Published in J Clin Invest on January 15, 1997
EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3. Mol Cell Biol (2004) 3.33
A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma. Nat Med (2009) 2.17
The TET family of proteins: functions and roles in disease. J Mol Cell Biol (2009) 1.97
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma. PLoS Med (2007) 1.82
GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein. J Biol Chem (2009) 1.56
Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening. J Natl Cancer Inst (2011) 1.55
High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition. PLoS One (2010) 1.54
Tumoral TP53 and/or CDKN2A alterations are not reliable prognostic biomarkers in patients with localized Ewing sarcoma: a report from the Children's Oncology Group. Pediatr Blood Cancer (2014) 1.43
Promiscuous partnerships in Ewing's sarcoma. Cancer Genet (2011) 1.41
Oncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma. Clin Cancer Res (2010) 1.36
Ewing's sarcoma: diagnostic, prognostic, and therapeutic implications of molecular abnormalities. J Clin Pathol (2003) 1.35
Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription. Genome Res (2011) 1.29
Association of EWS-FLI1 type 1 fusion with lower proliferative rate in Ewing's sarcoma. Am J Pathol (2000) 1.22
The biology of ewing sarcoma. ISRN Oncol (2013) 1.19
EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance. Mol Cancer Res (2012) 1.04
Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma. Mol Cancer Ther (2008) 1.02
Pathology of Ewing's sarcoma/PNET: Current opinion and emerging concepts. Indian J Orthop (2010) 1.02
Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA. Br J Pharmacol (2009) 1.01
Animal models of soft-tissue sarcoma. Dis Model Mech (2010) 1.01
Downregulation and forced expression of EWS-Fli1 fusion gene results in changes in the expression of G(1)regulatory genes. Br J Cancer (2001) 0.99
Mesenchymal Stem Cells and the Origin of Ewing's Sarcoma. Sarcoma (2010) 0.99
Molecular pathogenesis and targeted therapeutics in Ewing sarcoma/primitive neuroectodermal tumours. Clin Sarcoma Res (2012) 0.94
Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells. Ann Rheum Dis (2002) 0.89
Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis. Nucleic Acids Res (2013) 0.89
Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity. Front Oncol (2012) 0.82
Bone sarcomas: from biology to targeted therapies. Sarcoma (2012) 0.82
Targeting the p53 Pathway in Ewing Sarcoma. Sarcoma (2010) 0.82
gamma-Glutamyl transpeptidase expression in Ewing's sarcoma cells: up-regulation by interferons. Biochem J (2002) 0.82
Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model. Oncotarget (2016) 0.81
Preferential down-regulation of phospholipase C-beta in Ewing's sarcoma cells transfected with antisense EWS-Fli-1. Br J Cancer (2000) 0.81
Progress in the molecular biology of ewing tumors. Sarcoma (1998) 0.80
Transformation induced by Ewing's sarcoma associated EWS/FLI-1 is suppressed by KRAB/FLI-1. Br J Cancer (2003) 0.79
Xenograft and genetically engineered mouse model systems of osteosarcoma and Ewing's sarcoma: tumor models for cancer drug discovery. Expert Opin Drug Discov (2013) 0.78
Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1. Oncotarget (2016) 0.78
Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma. Sarcoma (2011) 0.78
YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model. Oncotarget (2015) 0.78
Anti-Epileptic Drug Targets Ewing Sarcoma. J Pharm Sci Pharmacol (2014) 0.78
Current concepts in the molecular genetics of pediatric brain tumors: implications for emerging therapies. Childs Nerv Syst (2006) 0.78
Potential approaches to the treatment of Ewing's sarcoma. Oncotarget (2016) 0.77
Molecular approaches to sarcoma therapy. Sarcoma (2002) 0.77
Ewing's Sarcoma: Development of RNA Interference-Based Therapy for Advanced Disease. ISRN Oncol (2012) 0.77
Molecular alterations in pediatric sarcomas: potential targets for immunotherapy. Sarcoma (1998) 0.76
Recent advances in targeted therapy for Ewing sarcoma. F1000Res (2016) 0.75
Localizing potentially active post-transcriptional regulations in the Ewing's sarcoma gene regulatory network. BMC Syst Biol (2010) 0.75
