver transplantation. Transplantation (1990) 0.98
Efficacy and safety of a combined rituximab chemotherapy during pregnancy. J Clin Oncol (2001) 0.98