L R Languino

Author PubWeight™ 57.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1. Nature 1990 4.64
2 Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix. J Clin Invest 1990 2.56
3 Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt. Circ Res 2000 2.39
4 Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs. J Biol Chem 1987 2.29
5 Transforming growth factor-beta regulates production of proteoglycans by mesangial cells. Kidney Int 1990 2.04
6 Alpha 2 beta 1 integrins from different cell types show different binding specificities. J Biol Chem 1990 1.92
7 Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Oncogene 2009 1.87
8 Interaction between fibrinogen and cultured endothelial cells. Induction of migration and specific binding. J Clin Invest 1985 1.79
9 The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration. J Cell Sci 1998 1.70
10 Prostatic carcinoma cell migration via alpha(v)beta3 integrin is modulated by a focal adhesion kinase pathway. Cancer Res 1999 1.66
11 An alternative cytoplasmic domain of the integrin beta 3 subunit. Proc Natl Acad Sci U S A 1989 1.61
12 Regulation of survivin expression by IGF-1/mTOR signaling. Oncogene 2006 1.59
13 Fibrinogen induces adhesion, spreading, and microfilament organization of human endothelial cells in vitro. J Cell Biol 1987 1.59
14 Integrins and prostate cancer metastases. Cancer Metastasis Rev 2001 1.51
15 Substrate specificity of alpha(v)beta(3) integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT pathway activation. J Biol Chem 2000 1.43
16 Inhibition of cell cycle progression by the alternatively spliced integrin beta 1C. Science 1995 1.38
17 Molecular identification of a novel fibrinogen binding site on the first domain of ICAM-1 regulating leukocyte-endothelium bridging. J Biol Chem 1997 1.23
18 p27(kip1) acts as a downstream effector of and is coexpressed with the beta1C integrin in prostatic adenocarcinoma. J Clin Invest 1999 1.19
19 Interaction of fibronectin with cultured human endothelial cells: characterization of the specific receptor. Blood 1989 1.18
20 Structural recognition of a novel fibrinogen gamma chain sequence (117-133) by intercellular adhesion molecule-1 mediates leukocyte-endothelium interaction. J Biol Chem 1995 1.07
21 High-affinity self-reactive human antibodies by design and selection: targeting the integrin ligand binding site. Proc Natl Acad Sci U S A 1993 1.06
22 Down-regulation of beta 1C integrin, an inhibitor of cell proliferation, in prostate carcinoma. Am J Pathol 1996 1.06
23 The novel structural motif Gln795-Gln802 in the integrin beta 1C cytoplasmic domain regulates cell proliferation. J Biol Chem 1995 1.05
24 Beta1C integrin in epithelial cells correlates with a nonproliferative phenotype: forced expression of beta1C inhibits prostate epithelial cell proliferation. Am J Pathol 1998 1.03
25 The localization of a platelet GpIIb-IIIa-related protein in endothelial cell adhesion structures. Blood 1988 1.03
26 The alpha v beta 3 integrin associates with a 190-kDa protein that is phosphorylated on tyrosine in response to platelet-derived growth factor. J Biol Chem 1993 1.01
27 Regulation of mRNA and protein levels of beta1 integrin variants in human prostate carcinoma. Am J Pathol 2000 1.00
28 Alternatively spliced variants: a new view of the integrin cytoplasmic domain. Matrix Biol 1997 0.97
29 Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease. Br J Cancer 2011 0.97
30 Fibrinogen mediates leukocyte-endothelium bridging in vivo at low shear forces. Blood 1996 0.93
31 Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways. Mol Biol Cell 2000 0.92
32 Thrombospondin-platelet interactions. Role of divalent cations, wall shear rate, and platelet membrane glycoproteins. J Clin Invest 1993 0.91
33 Integrin laminin receptor profile of pulmonary squamous cell and adenocarcinomas. Hum Pathol 1998 0.90
34 Platelets express a membrane protein complex immunologically related to the fibroblast fibronectin receptor and distinct from GPIIb/IIIa. Blood 1987 0.87
35 Role of TGF-beta 1 in experimental glomerulonephritis. Ciba Found Symp 1991 0.84
36 Down-regulation of beta(1C) integrin in breast carcinomas correlates with high proliferative fraction, high histological grade, and larger size. Am J Pathol 2000 0.84
37 Uptake of aspartate aminotransferase into mitochondria in vitro depends on the transmembrane pH gradient. Biochem J 1982 0.83
38 Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog. Am J Physiol 1985 0.81
39 Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery. Thromb Res 1985 0.79
40 Modulation of cell proliferation by the integrin cytoplasmic domain. Kidney Int 1997 0.78
41 Epitope-specific antibodies to the beta(1C) integrin cytoplasmic domain variant. Exp Mol Pathol 2001 0.77
42 Platelet adhesion to subendothelium--effect of shear rate, hematocrit and platelet count on the dynamic equilibrium between platelets adhering to and detaching from the surface. Thromb Haemost 1985 0.77
43 Regulation of MCP-3 and BRCA2 mRNA expression levels by beta(1) integrins. Exp Mol Pathol 2001 0.76
44 Prostacyclin and thromboxane levels during cardiac ischemia in dogs. Adv Prostaglandin Thromboxane Leukot Res 1985 0.75
45 Application of polymerase chain reaction for the discovery of new adhesion molecule family members. Methods Mol Biol 1999 0.75
46 Human platelet adhesion to subendothelium under controlled hemodynamic conditions: a methodological approach. Methods Find Exp Clin Pharmacol 1985 0.75
47 Expression of heterologous integrin genes. Methods Mol Biol 1999 0.75