Potential molecular targets for Ewing's sarcoma therapy. Indian J Med Paediatr Oncol (2012) 0.75
Preclinical Justification of pbi-shRNA EWS/FLI1 Lipoplex (LPX) Treatment for Ewing's Sarcoma. Mol Ther (2016) 0.75
Detection of EWS/FLI-1 fusion in non-Ewing soft tissue tumors. J Med Life (2014) 0.75
Proteasomal degradation of the EWS-FLI1 fusion protein is regulated by a single lysine residue. J Biol Chem (2016) 0.75
Detection of EWS/FLI-1 fusion in non-Ewing soft tissue tumors. J Med Life (2015) 0.75
EWS-FLI1 positively regulates autophagy by increasing ATG4B expression in Ewing sarcoma cells. Int J Mol Med (2017) 0.75
Quantitation of mRNA by the polymerase chain reaction. Proc Natl Acad Sci U S A (1989) 15.69
Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction. Proc Natl Acad Sci U S A (1990) 10.01
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature (1992) 7.68
Chromosomal translocations in human cancer. Nature (1994) 6.44
Competitive PCR. Nature (1992) 5.96
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Nature (1993) 5.69
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. J Biol Chem (1989) 5.64
Antisense oligonucleotides as therapeutic agents--is the bullet really magical? Science (1993) 5.50
Primary response genes induced by growth factors and tumor promoters. Annu Rev Biochem (1991) 5.48
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet (1993) 5.00
The Ewing family of tumors--a subgroup of small-round-cell tumors defined by specific chimeric transcripts. N Engl J Med (1994) 4.65
Myc and Max proteins possess distinct transcriptional activities. Nature (1992) 4.16
Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma. Nat Genet (1993) 4.12
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG. Nat Genet (1994) 3.17
Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet (1993) 3.11
Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. Nat Genet (1994) 3.10
Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proc Natl Acad Sci U S A (1993) 3.07
Role of RNase H in hybrid-arrested translation by antisense oligonucleotides. Proc Natl Acad Sci U S A (1988) 2.98
The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Mol Cell Biol (1993) 2.84
Nuclear proto-oncogenes fos and jun. Annu Rev Cell Biol (1990) 2.82
EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts. Nat Genet (1993) 2.72
Fusion of the EWS and WT1 genes in the desmoplastic small round cell tumor. Cancer Res (1994) 2.33
A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. Oncogene (1995) 2.26
Chromosome translocation in peripheral neuroepithelioma. N Engl J Med (1984) 2.22
Translation arrest by oligodeoxynucleotides complementary to mRNA coding sequences yields polypeptides of predetermined length. Nucleic Acids Res (1986) 2.21
DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma. Mol Cell Biol (1994) 2.18
Cytogenetic characterization of selected small round cell tumors of childhood. Cancer Genet Cytogenet (1986) 2.04
Dynamic model of differentiation in Ewing's sarcoma cells. Comparative analysis of morphologic, immunocytochemical, and oncogene expression parameters. Lab Invest (1992) 1.75
Experimental evidence for a neural origin of Ewing's sarcoma of bone. Am J Pathol (1987) 1.68
Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression. Mol Cell Biol (1992) 1.61
Chromosomal aberrations in soft tissue tumors. Relevance to diagnosis, classification, and molecular mechanisms. Am J Pathol (1994) 1.60
Antisense RNA inhibits splicing of pre-mRNA in vitro. EMBO J (1988) 1.58
The FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities. J Biol Chem (1994) 1.56
EWS/Fli-1 chimeric protein is a transcriptional activator. Cancer Res (1993) 1.52
Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis. Mol Cell Biol (1995) 1.47
EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro. Cell Growth Differ (1996) 1.40
Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1. Oncogene (1994) 1.40
Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts. Oncogene (1995) 1.40
Proliferative activation of quiescent Rat-1A cells by delta FosB. Mol Cell Biol (1993) 1.27
