The structural basis of negative cooperativity: receptors and enzymes.

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Structural basis for negative cooperativity in growth factor binding to an EGF receptor. Cell (2010) 1.79

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Symmetric allosteric mechanism of hexameric Escherichia coli arginine repressor exploits competition between L-arginine ligands and resident arginine residues. PLoS Comput Biol (2010) 0.87

Putting together structures of epidermal growth factor receptors. Curr Opin Struct Biol (2014) 0.86

The structure and allosteric regulation of glutamate dehydrogenase. Neurochem Int (2010) 0.85

Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers. Nat Commun (2012) 0.84

Receptor oligomerization in family B1 of G-protein-coupled receptors: focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity. Front Endocrinol (Lausanne) (2012) 0.84

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Multiple roles of mobile active center loops in the E1 component of the Escherichia coli pyruvate dehydrogenase complex - Linkage of protein dynamics to catalysis. J Mol Catal B Enzym (2009) 0.81

Kinetic and X-ray structural evidence for negative cooperativity in substrate binding to nicotinate mononucleotide adenylyltransferase (NMAT) from Bacillus anthracis. J Mol Biol (2008) 0.80

Modeling the role of negative cooperativity in metabolic regulation and homeostasis. PLoS One (2012) 0.78

One substrate, five products: reactions catalyzed by the dihydroneopterin aldolase from Mycobacterium tuberculosis. J Am Chem Soc (2012) 0.77

Structural and Functional Characterization of the PaaI Thioesterase from Streptococcus pneumoniae Reveals a Dual Specificity for Phenylacetyl-CoA and Medium-chain Fatty Acyl-CoAs and a Novel CoA-induced Fit Mechanism. J Biol Chem (2015) 0.75

Complete integrability of information processing by biochemical reactions. Sci Rep (2016) 0.75

Homodimerization enhances both sensitivity and dynamic range of the ligand-binding domain of type 1 metabotropic glutamate receptor. FEBS Lett (2016) 0.75

Crystal structure of glutamate-1-semialdehyde-2,1-aminomutase from Arabidopsis thaliana. Acta Crystallogr F Struct Biol Commun (2016) 0.75

Evolution of Negative Cooperativity in Glutathione Transferase Enabled Preservation of Enzyme Function. J Biol Chem (2016) 0.75