The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing's sarcoma, encodes a transcriptional activator with DNA-binding specificities distinct from other Ets family members. Oncogene (1993) 1.27
Progress toward oligonucleotide therapeutics: pharmacodynamic properties. FASEB J (1993) 1.25
EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations. J Clin Invest (1994) 1.20
Prevalence of multidrug resistance related to activation of the mdr1 gene in human sarcoma mutants derived by single-step doxorubicin selection. Cancer Res (1994) 1.16
Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system. J Clin Invest (1987) 1.15
Indistinguishable patterns of protooncogene expression in two distinct but closely related tumors: Ewing's sarcoma and neuroepithelioma. Cancer Res (1988) 1.13
Myeloablative radiochemotherapy and hematopoietic stem-cell rescue in poor-prognosis Ewing's sarcoma. J Clin Oncol (1993) 1.07
Impact of megatherapy in children with high-risk Ewing's tumours in complete remission: a report from the EBMT Solid Tumour Registry. Bone Marrow Transplant (1995) 1.04
Ewing sarcoma of the pelvis. Clinicopathological features and treatment. J Bone Joint Surg Am (1993) 1.04
The contribution of increased collagen synthesis to human glomerulosclerosis: a quantitative analysis of alpha 2IV collagen mRNA expression by competitive polymerase chain reaction. J Exp Med (1992) 0.95
Ewing sarcoma of bone in infants and toddlers. A clinicopathologic report from the Intergroup Ewing's Study. Cancer (1993) 0.95
Cyclic AMP-regulated synthesis of the tissue inhibitors of metalloproteinases suppresses the invasive potential of the human fibrosarcoma cell line HT1080. Cancer Res (1995) 0.92
The establishment and characterization of a peripheral neuroepithelioma cell line in soft tissue of extremity. Lab Invest (1995) 0.81
Cell motility by labile association of molecules. The nature of mitotic spindle fibers and their role in chromosome movement. J Gen Physiol (1967) 13.71
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science (1997) 13.67
Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors. Science (1997) 8.95
[Myocardial stunning due to simultaneous multivessel coronary spasms: a review of 5 cases]. J Cardiol (1991) 7.95
A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res (1987) 7.43
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem (2000) 5.75
Quantitation of human immunodeficiency virus type 1 infection kinetics. J Virol (1993) 5.17
Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY. Nat Genet (1997) 4.19
Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat Genet (1997) 3.89
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J Biol Chem (1997) 3.74
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science (1996) 3.70
Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science (1990) 3.27
Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells. Proc Natl Acad Sci U S A (1998) 2.96
A retrospective study on transmission of adult T cell leukemia virus by blood transfusion: seroconversion in recipients. Vox Sang (1984) 2.91
Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure. J Am Coll Cardiol (1994) 2.89
Separation and purification of the hemagglutinins from Bordetella pertussis. Infect Immun (1983) 2.85
Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding. Cell (1987) 2.84
Role of antibody to leukocytosis-promoting factor hemagglutinin and to filamentous hemagglutinin in immunity to pertussis. Infect Immun (1981) 2.77
Bordetella pertussis infection in mice: correlation of specific antibodies against two antigens, pertussis toxin, and filamentous hemagglutinin with mouse protectivity in an intracerebral or aerosol challenge system. Infect Immun (1984) 2.72
Microtubular origin of mitotic spindle form birefringence. Demonstration of the applicability of Wiener's equation. J Cell Biol (1975) 2.59
Monoclonal antibody against pertussis toxin: effect on toxin activity and pertussis infections. Infect Immun (1984) 2.59
Ischemic preconditioning increases adenosine release and 5'-nucleotidase activity during myocardial ischemia and reperfusion in dogs. Implications for myocardial salvage. Circulation (1993) 2.56
Results of a nationwide study on the three-field lymph node dissection of esophageal cancer. Oncology (1991) 2.54
Leukemia-associated transplantation antigens related to murine leukemia virus. The X.1 system: immune response controlled by a locus linked to H-2. J Exp Med (1973) 2.52
Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in a nasopharyngeal carcinoma. J Virol (1990) 2.43
Isolation and characterization of fra-2, an additional member of the fos gene family. Proc Natl Acad Sci U S A (1990) 2.40
Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust. Toxicol Appl Pharmacol (2001) 2.40
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A (1997) 2.35
Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system. Gene Ther (1999) 2.34
Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis. Ann Rheum Dis (2007) 2.33
Aerosol infection of mice with Bordetella pertussis. Infect Immun (1980) 2.31
Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. Cancer Res (1997) 2.28
Interactions between endogenous gamma interferon and tumor necrosis factor in host resistance against primary and secondary Listeria monocytogenes infections. Infect Immun (1989) 2.28
Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion. EMBO J (2001) 2.23
Vinblastine and griseofulvin reversibly disrupt the living mitotic spindle. Science (1968) 2.19
Heptakis(2,6-O-dimethyl)beta-cyclodextrin: a novel growth stimulant for Bordetella pertussis phase I. J Clin Microbiol (1983) 2.17
Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells. Cancer Res (1988) 2.17
Immunohistochemical characterization of glomerular IgA deposits in IgA nephropathy. Clin Nephrol (1990) 2.09
Effect of heptakis (2,6-O-dimethyl) beta-cyclodextrin on the production of pertussis toxin by Bordetella pertussis. Infect Immun (1983) 2.06
Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family. J Biol Chem (1995) 2.01
Analysis of genes for bilirubin UDP-glucuronosyltransferase in Gilbert's syndrome. Lancet (1995) 2.01
Somatostatin: abundance of immunoreactive hormone in rat stomach and pancreas. Science (1975) 2.00
Spontaneous proliferation of peripheral blood lymphocytes increased in patients with HTLV-I-associated myelopathy. Neurology (1988) 1.96
Immune response of Brazilian children to a Neisseria meningitidis serogroup B outer membrane protein vaccine: comparison with efficacy. Infect Immun (1994) 1.96
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. FASEB J (2000) 1.93
Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. Proc Natl Acad Sci U S A (2000) 1.89
The C-terminal region of membrane type matrix metalloproteinase is a functional transmembrane domain required for pro-gelatinase A activation. J Biol Chem (1995) 1.84
Inhibitory effects of quinolone antibacterial agents on gamma-aminobutyric acid binding to receptor sites in rat brain membranes. Antimicrob Agents Chemother (1988) 1.83
Essential structure of E. coli promoter: effect of spacer length between the two consensus sequences on promoter function. Nucleic Acids Res (1983) 1.80
Prevalence of non-alcoholic fatty liver disease and its association with impaired glucose metabolism in Japanese adults. Diabet Med (2005) 1.77
Critical period for monocular deprivation in the cat visual cortex. J Neurophysiol (1992) 1.75
The expression of matrix metalloproteinase 9 is enhanced by Epstein-Barr virus latent membrane protein 1. Proc Natl Acad Sci U S A (1998) 1.75
Genetic mapping of the Fv-1 lcous of the mouse. Science (1973) 1.75
Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res (1995) 1.72
Apolipoprotein E Sendai (arginine 145-->proline): a new variant associated with lipoprotein glomerulopathy. J Am Soc Nephrol (1997) 1.71
Simple excision and closure of a distal limb of loop colostomy prolapse by stapler device. Tech Coloproctol (2011) 1.70
Quantification of glomerular TGF-beta 1 mRNA in patients with diabetes mellitus. Kidney Int (1996) 1.67
Implications of prodromal angina pectoris in anterior wall acute myocardial infarction: acute angiographic findings and long-term prognosis. J Am Coll Cardiol (1997) 1.66
Beneficial effect of prodromal angina pectoris is lost in elderly patients with acute myocardial infarction. Am Heart J (2000) 1.66
Remitting seronegative symmetrical synovitis with pitting edema associated with gastric carcinoma. J Rheumatol (1997) 1.64
Effect of monoclonal antibody to pertussis toxin on toxin activity. Infect Immun (1987) 1.61
Participation of macrophages in segmental endocapillary proliferation preceding focal glomerular sclerosis. J Pathol (1993) 1.60
Role of oxygen-derived free radicals in myocardial edema and ischemia in coronary microvascular embolization. Circulation (1991) 1.60
Increased serum concentrations of tissue inhibitor of metalloproteinase-1 in COPD patients. Eur Respir J (2005) 1.60
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res (1997) 1.60
Discrimination of brain abscess from necrotic or cystic tumors by diffusion-weighted echo planar imaging. Magn Reson Imaging (1996) 1.59
Radiocesium in children residing in the western districts of the Bryansk Oblast from 1991-1996. Health Phys (2000) 1.59
TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads. J Biol Chem (1998) 1.59
Three-field lymph node dissection for esophageal cancer in elderly patients over 70 years of age. Ann Thorac Surg (2001) 1.59
Adjusted prognostic association of depression following myocardial infarction with mortality and cardiovascular events: individual patient data meta-analysis. Br J Psychiatry (2013) 1.58
Genetically encoded fluorescent sensors of membrane potential. Brain Cell Biol (2008) 1.57
Pertussis toxin S1 mutant with reduced enzyme activity and a conserved protective epitope. Science (1988) 1.56
The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death. Oncogene (2007) 1.55
Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population. Diabetologia (2007) 1.55
Clinical utility of anti-signal recognition particle antibody in the differential diagnosis of myopathies. Rheumatology (Oxford) (2008) 1.53
Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II. Biochim Biophys Acta (1998) 1.52
Mutational analysis of human papillomavirus type 16 E7 functions. J Virol (1990) 1.52
Transfer of measles, mumps, and rubella antibodies from mother to infant. Its effect on measles, mumps, and rubella immunization. Am J Dis Child (1979) 1.51
Lack of evidence for bromocriptine effect on glucose tolerance, insulin resistance, and body fat stores in obese type 2 diabetic patients. Diabetes Care (2000) 1.49
Activities of complete and truncated forms of pertussis toxin subunits S1 and S2 synthesized by Escherichia coli. Infect Immun (1987) 1.49
Bone marrow fat cell enlargement and a rise in intraosseous pressure in steroid-treated rabbits with osteonecrosis. Bone (2002) 1.49
Pleomorphic leiomyosarcoma: clinicopathologic and immunohistochemical study with special emphasis on its distinction from ordinary leiomyosarcoma and malignant fibrous histiocytoma. Am J Surg Pathol (2001) 1.48
Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. Int J Cancer (1995) 1.48
Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese. Intern Med (1999) 1.48
Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase. Proc Natl Acad Sci U S A (2001) 1.48
Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human urothelial carcinomas. J Urol (1998) 1.48
The regional distribution of somatostatin in the rat brain. Endocrinology (1975) 1.48
Perspectives in pharmacokinetics. Physiologically based pharmacokinetic modeling as a tool for drug development. J Pharmacokinet Biopharm (1995) 1.47
Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: implications for bone resorption. Lab Invest (1995) 1.46
Time course of impaired coronary flow reserve after reperfusion in patients with acute myocardial infarction. Am J Cardiol (1996) 1.46
Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2. Cancer Res (1996) 1.45
A diabetic case with hemoglobin J-Meerut and low HbA1C levels. Intern Med (1997) 1.45
Screening of blood donors for human parvovirus B19. Lancet (1995) 1.45
Bronchial sleeve resection with complete preservation of the lung for carcinoma. Respiration (2001) 1.44
Heme oxygenase-carbon monoxide signalling pathway in atherosclerosis: anti-atherogenic actions of bilirubin and carbon monoxide? Cardiovasc Res (1999) 1.44
The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor. Int J Cancer (1998) 1.44
Human parvovirus B19 induces cell cycle arrest at G(2) phase with accumulation of mitotic cyclins. J Virol (2001) 1.43